Mycosis Fungoides and Sezary Syndrome

hematologic malignancy

Identifier: CI-CAN-00008076
Entity page: /cancer/mycosis-fungoides-and-sezary-syndrome ↗
Edges: 200

Neighbours: 19 drugs10 trials
Drawn: 29 of 29 neighbours (cap 60); table lists every fetched edge

Accepted: cancer:<slug>, gene:<symbol>, variant:<slug>, drug:<slug>, trial:<NCT id>, or a bare CI id. Find slugs with search.

Most connectedLung Non-Small Cell Carcinoma 3,149 Malignant Colorectal Neoplasm 1,866 ABL1 298 EGFR 276 Imatinib 450 Dasatinib 321

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Relationship	Neighbour	Direction	Evidence level	Cancer context	Support	Claim	Source	Expand
Mycosis Fungoides and Sezary Syndrome approved for …APPROVED_FORderived9 of 9
← approved for	Cyclophosphamidesmall molecule FDA (US) · approved · 2023-09-12 · mycosis fungoides (advanced disease)	—	approved	Mycosis Fungoides	1	Regulatory	openfda	graph →
← approved for	Methotrexatesmall molecule

Mycosis Fungoides and Sezary Syndrome investigated in trials for …INVESTIGATED_IN_TRIALSderived15 of 43show all (up to 200)
→ investigated in trials for	Mogamulizumabmonoclonal antibody 10 trials (4 active) · roll-up of the cancer and its descendants	—	—	Mycosis Fungoides and Sezary Syndrome	10	Observed	clinicaltrials	graph →
→ investigated in trials for	Brentuximab Vedotinadc 9 trials (4 active) · roll-up of the cancer and its descendants	—	—	Mycosis Fungoides and Sezary Syndrome	9	Observed	clinicaltrials	graph →
→ investigated in trials for	Pembrolizumabmonoclonal antibody 7 trials (3 active) · roll-up of the cancer and its descendants	—	—	Mycosis Fungoides and Sezary Syndrome	7	Observed	clinicaltrials	graph →
→ investigated in trials for	Mechlorethaminesmall molecule 6 trials (0 active) · roll-up of the cancer and its descendants	—	—	Mycosis Fungoides and Sezary Syndrome	6	Observed	clinicaltrials	graph →
→ investigated in trials for	Cyclophosphamidesmall molecule 5 trials (3 active) · roll-up of the cancer and its descendants	—	—	Mycosis Fungoides and Sezary Syndrome	5	Observed	clinicaltrials	graph →
→ investigated in trials for	Fludarabinesmall molecule 5 trials (2 active) · roll-up of the cancer and its descendants	—	—	Mycosis Fungoides and Sezary Syndrome	5	Observed	clinicaltrials	graph →
→ investigated in trials for	Nivolumabmonoclonal antibody 5 trials (3 active) · roll-up of the cancer and its descendants	—	—	Mycosis Fungoides and Sezary Syndrome	5	Observed	clinicaltrials	graph →
→ investigated in trials for	Romidepsinother 5 trials (1 active) · roll-up of the cancer and its descendants	—	—	Mycosis Fungoides and Sezary Syndrome	5	Observed	clinicaltrials	graph →
→ investigated in trials for	Cemiplimabmonoclonal antibody 3 trials (2 active) · roll-up of the cancer and its descendants	—	—	Mycosis Fungoides and Sezary Syndrome	3	Observed	clinicaltrials	graph →
→ investigated in trials for	Lenalidomidesmall molecule 3 trials (1 active) · roll-up of the cancer and its descendants	—	—	Mycosis Fungoides and Sezary Syndrome	3	Observed	clinicaltrials	graph →
→ investigated in trials for	Vorinostatsmall molecule 3 trials (0 active) · roll-up of the cancer and its descendants	—	—	Mycosis Fungoides and Sezary Syndrome	3	Observed	clinicaltrials	graph →
→ investigated in trials for	Alemtuzumabmonoclonal antibody 2 trials (0 active) · roll-up of the cancer and its descendants	—	—	Mycosis Fungoides and Sezary Syndrome	2	Observed	clinicaltrials	graph →
→ investigated in trials for	Bendamustinesmall molecule 2 trials (1 active) · roll-up of the cancer and its descendants	—	—	Mycosis Fungoides and Sezary Syndrome	2	Observed	clinicaltrials	graph →
→ investigated in trials for	Bexarotenesmall molecule 2 trials (0 active) · roll-up of the cancer and its descendants	—	—	Mycosis Fungoides and Sezary Syndrome	2	Observed	clinicaltrials	graph →
→ investigated in trials for	Dasatinibsmall molecule 2 trials (0 active) · roll-up of the cancer and its descendants	—	—	Mycosis Fungoides and Sezary Syndrome	2	Observed	clinicaltrials	graph →

Mycosis Fungoides and Sezary Syndrome investigated in trials for …INVESTIGATED_IN_TRIALSderived15 of 43show all (up to 200)

→ investigated in trials for

Mogamulizumabmonoclonal antibody

10 trials (4 active) · roll-up of the cancer and its descendants

—

Mycosis Fungoides and Sezary Syndrome

Observed

Mycosis Fungoides and Sezary Syndrome studied in …STUDIED_INderived10 of 148show all (up to 200)
→ studied in	NCT05944562Phase 1 · active not recruiting Tulmimetostat (DZR123) in Patients With Mycosis Fungoides and Sézary Syndrome · condition mapped ONTOLOGY_EXACT · 148 trials mapped (47 active)	—	—	Mycosis Fungoides	1	Observed	clinicaltrials	graph →
→ studied in	NCT07003100recruiting A Prospective, US-based Study Assessing Mogamulizumab-associated Rash in Patients Diagnosed With Mycosis Fungoides or Sezary Syndrome and Treated With Standard of Care Mogamulizumab · condition mapped CURATED_BROADER · 148 trials mapped (47 active)	—	—	Mycosis Fungoides and Sezary Syndrome	1	Observed	clinicaltrials	graph →
→ studied in	NCT03380026Phase 2 · completed Mechlorethamine Induced Contact Dermatitis Avoidance Study · condition mapped ONTOLOGY_EXACT · 148 trials mapped (47 active)	—	—	Mycosis Fungoides	1	Observed	clinicaltrials	graph →
→ studied in	NCT04930653Phase 2 · recruiting Extracorporeal Photopheresis and Mogamulizumab for the Treatment of Erythrodermic Cutaneous T Cell Lymphoma · condition mapped CURATED_BROADER · 148 trials mapped (47 active)	—	—	Mycosis Fungoides and Sezary Syndrome	1	Observed	clinicaltrials	graph →
→ studied in	NCT04904146recruiting Predictive and Prognostic Biomarkers in Patients With Mycosis Fungoides and Sézary Syndrome. · condition mapped ONTOLOGY_EXACT · 148 trials mapped (47 active)	—	—	Mycosis Fungoides	1	Observed	clinicaltrials	graph →
→ studied in	NCT07781449Phase 2 · not yet recruiting Topical JAK-Inhibition of Early-Stage CTCL · condition mapped ONTOLOGY_EXACT · 148 trials mapped (47 active)	—	—	Mycosis Fungoides	1	Observed	clinicaltrials	graph →
→ studied in	NCT07055477Phase 1 · recruiting A Phase I Trial Anti-CC Chemokine Receptor 4 Chimeric Antigen Receptor T Cells (CCR4 CAR T Cells) for CCR4 Expressing T-cell Malignancies Including Peripheral T-cell Non-Hodgkin Lymphoma (PTCL) and Cutaneous T-cell Non-Hodgkin Lymphoma (CTCL) · condition mapped ONTOLOGY_EXACT · 148 trials mapped (47 active)	—	—	Mycosis Fungoides	1	Observed	clinicaltrials	graph →
→ studied in	NCT02702310suspended Low-Dose Total Skin Electron Therapy in Treating Patients With Refractory or Relapsed Stage IB-IIIA Mycosis Fungoides · condition mapped CURATED_BROADER · 148 trials mapped (47 active)	—	—	Mycosis Fungoides	1	Observed	clinicaltrials	graph →
→ studied in	NCT02978625Phase 2 · active not recruiting Talimogene Laherparepvec and Nivolumab in Treating Patients With Refractory Lymphomas or Advanced or Refractory Non-melanoma Skin Cancers · condition mapped CURATED_BROADER · 148 trials mapped (47 active)	—	—	Mycosis Fungoides	1	Observed	clinicaltrials	graph →
→ studied in	NCT03011814Phase 1/Phase 2 · recruiting Durvalumab With or Without Lenalidomide in Treating Patients With Relapsed or Refractory Cutaneous or Peripheral T Cell Lymphoma · condition mapped ONTOLOGY_EXACT · 148 trials mapped (47 active)	—	—	Folliculotropic Mycosis Fungoides	1	Observed	clinicaltrials	graph →

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