| Malignant Brain Stem Neoplasm studied in …STUDIED_INderived114 of 114show fewer |
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| → studied in | NCT01445288completed Exploratory Study of Effects of Radiation Therapy in Pediatric Patients With Central Nervous System Tumors · condition mapped ONTOLOGY_EXACT · 114 trials mapped (53 active) | — | — | Diffuse Intrinsic Pontine Glioma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04837547Phase 1 · active not recruiting PEACH TRIAL- Precision Medicine and Adoptive Cellular Therapy · condition mapped ONTOLOGY_EXACT · 114 trials mapped (53 active) | — | — | Diffuse Intrinsic Pontine Glioma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT06838676Phase 2 · recruiting ACT001 for the Treatment of Diffuse Intrinsic Pontine Gliomas and H3K27-altered High Grade Gliomas · condition mapped ALIAS · 114 trials mapped (53 active) | — | — | Diffuse Intrinsic Pontine Glioma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04870944Phase 1/Phase 2 · recruiting CBL0137 for the Treatment of Relapsed or Refractory Solid Tumors, Including CNS Tumors and Lymphoma · condition mapped CURATED_BROADER · 114 trials mapped (53 active) | — | — | Diffuse Intrinsic Pontine Glioma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT06639607Phase 1/Phase 2 · suspended PEP-CMV + Nivolumab for Newly Diagnosed Diffuse Midline Glioma/High-grade Glioma and Recurrent Diffuse Midline Glioma/High-grade Glioma, Medulloblastoma, and Ependymoma · condition mapped PROBABILISTIC · 114 trials mapped (53 active) | — | — | Diffuse Intrinsic Pontine Glioma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT06946680Phase 1 · not yet recruiting IL-8 Receptor-modified CD70 CAR T Cell Therapy in CD70+ Newly Diagnosed and Recurrent Pediatric High-grade Glioma (pHGG) and Newly Diagnosed Diffuse Intrinsic Pontine Glioma (ndDIPG) · condition mapped ONTOLOGY_EXACT · 114 trials mapped (53 active) | — | — | Diffuse Intrinsic Pontine Glioma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT07644312Phase 2 · not yet recruiting Study of Relatlimab and Nivolumab (Opdualag) in Replication Repair Deficient HGG and DIPG · condition mapped ONTOLOGY_EXACT · 114 trials mapped (53 active) | — | — | Diffuse Intrinsic Pontine Glioma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05839379recruiting Targeted Pediatric High-Grade Glioma Therapy · condition mapped ONTOLOGY_EXACT · 114 trials mapped (53 active) | — | — | Diffuse Intrinsic Pontine Glioma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT06465199Phase 1/Phase 2 · recruiting Eflornithine (DFMO) and AMXT 1501 for Neuroblastoma, CNS Tumors, and Sarcomas · condition mapped ONTOLOGY_EXACT · 114 trials mapped (53 active) | — | — | Diffuse Intrinsic Pontine Glioma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT06161974Phase 2 · recruiting Study of Olutasidenib and Temozolomide in HGG · condition mapped ONTOLOGY_EXACT · 114 trials mapped (53 active) | — | — | Diffuse Intrinsic Pontine Glioma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT07796061Phase 1 · not yet recruiting Blood-Brain Barrier Disruption Using Exablate Magnetic Resonance-Guided Low Intensity Focused Ultrasound With Microbubbles in Combination With T-Cell Infusion in Patients With Newly Diagnosed Diffuse Midline Glioma (LIFT) · condition mapped ONTOLOGY_EXACT · 114 trials mapped (53 active) | — | — | Diffuse Intrinsic Pontine Glioma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT07501156Phase 1/Phase 2 · not yet recruiting H3K27M-specific Immune Effector Cells Targeting DMG/DIPG · condition mapped ONTOLOGY_EXACT · 114 trials mapped (53 active) | — | — | Diffuse Intrinsic Pontine Glioma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05096481Phase 2 · recruiting PEP-CMV Vaccine Targeting CMV Antigen to Treat Newly Diagnosed Pediatric HGG and DIPG and Recurrent Medulloblastoma · condition mapped ONTOLOGY_EXACT · 114 trials mapped (53 active) | — | — | Diffuse Intrinsic Pontine Glioma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT07767110Phase 1/Phase 2 · not yet recruiting Targeted LSAM-Cisplatin Infusion in Gliomas, Evaluation of Response · condition mapped ONTOLOGY_EXACT · 114 trials mapped (53 active) | — | — | Diffuse Intrinsic Pontine Glioma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT06894979Phase 1 · active not recruiting Testing the Addition of an Anti-Cancer Drug, AZD1390, During Radiation Therapy for Newly Diagnosed High Grade Glioma, Diffuse Midline Glioma, or Diffuse Intrinsic Pontine Glioma · condition mapped ONTOLOGY_EXACT · 114 trials mapped (53 active) | — | — | Childhood Diffuse Intrinsic Pontine Glioma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03389802Phase 1 · completed Phase I Study of APX005M in Pediatric Central Nervous System Tumors · condition mapped ALIAS · 114 trials mapped (53 active) | — | — | Diffuse Intrinsic Pontine Glioma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05476939Phase 3 · recruiting Biological Medicine for Diffuse Intrinsic Pontine Glioma (DIPG) Eradication 2.0 · condition mapped ONTOLOGY_EXACT · 114 trials mapped (53 active) | — | — | Diffuse Intrinsic Pontine Glioma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01837862Phase 1/Phase 2 · active not recruiting A Phase I Study of Mebendazole for the Treatment of Pediatric Gliomas · condition mapped ONTOLOGY_EXACT · 114 trials mapped (53 active) | — | — | Diffuse Intrinsic Pontine Glioma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT07680439Phase 2 · recruiting Illuminate: A Clinical Study Evaluating CAR T Immune Cell Therapy (BCB-276) for Patients With Diffuse Intrinsic Pontine Glioma (DIPG). · condition mapped ONTOLOGY_EXACT · 114 trials mapped (53 active) | — | — | Diffuse Intrinsic Pontine Glioma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04099797Phase 1 · recruiting C7R-GD2.CAR T Cells for Patients With GD2-expressing Brain Tumors (GAIL-B) · condition mapped ONTOLOGY_EXACT · 114 trials mapped (53 active) | — | — | Diffuse Intrinsic Pontine Glioma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT06624371Phase 1 · recruiting Atovaquone Combined With Radiation in Children With Malignant Brain Tumors · condition mapped ONTOLOGY_EXACT · 114 trials mapped (53 active) | — | — | Diffuse Intrinsic Pontine Glioma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT07206849Phase 2 · not yet recruiting Study of Tovorafenib in High-Grade Glioma and Diffuse Intrinsic Pontine Glioma (DIPG) · condition mapped ONTOLOGY_EXACT · 114 trials mapped (53 active) | — | — | Diffuse Intrinsic Pontine Glioma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03598244Phase 1 · active not recruiting Savolitinib in Treating Patients With Recurrent or Refractory Primary CNS Tumors · condition mapped CURATED_BROADER · 114 trials mapped (53 active) | — | — | Diffuse Intrinsic Pontine Glioma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02359565Phase 1 · active not recruiting Pembrolizumab in Treating Younger Patients With Recurrent, Progressive, or Refractory High-Grade Gliomas, Diffuse Intrinsic Pontine Gliomas, Hypermutated Brain Tumors, Ependymoma or Medulloblastoma · condition mapped CURATED_BROADER · 114 trials mapped (53 active) | — | — | Diffuse Intrinsic Pontine Glioma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05278208Phase 1/Phase 2 · recruiting Lutathera for Treatment of Recurrent or Progressive High-Grade CNS Tumors · condition mapped CURATED_BROADER · 114 trials mapped (53 active) | — | — | Diffuse Intrinsic Pontine Glioma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT06333899early Phase 1 · recruiting Lorlatinib for Newly-Diagnosed High-Grade Glioma With ROS or ALK Fusion · condition mapped ONTOLOGY_EXACT · 114 trials mapped (53 active) | — | — | Diffuse Intrinsic Pontine Glioma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05009992Phase 2 · recruiting Combination Therapy for the Treatment of Diffuse Midline Gliomas · condition mapped ONTOLOGY_EXACT · 114 trials mapped (53 active) | — | — | Diffuse Intrinsic Pontine Glioma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04911621Phase 1/Phase 2 · completed Adjuvant Dendritic Cell Immunotherapy for Pediatric Patients With High-grade Glioma or Diffuse Intrinsic Pontine Glioma · condition mapped ONTOLOGY_EXACT · 114 trials mapped (53 active) | — | — | Diffuse Intrinsic Pontine Glioma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT06607692Phase 1/Phase 2 · recruiting Study in Children and Adolescents of 177Lu-DOTATATE (Lutathera®) Combined With the PARP Inhibitor Olaparib for the Treatment of Recurrent or Relapsed Solid Tumours Expressing Somatostatin Receptor (SSTR) (LuPARPed). · condition mapped ALIAS · 114 trials mapped (53 active) | — | — | Diffuse Intrinsic Pontine Glioma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03033992NA · active not recruiting Optune for Children With High-Grade Glioma or Ependymoma, and Optune With Radiation Therapy for Children With DIPG · condition mapped ONTOLOGY_EXACT · 114 trials mapped (53 active) | — | — | Diffuse Intrinsic Pontine Glioma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04978727Phase 1 · active not recruiting A Pilot Study of SurVaxM in Children Progressive or Relapsed Medulloblastoma, High Grade Glioma, Ependymoma and Newly Diagnosed Diffuse Intrinsic Pontine Glioma · condition mapped ONTOLOGY_EXACT · 114 trials mapped (53 active) | — | — | Diffuse Intrinsic Pontine Glioma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05843253Phase 2 · recruiting Study of Ribociclib and Everolimus in HGG and DIPG or Ribociclib and Temozolomide in DHG, H3G34-mutant · condition mapped ONTOLOGY_EXACT · 114 trials mapped (53 active) | — | — | Diffuse Intrinsic Pontine Glioma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT07589257Phase 2 · recruiting A Study of VRT106 in Combination With Radiotherapy in Adult Patients With Diffuse Midline Glioma / Diffuse Intrinsic Pontine Glioma · condition mapped ONTOLOGY_EXACT · 114 trials mapped (53 active) | — | — | Diffuse Intrinsic Pontine Glioma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04670016completed HRQL and Symptom Assessment for Patients With DIPG or Recurrent and Re-irradiated Brain Tumours and Their Caregivers · condition mapped ALIAS · 114 trials mapped (53 active) | — | — | Diffuse Intrinsic Pontine Glioma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04185038Phase 1 · recruiting Study of B7-H3-Specific CAR T Cell Locoregional Immunotherapy for Diffuse Intrinsic Pontine Glioma/Diffuse Midline Glioma and Recurrent or Refractory Pediatric Central Nervous System Tumors · condition mapped ONTOLOGY_EXACT · 114 trials mapped (53 active) | — | — | Diffuse Intrinsic Pontine Glioma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03605550Phase 1 · active not recruiting A Phase 1b Study of PTC596 in Children With Newly Diagnosed Diffuse Intrinsic Pontine Glioma and High Grade Glioma · condition mapped ONTOLOGY_EXACT · 114 trials mapped (53 active) | — | — | Diffuse Intrinsic Pontine Glioma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03478462Phase 1 · active not recruiting Dose Escalation Study of CLR 131 in Pediatric Relapsed/Refractory Malignant Tumors Including Neuroblastoma and Sarcomas · condition mapped ALIAS · 114 trials mapped (53 active) | — | — | Diffuse Intrinsic Pontine Glioma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04655404early Phase 1 · recruiting A Pilot Study of Larotrectinib for Newly-Diagnosed High-Grade Glioma With NTRK Fusion · condition mapped ONTOLOGY_EXACT · 114 trials mapped (53 active) | — | — | Diffuse Intrinsic Pontine Glioma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04943848Phase 1 · recruiting rHSC-DIPGVax Plus Checkpoint Blockade for the Treatment of Newly Diagnosed DIPG and DMG · condition mapped ONTOLOGY_EXACT · 114 trials mapped (53 active) | — | — | Diffuse Intrinsic Pontine Glioma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01165333Phase 1 · completed Cilengitide in Combination With Irradiation in Children With Diffuse Intrinsic Pontine Glioma · condition mapped ONTOLOGY_EXACT · 114 trials mapped (53 active) | — | — | Diffuse Intrinsic Pontine Glioma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05762419Phase 1 · recruiting FUS Etoposide for DMG · condition mapped ONTOLOGY_EXACT · 114 trials mapped (53 active) | — | — | Diffuse Intrinsic Pontine Glioma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT07331064Phase 1 · not yet recruiting Gallium Maltolate for the Treatment of Pediatric Patients With Relapsed or Refractory Pediatric High-Grade Glioma and Atypical Teratoid Rhabdoid Tumor · condition mapped ALIAS · 114 trials mapped (53 active) | — | — | Diffuse Intrinsic Pontine Glioma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04049669Phase 2 · active not recruiting Pediatric Trial of Indoximod With Chemotherapy and Radiation for Relapsed Brain Tumors or Newly Diagnosed DIPG · condition mapped ONTOLOGY_EXACT · 114 trials mapped (53 active) | — | — | Diffuse Intrinsic Pontine Glioma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04295759Phase 1 · completed INCB7839 in Treating Children With Recurrent/Progressive High-Grade Gliomas · condition mapped ALIAS · 114 trials mapped (53 active) | — | — | Diffuse Intrinsic Pontine Glioma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05956821Phase 1/Phase 2 · recruiting Treatment of Relapsed/Refractory Intracranial Glioma in Patients Under 22 Years of Age · condition mapped ONTOLOGY_EXACT · 114 trials mapped (53 active) | — | — | Diffuse Intrinsic Pontine Glioma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05768880Phase 1 · active not recruiting Study of B7-H3, EGFR806, HER2, And IL13-Zetakine (Quad) CAR T Cell Locoregional Immunotherapy For Pediatric Diffuse Intrinsic Pontine Glioma, Diffuse Midline Glioma, And Recurrent Or Refractory Central Nervous System Tumors · condition mapped ONTOLOGY_EXACT · 114 trials mapped (53 active) | — | — | Diffuse Intrinsic Pontine Glioma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT06521567Phase 1/Phase 2 · active not recruiting A Study of Cobolimab Plus Dostarlimab in Pediatric and Young Adult Participants With Cancer · condition mapped ONTOLOGY_EXACT · 114 trials mapped (53 active) | — | — | Diffuse Intrinsic Pontine Glioma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03396575Phase 1 · terminated Brain Stem Gliomas Treated With Adoptive Cellular Therapy During Focal Radiotherapy Recovery Alone or With Dose-intensified Temozolomide (Phase I) · condition mapped ONTOLOGY_EXACT · 114 trials mapped (53 active) | — | — | Diffuse Intrinsic Pontine Glioma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03101813recruiting International Diffuse Intrinsic Pontine Glioma (DIPG)/Diffuse Midline Glioma (DMG) Registry and Repository · condition mapped ONTOLOGY_EXACT · 114 trials mapped (53 active) | — | — | Diffuse Intrinsic Pontine Glioma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02742883Phase 2 · suspended A Study of Atengenal and Astugenal in Diffuse, Intrinsic Pontine Glioma (DIPG) · condition mapped ONTOLOGY_EXACT · 114 trials mapped (53 active) | — | — | Diffuse Intrinsic Pontine Glioma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03958240NA · recruiting Deciphering Mechanisms Underlying Cancer Immunogenicity · condition mapped ALIAS · 114 trials mapped (53 active) | — | — | Brain Stem Glioblastoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03330197Phase 1/Phase 2 · terminated A Study of Ad-RTS-hIL-12 + Veledimex in Pediatric Subjects With Brain Tumors Including DIPG · condition mapped ONTOLOGY_EXACT · 114 trials mapped (53 active) | — | — | Diffuse Intrinsic Pontine Glioma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04239092Phase 1 · terminated 9-ING-41 in Pediatric Patients With Refractory Malignancies. · condition mapped ONTOLOGY_EXACT · 114 trials mapped (53 active) | — | — | Diffuse Intrinsic Pontine Glioma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03893487early Phase 1 · active not recruiting Fimepinostat in Treating Brain Tumors in Children and Young Adults · condition mapped ONTOLOGY_EXACT · 114 trials mapped (53 active) | — | — | Diffuse Intrinsic Pontine Glioma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04804709Phase 1 · terminated Non-Invasive Focused Ultrasound (FUS) With Oral Panobinostat in Children With Progressive Diffuse Midline Glioma (DMG) · condition mapped ONTOLOGY_EXACT · 114 trials mapped (53 active) | — | — | Diffuse Intrinsic Pontine Glioma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04749641Phase 1 · completed Neoantigen Vaccine Therapy Against H3.3-K27M Diffuse Intrinsic Pontine Glioma · condition mapped ONTOLOGY_EXACT · 114 trials mapped (53 active) | — | — | Diffuse Intrinsic Pontine Glioma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04250064Phase 2 · recruiting A Study of Low Dose Bevacizumab With Conventional Radiotherapy Alone in Diffuse Intrinsic Pontine Glioma · condition mapped ALIAS · 114 trials mapped (53 active) | — | — | Diffuse Intrinsic Pontine Glioma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03690869Phase 1/Phase 2 · terminated REGN2810 in Pediatric Patients With Relapsed, Refractory Solid, or Central Nervous System (CNS) Tumors and Safety and Efficacy of REGN2810 in Combination With Radiotherapy in Pediatric Patients With Newly Diagnosed or Recurrent Glioma · condition mapped ONTOLOGY_EXACT · 114 trials mapped (53 active) | — | — | Diffuse Intrinsic Pontine Glioma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02420613Phase 1 · completed Vorinostat and Temsirolimus With or Without Radiation Therapy in Treating Younger Patients With Newly Diagnosed or Progressive Diffuse Intrinsic Pontine Glioma · condition mapped ONTOLOGY_EXACT · 114 trials mapped (53 active) | — | — | Diffuse Intrinsic Pontine Glioma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT06221553Phase 1 · recruiting Safety and Efficacy of Loco-regional B7H3 IL-7Ra CAR T Cell in DIPG · condition mapped ONTOLOGY_EXACT · 114 trials mapped (53 active) | — | — | Diffuse Intrinsic Pontine Glioma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02992015early Phase 1 · completed Gemcitabine in Newly-Diagnosed Diffuse Intrinsic Pontine Glioma · condition mapped ONTOLOGY_EXACT · 114 trials mapped (53 active) | — | — | Diffuse Intrinsic Pontine Glioma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03416530Phase 1 · terminated ONC201 in Pediatric H3 K27M Gliomas · condition mapped ONTOLOGY_EXACT · 114 trials mapped (53 active) | — | — | Diffuse Intrinsic Pontine Glioma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05298995Phase 1 · recruiting GD2-CAR T Cells for Pediatric Brain Tumours · condition mapped ONTOLOGY_EXACT · 114 trials mapped (53 active) | — | — | Diffuse Intrinsic Pontine Glioma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02960230Phase 1/Phase 2 · completed H3.3K27M Peptide Vaccine With Nivolumab for Children With Newly Diagnosed DIPG and Other Gliomas · condition mapped ONTOLOGY_EXACT · 114 trials mapped (53 active) | — | — | Diffuse Intrinsic Pontine Glioma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03709680Phase 2 · active not recruiting Study Of Palbociclib Combined With Chemotherapy In Pediatric Patients With Recurrent/Refractory Solid Tumors · condition mapped ONTOLOGY_EXACT · 114 trials mapped (53 active) | — | — | Diffuse Intrinsic Pontine Glioma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04758533Phase 1/Phase 2 · active not recruiting Clinical Trial to Assess the Safety and Efficacy of AloCELYVIR With Newly Diagnosed Diffuse Intrinsic Pontine Glioma (DIPG) in Combination With Radiotherapy or Medulloblastoma in Monotherapy · condition mapped ONTOLOGY_EXACT · 114 trials mapped (53 active) | — | — | Diffuse Intrinsic Pontine Glioma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04771897Phase 1 · terminated A Study of BXQ-350 in Children With Newly Diagnosed Diffuse Intrinsic Pontine Glioma (DIPG) or Diffuse Midline Glioma (DMG) · condition mapped ONTOLOGY_EXACT · 114 trials mapped (53 active) | — | — | Diffuse Intrinsic Pontine Glioma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05518838no longer available Expanded Access to OKN-007 for Patients With Diffuse Midline Glioma, H3 K27-altered · condition mapped ONTOLOGY_EXACT · 114 trials mapped (53 active) | — | — | Diffuse Intrinsic Pontine Glioma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05123534Phase 2 · suspended A Phase 2 Study of Sonodynamic Therapy Using SONALA-001 and Exablate 4000 Type 2.0 in Patients with DIPG · condition mapped ONTOLOGY_EXACT · 114 trials mapped (53 active) | — | — | Diffuse Intrinsic Pontine Glioma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01106794recruiting Molecular Analysis of Samples From Patients With Diffuse Intrinsic Pontine Glioma and Brainstem Glioma · condition mapped ONTOLOGY_EXACT · 114 trials mapped (53 active) | — | — | Diffuse Intrinsic Pontine Glioma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT06439849no longer available Single Patient Compassionate Use / Expanded Access L-S-Gboxin (Lyophilized Form of S-Gboxin) for the Treatment of Diffuse Midline Glioma · condition mapped PROBABILISTIC · 114 trials mapped (53 active) | — | — | Diffuse Intrinsic Pontine Glioma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT06140719recruiting xPedite: A Study to Expedite DIPG and DMG Research · condition mapped ALIAS · 114 trials mapped (53 active) | — | — | Diffuse Intrinsic Pontine Glioma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05717699Phase 1 · recruiting Oncolytic Virus Ad-TD-nsIL12 for Progressive Pediatric Diffuse Intrinsic Pontine Glioma · condition mapped ONTOLOGY_EXACT · 114 trials mapped (53 active) | — | — | Diffuse Intrinsic Pontine Glioma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05717712Phase 1 · recruiting Oncolytic Virus Ad-TD-nsIL12 for Primary Pediatric Diffuse Intrinsic Pontine Glioma · condition mapped ONTOLOGY_EXACT · 114 trials mapped (53 active) | — | — | Diffuse Intrinsic Pontine Glioma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04341311Phase 1 · terminated Phase I Study of Marizomib + Panobinostat for Children With DIPG · condition mapped ONTOLOGY_EXACT · 114 trials mapped (53 active) | — | — | Diffuse Intrinsic Pontine Glioma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01922076Phase 1 · completed Adavosertib and Local Radiation Therapy in Treating Children With Newly Diagnosed Diffuse Intrinsic Pontine Gliomas · condition mapped ONTOLOGY_EXACT · 114 trials mapped (53 active) | — | — | Diffuse Intrinsic Pontine Glioma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04264143Phase 1 · completed CED of MTX110 Newly Diagnosed Diffuse Midline Gliomas · condition mapped ONTOLOGY_EXACT · 114 trials mapped (53 active) | — | — | Diffuse Intrinsic Pontine Glioma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03620032Phase 2 · unknown Study of Re-irradiation at Relapse Versus RT and Multiple Elective rt Courses · condition mapped ONTOLOGY_EXACT · 114 trials mapped (53 active) | — | — | Diffuse Intrinsic Pontine Glioma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02644460Phase 1 · completed Abemaciclib in Children With DIPG or Recurrent/Refractory Solid Tumors · condition mapped ONTOLOGY_EXACT · 114 trials mapped (53 active) | — | — | Diffuse Intrinsic Pontine Glioma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT06093165NA · not yet recruiting RE-irradiation of Diffuse MIdline Glioma paTients · condition mapped ONTOLOGY_EXACT · 114 trials mapped (53 active) | — | — | Diffuse Intrinsic Pontine Glioma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03841435NA · completed Hypofractionated Radiotherapy for Recurrent DIPG · condition mapped CURATED_BROADER · 114 trials mapped (53 active) | — | — | Diffuse Intrinsic Pontine Glioma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04532229Phase 3 · unknown Nimotuzumab in Combined With Chemoradiotherapy to Treat the Newly Diagnosed Diffuse Intrinsic Pontine Glioma in Children · condition mapped ONTOLOGY_EXACT · 114 trials mapped (53 active) | — | — | Diffuse Intrinsic Pontine Glioma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05063357Phase 1 · withdrawn 131I-omburtamab Delivered by Convection-Enhanced Delivery in Patients With Diffuse Intrinsic Pontine Glioma · condition mapped ALIAS · 114 trials mapped (53 active) | — | — | Diffuse Intrinsic Pontine Glioma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02444546Phase 1 · completed Wild-Type Reovirus in Combination With Sargramostim in Treating Younger Patients With High-Grade Relapsed or Refractory Brain Tumors · condition mapped ONTOLOGY_EXACT · 114 trials mapped (53 active) | — | — | Diffuse Intrinsic Pontine Glioma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03086616Phase 1 · completed CED With Irinotecan Liposome Injection Using Real Time Imaging in Children With Diffuse Intrinsic Pontine Glioma (DIPG) (PNOC 009) · condition mapped ONTOLOGY_EXACT · 114 trials mapped (53 active) | — | — | Diffuse Intrinsic Pontine Glioma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03355794Phase 1 · completed A Study of Ribociclib and Everolimus Following Radiation Therapy in Children With Newly Diagnosed Non-biopsied Diffuse Pontine Gliomas (DIPG) and RB+ Biopsied DIPG and High Grade Gliomas (HGG) · condition mapped ONTOLOGY_EXACT · 114 trials mapped (53 active) | — | — | Diffuse Intrinsic Pontine Glioma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02274987NA · completed Molecular Profiling for Individualized Treatment Plan for DIPG · condition mapped ONTOLOGY_EXACT · 114 trials mapped (53 active) | — | — | Diffuse Intrinsic Pontine Glioma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01884740Phase 1/Phase 2 · terminated Intraarterial Infusion Of Erbitux and Bevacizumab For Relapsed/Refractory Intracranial Glioma In Patients Under 22 · condition mapped ONTOLOGY_EXACT · 114 trials mapped (53 active) | — | — | Diffuse Intrinsic Pontine Glioma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02644291Phase 1 · completed Phase I Study of Mebendazole Therapy for Recurrent/Progressive Pediatric Brain Tumors · condition mapped ONTOLOGY_EXACT · 114 trials mapped (53 active) | — | — | Malignant Brain Stem Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03243461Phase 3 · unknown International Cooperative Phase III Trial of the HIT-HGG Study Group (HIT-HGG-2013) · condition mapped ONTOLOGY_EXACT · 114 trials mapped (53 active) | — | — | Diffuse Intrinsic Pontine Glioma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02750891Phase 1/Phase 2 · completed A Study of DSP-7888 in Pediatric Patients With Relapsed or Refractory High Grade Gliomas · condition mapped ONTOLOGY_EXACT · 114 trials mapped (53 active) | — | — | Diffuse Intrinsic Pontine Glioma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03566199Phase 1/Phase 2 · completed MTX110 by Convection-Enhanced Delivery in Treating Participants With Newly-Diagnosed Diffuse Intrinsic Pontine Glioma · condition mapped ONTOLOGY_EXACT · 114 trials mapped (53 active) | — | — | Diffuse Intrinsic Pontine Glioma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01222754Phase 1 · completed Lenalidomide and Radiation Therapy in High Grade Gliomas or Diffuse Intrinsic Pontine Gliomas · condition mapped ONTOLOGY_EXACT · 114 trials mapped (53 active) | — | — | Diffuse Intrinsic Pontine Glioma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01189266Phase 1/Phase 2 · completed Vorinostat and Radiation Therapy Followed by Maintenance Therapy With Vorinostat in Treating Younger Patients With Newly Diagnosed Diffuse Intrinsic Pontine Glioma · condition mapped ONTOLOGY_EXACT · 114 trials mapped (53 active) | — | — | Diffuse Intrinsic Pontine Glioma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03387020Phase 1 · completed Ribociclib and Everolimus in Treating Children With Recurrent or Refractory Malignant Brain Tumors · condition mapped CURATED_BROADER · 114 trials mapped (53 active) | — | — | Diffuse Intrinsic Pontine Glioma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT00879437Phase 2 · completed Valproic Acid, Radiation, and Bevacizumab in Children With High Grade Gliomas or Diffuse Intrinsic Pontine Glioma · condition mapped ONTOLOGY_EXACT · 114 trials mapped (53 active) | — | — | Diffuse Intrinsic Pontine Glioma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02758366Phase 2 · terminated Prolonged Exposure to Doxorubicin in Patients With Glioblastoma Multiforme and Diffuse Intrinsic Pontine Glioma · condition mapped ALIAS · 114 trials mapped (53 active) | — | — | Diffuse Intrinsic Pontine Glioma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04668508Phase 2 · unknown Anlotinib to Malignant Brainstem Glioma · condition mapped ALIAS · 114 trials mapped (53 active) | — | — | Malignant Brain Stem Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02607124Phase 1/Phase 2 · terminated A Phase I/II Study of Ribociclib,a CDK4/6 Inhibitor, Following Radiation Therapy · condition mapped ONTOLOGY_EXACT · 114 trials mapped (53 active) | — | — | Diffuse Intrinsic Pontine Glioma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02502708Phase 1 · completed Study of the IDO Pathway Inhibitor, Indoximod, and Temozolomide for Pediatric Patients With Progressive Primary Malignant Brain Tumors · condition mapped ONTOLOGY_EXACT · 114 trials mapped (53 active) | — | — | Diffuse Intrinsic Pontine Glioma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01400672Phase 1 · terminated Imiquimod/Brain Tumor Initiating Cell (BTIC) Vaccine in Brain Stem Glioma · condition mapped ONTOLOGY_EXACT · 114 trials mapped (53 active) | — | — | Diffuse Intrinsic Pontine Glioma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04051047early Phase 1 · withdrawn Gemcitabine in Newly-Diagnosed Diffuse Midline Glioma · condition mapped ONTOLOGY_EXACT · 114 trials mapped (53 active) | — | — | Diffuse Intrinsic Pontine Glioma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01182350Phase 2 · terminated Molecularly Determined Treatment of Diffuse Intrinsic Pontine Gliomas (DIPG) · condition mapped ONTOLOGY_EXACT · 114 trials mapped (53 active) | — | — | Diffuse Intrinsic Pontine Glioma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03632317Phase 2 · withdrawn A Study of Panobinostat in Combination With Everolimus for Children and Young Adults With Gliomas · condition mapped ONTOLOGY_EXACT · 114 trials mapped (53 active) | — | — | Diffuse Intrinsic Pontine Glioma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01688401Phase 1 · completed Intra-arterial Chemotherapy for the Treatment of Progressive Diffuse Intrinsic Pontine Gliomas (DIPG). · condition mapped ONTOLOGY_EXACT · 114 trials mapped (53 active) | — | — | Diffuse Intrinsic Pontine Glioma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01644773Phase 1 · completed Study of the Combination of Crizotinib and Dasatinib in Pediatric Research Participants With Diffuse Pontine Glioma (DIPG) and High-Grade Glioma (HGG) · condition mapped ONTOLOGY_EXACT · 114 trials mapped (53 active) | — | — | Diffuse Intrinsic Pontine Glioma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02233049Phase 2 · unknown Biological Medicine for Diffuse Intrinsic Pontine Glioma (DIPG) Eradication · condition mapped ONTOLOGY_EXACT · 114 trials mapped (53 active) | — | — | Diffuse Intrinsic Pontine Glioma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT00890786early Phase 1 · completed A Study of Bevacizumab Therapy in Patients With Newly Diagnosed High-Grade Gliomas and Diffuse Intrinsic Pontine Gliomas · condition mapped ONTOLOGY_EXACT · 114 trials mapped (53 active) | — | — | Diffuse Intrinsic Pontine Glioma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02840123Phase 1 · unknown Safety Study of DIPG Treatment With Autologous Dendritic Cells Pulsed With Lysated Allegenic Tumor Lines · condition mapped ONTOLOGY_EXACT · 114 trials mapped (53 active) | — | — | Diffuse Intrinsic Pontine Glioma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01393912Phase 1 · completed PDGFR Inhibitor Crenolanib in Children/Young Adults With Diffuse Intrinsic Pontine Glioma or Recurrent High-Grade Glioma · condition mapped ONTOLOGY_EXACT · 114 trials mapped (53 active) | — | — | Diffuse Intrinsic Pontine Glioma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01952769Phase 1/Phase 2 · unknown Anti PD1 Antibody in Diffuse Intrinsic Pontine Glioma · condition mapped ALIAS · 114 trials mapped (53 active) | — | — | Diffuse Intrinsic Pontine Glioma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT00996723Phase 1 · completed Clinical Trial Evaluating the Combination of Vandetanib and Dasatinib During and After Radiation Therapy (RT) in Children With Newly Diagnosed Diffuse Intrinsic Pontine Glioma (DIPG) · condition mapped ONTOLOGY_EXACT · 114 trials mapped (53 active) | — | — | Diffuse Intrinsic Pontine Glioma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT00036569Phase 2 · completed A Phase II Study of Pegylated Interferon Alfa 2b (PEG-Intron(Trademark)) in Children With Diffuse Pontine Gliomas · condition mapped ONTOLOGY_EXACT · 114 trials mapped (53 active) | — | — | Diffuse Intrinsic Pontine Glioma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT00600054Phase 2 · completed Phase 2 Study of Nimotuzumab in Pediatric Recurrent Diffuse Intrinsic Pontine Glioma · condition mapped ONTOLOGY_EXACT · 114 trials mapped (53 active) | — | — | Diffuse Intrinsic Pontine Glioma | 1 | Observed | clinicaltrials | graph → |