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CancerIndexthe global index of cancer

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CancerIndex

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Neuroepithelial, Perineurial, and Schwann Cell Neoplasm — Research · CancerIndex

Cancers
Neoplasm
Neoplasm by Morphology
Neuroepithelial, Perineurial, and Schwann Cell Neoplasm

Cancer Family

Neuroepithelial, Perineurial, and Schwann Cell Neoplasm

CI-CAN-00000039Explore in graph →

Non-malignant864 active trials6 approved drugs159 evidence items

NCIt: C35562

Overview
Statistics
Survival
Genomics30
Variants & evidence159
Drugs35
Trials3130
Research
Rankings
Sources & provenance

Research activity

PubMed record counts

Each count is the number of PubMed records returned by the exact query shown, at the time it was run. Counts are research-activity signals, not quality measures.

Data not yet available

No PubMed query has been run for this entity. Counts require a MeSH-anchored query built from the entity's terminology mappings; the query string is stored with each count so it can be reproduced.

What CancerIndex knows

Trials tab
Methodology: publication counts

Literature

Linked publications (117)

Publications linked to this entity or its descendants, newest first, 25 per page. Link method and validation status are shown; 'candidate' links have not been reviewed.

pubmedProvenance

Source: PubMed (NLM)
Dataset: PubMed E-utilities
Retrieved: Sep 8, 2026
Layer: normalized (units and labels harmonized; values unchanged)

PublishedShowing 26–50 of 117 publications · bibliographic data as recorded by PubMed; abstracts are not reproduced.

Genomic analysis of diffuse pediatric low-grade gliomas identifies recurrent oncogenic truncating rearrangements in the transcription factor MYBL1.
· Proc Natl Acad Sci U S A · 2013 · PMID 23633565 · validated civic_curation pubmed
Childhood supratentorial ependymomas with YAP1-MAMLD1 fusion: an entity with characteristic clinical, radiological, cytogenetic and histopathological features.
· Brain Pathol · 2019 · PMID 30246434 · validated civic_curation pubmed
Entrectinib in children and young adults with solid or primary CNS tumors harboring NTRK, ROS1, or ALK aberrations (STARTRK-NG).
· Neuro Oncol · 2022 · PMID 35395680 · validated civic_curation pubmed
Genomic analysis demonstrates that histologically-defined astroblastomas are molecularly heterogeneous and that tumors with MN1 rearrangement exhibit the most favorable prognosis.
· Acta Neuropathol Commun · 2019 · PMID 30876455 · validated civic_curation pubmed
Loss of PTEN is not associated with poor survival in newly diagnosed glioblastoma patients of the temozolomide era.
· PLoS One · 2012 · PMID 22479427 · validated civic_curation pubmed
IDH1 mutations in low-grade astrocytomas predict survival but not response to temozolomide.
· Neurology · 2009 · PMID 19933982 · validated civic_curation pubmed
The prognostic IDH1( R132 ) mutation is associated with reduced NADP+-dependent IDH activity in glioblastoma.

Showing 26–50 of 117 publications

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· Acta Neuropathol · 2010 · PMID 20127344 · validated civic_curation pubmed

Prognostic value of epidermal growth factor receptor in patients with glioblastoma multiforme.

· Cancer Res · 2003 · PMID 14583498 · validated civic_curation pubmed

The MGMT promoter SNP rs16906252 is a risk factor for MGMT methylation in glioblastoma and is predictive of response to temozolomide.

· Neuro Oncol · 2015 · PMID 25910840 · validated civic_curation pubmed

A phase II, multicenter trial of rindopepimut (CDX-110) in newly diagnosed glioblastoma: the ACT III study.

· Neuro Oncol · 2015 · PMID 25586468 · validated civic_curation pubmed

ATRX loss refines the classification of anaplastic gliomas and identifies a subgroup of IDH mutant astrocytic tumors with better prognosis.

· Acta Neuropathol · 2013 · PMID 23904111 · validated civic_curation pubmed

Correlation between O6-methylguanine-DNA methyltransferase and survival in inoperable newly diagnosed glioblastoma patients treated with neoadjuvant temozolomide.

· J Clin Oncol · 2007 · PMID 17442989 · validated civic_curation pubmed

O-methylguanine-DNA methyltransferase (MGMT) mRNA expression predicts outcome in malignant glioma independent of MGMT promoter methylation.

· PLoS One · 2011 · PMID 21365007 · validated civic_curation pubmed

O6-methylguanine DNA methyltransferase expression in tumor cells predicts outcome of radiotherapy plus concomitant and adjuvant temozolomide therapy in patients with primary glioblastoma.

· Brain Tumor Pathol · 2011 · PMID 21331613 · validated civic_curation pubmed

Recurrent somatic mutations in ACVR1 in pediatric midline high-grade astrocytoma.

· Nat Genet · 2014 · PMID 24705250 · validated civic_curation pubmed

The genomic landscape of diffuse intrinsic pontine glioma and pediatric non-brainstem high-grade glioma.

· Nat Genet · 2014 · PMID 24705251 · validated civic_curation pubmed

Somatic histone H3 alterations in pediatric diffuse intrinsic pontine gliomas and non-brainstem glioblastomas.

· Nat Genet · 2012 · PMID 22286216 · validated civic_curation pubmed

TERT promoter mutations occur frequently in gliomas and a subset of tumors derived from cells with low rates of self-renewal.

· Proc Natl Acad Sci U S A · 2013 · PMID 23530248 · validated civic_curation pubmed

Genomic analysis of diffuse intrinsic pontine gliomas identifies three molecular subgroups and recurrent activating ACVR1 mutations.

· Nat Genet · 2014 · PMID 24705254 · validated civic_curation pubmed

Polymorphisms of CDKN1A gene and risk of retinoblastoma.

· Carcinogenesis · 2013 · PMID 24045412 · validated civic_curation pubmed

Selumetinib in paediatric patients with BRAF-aberrant or neurofibromatosis type 1-associated recurrent, refractory, or progressive low-grade glioma: a multicentre, phase 2 trial.

· Lancet Oncol · 2019 · PMID 31151904 · validated civic_curation pubmed

Whole-exome sequencing identifies ATRX mutation as a key molecular determinant in lower-grade glioma.

· Oncotarget · 2012 · PMID 23104868 · validated civic_curation pubmed

Recurrent activating ACVR1 mutations in diffuse intrinsic pontine glioma.

· Nat Genet · 2014 · PMID 24705252 · validated civic_curation pubmed

A single-arm phase II Austrian/German multicenter trial on continuous daily sunitinib in primary glioblastoma at first recurrence (SURGE 01-07).

· Neuro Oncol · 2014 · PMID 24311637 · validated civic_curation pubmed

Histone H3F3A and HIST1H3B K27M mutations define two subgroups of diffuse intrinsic pontine gliomas with different prognosis and phenotypes.

· Acta Neuropathol · 2015 · PMID 26399631 · validated civic_curation pubmed