PEComa

subtype

Identifier: CI-CAN-00003639
Entity page: /cancer/pecoma ↗
Edges: 82

Neighbours: 1 genes1 variants17 drugs10 trials
Drawn: 29 of 29 neighbours (cap 60); table lists every fetched edge

Accepted: cancer:<slug>, gene:<symbol>, variant:<slug>, drug:<slug>, trial:<NCT id>, or a bare CI id. Find slugs with search.

Most connectedLung Non-Small Cell Carcinoma 3,147 Malignant Colorectal Neoplasm 1,866 ABL1 298 EGFR 276 Imatinib 450 Dasatinib 321

Neighbourhood

Radial view

Focus at the centre; neighbours grouped by entity type. Click a node to re-centre the graph on it; ↗ opens the entity page. Hover a spoke for relationship, evidence level, cancer context and source.

Edges

Every edge, grouped by relationship

Source-native edges first (aggregated per neighbour, direction, evidence level and source), then derived registry links. Up to 15 per relationship (10 trials); “show all” raises one group to 200.

Relationship	Neighbour	Direction	Evidence level	Cancer context	Support	Claim	Source	Expand
PEComa diagnostic of …DIAGNOSTIC_OF1 of 1
← diagnostic of	TFE3 Fusionfusion 3 source records aggregated	supports	B	PEComa	3	Curated	civic	graph →
PEComa associated with …ASSOCIATED_WITH1 of 1
← associated with

PEComa investigated for …INVESTIGATED_FOR1 of 1
← investigated for	Sirolimussmall_molecule	unknown	2	PEComa	1	Curated	chembl	graph →

PEComa investigated for …INVESTIGATED_FOR1 of 1

← investigated for

Sirolimussmall_molecule

unknown

PEComa

Curated

PEComa investigated in trials for …INVESTIGATED_IN_TRIALSderived17 of 17show fewer
→ investigated in trials for	Sirolimussmall_molecule 10 trials (2 active) · roll-up of the cancer and its descendants	—	—	PEComa	10	Observed	clinicaltrials	graph →
→ investigated in trials for	Everolimussmall molecule 6 trials (2 active) · roll-up of the cancer and its descendants	—	—	PEComa	6	Observed	clinicaltrials	graph →
→ investigated in trials for	Nivolumabmonoclonal antibody 2 trials (1 active) · roll-up of the cancer and its descendants	—	—	PEComa	2	Observed	clinicaltrials	graph →
→ investigated in trials for	Bevacizumabmonoclonal antibody 1 trials (0 active) · roll-up of the cancer and its descendants	—	—	PEComa	1	Observed	clinicaltrials	graph →
→ investigated in trials for	Celecoxibsmall molecule 1 trials (0 active) · roll-up of the cancer and its descendants	—	—	PEComa	1	Observed	clinicaltrials	graph →
→ investigated in trials for	Cetuximabmonoclonal antibody 1 trials (0 active) · roll-up of the cancer and its descendants	—	—	PEComa	1	Observed	clinicaltrials	graph →
→ investigated in trials for	Dactolisibsmall molecule 1 trials (0 active) · roll-up of the cancer and its descendants	—	—	PEComa	1	Observed	clinicaltrials	graph →
→ investigated in trials for	Doxorubicinsmall molecule 1 trials (0 active) · roll-up of the cancer and its descendants	—	—	PEComa	1	Observed	clinicaltrials	graph →
→ investigated in trials for	Elacestrantsmall molecule 1 trials (1 active) · roll-up of the cancer and its descendants	—	—	PEComa	1	Observed	clinicaltrials	graph →
→ investigated in trials for	Ifosfamidesmall molecule 1 trials (0 active) · roll-up of the cancer and its descendants	—	—	PEComa	1	Observed	clinicaltrials	graph →
→ investigated in trials for	Imatinibsmall molecule 1 trials (0 active) · roll-up of the cancer and its descendants	—	—	PEComa	1	Observed	clinicaltrials	graph →
→ investigated in trials for	Ipilimumabmonoclonal antibody 1 trials (1 active) · roll-up of the cancer and its descendants	—	—	PEComa	1	Observed	clinicaltrials	graph →
→ investigated in trials for	Letrozolesmall molecule 1 trials (0 active) · roll-up of the cancer and its descendants	—	—	PEComa	1	Observed	clinicaltrials	graph →
→ investigated in trials for	Nintedanibsmall molecule 1 trials (0 active) · roll-up of the cancer and its descendants	—	—	PEComa	1	Observed	clinicaltrials	graph →
→ investigated in trials for	Pazopanibsmall molecule 1 trials (0 active) · roll-up of the cancer and its descendants	—	—	PEComa	1	Observed	clinicaltrials	graph →
→ investigated in trials for	Temsirolimussmall molecule 1 trials (0 active) · roll-up of the cancer and its descendants	—	—	PEComa	1	Observed	clinicaltrials	graph →
→ investigated in trials for	Valproic Acidsmall molecule 1 trials (0 active) · roll-up of the cancer and its descendants	—	—	PEComa	1	Observed	clinicaltrials	graph →

PEComa studied in …STUDIED_INderived10 of 62show all (up to 200)
→ studied in	NCT00001465recruiting Study of the Disease Process of Lymphangioleiomyomatosis · condition mapped ONTOLOGY_EXACT · 62 trials mapped (17 active)	—	—	Lymphangioleiomyomatosis	1	Observed	clinicaltrials	graph →
→ studied in	NCT05252585Phase 4 · active not recruiting A Phase IV Study of Safety and Efficacy of Everolimus in Taiwanese Patients With Tuberous Sclerosis Complex Who Have Renal Angiomyolipoma (TSC-AML) · condition mapped ALIAS · 62 trials mapped (17 active)	—	—	Kidney Angiomyolipoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT01484236recruiting National Lymphangioleiomyomatosis Registry, France · condition mapped ONTOLOGY_EXACT · 62 trials mapped (17 active)	—	—	Lymphangioleiomyomatosis	1	Observed	clinicaltrials	graph →
→ studied in	NCT01799538Phase 1/Phase 2 · recruiting Nebulized or Inhaled Albuterol for Lymphangioleiomyomatosis · condition mapped ONTOLOGY_EXACT · 62 trials mapped (17 active)	—	—	Lymphangioleiomyomatosis	1	Observed	clinicaltrials	graph →
→ studied in	NCT05676099recruiting TSC Biosample Repository and Natural History Database · condition mapped ONTOLOGY_EXACT · 62 trials mapped (17 active)	—	—	Lymphangioleiomyomatosis	1	Observed	clinicaltrials	graph →
→ studied in	NCT02180867Phase 2/Phase 3 · completed Radiation Therapy With or Without Combination Chemotherapy or Pazopanib Before Surgery in Treating Patients With Newly Diagnosed Non-rhabdomyosarcoma Soft Tissue Sarcomas That Can Be Removed by Surgery · condition mapped ONTOLOGY_EXACT · 62 trials mapped (17 active)	—	—	PEComa	1	Observed	clinicaltrials	graph →
→ studied in	NCT02834013Phase 2 · active not recruiting Nivolumab and Ipilimumab in Treating Patients With Rare Tumors · condition mapped ONTOLOGY_EXACT · 62 trials mapped (17 active)	—	—	PEComa	1	Observed	clinicaltrials	graph →
→ studied in	NCT07467772Phase 2 · recruiting Ph 2 Elacestrant in ER Positive Uterine Sarcomas · condition mapped ALIAS · 62 trials mapped (17 active)	—	—	PEComa	1	Observed	clinicaltrials	graph →
→ studied in	NCT01552434Phase 1 · terminated Bevacizumab and Temsirolimus Alone or in Combination With Valproic Acid or Cetuximab in Treating Patients With Advanced or Metastatic Malignancy or Other Benign Disease · condition mapped ONTOLOGY_EXACT · 62 trials mapped (17 active)	—	—	Lymphangioleiomyomatosis	1	Observed	clinicaltrials	graph →
→ studied in	NCT06453642NA · active not recruiting Evaluation of a Simple-Prep Controlled Embolic · condition mapped ALIAS · 62 trials mapped (17 active)	—	—	Kidney Angiomyolipoma	1	Observed	clinicaltrials	graph →

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