Retinal Neoplasm

cancer family

Identifier: CI-CAN-00000340
Entity page: /cancer/retinal-neoplasm ↗
Edges: 145

Neighbours: 1 genes28 drugs10 trials
Drawn: 39 of 39 neighbours (cap 60); table lists every fetched edge

Accepted: cancer:<slug>, gene:<symbol>, variant:<slug>, drug:<slug>, trial:<NCT id>, or a bare CI id. Find slugs with search.

Most connectedLung Non-Small Cell Carcinoma 3,147 Malignant Colorectal Neoplasm 1,866 ABL1 298 EGFR 276 Imatinib 450 Dasatinib 321

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Relationship	Neighbour	Direction	Evidence level	Cancer context	Support	Claim	Source	Expand
Retinal Neoplasm approved for …APPROVED_FORderived1 of 1
← approved for	Cyclophosphamidesmall molecule FDA (US) · approved · 2023-09-12 · retinoblastoma	—	approved	Retinoblastoma	1	Regulatory	openfda	graph →
Retinal Neoplasm investigated for …INVESTIGATED_FOR2 of 2

Retinal Neoplasm altered in cohorts of …ALTERED_INderived1 of 1
← altered in cohorts of	RB1 52 / 83 cases (63 %) · ssm · rbl_mskcc_2020	—	—	Retinoblastoma	1	Observed	cbioportal	graph →

Retinal Neoplasm altered in cohorts of …ALTERED_INderived1 of 1

← altered in cohorts of

RB1

52 / 83 cases (63 %) · ssm · rbl_mskcc_2020

—

Retinoblastoma

Observed

Retinal Neoplasm investigated in trials for …INVESTIGATED_IN_TRIALSderived28 of 28show fewer
→ investigated in trials for	Carboplatinsmall_molecule 15 trials (3 active) · roll-up of the cancer and its descendants	—	—	Retinal Neoplasm	15	Observed	clinicaltrials	graph →
→ investigated in trials for	Etoposidesmall molecule 13 trials (3 active) · roll-up of the cancer and its descendants	—	—	Retinal Neoplasm	13	Observed	clinicaltrials	graph →
→ investigated in trials for	Filgrastimother 12 trials (1 active) · roll-up of the cancer and its descendants	—	—	Retinal Neoplasm	12	Observed	clinicaltrials	graph →
→ investigated in trials for	Melphalansmall_molecule 11 trials (4 active) · roll-up of the cancer and its descendants	—	—	Retinal Neoplasm	11	Observed	clinicaltrials	graph →
→ investigated in trials for	Vincristinesmall molecule 10 trials (3 active) · roll-up of the cancer and its descendants	—	—	Retinal Neoplasm	10	Observed	clinicaltrials	graph →
→ investigated in trials for	Topotecansmall molecule 8 trials (3 active) · roll-up of the cancer and its descendants	—	—	Retinal Neoplasm	8	Observed	clinicaltrials	graph →
→ investigated in trials for	Cyclophosphamidesmall molecule 7 trials (2 active) · roll-up of the cancer and its descendants	—	—	Retinal Neoplasm	7	Observed	clinicaltrials	graph →
→ investigated in trials for	Thiotepasmall molecule 7 trials (1 active) · roll-up of the cancer and its descendants	—	—	Retinal Neoplasm	7	Observed	clinicaltrials	graph →
→ investigated in trials for	Busulfansmall molecule 4 trials (0 active) · roll-up of the cancer and its descendants	—	—	Retinal Neoplasm	4	Observed	clinicaltrials	graph →
→ investigated in trials for	Chemotherapy 2 trials (0 active) · roll-up of the cancer and its descendants	—	—	Retinal Neoplasm	2	Observed	clinicaltrials	graph →
→ investigated in trials for	Cisplatinsmall molecule 2 trials (0 active) · roll-up of the cancer and its descendants	—	—	Retinal Neoplasm	2	Observed	clinicaltrials	graph →
→ investigated in trials for	Dexamethasonesmall molecule 2 trials (0 active) · roll-up of the cancer and its descendants	—	—	Retinal Neoplasm	2	Observed	clinicaltrials	graph →
→ investigated in trials for	Doxorubicinsmall molecule 2 trials (1 active) · roll-up of the cancer and its descendants	—	—	Retinal Neoplasm	2	Observed	clinicaltrials	graph →
→ investigated in trials for	Ifosfamidesmall molecule 2 trials (0 active) · roll-up of the cancer and its descendants	—	—	Retinal Neoplasm	2	Observed	clinicaltrials	graph →
→ investigated in trials for	Temozolomidesmall molecule 2 trials (0 active) · roll-up of the cancer and its descendants	—	—	Retinal Neoplasm	2	Observed	clinicaltrials	graph →
→ investigated in trials for	Alvocidibsmall molecule 1 trials (0 active) · roll-up of the cancer and its descendants	—	—	Retinal Neoplasm	1	Observed	clinicaltrials	graph →
→ investigated in trials for	Arsenic Trioxidesmall molecule 1 trials (0 active) · roll-up of the cancer and its descendants	—	—	Retinal Neoplasm	1	Observed	clinicaltrials	graph →
→ investigated in trials for	Cixutumumabmonoclonal antibody 1 trials (0 active) · roll-up of the cancer and its descendants	—	—	Retinal Neoplasm	1	Observed	clinicaltrials	graph →
→ investigated in trials for	Cytarabinesmall molecule 1 trials (0 active) · roll-up of the cancer and its descendants	—	—	Retinal Neoplasm	1	Observed	clinicaltrials	graph →
→ investigated in trials for	Leucovorinsmall molecule 1 trials (0 active) · roll-up of the cancer and its descendants	—	—	Retinal Neoplasm	1	Observed	clinicaltrials	graph →
→ investigated in trials for	Methotrexatesmall molecule 1 trials (0 active) · roll-up of the cancer and its descendants	—	—	Retinal Neoplasm	1	Observed	clinicaltrials	graph →
→ investigated in trials for	Paclitaxelsmall molecule 1 trials (0 active) · roll-up of the cancer and its descendants	—	—	Retinal Neoplasm	1	Observed	clinicaltrials	graph →
→ investigated in trials for	Pegfilgrastimother 1 trials (1 active) · roll-up of the cancer and its descendants	—	—	Retinal Neoplasm	1	Observed	clinicaltrials	graph →
→ investigated in trials for	Pembrolizumabmonoclonal antibody 1 trials (1 active) · roll-up of the cancer and its descendants	—	—	Retinal Neoplasm	1	Observed	clinicaltrials	graph →
→ investigated in trials for	Pomalidomidesmall molecule 1 trials (0 active) · roll-up of the cancer and its descendants	—	—	Retinal Neoplasm	1	Observed	clinicaltrials	graph →
→ investigated in trials for	Sirolimussmall molecule 1 trials (0 active) · roll-up of the cancer and its descendants	—	—	Retinal Neoplasm	1	Observed	clinicaltrials	graph →
→ investigated in trials for	Thalidomidesmall molecule 1 trials (0 active) · roll-up of the cancer and its descendants	—	—	Retinal Neoplasm	1	Observed	clinicaltrials	graph →
→ investigated in trials for	Vatalanibsmall molecule 1 trials (0 active) · roll-up of the cancer and its descendants	—	—	Retinal Neoplasm	1	Observed	clinicaltrials	graph →

Retinal Neoplasm studied in …STUDIED_INderived10 of 113show all (up to 200)
→ studied in	NCT01109394recruiting Comprehensive Omics Analysis of Pediatric and Adult Solid Tumors and Establishment of a Repository for Related Biological Studies · condition mapped ONTOLOGY_EXACT · 113 trials mapped (28 active)	—	—	Retinoblastoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT03016156NA · terminated Determination of the Sensitivity and Specificity of a Smartphone Application to Detect Retinoblastoma · condition mapped ONTOLOGY_EXACT · 113 trials mapped (28 active)	—	—	Retinoblastoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT05504291Phase 2 · recruiting A Study to Give Treatment Inside the Eye to Treat Retinoblastoma · condition mapped CURATED_BROADER · 113 trials mapped (28 active)	—	—	Retinoblastoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT05650749Phase 1 · enrolling by invitation GPC2 CAR T Cells for Relapsed or Refractory Neuroblastoma and Metastatic Retinoblastoma · condition mapped ONTOLOGY_EXACT · 113 trials mapped (28 active)	—	—	Retinoblastoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT03655223active not recruiting Early Check: Expanded Screening in Newborns · condition mapped ONTOLOGY_EXACT · 113 trials mapped (28 active)	—	—	Retinoblastoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT01783535Phase 2 · active not recruiting Protocol for the Study and Treatment of Participants With Intraocular Retinoblastoma · condition mapped ONTOLOGY_EXACT · 113 trials mapped (28 active)	—	—	Retinoblastoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT03050268recruiting Familial Investigations of Childhood Cancer Predisposition · condition mapped ONTOLOGY_EXACT · 113 trials mapped (28 active)	—	—	Retinoblastoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT04458935completed Retrospective Case Series of Trans-scleral Cryotherapy for Retinal Hemangioblastoma · condition mapped ONTOLOGY_EXACT · 113 trials mapped (28 active)	—	—	Retinal Hemangioblastoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT03546387recruiting Determining Whether Multiple Anesthesia Exposures Affect Cognitive Function for Retinoblastoma Patients · condition mapped ONTOLOGY_EXACT · 113 trials mapped (28 active)	—	—	Retinoblastoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT06679634Phase 2 · recruiting Retinoblastoma Phase II Expanded Access Clinical Trial · condition mapped ONTOLOGY_EXACT · 113 trials mapped (28 active)	—	—	Retinoblastoma	1	Observed	clinicaltrials	graph →

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