Wilms Tumor — Genomics

Wilms Tumor — Genomics · CancerIndex

Genomics

Gene alteration frequencies by cohort

4 cohorts mapped to this entity or its descendants. Each frequency is affected / profiled within one cohort; cohorts are shown separately because case selection, sequencing depth and definitions differ. By default the cohort with the most cases profiled is shown.

High-Risk Wilms Tumor TARGET-WTTARGET

631 cases with simple somatic mutation data · 652 cases total · Data Release 46.0 · mapped to Wilms Tumor CURATED_BROADER

gdcObserved30 genes · frequency = affected / profiled, as published by the cohort.

#	Gene	Alteration	Affected (n)	Profiled (n)	Frequency (%)	Source
1	TP53	Ssm	13	631	2.1%	gdc
2	BCOR	Ssm	3	631	0.5%	gdc
3	TTN	Ssm	3	631	0.5%	gdc
7	MLLT1	Ssm	2	631	0.3%	gdc
6	FAM184B	Ssm	2	631	0.3%	gdc
5	WT1	Ssm	2	631	0.3%	gdc
4	CSMD2	Ssm	2	631	0.3%	gdc
9	TENM1	Ssm	2

Data updated 23 days agoSource updated Data Release 46.0

Molecular Profiling to Predict Response to Treatment - Wilms Tumor MP2PRT-WTMP2PRT

51 cases with simple somatic mutation data · 52 cases total · Data Release 46.0 · mapped to Wilms Tumor ONTOLOGY_EXACT

gdcObserved30 genes · frequency = affected / profiled, as published by the cohort.

#	Gene	Alteration	Affected (n)	Profiled (n)	Frequency (%)	Source
10

Pediatric Wilms' Tumor (TARGET, 2018) wt_target_2018_pubTARGET

657 cases with simple somatic mutation data · 657 cases total · 2026-01-16 · mapped to Wilms Tumor EXACT_IDENTIFIER

cbioportalObserved30 genes · frequency = affected / profiled, as published by the cohort.

#	Gene	Alteration	Affected (n)	Profiled (n)	Frequency (%)	Source
1	TP53	Ssm	15	657

Wilms' Tumor (TARGET GDC, 2025) wt_target_gdcTARGET GDC

42 cases with simple somatic mutation data · 132 cases total · 2026-01-19 · mapped to Wilms Tumor EXACT_IDENTIFIER

cbioportalObserved30 genes · frequency = affected / profiled, as published by the cohort.

#	Gene	Alteration	Affected (n)	Profiled (n)	Frequency (%)	Source
1	TP53	Ssm	13	42	31%

Cohorts mapped to a descendant (e.g. a subtype) are included because their cases belong to this entity by definition; the mapping and its match type are shown per cohort.