Malignant Peripheral Nervous System Neoplasm

subtype

Identifier: CI-CAN-00001163
Entity page: /cancer/malignant-peripheral-nervous-system-neoplasm ↗
Edges: 92

Neighbours: 15 drugs10 trials
Drawn: 25 of 25 neighbours (cap 60); table lists every fetched edge

Accepted: cancer:<slug>, gene:<symbol>, variant:<slug>, drug:<slug>, trial:<NCT id>, or a bare CI id. Find slugs with search.

Most connectedLung Non-Small Cell Carcinoma 3,147 Malignant Colorectal Neoplasm 1,866 ABL1 298 EGFR 276 Imatinib 450 Dasatinib 321

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Relationship	Neighbour	Direction	Evidence level	Cancer context	Support	Claim	Source	Expand
Malignant Peripheral Nervous System Neoplasm investigated in trials for …INVESTIGATED_IN_TRIALSderived15 of 32show all (up to 200)
→ investigated in trials for	Doxorubicinsmall molecule 7 trials (2 active) · roll-up of the cancer and its descendants	—	—	Malignant Peripheral Nervous System Neoplasm	7	Observed	clinicaltrials	graph →
→ investigated in trials for

Malignant Peripheral Nervous System Neoplasm studied in …STUDIED_INderived10 of 60show all (up to 200)
→ studied in	NCT00924196active not recruiting Natural History Study of Patients With Neurofibromatosis Type I · condition mapped ONTOLOGY_EXACT · 60 trials mapped (24 active)	—	—	Malignant Peripheral Nerve Sheath Tumor	1	Observed	clinicaltrials	graph →
→ studied in	NCT04222413Phase 1 · recruiting Metarrestin (ML-246) in Subjects With Metastatic Solid Tumors · condition mapped ONTOLOGY_EXACT · 60 trials mapped (24 active)	—	—	Malignant Peripheral Nerve Sheath Tumor	1	Observed	clinicaltrials	graph →
→ studied in	NCT07298083recruiting DoD Award NF230020 Identification of Metabolic Markers and Statistical Prediction of MPNST for Rapid Diagnosis and Assessment of Surgical Margins · condition mapped ALIAS · 60 trials mapped (24 active)	—	—	Malignant Peripheral Nerve Sheath Tumor	1	Observed	clinicaltrials	graph →
→ studied in	NCT05245500Phase 1 · recruiting Phase 1 Study of MRTX1719 in Solid Tumors With MTAP Deletion · condition mapped ONTOLOGY_EXACT · 60 trials mapped (24 active)	—	—	Malignant Peripheral Nerve Sheath Tumor	1	Observed	clinicaltrials	graph →
→ studied in	NCT06515860enrolling by invitation Neurofibromatosis Type 1 Tumor Early Detection Study · condition mapped ONTOLOGY_EXACT · 60 trials mapped (24 active)	—	—	Malignant Peripheral Nerve Sheath Tumor	1	Observed	clinicaltrials	graph →
→ studied in	NCT05253131Phase 2 · recruiting Trial of Selumetinib and Bromodomain Inhibitor With Durvalumab for Sarcomas · condition mapped ALIAS · 60 trials mapped (24 active)	—	—	Malignant Peripheral Nerve Sheath Tumor	1	Observed	clinicaltrials	graph →
→ studied in	NCT05642455Phase 1/Phase 2 · recruiting SPEARHEAD-3 Pediatric Study · condition mapped ONTOLOGY_EXACT · 60 trials mapped (24 active)	—	—	Malignant Peripheral Nerve Sheath Tumor	1	Observed	clinicaltrials	graph →
→ studied in	NCT07549022Phase 1/Phase 2 · recruiting Safety and Efficacy of BMS-986504 in Unresectable Malignant Peripheral Nerve Sheath Tumor · condition mapped ONTOLOGY_EXACT · 60 trials mapped (24 active)	—	—	Malignant Peripheral Nerve Sheath Tumor	1	Observed	clinicaltrials	graph →
→ studied in	NCT02211768Phase 1 · completed Transformation of Plexiform Neurofibromas to Malignant Peripheral Nerve Sheath Tumors in Neurofibromatosis Type 1 · condition mapped ALIAS · 60 trials mapped (24 active)	—	—	Malignant Peripheral Nerve Sheath Tumor	1	Observed	clinicaltrials	graph →
→ studied in	NCT07743554Phase 2 · not yet recruiting Combination of Avutometinib and Defactinib for Treatment of Relapsed, Refractory, Metastatic, or Unresectable Malignant Peripheral Nerve Sheath Tumor · condition mapped ALIAS · 60 trials mapped (24 active)	—	—	Malignant Peripheral Nerve Sheath Tumor	1	Observed	clinicaltrials	graph →

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