Knowledge graph · Trial
Study of the CHK1 Inhibitor BBI-355, an ecDNA-directed Therapy (ecDTx), and the RNR Inhibitor BBI-825, in Subjects With Tumors With Oncogene Amplifications
TERMINATED
- Identifier
- CI-TRIAL-00122823
- Entity page
- /trial/NCT05827614 ↗
- Edges
- 10
- Neighbours
- 8 cancers2 drugs
- Drawn
- 10 of 10 neighbours (cap 60); table lists every fetched edge
Accepted: cancer:<slug>, gene:<symbol>, variant:<slug>, drug:<slug>, trial:<NCT id>, or a bare CI id. Find slugs with search.
Most connectedLung Non-Small Cell Carcinoma 3,149Malignant Colorectal Neoplasm 1,866ABL1 298EGFR 276Imatinib 450Dasatinib 321
Neighbourhood
Radial view
Focus at the centre; neighbours grouped by entity type. Click a node to re-centre the graph on it; ↗ opens the entity page. Hover a spoke for relationship, evidence level, cancer context and source.
Edges
Every edge, grouped by relationship
Source-native edges first (aggregated per neighbour, direction, evidence level and source), then derived registry links. Up to 15 per relationship (10 trials); “show all” raises one group to 200.
| Relationship | Neighbour | Direction | Evidence level | Cancer context | Support | Claim | Source | Expand |
|---|---|---|---|---|---|---|---|---|
| Study of the CHK1 Inhibitor BBI-355, an ecDNA-directed Therapy (ecDTx), and the RNR Inhibitor BBI-825, in Subjects With Tumors With Oncogene Amplifications condition of …CONDITION_OFderived8 of 8 | ||||||||
| ← condition of | Cervical Squamous Cell Carcinoma registry condition “Cervical Squamous Cell Carcinoma” mapped CURATED_BROADER | — | — | Cervical Squamous Cell Carcinoma | 1 | Observed | clinicaltrials | graph → |
| ← condition of | Head and Neck Squamous Cell Carcinoma registry condition “Head and Neck (HNSCC)” mapped ALIAS | |||||||