Anal Neoplasm

subtype

Identifier: CI-CAN-00004468
Entity page: /cancer/anal-neoplasm ↗
Edges: 349

Neighbours: 20 drugs10 trials
Drawn: 30 of 30 neighbours (cap 60); table lists every fetched edge

Accepted: cancer:<slug>, gene:<symbol>, variant:<slug>, drug:<slug>, trial:<NCT id>, or a bare CI id. Find slugs with search.

Most connectedLung Non-Small Cell Carcinoma 3,147 Malignant Colorectal Neoplasm 1,866 ABL1 298 EGFR 276 Imatinib 450 Dasatinib 321

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Source-native edges first (aggregated per neighbour, direction, evidence level and source), then derived registry links. Up to 15 per relationship (10 trials); “show all” raises one group to 200.

Relationship	Neighbour	Direction	Evidence level	Cancer context	Support	Claim	Source	Expand
Anal Neoplasm investigated for …INVESTIGATED_FOR14 of 14
← investigated for	Mitomycinsmall_molecule	unknown	3	Anal Neoplasm	1	Curated	chembl	graph →
← investigated for	Fluorouracilsmall_molecule	unknown	3

Anal Neoplasm investigated in trials for …INVESTIGATED_IN_TRIALSderived15 of 37show all (up to 200)
→ investigated in trials for	Fluorouracilsmall_molecule 24 trials (3 active) · roll-up of the cancer and its descendants	—	—	Anal Neoplasm	24	Observed	clinicaltrials	graph →
→ investigated in trials for	Mitomycinsmall_molecule 16 trials (5 active) · roll-up of the cancer and its descendants	—	—	Anal Neoplasm	16	Observed	clinicaltrials	graph →
→ investigated in trials for	Capecitabinesmall_molecule 11 trials (5 active) · roll-up of the cancer and its descendants	—	—	Anal Neoplasm	11	Observed	clinicaltrials	graph →
→ investigated in trials for	Cisplatinsmall_molecule 10 trials (0 active) · roll-up of the cancer and its descendants	—	—	Anal Neoplasm	10	Observed	clinicaltrials	graph →
→ investigated in trials for	Nivolumabmonoclonal antibody 8 trials (7 active) · roll-up of the cancer and its descendants	—	—	Anal Neoplasm	8	Observed	clinicaltrials	graph →
→ investigated in trials for	Pembrolizumabmonoclonal_antibody 7 trials (5 active) · roll-up of the cancer and its descendants	—	—	Anal Neoplasm	7	Observed	clinicaltrials	graph →
→ investigated in trials for	Cetuximabmonoclonal_antibody 6 trials (0 active) · roll-up of the cancer and its descendants	—	—	Anal Neoplasm	6	Observed	clinicaltrials	graph →
→ investigated in trials for	Paclitaxelsmall_molecule 6 trials (2 active) · roll-up of the cancer and its descendants	—	—	Anal Neoplasm	6	Observed	clinicaltrials	graph →
→ investigated in trials for	Aldesleukinother 5 trials (2 active) · roll-up of the cancer and its descendants	—	—	Anal Neoplasm	5	Observed	clinicaltrials	graph →
→ investigated in trials for	Carboplatinsmall_molecule 5 trials (2 active) · roll-up of the cancer and its descendants	—	—	Anal Neoplasm	5	Observed	clinicaltrials	graph →
→ investigated in trials for	Cyclophosphamidesmall molecule 4 trials (1 active) · roll-up of the cancer and its descendants	—	—	Anal Neoplasm	4	Observed	clinicaltrials	graph →
→ investigated in trials for	Fludarabinesmall molecule 4 trials (1 active) · roll-up of the cancer and its descendants	—	—	Anal Neoplasm	4	Observed	clinicaltrials	graph →
→ investigated in trials for	Chemotherapy 3 trials (2 active) · roll-up of the cancer and its descendants	—	—	Anal Neoplasm	3	Observed	clinicaltrials	graph →
→ investigated in trials for	Ipilimumabmonoclonal antibody 3 trials (2 active) · roll-up of the cancer and its descendants	—	—	Anal Neoplasm	3	Observed	clinicaltrials	graph →
→ investigated in trials for	Irinotecansmall_molecule 3 trials (0 active) · roll-up of the cancer and its descendants	—	—	Anal Neoplasm	3	Observed	clinicaltrials	graph →

Anal Neoplasm investigated in trials for …INVESTIGATED_IN_TRIALSderived15 of 37show all (up to 200)

→ investigated in trials for

Fluorouracilsmall_molecule

24 trials (3 active) · roll-up of the cancer and its descendants

—

Anal Neoplasm

Observed

Anal Neoplasm studied in …STUDIED_INderived10 of 298show all (up to 200)
→ studied in	NCT07124000recruiting DESTINY-PANTUMOUR04 · condition mapped CURATED_EXACT · 298 trials mapped (100 active)	—	—	Malignant Anal Neoplasm	1	Observed	clinicaltrials	graph →
→ studied in	NCT02314169Phase 2 · active not recruiting Nivolumab With or Without Ipilimumab in Treating Patients With Refractory Metastatic Anal Canal Cancer · condition mapped ONTOLOGY_EXACT · 298 trials mapped (100 active)	—	—	Anal Canal Squamous Cell Carcinoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT04708470Phase 1/Phase 2 · completed A Phase I/II Study of Combination Immunotherapy for Advanced Cancers Including HPV-Associated Malignancies, Small Bowel, and Colon Cancers · condition mapped CURATED_EXACT · 298 trials mapped (100 active)	—	—	Malignant Anal Neoplasm	1	Observed	clinicaltrials	graph →
→ studied in	NCT06263088NA · recruiting EQUITY GI: A Prospective Study to Enhance Quality, Inclusivity, and Trial Participation in Black Patients With Gastrointestinal Cancer. · condition mapped CURATED_EXACT · 298 trials mapped (100 active)	—	—	Malignant Anal Neoplasm	1	Observed	clinicaltrials	graph →
→ studied in	NCT07217171Phase 1 · recruiting A Study Evaluating the Safety, Efficacy, and Pharmacokinetics (PK) of EVOLVE104 in Participants With Advanced Urothelial and Squamous Cell Carcinomas · condition mapped ONTOLOGY_EXACT · 298 trials mapped (100 active)	—	—	Anal Squamous Cell Carcinoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT07775209Phase 2 · enrolling by invitation Shortening Radiation Course Duration Using Simultaneous Integrated Boost With Lower Intensity Elective Nodal Dosing and Concurrent Chemotherapy for High-Risk Anal Squamous Cell Carcinoma · condition mapped CURATED_EXACT · 298 trials mapped (100 active)	—	—	Malignant Anal Neoplasm	1	Observed	clinicaltrials	graph →
→ studied in	NCT03074513Phase 2 · active not recruiting Atezolizumab and Bevacizumab in Treating Patients With Rare Solid Tumors · condition mapped ONTOLOGY_EXACT · 298 trials mapped (100 active)	—	—	Human Papillomavirus-Related Anal Squamous Cell Carcinoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT04166318Phase 2 · active not recruiting Lower-Dose Chemoradiation in Treating Patients With Early-Stage Anal Cancer, the DECREASE Study · condition mapped ONTOLOGY_EXACT · 298 trials mapped (100 active)	—	—	Anal Basaloid Carcinoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT05109468completed Assessment of Patients' Quality of Sexual Life After Anal Cancer Treatment · condition mapped CURATED_EXACT · 298 trials mapped (100 active)	—	—	Malignant Anal Neoplasm	1	Observed	clinicaltrials	graph →
→ studied in	NCT05858736Phase 1 · completed Safety, PK and Efficacy of AI-061 in Advanced Solid Tumors · condition mapped CURATED_EXACT · 298 trials mapped (100 active)	—	—	Malignant Anal Neoplasm	1	Observed	clinicaltrials	graph →

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