Publication

A retrospective study of 69 patients with t(6;9)(p23;q34) AML emphasizes the need for a prospective, multicenter initiative for rare 'poor prognosis' myeloid malignancies.

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Leukemia2006PMID 16628187stubpubmedPublished

Abstract

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Linked entities

Linked entities (2)

How each link was made (MeSH, dictionary, registry reference, curation…) and whether it has been validated. Candidate links are not counted in entity statistics.

Validated 2

geneNUP214civic_curation1.00
variantNUP214 Fusioncivic_curation1.00

Curated evidence

Evidence citing this paper (2)

civicCuratedShowing 1–2 of 2 evidence items · levels, directions and significance as curated at the source; each row links to its CIViC record.

Therapy	Cancer	Type	Level	Direction · significance	Rating (1–5)	Status	Evidence	Source
NUP214 Fusion2
(diagnostic)	Acute Myeloid Leukemia With T(6;9) (p23;q34.1)UNRESOLVED	Diagnostic	B	Supports Positive	4	accepted	EID12123 This retrospective study from five independent study sites gathered diagnostic and prognostic data regarding the t(6;9)(p23;q34), known to result in a DEK::NUP214 fusion. Data from 20 different treatm… (full text at CIViC) PMID 16628187 · Slovak et al., 2006 · Open in CIViC	civic
(prognostic)	Acute Myeloid Leukemia With T(6;9) (p23;q34.1)UNRESOLVED	Prognostic	B	Supports Poor Outcome	4	submitted	EID12124 This retrospective study gathered diagnostic and prognostic data for acute myeloid leukemia (AML) with the t(6;9)(p23;q34), known to result in a DEK::NUP214 fusion from 20 different treatment protocol… (full text at CIViC) PMID 16628187 · Slovak et al., 2006 · Open in CIViC	civic