Malignant Brain Glioma

subtype

Identifier: CI-CAN-00005868
Entity page: /cancer/malignant-brain-glioma ↗
Edges: 243

Neighbours: 15 drugs10 trials
Drawn: 25 of 25 neighbours (cap 60); table lists every fetched edge

Accepted: cancer:<slug>, gene:<symbol>, variant:<slug>, drug:<slug>, trial:<NCT id>, or a bare CI id. Find slugs with search.

Most connectedLung Non-Small Cell Carcinoma 3,147 Malignant Colorectal Neoplasm 1,866 ABL1 298 EGFR 276 Imatinib 450 Dasatinib 321

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Focus at the centre; neighbours grouped by entity type. Click a node to re-centre the graph on it; ↗ opens the entity page. Hover a spoke for relationship, evidence level, cancer context and source.

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Source-native edges first (aggregated per neighbour, direction, evidence level and source), then derived registry links. Up to 15 per relationship (10 trials); “show all” raises one group to 200.

Relationship	Neighbour	Direction	Evidence level	Cancer context	Support	Claim	Source	Expand
Malignant Brain Glioma investigated in trials for …INVESTIGATED_IN_TRIALSderived15 of 56show all (up to 200)
→ investigated in trials for	Temozolomidesmall molecule 28 trials (12 active) · roll-up of the cancer and its descendants	—	—	Malignant Brain Glioma	28	Observed	clinicaltrials	graph →
→ investigated in trials for	Bevacizumabmonoclonal antibody

Malignant Brain Glioma studied in …STUDIED_INderived10 of 187show all (up to 200)
→ studied in	NCT05685004Phase 2/Phase 3 · active not recruiting Study of Neoantigen-specific Adoptive T Cell Therapy for Newly Diagnosed MGMT Negative Glioblastoma Multiforme (GBM) · condition mapped ALIAS · 187 trials mapped (83 active)	—	—	Brain Glioblastoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT01445288completed Exploratory Study of Effects of Radiation Therapy in Pediatric Patients With Central Nervous System Tumors · condition mapped ONTOLOGY_EXACT · 187 trials mapped (83 active)	—	—	Diffuse Intrinsic Pontine Glioma	1	Observed	clinicaltrials	graph →
→ studied in	NCT04837547Phase 1 · active not recruiting PEACH TRIAL- Precision Medicine and Adoptive Cellular Therapy · condition mapped ONTOLOGY_EXACT · 187 trials mapped (83 active)	—	—	Diffuse Intrinsic Pontine Glioma	1	Observed	clinicaltrials	graph →
→ studied in	NCT03197506Phase 2 · active not recruiting Pembrolizumab and Standard Therapy in Treating Patients With Glioblastoma · condition mapped ONTOLOGY_EXACT · 187 trials mapped (83 active)	—	—	Supratentorial Glioblastoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT06838676Phase 2 · recruiting ACT001 for the Treatment of Diffuse Intrinsic Pontine Gliomas and H3K27-altered High Grade Gliomas · condition mapped ALIAS · 187 trials mapped (83 active)	—	—	Diffuse Intrinsic Pontine Glioma	1	Observed	clinicaltrials	graph →
→ studied in	NCT04870944Phase 1/Phase 2 · recruiting CBL0137 for the Treatment of Relapsed or Refractory Solid Tumors, Including CNS Tumors and Lymphoma · condition mapped CURATED_BROADER · 187 trials mapped (83 active)	—	—	Diffuse Intrinsic Pontine Glioma	1	Observed	clinicaltrials	graph →
→ studied in	NCT06639607Phase 1/Phase 2 · suspended PEP-CMV + Nivolumab for Newly Diagnosed Diffuse Midline Glioma/High-grade Glioma and Recurrent Diffuse Midline Glioma/High-grade Glioma, Medulloblastoma, and Ependymoma · condition mapped PROBABILISTIC · 187 trials mapped (83 active)	—	—	Diffuse Intrinsic Pontine Glioma	1	Observed	clinicaltrials	graph →
→ studied in	NCT05052957Phase 2 · recruiting hSTAR GBM (Hematopoetic Stem Cell (HPC) Rescue for GBM) · condition mapped ONTOLOGY_EXACT · 187 trials mapped (83 active)	—	—	Supratentorial Glioblastoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT06613841early Phase 1 · recruiting Multitracer [18F]Fluciclovine and 18F-FDG PET, and Advanced MRI for Metabolic Profiling of Glioblastoma · condition mapped ALIAS · 187 trials mapped (83 active)	—	—	Brain Glioblastoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT06946680Phase 1 · not yet recruiting IL-8 Receptor-modified CD70 CAR T Cell Therapy in CD70+ Newly Diagnosed and Recurrent Pediatric High-grade Glioma (pHGG) and Newly Diagnosed Diffuse Intrinsic Pontine Glioma (ndDIPG) · condition mapped ONTOLOGY_EXACT · 187 trials mapped (83 active)	—	—	Diffuse Intrinsic Pontine Glioma	1	Observed	clinicaltrials	graph →

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