AMER1

APC membrane recruitment protein 1

Explore in graph →CI-GENE-00010678HGNC:26837 ENSG00000184675 NCBI 139285 CIViC Cancer geneApproved

Curated evidence

Clinical evidence (1)

CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.

civicCuratedShowing 1–1 of 1 evidence items · levels, directions and significance as curated at the source; each row links to its CIViC record.

Therapy	Cancer	Type	Level	Direction · significance	Rating (1–5)	Status	Evidence	Source
AMER1 R358X1
(diagnostic)	Wilms TumorCURATED_BROADER	Diagnostic	B	Supports Positive	3	rejected	EID6079 This variant was detected in one patient belonging to the Kenyan Wilms Tumor patient cohort from sub-Saharan Africa. PMID 26274016 · Lovvorn et al., 2015 · Open in CIViC	civic

Cohorts

Alteration frequency by cohort (125)

Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.

cbioportalObserved125 cohort rows (showing 50, sorted by frequency) · frequency = affected / profiled, as published by each cohort; cohorts are not pooled. Hover a row badge for its release.

Cohort	Mapped cancer	Alteration	Affected (n)	Profiled (n)	Frequency (%)	Rank in cohort	Source
Thoracic Cancer (MSK, Nat Commun 2021) lung_pdx_msk_2021	unmapped	Ssm	2	69

Literature

Linked publications (0)

Data not yet available

No publication linked to this gene yet.