ADGRV1

adhesion G protein-coupled receptor V1

Identifier: CI-GENE-00000554
Entity page: /gene/ADGRV1 ↗
Edges: 46

Neighbours: 23 cancers15 variants
Drawn: 38 of 38 neighbours (cap 60); table lists every fetched edge

Accepted: cancer:<slug>, gene:<symbol>, variant:<slug>, drug:<slug>, trial:<NCT id>, or a bare CI id. Find slugs with search.

Most connectedLung Non-Small Cell Carcinoma 3,147 Malignant Colorectal Neoplasm 1,866 ABL1 298 EGFR 276 Imatinib 450 Dasatinib 321

Neighbourhood

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Source-native edges first (aggregated per neighbour, direction, evidence level and source), then derived registry links. Up to 15 per relationship (10 trials); “show all” raises one group to 200.

Relationship	Neighbour	Direction	Evidence level	Cancer context	Support	Claim	Source	Expand
ADGRV1 has variant …HAS_VARIANTderived15 of 23show all (up to 200)
→ has variant	NM_032119.4(ADGRV1):c.11940+78A>GSNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_032119.4(ADGRV1):c.11941-47C>GSNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0

ADGRV1 altered in cohorts of …ALTERED_INderived23 of 23show fewer
→ altered in cohorts of	Skin Basal Cell Carcinoma 82 / 126 cases (65 %) · ssm · bcc_unige_2016	—	—	Skin Basal Cell Carcinoma	1	Observed	cbioportal	graph →
→ altered in cohorts of	Cutaneous Melanoma 166 / 469 cases (35 %) · ssm · skcm_tcga_gdc · largest of 8 cohorts	—	—	Cutaneous Melanoma	8	Observed	cbioportal	graph →
→ altered in cohorts of	Melanoma 43 / 144 cases (30 %) · ssm · mel_dfci_2019 · largest of 2 cohorts	—	—	Melanoma	2	Observed	cbioportal	graph →
→ altered in cohorts of	Skin Squamous Cell Carcinoma 20 / 83 cases (24 %) · ssm · cscc_ucsf_2021 · largest of 3 cohorts	—	—	Skin Squamous Cell Carcinoma	3	Observed	cbioportal	graph →
→ altered in cohorts of	Renal Cell Carcinoma 34 / 158 cases (22 %) · ssm · rcc_iatlas_immotion150_2018	—	—	Renal Cell Carcinoma	1	Observed	cbioportal	graph →
→ altered in cohorts of	Endometrial Carcinoma 86 / 517 cases (17 %) · ssm · ucec_tcga_pan_can_atlas_2018 · largest of 4 cohorts	—	—	Endometrial Carcinoma	4	Observed	cbioportal	graph →
→ altered in cohorts of	Lung Squamous Cell Carcinoma 80 / 484 cases (17 %) · ssm · lusc_tcga_pan_can_atlas_2018 · largest of 4 cohorts	—	—	Lung Squamous Cell Carcinoma	4	Observed	cbioportal	graph →
→ altered in cohorts of	Colon Adenocarcinoma 65 / 429 cases (15 %) · ssm · coad_tcga_gdc · largest of 2 cohorts	—	—	Colon Adenocarcinoma	2	Observed	cbioportal	graph →
→ altered in cohorts of	Invasive Breast Carcinoma 20 / 134 cases (15 %) · ssm · brca_aurora_2023	—	—	Invasive Breast Carcinoma	1	Observed	cbioportal	graph →
→ altered in cohorts of	Endometrial Endometrioid Adenocarcinoma 35 / 247 cases (14 %) · ssm · uec_cptac_gdc	—	—	Endometrial Endometrioid Adenocarcinoma	1	Observed	cbioportal	graph →
→ altered in cohorts of	Lung Non-Small Cell Carcinoma 147 / 1,144 cases (13 %) · ssm · nsclc_tcga_broad_2016	—	—	Lung Non-Small Cell Carcinoma	1	Observed	cbioportal	graph →
→ altered in cohorts of	Gastroesophageal Junction Adenocarcinoma 65 / 518 cases (13 %) · ssm · stes_tcga_pub	—	—	Gastroesophageal Junction Adenocarcinoma	1	Observed	cbioportal	graph →
→ altered in cohorts of	Esophageal Adenocarcinoma 22 / 185 cases (12 %) · ssm · esca_tcga	—	—	Esophageal Adenocarcinoma	1	Observed	cbioportal	graph →
→ altered in cohorts of	Gastric Adenocarcinoma 53 / 478 cases (11 %) · ssm · stad_tcga · largest of 4 cohorts	—	—	Gastric Adenocarcinoma	4	Observed	cbioportal	graph →
→ altered in cohorts of	Cervical Squamous Cell Carcinoma 30 / 291 cases (10 %) · ssm · cesc_tcga_pan_can_atlas_2018 · largest of 3 cohorts	—	—	Cervical Squamous Cell Carcinoma	3	Observed	cbioportal	graph →
→ altered in cohorts of	Lung Adenocarcinoma 55 / 566 cases (9.7 %) · ssm · luad_tcga_pan_can_atlas_2018	—	—	Lung Adenocarcinoma	1	Observed	cbioportal	graph →
→ altered in cohorts of	Hepatocellular Carcinoma 47 / 494 cases (9.5 %) · ssm · hcc_clca_2024 · largest of 5 cohorts	—	—	Hepatocellular Carcinoma	5	Observed	cbioportal	graph →
→ altered in cohorts of	Diffuse Glioma 58 / 629 cases (9.2 %) · ssm · difg_glass · largest of 2 cohorts	—	—	Diffuse Glioma	2	Observed	cbioportal	graph →
→ altered in cohorts of	Bladder Urothelial Carcinoma 36 / 474 cases (7.6 %) · ssm · blca_msk_tcga_2020 · largest of 5 cohorts	—	—	Bladder Urothelial Carcinoma	5	Observed	cbioportal	graph →
→ altered in cohorts of	Head and Neck Squamous Cell Carcinoma 39 / 515 cases (7.6 %) · ssm · hnsc_tcga_pan_can_atlas_2018 · largest of 4 cohorts	—	—	Head and Neck Squamous Cell Carcinoma	4	Observed	cbioportal	graph →
→ altered in cohorts of	Colorectal Adenocarcinoma 72 / 1,015 cases (7.1 %) · ssm · crc_sysucc_2022 · largest of 2 cohorts	—	—	Colorectal Adenocarcinoma	2	Observed	cbioportal	graph →
→ altered in cohorts of	B-Cell Non-Hodgkin Lymphoma 21 / 297 cases (7.1 %) · ssm · mbn_sfu_2023	—	—	B-Cell Non-Hodgkin Lymphoma	1	Observed	cbioportal	graph →
→ altered in cohorts of	Cholangiocarcinoma 24 / 417 cases (5.8 %) · ssm · chol_icgc_2017	—	—	Cholangiocarcinoma	1	Observed	cbioportal	graph →

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