| Avapritinib studied in …STUDIED_INderived22 of 22show fewer |
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| → studied in | NCT07131059NA · recruiting MRD-positive AML Clinical Study · 22 trials list this drug (10 active) | — | — | Adult Acute Myeloid Leukemia | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04116541Phase 2 · recruiting A Study Evaluating the Activity of Anti-cancer Treatments Targeting Tumor Molecular Alterations/Characteristics in Advanced / Metastatic Tumors. · 22 trials list this drug (10 active) | — | — | Malignant Solid Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04771520Phase 2 · recruiting Avapritinib for the Treatment of CKIT or PDGFRA Mutation-Positive Locally Advanced or Metastatic Malignant Solid Tumors · 22 trials list this drug (10 active) | — | — | Malignant Solid Neoplasm,Melanoma,Sarcoma+2 | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03580655Phase 2 · completed (PATHFINDER) Study to Evaluate Efficacy and Safety of Avapritinib (BLU-285), A Selective KIT Mutation-targeted Tyrosine Kinase Inhibitor, in Patients With Advanced Systemic Mastocytosis · 22 trials list this drug (10 active) | — | — | Malignant Mastocytosis,Aggressive Systemic Mastocytosis,Mast Cell Leukemia+1 | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT07255638recruiting A Non-Interventional Study in Participants With Indolent Systemic Mastocytosis (ISM) in Germany · 22 trials list this drug (10 active) | — | — | Indolent Systemic Mastocytosis | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT06327685Phase 1 · recruiting Avapritinib With Decitabine in Patients With SM-AHN · 22 trials list this drug (10 active) | — | — | Systemic Mastocytosis with an Associated Myeloid Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05381753completed Safety and Efficacy of Avapritinib in Chinese Patients With Gastrointestinal Stromal Tumor (GIST) in the Real World · 22 trials list this drug (10 active) | — | — | Gastrointestinal Stromal Tumor | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT06748001Phase 4 · recruiting Avapritinib Rollover Study · 22 trials list this drug (10 active) | — | — | Systemic Mastocytosis | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04773782Phase 1/Phase 2 · completed A Study of Avapritinib in Pediatric Patients With Solid Tumors Dependent on KIT or PDGFRA Signaling · 22 trials list this drug (10 active) | — | — | Solid Neoplasm,Central Nervous System Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03731260Phase 2 · active not recruiting (PIONEER) Study to Evaluate Efficacy and Safety of Avapritinib (BLU-285), A Selective KIT Mutation-targeted Tyrosine Kinase Inhibitor, Versus Placebo in Patients With Indolent Systemic Mastocytosis · 22 trials list this drug (10 active) | — | — | Indolent Systemic Mastocytosis | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT06765915Phase 2 · not yet recruiting Avapritinib Maintenance for AML With KIT Mutations · 22 trials list this drug (10 active) | — | — | Adult Acute Myeloid Leukemia | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04908176Phase 1 · completed A Drug-drug Interaction Study of Avapritinib and Midazolam · 22 trials list this drug (10 active) | — | — | Gastrointestinal Stromal Tumor | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04825574Phase 4 · completed Study for Patients Previously Treated in Avapritinib Clinical Trials · 22 trials list this drug (10 active) | — | — | Gastrointestinal Stromal Tumor | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04714086no longer available Expanded Access Program for Avapritinib · 22 trials list this drug (10 active) | — | — | Solid Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT06221683Phase 2 · recruiting Clinical Study of Induction Therapy Options Based on Molecular Subtyping and MRD in Children and Adolescents With AML · 22 trials list this drug (10 active) | — | — | Acute Myeloid Leukemia,Childhood Acute Myeloid Leukemia | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT06316960Phase 2 · recruiting Safety and Efficacy of Avapritinib in Relapsed or Refractory Pediatric CBF-AML With KIT Mutation · 22 trials list this drug (10 active) | — | — | Acute Myeloid Leukemia,Childhood Acute Myeloid Leukemia,Core Binding Factor Acute Myeloid Leukemia | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05821738Phase 2 · unknown Avapritinib in CBF-AML With KIT Mutations · 22 trials list this drug (10 active) | — | — | Core Binding Factor Acute Myeloid Leukemia | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04254939Phase 1/Phase 2 · completed A Study of CS3007 in Subjects With Gastrointestinal Stromal Tumor · 22 trials list this drug (10 active) | — | — | Gastrointestinal Stromal Tumor | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02561988Phase 1 · completed (EXPLORER) Study of BLU-285 in Patients With Advanced Systemic Mastocytosis (AdvSM) and Relapsed or Refractory Myeloid Malignancies · 22 trials list this drug (10 active) | — | — | Aggressive Systemic Mastocytosis,Mast Cell Leukemia | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03465722Phase 3 · completed (VOYAGER) Study of Avapritinib vs Regorafenib in Patients With Locally Advanced Unresectable or Metastatic GIST · 22 trials list this drug (10 active) | — | — | Gastrointestinal Stromal Tumor | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02508532Phase 1 · completed (NAVIGATOR) Study of BLU-285 in Patients With Gastrointestinal Stromal Tumors (GIST) and Other Relapsed and Refractory Solid Tumors · 22 trials list this drug (10 active) | — | — | Gastrointestinal Stromal Tumor | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03862885approved for marketing Early Access Program (EAP) for Avapritinib in Patients With Locally Advanced Unresectable or Metastatic GIST · 22 trials list this drug (10 active) | — | — | Gastrointestinal Stromal Tumor | 1 | Observed | clinicaltrials | graph → |