Gene

VEGFC

vascular endothelial growth factor C

Explore in graph →CI-GENE-00038357HGNC:12682 ENSG00000150630 NCBI 7424 CIViC Approved

Curated evidence

Clinical evidence (1)

CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.

civicCuratedShowing 1–1 of 1 evidence items · levels, directions and significance as curated at the source; each row links to its CIViC record.

Therapy	Cancer	Type	Level	Direction · significance	Rating (1–5)	Status	Evidence	Source
VEGFC Overexpression1
Sunitinib	Hepatocellular Carcinoma	Predictive	B	Supports Sensitivity Response	4	submitted	EID7987 Phase 2 trial of adult hepatocellular patients treated with sunitinib analyzed how baseline concentration of different soluble VEGF proteins predict overall survival (OS) and time to progression (TTP)… (full text at CIViC) PMID 21787417 · Harmon et al., 2011 · Open in CIViC	civic

Cohorts

Alteration frequency by cohort (4)

Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.

cbioportalObserved4 cohort rows · frequency = affected / profiled, as published by each cohort; cohorts are not pooled. Hover a row badge for its release.

Cohort	Mapped cancer	Alteration	Affected (n)	Profiled (n)	Frequency (%)	Rank in cohort	Source
Cholangiocarcinoma (National University of Singapore, Nat Genet 2012) chol_nus_2012	Cholangiocarcinoma	Ssm	1	8

Literature

Linked publications (0)

Data not yet available

No publication linked to this gene yet.