Publication
Novel fibroblast growth factor receptor 3 (FGFR3) mutations in bladder cancer previously identified in non-lethal skeletal disorders.
Authors not recorded
- Source
- PubMed
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CIVIC-20260908-000001
Abstract
Abstract (excerpt)
Only the opening of the abstract is shown; abstract text may carry publisher copyright.
Data not yet available
Linked entities
Linked entities (3)
How each link was made (MeSH, dictionary, registry reference, curation…) and whether it has been validated. Candidate links are not counted in entity statistics.
Validated 3
- cancerMalignant Bladder Neoplasmcivic_curation1.00
- geneFGFR3civic_curation1.00
- variantFGFR3 G380Rcivic_curation1.00
Curated evidence
Evidence citing this paper (3)
- Source
- CIViC — Clinical Interpretation of Variants in Cancer
- Dataset
- CIViC evidence items
- Version
- civic-2026-09-08
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- expert curation
- License
- CC0 1.0
- PMID
- 12461689
- Run
- ING-CIVIC-20260908-000001
| Therapy | Cancer | Type | Level | Direction · significance | Rating (1–5) | Status | Evidence | Source |
|---|---|---|---|---|---|---|---|---|
| FGFR3 G380R1 | ||||||||
| (oncogenic) | Malignant Bladder NeoplasmALIAS | Oncogenic | C | Supports Oncogenicity | 1 | accepted | EID10490Targeted mutation analysis on the FGFR3 gene in 297 bladder cancer patients was conducted, where 177 patients were found to harbor FGFR3 mutations. One patient was found to harbor a novel G380R mutati… (full text at CIViC) PMID 12461689 · van Rhijn et al., 2002 · Open in CIViC | civic |
| FGFR3 K650M1 | ||||||||
| (oncogenic) | Malignant Bladder NeoplasmALIAS | Oncogenic | C | Supports Oncogenicity | 1 | submitted | EID10491Targeted mutation analysis on the FGFR3 gene in 297 bladder cancer patients was conducted, where 177 patients were found to harbor FGFR3 mutations. Two patients were found to harbor the K650M variant … (full text at CIViC) PMID 12461689 · van Rhijn et al., 2002 · Open in CIViC | civic |
| FGFR3 K650T1 | ||||||||
| (oncogenic) | Malignant Bladder NeoplasmALIAS | Oncogenic | C | Supports Oncogenicity | 1 | submitted | EID10492Targeted mutation analysis on the FGFR3 gene in 297 bladder cancer patients was conducted, where 177 patients were found to harbor FGFR3 mutations. Among those patients, one harbored the K650T variant… (full text at CIViC) PMID 12461689 · van Rhijn et al., 2002 · Open in CIViC | civic |