Desmoplastic Small Round Cell Tumor

subtype

Identifier: CI-CAN-00002515
Entity page: /cancer/desmoplastic-small-round-cell-tumor ↗
Edges: 90

Neighbours: 1 genes1 variants19 drugs10 trials
Drawn: 31 of 31 neighbours (cap 60); table lists every fetched edge

Accepted: cancer:<slug>, gene:<symbol>, variant:<slug>, drug:<slug>, trial:<NCT id>, or a bare CI id. Find slugs with search.

Most connectedLung Non-Small Cell Carcinoma 3,149 Malignant Colorectal Neoplasm 1,866 ABL1 298 EGFR 276 Imatinib 450 Dasatinib 321

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Source-native edges first (aggregated per neighbour, direction, evidence level and source), then derived registry links. Up to 15 per relationship (10 trials); “show all” raises one group to 200.

Relationship	Neighbour	Direction	Evidence level	Cancer context	Support	Claim	Source	Expand
Desmoplastic Small Round Cell Tumor diagnostic of …DIAGNOSTIC_OF2 of 2
← diagnostic of	WT1 Fusionfusion 2 source records aggregated	supports	B	Desmoplastic Small Round Cell Tumor	2	Curated	civic	graph →
← diagnostic of	WT1 Fusionfusion	supports

Desmoplastic Small Round Cell Tumor associated with …ASSOCIATED_WITH2 of 2
← associated with	WT1 2 source records aggregated	supports	B	Desmoplastic Small Round Cell Tumor	2	Curated	civic	graph →
← associated with	WT1	supports	C	Desmoplastic Small Round Cell Tumor	1	Curated	civic	graph →

Desmoplastic Small Round Cell Tumor associated with …ASSOCIATED_WITH2 of 2

← associated with

WT1

2 source records aggregated

supports

Desmoplastic Small Round Cell Tumor investigated for …INVESTIGATED_FOR9 of 9
← investigated for	Vinorelbinesmall_molecule	unknown	1	Desmoplastic Small Round Cell Tumor	1	Curated	chembl	graph →
← investigated for	Topotecansmall_molecule	unknown	1	Desmoplastic Small Round Cell Tumor	1	Curated	chembl	graph →
← investigated for	Ramucirumabmonoclonal_antibody	unknown	1	Desmoplastic Small Round Cell Tumor	1	Curated	chembl	graph →
← investigated for	Imatinib Mesylatesmall_molecule	unknown	1	Desmoplastic Small Round Cell Tumor	1	Curated	chembl	graph →
← investigated for	Imatinibsmall_molecule	unknown	1	Desmoplastic Small Round Cell Tumor	1	Curated	chembl	graph →
← investigated for	Cyclophosphamidesmall_molecule	unknown	1	Desmoplastic Small Round Cell Tumor	1	Curated	chembl	graph →
← investigated for	Temozolomidesmall_molecule	unknown	0.5	Desmoplastic Small Round Cell Tumor	1	Curated	chembl	graph →
← investigated for	Irinotecansmall_molecule	unknown	0.5	Desmoplastic Small Round Cell Tumor	1	Curated	chembl	graph →
← investigated for	Bevacizumabmonoclonal_antibody	unknown	0.5	Desmoplastic Small Round Cell Tumor	1	Curated	chembl	graph →

Desmoplastic Small Round Cell Tumor investigated in trials for …INVESTIGATED_IN_TRIALSderived15 of 36show all (up to 200)
→ investigated in trials for	Cyclophosphamidesmall_molecule 4 trials (1 active) · roll-up of the cancer and its descendants	—	—	Desmoplastic Small Round Cell Tumor	4	Observed	clinicaltrials	graph →
→ investigated in trials for	Doxorubicinsmall molecule 4 trials (1 active) · roll-up of the cancer and its descendants	—	—	Desmoplastic Small Round Cell Tumor	4	Observed	clinicaltrials	graph →
→ investigated in trials for	Etoposidesmall molecule 2 trials (0 active) · roll-up of the cancer and its descendants	—	—	Desmoplastic Small Round Cell Tumor	2	Observed	clinicaltrials	graph →
→ investigated in trials for	Fludarabinesmall molecule 2 trials (1 active) · roll-up of the cancer and its descendants	—	—	Desmoplastic Small Round Cell Tumor	2	Observed	clinicaltrials	graph →
→ investigated in trials for	Ifosfamidesmall molecule 2 trials (1 active) · roll-up of the cancer and its descendants	—	—	Desmoplastic Small Round Cell Tumor	2	Observed	clinicaltrials	graph →
→ investigated in trials for	Imatinib Mesylatesmall_molecule 2 trials (0 active) · roll-up of the cancer and its descendants	—	—	Desmoplastic Small Round Cell Tumor	2	Observed	clinicaltrials	graph →
→ investigated in trials for	Irinotecansmall_molecule 2 trials (1 active) · roll-up of the cancer and its descendants	—	—	Desmoplastic Small Round Cell Tumor	2	Observed	clinicaltrials	graph →
→ investigated in trials for	Lurbinectedinsmall molecule 2 trials (2 active) · roll-up of the cancer and its descendants	—	—	Desmoplastic Small Round Cell Tumor	2	Observed	clinicaltrials	graph →
→ investigated in trials for	Pembrolizumabmonoclonal antibody 2 trials (2 active) · roll-up of the cancer and its descendants	—	—	Desmoplastic Small Round Cell Tumor	2	Observed	clinicaltrials	graph →
→ investigated in trials for	Temozolomidesmall_molecule 2 trials (1 active) · roll-up of the cancer and its descendants	—	—	Desmoplastic Small Round Cell Tumor	2	Observed	clinicaltrials	graph →
→ investigated in trials for	Vincristinesmall molecule 2 trials (1 active) · roll-up of the cancer and its descendants	—	—	Desmoplastic Small Round Cell Tumor	2	Observed	clinicaltrials	graph →
→ investigated in trials for	Bevacizumabmonoclonal_antibody 1 trials (0 active) · roll-up of the cancer and its descendants	—	—	Desmoplastic Small Round Cell Tumor	1	Observed	clinicaltrials	graph →
→ investigated in trials for	Cisplatinsmall molecule 1 trials (0 active) · roll-up of the cancer and its descendants	—	—	Desmoplastic Small Round Cell Tumor	1	Observed	clinicaltrials	graph →
→ investigated in trials for	Cixutumumabmonoclonal antibody 1 trials (0 active) · roll-up of the cancer and its descendants	—	—	Desmoplastic Small Round Cell Tumor	1	Observed	clinicaltrials	graph →
→ investigated in trials for	Filgrastimother 1 trials (1 active) · roll-up of the cancer and its descendants	—	—	Desmoplastic Small Round Cell Tumor	1	Observed	clinicaltrials	graph →

Desmoplastic Small Round Cell Tumor studied in …STUDIED_INderived10 of 41show all (up to 200)
→ studied in	NCT04616560Phase 2 · recruiting Trastuzumab Deruxtecan (DS-8201a) for the Treatment of Recurrent or Refractory Osteosarcoma, Wilms Tumor, and Desmoplastic Small Round Cell Tumor · condition mapped ONTOLOGY_EXACT · 41 trials mapped (17 active)	—	—	Desmoplastic Small Round Cell Tumor	1	Observed	clinicaltrials	graph →
→ studied in	NCT07695311Phase 1 · not yet recruiting EWSR1 Immunotherapy in Ewing Sarcoma and DSRCT · condition mapped ONTOLOGY_EXACT · 41 trials mapped (17 active)	—	—	Desmoplastic Small Round Cell Tumor	1	Observed	clinicaltrials	graph →
→ studied in	NCT01189643early Phase 1 · active not recruiting Irinotecan, Temozolomide and Bevacizumab in Combination With Existing High Dose Alkylator Based Chemotherapy for Treatment of Newly Diagnosed Patients With Desmoplastic Small Round Cell Tumor · condition mapped ONTOLOGY_EXACT · 41 trials mapped (17 active)	—	—	Desmoplastic Small Round Cell Tumor	1	Observed	clinicaltrials	graph →
→ studied in	NCT05918640Phase 1/Phase 2 · recruiting Lurbinectedin in FET-Fused Tumors · condition mapped ONTOLOGY_EXACT · 41 trials mapped (17 active)	—	—	Desmoplastic Small Round Cell Tumor	1	Observed	clinicaltrials	graph →
→ studied in	NCT07328425Phase 2 · recruiting Clinical Study in Adult and Young Adult Patients With Advanced Desmoplastic Small Round Cell Tumor (DSRCT) ISG-TULIPS · condition mapped ONTOLOGY_EXACT · 41 trials mapped (17 active)	—	—	Desmoplastic Small Round Cell Tumor	1	Observed	clinicaltrials	graph →
→ studied in	NCT01946529Phase 2 · completed Therapeutic Trial for Patients With Ewing Sarcoma Family of Tumor and Desmoplastic Small Round Cell Tumors · condition mapped ONTOLOGY_EXACT · 41 trials mapped (17 active)	—	—	Desmoplastic Small Round Cell Tumor	1	Observed	clinicaltrials	graph →
→ studied in	NCT04145349Phase 1/Phase 2 · completed CAMPFIRE: A Study of Ramucirumab (LY3009806) in Children and Young Adults With Desmoplastic Small Round Cell Tumor · condition mapped ONTOLOGY_EXACT · 41 trials mapped (17 active)	—	—	Desmoplastic Small Round Cell Tumor	1	Observed	clinicaltrials	graph →
→ studied in	NCT04022213Phase 2 · active not recruiting A Study of the Drug I131-Omburtamab in People With Desmoplastic Small Round Cell Tumors and Other Solid Tumors in the Peritoneum · condition mapped ONTOLOGY_EXACT · 41 trials mapped (17 active)	—	—	Desmoplastic Small Round Cell Tumor	1	Observed	clinicaltrials	graph →
→ studied in	NCT03874455no longer available Tazemetostat Expanded Access Program for Adults With Solid Tumors · condition mapped ONTOLOGY_EXACT · 41 trials mapped (17 active)	—	—	Desmoplastic Small Round Cell Tumor	1	Observed	clinicaltrials	graph →
→ studied in	NCT06625190Phase 1/Phase 2 · recruiting Alpha/Beta T and B Cell Depletion With Zoledronic Acid for Solid Tumors · condition mapped ONTOLOGY_EXACT · 41 trials mapped (17 active)	—	—	Desmoplastic Small Round Cell Tumor	1	Observed	clinicaltrials	graph →

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