Malignant Oropharyngeal Neoplasm

cancer

Identifier: CI-CAN-00005913
Entity page: /cancer/malignant-oropharyngeal-neoplasm ↗
Edges: 529

Neighbours: 1 genes1 variants15 drugs10 trials
Drawn: 27 of 27 neighbours (cap 60); table lists every fetched edge

Accepted: cancer:<slug>, gene:<symbol>, variant:<slug>, drug:<slug>, trial:<NCT id>, or a bare CI id. Find slugs with search.

Most connectedLung Non-Small Cell Carcinoma 3,149 Malignant Colorectal Neoplasm 1,866 ABL1 298 EGFR 276 Imatinib 450 Dasatinib 321

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Relationship	Neighbour	Direction	Evidence level	Cancer context	Support	Claim	Source	Expand
Malignant Oropharyngeal Neoplasm prognostic in …PROGNOSTIC_IN1 of 1
← prognostic in	CDKN2A p16 Expressionexpression	supports	A	Malignant Oropharyngeal Neoplasm	1	Curated	civic	graph →
Malignant Oropharyngeal Neoplasm associated with …ASSOCIATED_WITH1 of 1
associated with

Malignant Oropharyngeal Neoplasm investigated in trials for …INVESTIGATED_IN_TRIALSderived15 of 66show all (up to 200)
→ investigated in trials for	Cisplatinsmall molecule 70 trials (33 active) · roll-up of the cancer and its descendants	—	—	Malignant Oropharyngeal Neoplasm	70	Observed	clinicaltrials	graph →
→ investigated in trials for	Cetuximabmonoclonal antibody 27 trials (4 active) · roll-up of the cancer and its descendants	—	—	Malignant Oropharyngeal Neoplasm	27	Observed	clinicaltrials	graph →
→ investigated in trials for	Carboplatinsmall molecule 25 trials (13 active) · roll-up of the cancer and its descendants	—	—	Malignant Oropharyngeal Neoplasm	25	Observed	clinicaltrials	graph →
→ investigated in trials for	Pembrolizumabmonoclonal antibody 20 trials (14 active) · roll-up of the cancer and its descendants	—	—	Malignant Oropharyngeal Neoplasm	20	Observed	clinicaltrials	graph →
→ investigated in trials for	Erlotinib Hydrochloridesmall molecule 14 trials (1 active) · roll-up of the cancer and its descendants	—	—	Malignant Oropharyngeal Neoplasm	14	Observed	clinicaltrials	graph →
→ investigated in trials for	Paclitaxelsmall molecule 14 trials (6 active) · roll-up of the cancer and its descendants	—	—	Malignant Oropharyngeal Neoplasm	14	Observed	clinicaltrials	graph →
→ investigated in trials for	Docetaxelsmall molecule 12 trials (3 active) · roll-up of the cancer and its descendants	—	—	Malignant Oropharyngeal Neoplasm	12	Observed	clinicaltrials	graph →
→ investigated in trials for	Durvalumabmonoclonal antibody 9 trials (3 active) · roll-up of the cancer and its descendants	—	—	Malignant Oropharyngeal Neoplasm	9	Observed	clinicaltrials	graph →
→ investigated in trials for	Fluorouracilsmall molecule 9 trials (3 active) · roll-up of the cancer and its descendants	—	—	Malignant Oropharyngeal Neoplasm	9	Observed	clinicaltrials	graph →
→ investigated in trials for	Nivolumabmonoclonal antibody 9 trials (3 active) · roll-up of the cancer and its descendants	—	—	Malignant Oropharyngeal Neoplasm	9	Observed	clinicaltrials	graph →
→ investigated in trials for	Nab-paclitaxel 6 trials (4 active) · roll-up of the cancer and its descendants	—	—	Malignant Oropharyngeal Neoplasm	6	Observed	clinicaltrials	graph →
→ investigated in trials for	Bevacizumabmonoclonal antibody 5 trials (1 active) · roll-up of the cancer and its descendants	—	—	Malignant Oropharyngeal Neoplasm	5	Observed	clinicaltrials	graph →
→ investigated in trials for	Cyclophosphamidesmall molecule 5 trials (1 active) · roll-up of the cancer and its descendants	—	—	Malignant Oropharyngeal Neoplasm	5	Observed	clinicaltrials	graph →
→ investigated in trials for	Aldesleukinother 4 trials (2 active) · roll-up of the cancer and its descendants	—	—	Malignant Oropharyngeal Neoplasm	4	Observed	clinicaltrials	graph →
→ investigated in trials for	Cemiplimabmonoclonal antibody 4 trials (2 active) · roll-up of the cancer and its descendants	—	—	Malignant Oropharyngeal Neoplasm	4	Observed	clinicaltrials	graph →

Malignant Oropharyngeal Neoplasm investigated in trials for …INVESTIGATED_IN_TRIALSderived15 of 66show all (up to 200)

→ investigated in trials for

Cisplatinsmall molecule

70 trials (33 active) · roll-up of the cancer and its descendants

—

Malignant Oropharyngeal Neoplasm

Observed

Malignant Oropharyngeal Neoplasm studied in …STUDIED_INderived10 of 461show all (up to 200)
→ studied in	NCT03644563active not recruiting Men and Women Offering Understanding of Throat HPV · condition mapped CURATED_EXACT · 461 trials mapped (180 active)	—	—	Malignant Oropharyngeal Neoplasm	1	Observed	clinicaltrials	graph →
→ studied in	NCT07667400Phase 1/Phase 2 · not yet recruiting Docetaxel and SX-682 in Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma, Salivary Gland Carcinoma, and Advanced Prostate Cancer · condition mapped ONTOLOGY_EXACT · 461 trials mapped (180 active)	—	—	Oropharyngeal Squamous Cell Carcinoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT05136196Phase 2 · recruiting BiCaZO: A Study Combining Two Immunotherapies (Cabozantinib and Nivolumab) to Treat Patients With Advanced Melanoma or Squamous Cell Head and Neck Cancer, an immunoMATCH Pilot Study · condition mapped CURATED_BROADER · 461 trials mapped (180 active)	—	—	Oropharyngeal Squamous Cell Carcinoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT06980038Phase 2 · recruiting Testing Whether Cemiplimab (REGN2810) Plus CDX-1140 Given Prior to Surgery Are Better Than Cemiplimab (REGN2810) Alone in Patients With Stage III-IV Head and Neck Cancer · condition mapped ONTOLOGY_EXACT · 461 trials mapped (180 active)	—	—	Oropharyngeal Squamous Cell Carcinoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT05814549active not recruiting A Study Using Human Papillomavirus (HPV) DNA Testing to Detect HPV-Related Oropharyngeal Cancer (OPC) · condition mapped CURATED_EXACT · 461 trials mapped (180 active)	—	—	Malignant Oropharyngeal Neoplasm	1	Observed	clinicaltrials	graph →
→ studied in	NCT06305676recruiting Biomarker Approach to Screening for the Early Detection of HPV-related Oropharyngeal Cancer (BASH OPC) · condition mapped CURATED_EXACT · 461 trials mapped (180 active)	—	—	Malignant Oropharyngeal Neoplasm	1	Observed	clinicaltrials	graph →
→ studied in	NCT04671667Phase 2 · recruiting Testing What Happens When an Immunotherapy Drug (Pembrolizumab) is Given by Itself Compared to the Usual Treatment of Chemotherapy With Radiation After Surgery for Recurrent Head and Neck Squamous Cell Carcinoma · condition mapped CURATED_BROADER · 461 trials mapped (180 active)	—	—	Oropharyngeal Squamous Cell Carcinoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT04708470Phase 1/Phase 2 · completed A Phase I/II Study of Combination Immunotherapy for Advanced Cancers Including HPV-Associated Malignancies, Small Bowel, and Colon Cancers · condition mapped CURATED_EXACT · 461 trials mapped (180 active)	—	—	Malignant Oropharyngeal Neoplasm	1	Observed	clinicaltrials	graph →
→ studied in	NCT05172245Phase 1 · recruiting Testing the Addition of Ipatasertib to Usual Chemotherapy and Radiation for Head and Neck Cancer · condition mapped CURATED_BROADER · 461 trials mapped (180 active)	—	—	Oropharyngeal Squamous Cell Carcinoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT06589804Phase 3 · recruiting Testing the Addition of Anti-Cancer Drug, Cetuximab, to Standard of Care Treatment (Pembrolizumab) for Returning or Spreading Head and Neck Cancer After Previous Treatment · condition mapped CURATED_BROADER · 461 trials mapped (180 active)	—	—	Oropharyngeal Squamous Cell Carcinoma	1	Observed	clinicaltrials	graph →

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