Adrenal Cortical Neoplasm

Observed

← altered in cohorts of

AVPR1A

70 / 92 cases (76 %) · ssm · TCGA-ACC

—

Observed

← altered in cohorts of

BAZ2A

70 / 92 cases (76 %) · ssm · TCGA-ACC

—

Observed

← altered in cohorts of

CAND1

70 / 92 cases (76 %) · ssm · TCGA-ACC

—

Observed

← altered in cohorts of

HSD17B6

70 / 92 cases (76 %) · ssm · TCGA-ACC

—

Observed

← altered in cohorts of

NACA

70 / 92 cases (76 %) · ssm · TCGA-ACC

—

Observed

← altered in cohorts of

AGAP2

69 / 92 cases (75 %) · ssm · TCGA-ACC

—

Observed

← altered in cohorts of

ATP23

69 / 92 cases (75 %) · ssm · TCGA-ACC

—

Observed

← altered in cohorts of

ATP5F1B

69 / 92 cases (75 %) · ssm · TCGA-ACC

—

Observed

← altered in cohorts of

AVIL

69 / 92 cases (75 %) · ssm · TCGA-ACC

—

Observed

← altered in cohorts of

BIN2

69 / 92 cases (75 %) · ssm · TCGA-ACC

—

Observed

← altered in cohorts of

CDK4

69 / 92 cases (75 %) · ssm · TCGA-ACC

—

Observed

← altered in cohorts of

CTDSP2

69 / 92 cases (75 %) · ssm · TCGA-ACC

—

Observed

← altered in cohorts of

CYP27B1

69 / 92 cases (75 %) · ssm · TCGA-ACC

—

Observed

← altered in cohorts of

DYRK2

69 / 92 cases (75 %) · ssm · TCGA-ACC

—

Observed

Adrenal Cortical Neoplasm investigated in trials for …INVESTIGATED_IN_TRIALSderived15 of 34show all (up to 200)
→ investigated in trials for	Mitotanesmall_molecule 7 trials (1 active) · roll-up of the cancer and its descendants	—	—	Adrenal Cortical Neoplasm	7	Observed	clinicaltrials	graph →
→ investigated in trials for	Pembrolizumabmonoclonal_antibody 7 trials (5 active) · roll-up of the cancer and its descendants	—	—	Adrenal Cortical Neoplasm	7	Observed	clinicaltrials	graph →
→ investigated in trials for	Cabozantinibsmall molecule 5 trials (3 active) · roll-up of the cancer and its descendants	—	—	Adrenal Cortical Neoplasm	5	Observed	clinicaltrials	graph →
→ investigated in trials for	Cisplatinsmall_molecule 5 trials (1 active) · roll-up of the cancer and its descendants	—	—	Adrenal Cortical Neoplasm	5	Observed	clinicaltrials	graph →
→ investigated in trials for	Nivolumabmonoclonal_antibody 5 trials (2 active) · roll-up of the cancer and its descendants	—	—	Adrenal Cortical Neoplasm	5	Observed	clinicaltrials	graph →
→ investigated in trials for	Doxorubicinsmall_molecule 4 trials (0 active) · roll-up of the cancer and its descendants	—	—	Adrenal Cortical Neoplasm	4	Observed	clinicaltrials	graph →
→ investigated in trials for	Cyclophosphamidesmall molecule 3 trials (2 active) · roll-up of the cancer and its descendants	—	—	Adrenal Cortical Neoplasm	3	Observed	clinicaltrials	graph →
→ investigated in trials for	Camrelizumabmonoclonal antibody 2 trials (1 active) · roll-up of the cancer and its descendants	—	—	Adrenal Cortical Neoplasm	2	Observed	clinicaltrials	graph →
→ investigated in trials for	Cemiplimabmonoclonal antibody 2 trials (2 active) · roll-up of the cancer and its descendants	—	—	Adrenal Cortical Neoplasm	2	Observed	clinicaltrials	graph →
→ investigated in trials for	Cixutumumabmonoclonal antibody 2 trials (0 active) · roll-up of the cancer and its descendants	—	—	Adrenal Cortical Neoplasm	2	Observed	clinicaltrials	graph →
→ investigated in trials for	Etoposidesmall_molecule 2 trials (0 active) · roll-up of the cancer and its descendants	—	—	Adrenal Cortical Neoplasm	2	Observed	clinicaltrials	graph →
→ investigated in trials for	Fludarabinesmall molecule 2 trials (2 active) · roll-up of the cancer and its descendants	—	—	Adrenal Cortical Neoplasm	2	Observed	clinicaltrials	graph →
→ investigated in trials for	Ipilimumabmonoclonal antibody 2 trials (2 active) · roll-up of the cancer and its descendants	—	—	Adrenal Cortical Neoplasm	2	Observed	clinicaltrials	graph →
→ investigated in trials for	Abiraterone Acetatesmall molecule 1 trials (0 active) · roll-up of the cancer and its descendants	—	—	Adrenal Cortical Neoplasm	1	Observed	clinicaltrials	graph →
→ investigated in trials for	Axitinibsmall molecule 1 trials (0 active) · roll-up of the cancer and its descendants	—	—	Adrenal Cortical Neoplasm	1	Observed	clinicaltrials	graph →

Adrenal Cortical Neoplasm investigated in trials for …INVESTIGATED_IN_TRIALSderived15 of 34show all (up to 200)

→ investigated in trials for

Mitotanesmall_molecule

7 trials (1 active) · roll-up of the cancer and its descendants

—

Observed

→ investigated in trials for

Pembrolizumabmonoclonal_antibody

7 trials (5 active) · roll-up of the cancer and its descendants

—

Observed

→ investigated in trials for

Cabozantinibsmall molecule

5 trials (3 active) · roll-up of the cancer and its descendants

—

Observed

→ investigated in trials for

Cisplatinsmall_molecule

5 trials (1 active) · roll-up of the cancer and its descendants

—

Observed

→ investigated in trials for

Nivolumabmonoclonal_antibody

5 trials (2 active) · roll-up of the cancer and its descendants

—

Observed

→ investigated in trials for

Doxorubicinsmall_molecule

4 trials (0 active) · roll-up of the cancer and its descendants

—

Observed

→ investigated in trials for

Cyclophosphamidesmall molecule

3 trials (2 active) · roll-up of the cancer and its descendants

—

Observed

→ investigated in trials for

Camrelizumabmonoclonal antibody

2 trials (1 active) · roll-up of the cancer and its descendants

—

Observed

→ investigated in trials for

Cemiplimabmonoclonal antibody

2 trials (2 active) · roll-up of the cancer and its descendants

—

Observed

→ investigated in trials for

Cixutumumabmonoclonal antibody

2 trials (0 active) · roll-up of the cancer and its descendants

—

Observed

→ investigated in trials for

Etoposidesmall_molecule

2 trials (0 active) · roll-up of the cancer and its descendants

—

Observed

→ investigated in trials for

Fludarabinesmall molecule

2 trials (2 active) · roll-up of the cancer and its descendants

—

Observed

→ investigated in trials for

Ipilimumabmonoclonal antibody

2 trials (2 active) · roll-up of the cancer and its descendants

—

Observed

→ investigated in trials for

Abiraterone Acetatesmall molecule

1 trials (0 active) · roll-up of the cancer and its descendants

—

Observed

→ investigated in trials for

Axitinibsmall molecule

1 trials (0 active) · roll-up of the cancer and its descendants

—

Observed

Adrenal Cortical Neoplasm studied in …STUDIED_INderived10 of 105show all (up to 200)
→ studied in	NCT06487481Phase 1 · recruiting Study of Preoperative Radiation Therapy in Participants With Resectable Recurrent Abdominal Adrenocortical Carcinoma · condition mapped ALIAS · 105 trials mapped (37 active)	—	—	Adrenal Cortical Carcinoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT07715903Phase 1 · not yet recruiting Hepatic Artery Infusion of Carfilzomib in Participants With Liver Metastatic Disease Previously Treated With Hepatic Artery Infusion Pump Therapy · condition mapped ALIAS · 105 trials mapped (37 active)	—	—	Adrenal Cortical Carcinoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT06900595Phase 2 · recruiting Testing the Addition of an Anti-Cancer Drug, Cabozantinib to the Immunotherapy Drug Cemiplimab (REGN2810), in Adolescents and Adults With Advanced Adrenocortical Cancer · condition mapped CURATED_BROADER · 105 trials mapped (37 active)	—	—	Adrenal Cortical Carcinoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT07743138Phase 2 · not yet recruiting STOMP OUT: A Phase 2 Study To Evaluate The Effects Of Ivonescimab In Patients With Unresectable/Metastatic Adrenocortical Carcinoma (ACC) Or Unresectable Pheochromocytoma/Paraganglioma (PPGL) · condition mapped ALIAS · 105 trials mapped (37 active)	—	—	Adrenal Cortical Carcinoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT05286814Phase 2 · recruiting PDS01ADC in Combination With Hepatic Artery Infusion Pump (HAIP) and Systemic Therapy for Subjects With Metastatic Colorectal Cancer, Intrahepatic Cholangiocarcinoma, or Metastatic Adrenocortical Carcinoma · condition mapped ALIAS · 105 trials mapped (37 active)	—	—	Adrenal Cortical Neoplasm	1	Observed	clinicaltrials	graph →
→ studied in	NCT06279442completed Adrenal Project: Clinical and Epidemiological Characterization of Adrenocortical Carcinoma in a Brazilian Cohort · condition mapped PROBABILISTIC · 105 trials mapped (37 active)	—	—	Adrenal Cortical Neoplasm	1	Observed	clinicaltrials	graph →
→ studied in	NCT02867592Phase 2 · active not recruiting Cabozantinib-S-Malate in Treating Younger Patients With Recurrent, Refractory, or Newly Diagnosed Sarcomas, Wilms Tumor, or Other Rare Tumors · condition mapped ONTOLOGY_EXACT · 105 trials mapped (37 active)	—	—	Adrenal Cortical Carcinoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT00453674recruiting German Adrenocortical Carcinoma Registry · condition mapped ALIAS · 105 trials mapped (37 active)	—	—	Adrenal Cortical Carcinoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT03333616Phase 2 · active not recruiting Nivolumab Combined With Ipilimumab for Patients With Advanced Rare Genitourinary Tumors · condition mapped ALIAS · 105 trials mapped (37 active)	—	—	Adrenal Cortical Carcinoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT02721732Phase 2 · active not recruiting Pembrolizumab in Treating Patients With Rare Tumors That Cannot Be Removed by Surgery or Are Metastatic · condition mapped CURATED_BROADER · 105 trials mapped (37 active)	—	—	Adrenal Cortical Carcinoma	1	Observed	clinicaltrials	graph →

Adrenal Cortical Neoplasm studied in …STUDIED_INderived10 of 105show all (up to 200)

→ studied in

NCT06487481Phase 1 · recruiting

Study of Preoperative Radiation Therapy in Participants With Resectable Recurrent Abdominal Adrenocortical Carcinoma · condition mapped ALIAS · 105 trials mapped (37 active)

—

Observed

→ studied in

NCT07715903Phase 1 · not yet recruiting

Hepatic Artery Infusion of Carfilzomib in Participants With Liver Metastatic Disease Previously Treated With Hepatic Artery Infusion Pump Therapy · condition mapped ALIAS · 105 trials mapped (37 active)

—

Observed

→ studied in

NCT06900595Phase 2 · recruiting

Testing the Addition of an Anti-Cancer Drug, Cabozantinib to the Immunotherapy Drug Cemiplimab (REGN2810), in Adolescents and Adults With Advanced Adrenocortical Cancer · condition mapped CURATED_BROADER · 105 trials mapped (37 active)

—

Observed

→ studied in

NCT07743138Phase 2 · not yet recruiting

STOMP OUT: A Phase 2 Study To Evaluate The Effects Of Ivonescimab In Patients With Unresectable/Metastatic Adrenocortical Carcinoma (ACC) Or Unresectable Pheochromocytoma/Paraganglioma (PPGL) · condition mapped ALIAS · 105 trials mapped (37 active)

—

Observed

→ studied in

NCT05286814Phase 2 · recruiting

PDS01ADC in Combination With Hepatic Artery Infusion Pump (HAIP) and Systemic Therapy for Subjects With Metastatic Colorectal Cancer, Intrahepatic Cholangiocarcinoma, or Metastatic Adrenocortical Carcinoma · condition mapped ALIAS · 105 trials mapped (37 active)

—

Observed

→ studied in

NCT06279442completed

Adrenal Project: Clinical and Epidemiological Characterization of Adrenocortical Carcinoma in a Brazilian Cohort · condition mapped PROBABILISTIC · 105 trials mapped (37 active)

—

Observed

→ studied in

NCT02867592Phase 2 · active not recruiting

Cabozantinib-S-Malate in Treating Younger Patients With Recurrent, Refractory, or Newly Diagnosed Sarcomas, Wilms Tumor, or Other Rare Tumors · condition mapped ONTOLOGY_EXACT · 105 trials mapped (37 active)

—

Observed

→ studied in

NCT00453674recruiting

German Adrenocortical Carcinoma Registry · condition mapped ALIAS · 105 trials mapped (37 active)

—

Observed

→ studied in

NCT03333616Phase 2 · active not recruiting

Nivolumab Combined With Ipilimumab for Patients With Advanced Rare Genitourinary Tumors · condition mapped ALIAS · 105 trials mapped (37 active)

—

Observed

→ studied in

NCT02721732Phase 2 · active not recruiting

Pembrolizumab in Treating Patients With Rare Tumors That Cannot Be Removed by Surgery or Are Metastatic · condition mapped CURATED_BROADER · 105 trials mapped (37 active)

—

Observed