Malignant Oropharyngeal Neoplasm

Observed

→ investigated in trials for

Cetuximabmonoclonal antibody

27 trials (4 active) · roll-up of the cancer and its descendants

—

Observed

→ investigated in trials for

Carboplatinsmall molecule

25 trials (13 active) · roll-up of the cancer and its descendants

—

Observed

→ investigated in trials for

Pembrolizumabmonoclonal antibody

20 trials (14 active) · roll-up of the cancer and its descendants

—

Observed

→ investigated in trials for

Erlotinib Hydrochloridesmall molecule

14 trials (1 active) · roll-up of the cancer and its descendants

—

Observed

→ investigated in trials for

Paclitaxelsmall molecule

14 trials (6 active) · roll-up of the cancer and its descendants

—

Observed

→ investigated in trials for

Docetaxelsmall molecule

12 trials (3 active) · roll-up of the cancer and its descendants

—

Observed

→ investigated in trials for

Durvalumabmonoclonal antibody

9 trials (3 active) · roll-up of the cancer and its descendants

—

Observed

→ investigated in trials for

Fluorouracilsmall molecule

9 trials (3 active) · roll-up of the cancer and its descendants

—

Observed

→ investigated in trials for

Nivolumabmonoclonal antibody

9 trials (3 active) · roll-up of the cancer and its descendants

—

Observed

→ investigated in trials for

Nab-paclitaxel

6 trials (4 active) · roll-up of the cancer and its descendants

—

Observed

→ investigated in trials for

Bevacizumabmonoclonal antibody

5 trials (1 active) · roll-up of the cancer and its descendants

—

Observed

→ investigated in trials for

Cyclophosphamidesmall molecule

5 trials (1 active) · roll-up of the cancer and its descendants

—

Observed

→ investigated in trials for

Aldesleukinother

4 trials (2 active) · roll-up of the cancer and its descendants

—

Observed

→ investigated in trials for

Cemiplimabmonoclonal antibody

4 trials (2 active) · roll-up of the cancer and its descendants

—

Observed

→ investigated in trials for

Hydroxyureasmall molecule

4 trials (0 active) · roll-up of the cancer and its descendants

—

Observed

→ investigated in trials for

Vorinostatsmall molecule

4 trials (0 active) · roll-up of the cancer and its descendants

—

Observed

→ investigated in trials for

Capecitabinesmall molecule

3 trials (0 active) · roll-up of the cancer and its descendants

—

Observed

→ investigated in trials for

Dexamethasonesmall molecule

3 trials (0 active) · roll-up of the cancer and its descendants

—

Observed

→ investigated in trials for

Fludarabinesmall molecule

3 trials (1 active) · roll-up of the cancer and its descendants

—

Observed

→ investigated in trials for

Ipilimumabmonoclonal antibody

3 trials (1 active) · roll-up of the cancer and its descendants

—

Observed

→ investigated in trials for

Lapatinibsmall molecule

3 trials (0 active) · roll-up of the cancer and its descendants

—

Observed

→ investigated in trials for

Sorafenib Tosylatesmall molecule

3 trials (0 active) · roll-up of the cancer and its descendants

—

Observed

→ investigated in trials for

Tislelizumabmonoclonal antibody

3 trials (3 active) · roll-up of the cancer and its descendants

—

Observed

→ investigated in trials for

Tremelimumabmonoclonal antibody

3 trials (1 active) · roll-up of the cancer and its descendants

—

Observed

→ investigated in trials for

Alpelisibsmall molecule

2 trials (0 active) · roll-up of the cancer and its descendants

—

Observed

→ investigated in trials for

Atezolizumabmonoclonal antibody

2 trials (1 active) · roll-up of the cancer and its descendants

—

Observed

→ investigated in trials for

Buparlisibsmall molecule

2 trials (0 active) · roll-up of the cancer and its descendants

—

Observed

→ investigated in trials for

Cabozantinibsmall molecule

2 trials (2 active) · roll-up of the cancer and its descendants

—

Observed

→ investigated in trials for

Celecoxibsmall molecule

2 trials (1 active) · roll-up of the cancer and its descendants

—

Observed

→ investigated in trials for

Chemotherapy

2 trials (0 active) · roll-up of the cancer and its descendants

—

Observed

→ investigated in trials for

Everolimussmall molecule

2 trials (0 active) · roll-up of the cancer and its descendants

—

Observed

→ investigated in trials for

Gefitinibsmall molecule

2 trials (0 active) · roll-up of the cancer and its descendants

—

Observed

→ investigated in trials for

Ipatasertibsmall molecule

2 trials (2 active) · roll-up of the cancer and its descendants

—

Observed

→ investigated in trials for

Irinotecansmall molecule

2 trials (0 active) · roll-up of the cancer and its descendants

—

Observed

→ investigated in trials for

Prednisonesmall molecule

2 trials (2 active) · roll-up of the cancer and its descendants

—

Observed

→ investigated in trials for

Sunitinibsmall molecule

2 trials (0 active) · roll-up of the cancer and its descendants

—

Observed

→ investigated in trials for

Toripalimabmonoclonal antibody

2 trials (2 active) · roll-up of the cancer and its descendants

—

Observed

→ investigated in trials for

Alvespimycinsmall molecule

1 trials (0 active) · roll-up of the cancer and its descendants

—

Observed

Anti-EGFR Monoclonal Antibody

→ investigated in trials for

1 trials (0 active) · roll-up of the cancer and its descendants

—

Observed

→ investigated in trials for

Berzosertibsmall molecule

1 trials (1 active) · roll-up of the cancer and its descendants

—

Observed

→ investigated in trials for

Bortezomibsmall molecule

1 trials (0 active) · roll-up of the cancer and its descendants

—

Observed

→ investigated in trials for

Camonsertibsmall molecule

1 trials (1 active) · roll-up of the cancer and its descendants

—

Observed

→ investigated in trials for

Cediranibsmall molecule

1 trials (0 active) · roll-up of the cancer and its descendants

—

Observed

→ investigated in trials for

Dasatinibsmall molecule

1 trials (0 active) · roll-up of the cancer and its descendants

—

Observed

→ investigated in trials for

Elimusertibsmall molecule

1 trials (1 active) · roll-up of the cancer and its descendants

—

Observed

→ investigated in trials for

Filgrastimother

1 trials (0 active) · roll-up of the cancer and its descendants

—

Observed

→ investigated in trials for

Ganetespibsmall molecule

1 trials (0 active) · roll-up of the cancer and its descendants

—

Observed

→ investigated in trials for

Immunotherapy

1 trials (0 active) · roll-up of the cancer and its descendants

—

Observed

→ investigated in trials for

Infigratinibsmall molecule

1 trials (0 active) · roll-up of the cancer and its descendants

—

Observed

→ investigated in trials for

Lenalidomidesmall molecule

1 trials (0 active) · roll-up of the cancer and its descendants

—

Observed

→ investigated in trials for

Metforminsmall molecule

1 trials (0 active) · roll-up of the cancer and its descendants

—

Observed

→ investigated in trials for

Methotrexatesmall molecule

1 trials (1 active) · roll-up of the cancer and its descendants

—

Observed

→ investigated in trials for

Nimotuzumabmonoclonal antibody

1 trials (0 active) · roll-up of the cancer and its descendants

—

Observed

→ investigated in trials for

Nogapendekin Alfa Inbakiceptother

1 trials (1 active) · roll-up of the cancer and its descendants

—

Observed

→ investigated in trials for

Onalespibsmall molecule

1 trials (0 active) · roll-up of the cancer and its descendants

—

Observed

→ investigated in trials for

Porfimer

1 trials (0 active) · roll-up of the cancer and its descendants

—

Observed

→ investigated in trials for

Romidepsinother

1 trials (0 active) · roll-up of the cancer and its descendants

—

Observed

→ investigated in trials for

Sacituzumab Govitecanadc

1 trials (1 active) · roll-up of the cancer and its descendants

—

Observed

→ investigated in trials for

Sintilimabmonoclonal antibody

1 trials (1 active) · roll-up of the cancer and its descendants

—

Observed

→ investigated in trials for

Sorafenibsmall molecule

1 trials (1 active) · roll-up of the cancer and its descendants

—

Observed

→ investigated in trials for

Temoporfinsmall molecule

1 trials (0 active) · roll-up of the cancer and its descendants

—

Observed

→ investigated in trials for

Temsirolimussmall molecule

1 trials (0 active) · roll-up of the cancer and its descendants

—

Observed

→ investigated in trials for

Tretinoinsmall molecule

1 trials (1 active) · roll-up of the cancer and its descendants

—

Observed

→ investigated in trials for

Valproic Acidsmall molecule

1 trials (0 active) · roll-up of the cancer and its descendants

—

Observed

→ investigated in trials for

Veliparibsmall molecule

1 trials (0 active) · roll-up of the cancer and its descendants

—

Observed

Malignant Oropharyngeal Neoplasm studied in …STUDIED_INderived10 of 461show all (up to 200)
→ studied in	NCT06309225NA · recruiting Dose Adjusted Chemoradiotherapy in HPV-Associated Oropharynx Cancer of the Elderly · condition mapped ALIAS · 461 trials mapped (180 active)	—	—	Malignant Oropharyngeal Neoplasm	1	Observed	clinicaltrials	graph →
→ studied in	NCT06589804Phase 3 · recruiting Testing the Addition of Anti-Cancer Drug, Cetuximab, to Standard of Care Treatment (Pembrolizumab) for Returning or Spreading Head and Neck Cancer After Previous Treatment · condition mapped CURATED_BROADER · 461 trials mapped (180 active)	—	—	Oropharyngeal Squamous Cell Carcinoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT07667400Phase 1/Phase 2 · not yet recruiting Docetaxel and SX-682 in Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma, Salivary Gland Carcinoma, and Advanced Prostate Cancer · condition mapped ONTOLOGY_EXACT · 461 trials mapped (180 active)	—	—	Oropharyngeal Squamous Cell Carcinoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT03644563active not recruiting Men and Women Offering Understanding of Throat HPV · condition mapped CURATED_EXACT · 461 trials mapped (180 active)	—	—	Malignant Oropharyngeal Neoplasm	1	Observed	clinicaltrials	graph →
→ studied in	NCT05136196Phase 2 · recruiting BiCaZO: A Study Combining Two Immunotherapies (Cabozantinib and Nivolumab) to Treat Patients With Advanced Melanoma or Squamous Cell Head and Neck Cancer, an immunoMATCH Pilot Study · condition mapped CURATED_BROADER · 461 trials mapped (180 active)	—	—	Oropharyngeal Squamous Cell Carcinoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT06980038Phase 2 · recruiting Testing Whether Cemiplimab (REGN2810) Plus CDX-1140 Given Prior to Surgery Are Better Than Cemiplimab (REGN2810) Alone in Patients With Stage III-IV Head and Neck Cancer · condition mapped ONTOLOGY_EXACT · 461 trials mapped (180 active)	—	—	Oropharyngeal Squamous Cell Carcinoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT05814549active not recruiting A Study Using Human Papillomavirus (HPV) DNA Testing to Detect HPV-Related Oropharyngeal Cancer (OPC) · condition mapped CURATED_EXACT · 461 trials mapped (180 active)	—	—	Malignant Oropharyngeal Neoplasm	1	Observed	clinicaltrials	graph →
→ studied in	NCT06305676recruiting Biomarker Approach to Screening for the Early Detection of HPV-related Oropharyngeal Cancer (BASH OPC) · condition mapped CURATED_EXACT · 461 trials mapped (180 active)	—	—	Malignant Oropharyngeal Neoplasm	1	Observed	clinicaltrials	graph →
→ studied in	NCT04671667Phase 2 · recruiting Testing What Happens When an Immunotherapy Drug (Pembrolizumab) is Given by Itself Compared to the Usual Treatment of Chemotherapy With Radiation After Surgery for Recurrent Head and Neck Squamous Cell Carcinoma · condition mapped CURATED_BROADER · 461 trials mapped (180 active)	—	—	Oropharyngeal Squamous Cell Carcinoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT04708470Phase 1/Phase 2 · completed A Phase I/II Study of Combination Immunotherapy for Advanced Cancers Including HPV-Associated Malignancies, Small Bowel, and Colon Cancers · condition mapped CURATED_EXACT · 461 trials mapped (180 active)	—	—	Malignant Oropharyngeal Neoplasm	1	Observed	clinicaltrials	graph →

Malignant Oropharyngeal Neoplasm studied in …STUDIED_INderived10 of 461show all (up to 200)

→ studied in

NCT06309225NA · recruiting

Dose Adjusted Chemoradiotherapy in HPV-Associated Oropharynx Cancer of the Elderly · condition mapped ALIAS · 461 trials mapped (180 active)

—

Observed

→ studied in

NCT06589804Phase 3 · recruiting

Testing the Addition of Anti-Cancer Drug, Cetuximab, to Standard of Care Treatment (Pembrolizumab) for Returning or Spreading Head and Neck Cancer After Previous Treatment · condition mapped CURATED_BROADER · 461 trials mapped (180 active)

—

Observed

→ studied in

NCT07667400Phase 1/Phase 2 · not yet recruiting

Docetaxel and SX-682 in Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma, Salivary Gland Carcinoma, and Advanced Prostate Cancer · condition mapped ONTOLOGY_EXACT · 461 trials mapped (180 active)

—

Observed

→ studied in

NCT03644563active not recruiting

Men and Women Offering Understanding of Throat HPV · condition mapped CURATED_EXACT · 461 trials mapped (180 active)

—

Observed

→ studied in

NCT05136196Phase 2 · recruiting

BiCaZO: A Study Combining Two Immunotherapies (Cabozantinib and Nivolumab) to Treat Patients With Advanced Melanoma or Squamous Cell Head and Neck Cancer, an immunoMATCH Pilot Study · condition mapped CURATED_BROADER · 461 trials mapped (180 active)

—

Observed

→ studied in

NCT06980038Phase 2 · recruiting

Testing Whether Cemiplimab (REGN2810) Plus CDX-1140 Given Prior to Surgery Are Better Than Cemiplimab (REGN2810) Alone in Patients With Stage III-IV Head and Neck Cancer · condition mapped ONTOLOGY_EXACT · 461 trials mapped (180 active)

—

Observed

→ studied in

NCT05814549active not recruiting

A Study Using Human Papillomavirus (HPV) DNA Testing to Detect HPV-Related Oropharyngeal Cancer (OPC) · condition mapped CURATED_EXACT · 461 trials mapped (180 active)

—

Observed

→ studied in

NCT06305676recruiting

Biomarker Approach to Screening for the Early Detection of HPV-related Oropharyngeal Cancer (BASH OPC) · condition mapped CURATED_EXACT · 461 trials mapped (180 active)

—

Observed

→ studied in

NCT04671667Phase 2 · recruiting

Testing What Happens When an Immunotherapy Drug (Pembrolizumab) is Given by Itself Compared to the Usual Treatment of Chemotherapy With Radiation After Surgery for Recurrent Head and Neck Squamous Cell Carcinoma · condition mapped CURATED_BROADER · 461 trials mapped (180 active)

—

Observed

→ studied in

NCT04708470Phase 1/Phase 2 · completed

A Phase I/II Study of Combination Immunotherapy for Advanced Cancers Including HPV-Associated Malignancies, Small Bowel, and Colon Cancers · condition mapped CURATED_EXACT · 461 trials mapped (180 active)

—

Observed