Malignant Intracranial Neoplasm

Observed

→ investigated in trials for

Cyclophosphamidesmall molecule

28 trials (13 active) · roll-up of the cancer and its descendants

—

Observed

→ investigated in trials for

Etoposidesmall molecule

19 trials (7 active) · roll-up of the cancer and its descendants

—

Observed

→ investigated in trials for

Bevacizumabmonoclonal antibody

18 trials (5 active) · roll-up of the cancer and its descendants

—

Observed

→ investigated in trials for

Carboplatinsmall molecule

17 trials (5 active) · roll-up of the cancer and its descendants

—

Observed

→ investigated in trials for

Vincristinesmall molecule

17 trials (6 active) · roll-up of the cancer and its descendants

—

Observed

→ investigated in trials for

Cisplatinsmall molecule

14 trials (5 active) · roll-up of the cancer and its descendants

—

Observed

→ investigated in trials for

Irinotecansmall molecule

14 trials (4 active) · roll-up of the cancer and its descendants

—

Observed

→ investigated in trials for

Nivolumabmonoclonal antibody

13 trials (4 active) · roll-up of the cancer and its descendants

—

Observed

→ investigated in trials for

Filgrastimother

11 trials (4 active) · roll-up of the cancer and its descendants

—

Observed

→ investigated in trials for

Lomustinesmall molecule

11 trials (5 active) · roll-up of the cancer and its descendants

—

Observed

→ investigated in trials for

Topotecansmall molecule

9 trials (2 active) · roll-up of the cancer and its descendants

—

Observed

→ investigated in trials for

Vorinostatsmall molecule

9 trials (0 active) · roll-up of the cancer and its descendants

—

Observed

→ investigated in trials for

Melphalansmall molecule

7 trials (0 active) · roll-up of the cancer and its descendants

—

Observed

→ investigated in trials for

Pembrolizumabmonoclonal antibody

7 trials (4 active) · roll-up of the cancer and its descendants

—

Observed

Malignant Intracranial Neoplasm studied in …STUDIED_INderived10 of 637show all (up to 200)
→ studied in	NCT05685004Phase 2/Phase 3 · active not recruiting Study of Neoantigen-specific Adoptive T Cell Therapy for Newly Diagnosed MGMT Negative Glioblastoma Multiforme (GBM) · condition mapped ALIAS · 637 trials mapped (231 active)	—	—	Brain Glioblastoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT07374692completed Observational Study of Responses to Treatments in Advanced Central Nervous System (CNS) Tumors · condition mapped ALIAS · 637 trials mapped (231 active)	—	—	Malignant Brain Neoplasm	1	Observed	clinicaltrials	graph →
→ studied in	NCT07492316Phase 1 · active not recruiting RNA-lipid Particle (RNA-LP) Vaccines for Recurrent/Progressive Medulloblastoma (MB) · condition mapped CURATED_BROADER · 637 trials mapped (231 active)	—	—	Medulloblastoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT01445288completed Exploratory Study of Effects of Radiation Therapy in Pediatric Patients With Central Nervous System Tumors · condition mapped ONTOLOGY_EXACT · 637 trials mapped (231 active)	—	—	Diffuse Intrinsic Pontine Glioma	1	Observed	clinicaltrials	graph →
→ studied in	NCT07326566Phase 2 · recruiting Study of Silevertinib With Temozolomide for the Treatment of Newly Diagnosed GBM With Unmethylated MGMT and EGFRvIII · condition mapped ALIAS · 637 trials mapped (231 active)	—	—	Malignant Brain Neoplasm	1	Observed	clinicaltrials	graph →
→ studied in	NCT07346157Phase 1/Phase 2 · recruiting Liothyronine in Combination With BIT Regimen for Medulloblastoma With or Without Minimal Residual Disease · condition mapped CURATED_BROADER · 637 trials mapped (231 active)	—	—	Medulloblastoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT07416188Phase 1/Phase 2 · recruiting Novel Indenoisoquinolone CMYC/TOPOISOMERASE 1 Inhibitor (LMP744) in Recurrent Glioblastoma · condition mapped ALIAS · 637 trials mapped (231 active)	—	—	Malignant Brain Neoplasm	1	Observed	clinicaltrials	graph →
→ studied in	NCT02040376Phase 3 · completed Metformin for Brain Repair in Children With Cranial-Spinal Radiation for Medulloblastoma · condition mapped ALIAS · 637 trials mapped (231 active)	—	—	Medulloblastoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT05230758Phase 3 · recruiting Effect of Metformin on Behaviour and the Brain in Children Treated for a Brain Tumour · condition mapped ONTOLOGY_EXACT · 637 trials mapped (231 active)	—	—	Childhood Medulloblastoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT04684368Phase 2 · recruiting A Study of a New Way to Treat Children and Young Adults With a Brain Tumor Called NGGCT · condition mapped ONTOLOGY_EXACT · 637 trials mapped (231 active)	—	—	Pineal Region Yolk Sac Tumor	1	Observed	clinicaltrials	graph →

Malignant Intracranial Neoplasm studied in …STUDIED_INderived10 of 637show all (up to 200)

→ studied in

NCT05685004Phase 2/Phase 3 · active not recruiting

Study of Neoantigen-specific Adoptive T Cell Therapy for Newly Diagnosed MGMT Negative Glioblastoma Multiforme (GBM) · condition mapped ALIAS · 637 trials mapped (231 active)

—

Brain Glioblastoma

Observed

→ studied in

NCT07374692completed

Observational Study of Responses to Treatments in Advanced Central Nervous System (CNS) Tumors · condition mapped ALIAS · 637 trials mapped (231 active)

—

Malignant Brain Neoplasm

Observed

→ studied in

NCT07492316Phase 1 · active not recruiting

RNA-lipid Particle (RNA-LP) Vaccines for Recurrent/Progressive Medulloblastoma (MB) · condition mapped CURATED_BROADER · 637 trials mapped (231 active)

—

Medulloblastoma

Observed

Diffuse Intrinsic Pontine Glioma

→ studied in

NCT01445288completed

Exploratory Study of Effects of Radiation Therapy in Pediatric Patients With Central Nervous System Tumors · condition mapped ONTOLOGY_EXACT · 637 trials mapped (231 active)

—

Observed

→ studied in

NCT07326566Phase 2 · recruiting

Study of Silevertinib With Temozolomide for the Treatment of Newly Diagnosed GBM With Unmethylated MGMT and EGFRvIII · condition mapped ALIAS · 637 trials mapped (231 active)

—

Malignant Brain Neoplasm

Observed

→ studied in

NCT07346157Phase 1/Phase 2 · recruiting

Liothyronine in Combination With BIT Regimen for Medulloblastoma With or Without Minimal Residual Disease · condition mapped CURATED_BROADER · 637 trials mapped (231 active)

—

Medulloblastoma

Observed

→ studied in

NCT07416188Phase 1/Phase 2 · recruiting

Novel Indenoisoquinolone CMYC/TOPOISOMERASE 1 Inhibitor (LMP744) in Recurrent Glioblastoma · condition mapped ALIAS · 637 trials mapped (231 active)

—

Malignant Brain Neoplasm

Observed

→ studied in

NCT02040376Phase 3 · completed

Metformin for Brain Repair in Children With Cranial-Spinal Radiation for Medulloblastoma · condition mapped ALIAS · 637 trials mapped (231 active)

—

Medulloblastoma

Observed

Childhood Medulloblastoma

→ studied in

NCT05230758Phase 3 · recruiting

Effect of Metformin on Behaviour and the Brain in Children Treated for a Brain Tumour · condition mapped ONTOLOGY_EXACT · 637 trials mapped (231 active)

—

Observed

Pineal Region Yolk Sac Tumor

→ studied in

NCT04684368Phase 2 · recruiting

A Study of a New Way to Treat Children and Young Adults With a Brain Tumor Called NGGCT · condition mapped ONTOLOGY_EXACT · 637 trials mapped (231 active)

—

Observed