Cancer Family
Nervous System Neoplasm
CI-CAN-00000038Explore in graph →
Non-malignant1,523 active trials9 approved drugs210 evidence items
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Cancer Family
CI-CAN-00000038Explore in graph →
Clinical trials
5,873 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT04738162 | Clinical Safety Study on 5-Aminolevulinic Acid (5-ALA) in Children and Adolescents With Brain Tumors | completed | Phase 2 | 78 | Universität MünsterOTHER | 2 | Dec 10, 2025 | clinicaltrials |
| NCT05432375 | Study of Tinostamustine for Adjuvant Treatment of Glioblastoma | completed | Early Phase 1 | 10 | Mundipharma Research LimitedINDUSTRY | 2 | Dec 10, 2025 | clinicaltrials |
| NCT04391062 |
| Dose Finding for Intraoperative Photodynamic Therapy of Glioblastoma(DOSINDYGO) |
| completed |
| Phase 2 |
| 14 |
| University Hospital, LilleOTHER |
| 2 |
| Dec 5, 2025 |
| clinicaltrials |
| NCT02238899 | Multicenter Register for Children and Young Adults With Intracranial Localized Medulloblastoma, CNS-PNET or Ependymoma | completed | — | 354 | Universitätsklinikum Hamburg-EppendorfOTHER | 1 | Dec 4, 2025 | clinicaltrials |
| NCT04306484 | 18F-DOPA-PET in Non-tumoral and Tumoral Brain Lesions(FDOPA) | completed | — | 74 | Centre Hospitalier Universitaire de NīmesOTHER | 1 | Dec 4, 2025 | clinicaltrials |
| NCT04503772 | Preoperative Stereotactic Radiosurgery for Brain Metastases(STEP) | completed | Phase 2 | 70 | Centre Jean PerrinOTHER | 1 | Dec 4, 2025 | clinicaltrials |
| NCT04116658 | First-in-Human, Phase 1b/2a Trial of a Multipeptide Therapeutic Vaccine in Patients With Progressive Glioblastoma(ROSALIE) | completed | Phase 1 / Phase 2 | 100 | EnteromeINDUSTRY | 4 | Nov 28, 2025 | clinicaltrials |
| NCT03224104 | Multi-kinase Inhibitor TG02 (TG02) in Elderly Newly Diagnosed or Adult Relapsed Patients With Anaplastic Astrocytoma or Glioblastoma.(STEAM) | completed | Phase 1 | 71 | European Organisation for Research and Treatment of Cancer - EORTCNETWORK | 5 | Nov 26, 2025 | clinicaltrials |
| NCT01373710 | Intrathecal Trastuzumab Administration in Metastatic Breast Cancer Patients Developing Carcinomatous Meningitis(HIT) | completed | Phase 1 / Phase 2 | 34 | Institut CurieOTHER | 1 | Nov 24, 2025 | clinicaltrials |
| NCT01582269 | A Study in Recurrent Glioblastoma (GB) | completed | Phase 2 | 158 | Eli Lilly and CompanyINDUSTRY | 10 | Nov 24, 2025 | clinicaltrials |
| NCT05848050 | Evaluation of the Humoral and Tumoral Molecular Alteration Profile of Brain Metastases(METALIQ) | completed | N/A | 21 | GCS Ramsay Santé pour l'Enseignement et la RechercheOTHER | 1 | Nov 24, 2025 | clinicaltrials |
| NCT03532295 | Retifanlimab and Epacadostat in Combination With Radiation and Bevacizumab in Patients With Recurrent Gliomas | completed | Phase 2 | 51 | Washington University School of MedicineOTHER | 1 | Nov 21, 2025 | clinicaltrials |
| NCT01602666 | Chemotherapy Followed by Radiation Therapy in Treating Younger Patients With Newly Diagnosed Localized Central Nervous System Germ Cell Tumors | completed | Phase 2 | 262 | Children's Oncology GroupNETWORK | 5 | Nov 20, 2025 | clinicaltrials |
| NCT04987476 | Rhabdoid Tumors Cellular Architecture by Single-cell Analyses (InnovRT-2)(InnovRT-2) | completed | — | 15 | Assistance Publique - Hôpitaux de ParisOTHER | 1 | Nov 20, 2025 | clinicaltrials |
| NCT05762172 | Dynamic F-DOPA PET for Differential Diagnosis Between Recurrence and Radionecrosis of Brain Metastasis(DYNDOPATEP) | completed | N/A | 8 | Centre Hospitalier Universitaire, AmiensOTHER | 1 | Nov 18, 2025 | clinicaltrials |
| NCT02939300 | Ipilimumab and Nivolumab in Leptomeningeal Metastases | completed | Phase 2 | 18 | Massachusetts General HospitalOTHER | 1 | Nov 14, 2025 | clinicaltrials |
| NCT03746080 | Whole Brain Radiation Therapy With Standard Temozolomide Chemo-Radiotherapy and Plerixafor in Treating Patients With Glioblastoma | completed | Phase 2 | 21 | Lawrence D RechtOTHER | 1 | Nov 14, 2025 | clinicaltrials |
| NCT01180881 | Neurobehavioral Functioning in Pediatric Brain Tumor Patients After Proton Beam Radiation Treatment | completed | — | 155 | Massachusetts General HospitalOTHER | 1 | Nov 10, 2025 | clinicaltrials |
| NCT02684838 | Vigilant ObservatIon of GlIadeL WAfer ImplaNT Registry(VIGILANT) | completed | — | 272 | Arbor Pharmaceuticals, Inc.INDUSTRY | 1 | Nov 10, 2025 | clinicaltrials |
| NCT03412812 | A Dose Escalation Trial of Five Fraction Stereotactic Radiation Therapy for Brain Metastases(RAD1705) | completed | N/A | 13 | University of Alabama at BirminghamOTHER | 1 | Nov 4, 2025 | clinicaltrials |
| NCT02162732 | Molecular-Guided Therapy for Childhood Cancer | completed | N/A | 186 | Giselle ShollerOTHER | 2 | Nov 3, 2025 | clinicaltrials |
| NCT01270724 | Gemcitabine, Paclitaxel and Oxaliplatin (GemPOx) | completed | Phase 2 | 10 | Nationwide Children's HospitalOTHER | 1 | Oct 27, 2025 | clinicaltrials |
| NCT04826393 | ASP8374 + Cemiplimab in Recurrent Glioma | completed | Phase 1 | 14 | Dana-Farber Cancer InstituteOTHER | 1 | Oct 22, 2025 | clinicaltrials |
| NCT01991977 | 18F-DOPA-PET in Finding Tumors in Patients With Newly Diagnosed Gliomas Undergoing Radiation Therapy | completed | Phase 2 | 91 | Mayo ClinicOTHER | 1 | Oct 20, 2025 | clinicaltrials |
| NCT03076255 | Using a Head and Neck Maskless Immobilization Device For Patients With Intracranial Tumors | completed | N/A | 12 | Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson UniversityOTHER | 1 | Oct 15, 2025 | clinicaltrials |
| NCT00807027 | Clinical Trial to Assess the Efficacy and Safety of 'Immuncell-LC' With Temozolomide in Newly Diagnosed Glioblastoma of Korea | completed | Phase 3 | 180 | GC Cell CorporationINDUSTRY | 1 | Oct 10, 2025 | clinicaltrials |
| NCT06180460 | CALM: Managing Distress in Malignant Brain Cancer | completed | N/A | 60 | Virginia Commonwealth UniversityOTHER | 1 | Oct 8, 2025 | clinicaltrials |
| NCT02285439 | Study of MEK162 for Children With Low-Grade Gliomas | completed | Phase 1 / Phase 2 | 105 | Children's Hospital Los AngelesOTHER | 1 | Oct 7, 2025 | clinicaltrials |
| NCT03033303 | A Study of the Effect of Hu3F8/GM-CSF Immunotherapy Plus Isotretinoin in Patients in First Remission of High-Risk Neuroblastoma | completed | Phase 2 | 59 | Memorial Sloan Kettering Cancer CenterOTHER | 1 | Oct 7, 2025 | clinicaltrials |
| NCT03426891 | Pembrolizumab and Vorinostat Combined With Temozolomide for Newly Diagnosed Glioblastoma | completed | Phase 1 | 21 | H. Lee Moffitt Cancer Center and Research InstituteOTHER | 1 | Oct 6, 2025 | clinicaltrials |
| NCT04631029 | Testing the Addition of an Anti-cancer Drug, Entinostat, to the Usual Chemotherapy and Immunotherapy Treatment (Atezolizumab, Carboplatin and Etoposide) for Previously Untreated Aggressive Lung Cancer That Has Spread | completed | Phase 1 | 3 | National Cancer Institute (NCI)NIH | 1 | Oct 3, 2025 | clinicaltrials |
| NCT05858359 | Contextualized Neuropsychological Rehabilitation for CNS Cancer Survivors: The ImPACT Program(ImPACT) | completed | N/A | 27 | Aarhus University HospitalOTHER | 1 | Oct 3, 2025 | clinicaltrials |
| NCT06199050 | The Effect of 360° Virtual Reality Movies on Fear and Anxiety(ENGAGE) | completed | N/A | 292 | Maastricht Radiation OncologyOTHER | 1 | Oct 2, 2025 | clinicaltrials |
| NCT06439420 | CBT-I in Primary Brain Tumor Patients: Phase IIc Randomized Feasibility Pilot Trial(CBT-I in PBT) | completed | Phase 2 | 70 | Virginia Commonwealth UniversityOTHER | 1 | Oct 1, 2025 | clinicaltrials |
| NCT02245997 | Local Control With Reduced-dose Radiotherapy for High-Risk Neuroblastoma | completed | Early Phase 1 | 78 | Memorial Sloan Kettering Cancer CenterOTHER | 1 | Sep 29, 2025 | clinicaltrials |
| NCT05608395 | 11C-methionine in Diagnostics and Management of Glioblastoma Multiforme Patients (GlioMET)(GlioMET) | completed | Phase 2 | 33 | Masaryk Memorial Cancer InstituteOTHER | 1 | Sep 25, 2025 | clinicaltrials |
| NCT05270707 | HyperArc Registry Study | completed | — | 968 | Varian, a Siemens Healthineers CompanyINDUSTRY | 4 | Sep 24, 2025 | clinicaltrials |
| NCT05157594 | hPG80 (Circulating Progastrin) as a Blood Biomarker for High-grade Glial Tumors(PROGLIO) | completed | — | 30 | Centre Jean PerrinOTHER | 1 | Sep 22, 2025 | clinicaltrials |
| NCT06115824 | New-diagnosed PCNSL Treated With Methotrexate (MTX) and Orelabrutinib-based Regimen | completed | — | 136 | Huashan HospitalOTHER | 1 | Sep 16, 2025 | clinicaltrials |
| NCT01351870 | Hyperfractionated Versus Conventionally Fractionated Radiotherapy in Standard Risk Medulloblastoma (PNET4)(SIOP-PNET-4) | completed | Phase 3 | 52 | Institut CurieOTHER | 1 | Sep 15, 2025 | clinicaltrials |
| NCT01811121 | MEDICO-ECONOMIC EVALUATION OF SURGERY GUIDED BY FLUORESCENCE FOR THE OPTIMIZATION OF RESECTION OF GLIOBLASTOMAS(RESECT) | completed | Phase 3 | 170 | Hospices Civils de LyonOTHER | 1 | Sep 15, 2025 | clinicaltrials |
| NCT03107988 | NANT 2015-02: A Phase 1 Study of Lorlatinib (PF-06463922) | completed | Phase 1 | 65 | New Approaches to Neuroblastoma Therapy ConsortiumOTHER | 4 | Sep 15, 2025 | clinicaltrials |
| NCT03561870 | Olaparib in Recurrent IDH-mutant Glioma(OLAGLI) | completed | Phase 2 | 35 | Hospices Civils de LyonOTHER | 1 | Sep 12, 2025 | clinicaltrials |
| NCT04057976 | Use of DTT to Define Facial Nerve Position in Vestibular Schwannomas | completed | N/A | 38 | King's College Hospital NHS TrustOTHER | 1 | Sep 12, 2025 | clinicaltrials |
| NCT06390579 | Building Research With Artificial Intelligence in Neuro-Ophthalmology(BRAIN) | completed | — | 693 | Fondation Ophtalmologique Adolphe de RothschildNETWORK | 1 | Sep 8, 2025 | clinicaltrials |
| NCT00186888 | Study of Treatment for Patients With Cancer of the Eye -Retinoblastoma | completed | Phase 3 | 107 | St. Jude Children's Research HospitalOTHER | 1 | Sep 4, 2025 | clinicaltrials |
| NCT03050736 | Safety Study of VAL-083 and Radiotherapy in Patients With Newly Diagnosed GBM Having Unmethylated MGMT Expression | completed | Phase 2 | 29 | Kintara Therapeutics, Inc.INDUSTRY | 1 | Sep 4, 2025 | clinicaltrials |
| NCT04324450 | Memory Neuroimaging in Children, Adolescents and Young Adults Following Pediatric Cancer(IMPALA) | completed | N/A | 60 | Institut National de la Santé Et de la Recherche Médicale, FranceOTHER_GOV | 1 | Sep 4, 2025 | clinicaltrials |
| NCT01165632 | Fluorine F 18 Fluorodopa-Labeled PET Scan in Planning Surgery and Radiation Therapy in Treating Patients With Newly Diagnosed High- or Low-Grade Malignant Glioma | completed | Early Phase 1 | 24 | Mayo ClinicOTHER | 1 | Sep 2, 2025 | clinicaltrials |
| NCT02656407 | Intraoperative Functional Ultrasound(FUSIMAGINE) | completed | N/A | 23 | Institut National de la Santé Et de la Recherche Médicale, FranceOTHER_GOV | 1 | Sep 2, 2025 | clinicaltrials |
Data updated 23 days agoSource updated Dec 10, 2025source: clinicaltrials