Mucosal Melanoma

histology

Identifier: CI-CAN-00003356
Entity page: /cancer/mucosal-melanoma ↗
Edges: 112

Neighbours: 2 genes3 variants17 drugs10 trials
Drawn: 32 of 32 neighbours (cap 60); table lists every fetched edge

Accepted: cancer:<slug>, gene:<symbol>, variant:<slug>, drug:<slug>, trial:<NCT id>, or a bare CI id. Find slugs with search.

Most connectedLung Non-Small Cell Carcinoma 3,149 Malignant Colorectal Neoplasm 1,866 ABL1 298 EGFR 276 Imatinib 450 Dasatinib 321

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Source-native edges first (aggregated per neighbour, direction, evidence level and source), then derived registry links. Up to 15 per relationship (10 trials); “show all” raises one group to 200.

Relationship	Neighbour	Direction	Evidence level	Cancer context	Support	Claim	Source	Expand
Mucosal Melanoma predicts response to …PREDICTS_RESPONSE_TO3 of 3
in context · predicts response to	KIT Amplificationamplification → predicts response to Imatinib	resistance	B	Mucosal Melanoma	1	Curated	civic	graph →
in context · predicts response to	NRAS Q61L

Mucosal Melanoma associated with …ASSOCIATED_WITH3 of 3
← associated with	KIT	supports	B	Mucosal Melanoma	1	Curated	civic	graph →
← associated with	NRAS	supports	C	Mucosal Melanoma	1	Curated	civic	graph →
← associated with	KIT	supports	C	Mucosal Melanoma	1	Curated	civic	graph →

Mucosal Melanoma associated with …ASSOCIATED_WITH3 of 3

← associated with

KIT

supports

Mucosal Melanoma

Curated

Mucosal Melanoma investigated for …INVESTIGATED_FOR3 of 3
← investigated for	Imatinibsmall_molecule	supports	B	Mucosal Melanoma	1	Curated	civic	graph →
← investigated for	Belvarafenibsmall_molecule	supports	C	Mucosal Melanoma	1	Curated	civic	graph →
← investigated for	Imatinibsmall_molecule	supports	C	Mucosal Melanoma	1	Curated	civic	graph →

Mucosal Melanoma investigated in trials for …INVESTIGATED_IN_TRIALSderived15 of 29show all (up to 200)
→ investigated in trials for	Nivolumabmonoclonal antibody 16 trials (10 active) · roll-up of the cancer and its descendants	—	—	Mucosal Melanoma	16	Observed	clinicaltrials	graph →
→ investigated in trials for	Ipilimumabmonoclonal antibody 13 trials (6 active) · roll-up of the cancer and its descendants	—	—	Mucosal Melanoma	13	Observed	clinicaltrials	graph →
→ investigated in trials for	Pembrolizumabmonoclonal antibody 12 trials (6 active) · roll-up of the cancer and its descendants	—	—	Mucosal Melanoma	12	Observed	clinicaltrials	graph →
→ investigated in trials for	Aldesleukinother 2 trials (0 active) · roll-up of the cancer and its descendants	—	—	Mucosal Melanoma	2	Observed	clinicaltrials	graph →
→ investigated in trials for	Axitinibsmall molecule 2 trials (1 active) · roll-up of the cancer and its descendants	—	—	Mucosal Melanoma	2	Observed	clinicaltrials	graph →
→ investigated in trials for	Nilotinibsmall molecule 2 trials (0 active) · roll-up of the cancer and its descendants	—	—	Mucosal Melanoma	2	Observed	clinicaltrials	graph →
→ investigated in trials for	Toripalimabmonoclonal antibody 2 trials (0 active) · roll-up of the cancer and its descendants	—	—	Mucosal Melanoma	2	Observed	clinicaltrials	graph →
→ investigated in trials for	Bevacizumabmonoclonal antibody 1 trials (0 active) · roll-up of the cancer and its descendants	—	—	Mucosal Melanoma	1	Observed	clinicaltrials	graph →
→ investigated in trials for	Binimetinibsmall molecule 1 trials (1 active) · roll-up of the cancer and its descendants	—	—	Mucosal Melanoma	1	Observed	clinicaltrials	graph →
→ investigated in trials for	Cabozantinibsmall molecule 1 trials (1 active) · roll-up of the cancer and its descendants	—	—	Mucosal Melanoma	1	Observed	clinicaltrials	graph →
→ investigated in trials for	Carboplatinsmall molecule 1 trials (0 active) · roll-up of the cancer and its descendants	—	—	Mucosal Melanoma	1	Observed	clinicaltrials	graph →
→ investigated in trials for	Cisplatinsmall molecule 1 trials (1 active) · roll-up of the cancer and its descendants	—	—	Mucosal Melanoma	1	Observed	clinicaltrials	graph →
→ investigated in trials for	Cyclophosphamidesmall molecule 1 trials (0 active) · roll-up of the cancer and its descendants	—	—	Mucosal Melanoma	1	Observed	clinicaltrials	graph →
→ investigated in trials for	Dinaciclibsmall molecule 1 trials (1 active) · roll-up of the cancer and its descendants	—	—	Mucosal Melanoma	1	Observed	clinicaltrials	graph →
→ investigated in trials for	Encorafenibsmall molecule 1 trials (1 active) · roll-up of the cancer and its descendants	—	—	Mucosal Melanoma	1	Observed	clinicaltrials	graph →

Mucosal Melanoma studied in …STUDIED_INderived10 of 74show all (up to 200)
→ studied in	NCT07576725Phase 2 · not yet recruiting Low Dose, Reduced Frequency Nivolumab for the Treatment of Unresectable or Metastatic Cancer, AFFORD IO Trial · condition mapped CURATED_BROADER · 74 trials mapped (29 active)	—	—	Mucosal Melanoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT04462406Phase 2 · active not recruiting Using Biomarkers to Help Guide Safe Immunotherapy Discontinuation in Patients With Unresectable Stage IIIB-IV Melanoma, The PET-Stop Trial · condition mapped CURATED_BROADER · 74 trials mapped (29 active)	—	—	Mucosal Melanoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT04511013Phase 2 · recruiting A Study to Compare the Administration of Encorafenib + Binimetinib + Nivolumab Versus Ipilimumab + Nivolumab in BRAF-V600 Mutant Melanoma With Brain Metastases · condition mapped CURATED_BROADER · 74 trials mapped (29 active)	—	—	Mucosal Melanoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT00937937Phase 2 · active not recruiting Dinaciclib in Treating Patients With Stage IV Melanoma · condition mapped ONTOLOGY_EXACT · 74 trials mapped (29 active)	—	—	Mucosal Melanoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT05546827Phase 2 · recruiting Preoperative Radiotherapy and Immunotherapy for Sinonasal and Anorectal Mucosal Melanoma · condition mapped ALIAS · 74 trials mapped (29 active)	—	—	Sinonasal Mucosal Melanoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT07400302Phase 2 · recruiting Sintilimab Combined With Chemotherapy for Adjuvant Treatment of Mucosal Melanoma After Surgery · condition mapped ONTOLOGY_EXACT · 74 trials mapped (29 active)	—	—	Mucosal Melanoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT07076550Phase 1 · terminated A Phase 1-1b Study to Evaluate the Safety, Efficacy and Dosimetry of Study Drug A9-3408 in Subjects With Metastatic Melanoma · condition mapped ONTOLOGY_EXACT · 74 trials mapped (29 active)	—	—	Mucosal Melanoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT02506153Phase 3 · active not recruiting Physician/Patient Choice of Either High-Dose Recombinant Interferon Alfa-2B or Ipilimumab, Versus Pembrolizumab in Treating Patients With Stage III-IV High Risk Melanoma That Has Been Removed by Surgery · condition mapped CURATED_BROADER · 74 trials mapped (29 active)	—	—	Mucosal Melanoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT04318717Phase 2 · recruiting Pembrolizumab and Hypofractionated Radiation Therapy for the Treatment of Mucosal Melanoma · condition mapped ALIAS · 74 trials mapped (29 active)	—	—	Head and Neck Mucosal Melanoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT03025256Phase 1 · active not recruiting Intravenous and Intrathecal Nivolumab in Treating Patients With Leptomeningeal Disease · condition mapped CURATED_BROADER · 74 trials mapped (29 active)	—	—	Mucosal Melanoma	1	Observed	clinicaltrials	graph →

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