Publication
Polymorphisms of CDKN1A gene and risk of retinoblastoma.
Authors not recorded
- Source
- PubMed
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CIVIC-20260908-000001
Abstract
Abstract (excerpt)
Only the opening of the abstract is shown; abstract text may carry publisher copyright.
Data not yet available
Linked entities
Linked entities (4)
How each link was made (MeSH, dictionary, registry reference, curation…) and whether it has been validated. Candidate links are not counted in entity statistics.
Validated 4
- cancerRetinoblastomacivic_curation1.00
- geneCDKN1Acivic_curation1.00
- variantCDKN1A rs1059234civic_curation1.00
- variantCDKN1A rs1801270civic_curation1.00
Curated evidence
Evidence citing this paper (3)
- Source
- CIViC — Clinical Interpretation of Variants in Cancer
- Dataset
- CIViC evidence items
- Version
- civic-2026-09-08
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- expert curation
- License
- CC0 1.0
- PMID
- 24045412
- Run
- ING-CIVIC-20260908-000001
| Therapy | Cancer | Type | Level | Direction · significance | Rating (1–5) | Status | Evidence | Source |
|---|---|---|---|---|---|---|---|---|
| CDKN1A rs10592341 | ||||||||
| (predisposing) | Retinoblastoma | Predisposing | B | Supports Predisposition | 3 | accepted | EID9244This study examined two CDKN1A polymorphisms (rs1801270 and rs1059234) in 141 carriers of RB1 variants and 120 unrelated healthy individuals. Authors found that RB1 carriers were more likely to have t… (full text at CIViC) PMID 24045412 · Carvalho et al., 2013 · Open in CIViC | civic |
| CDKN1A rs18012701 | ||||||||
| (predisposing) | Retinoblastoma | Predisposing | B | Supports Predisposition | 3 | accepted | EID7227This study examined two CDKN1A polymorphisms (rs1801270 and rs1059234) in 141 carriers of RB1 variants and 120 unrelated healthy individuals. Authors found that RB1 carriers were more likely to have t… (full text at CIViC) PMID 24045412 · Carvalho et al., 2013 · Open in CIViC | civic |
| CDKN1A rs1801270 and rs10592341 | ||||||||
| (predisposing) | Retinoblastoma | Predisposing | B | Supports Predisposition | 3 | submitted | EID9245This study examined two CDKN1A polymorphisms (rs1801270 and rs1059234) in 141 carriers of RB1 variants and 120 unrelated healthy individuals. Authors found the chance of developing retinoblastoma incr… (full text at CIViC) PMID 24045412 · Carvalho et al., 2013 · Open in CIViC | civic |