Clinical trial · Observational
Rhabdoid Tumors Cellular Architecture by Single-cell Analyses (InnovRT-2)
Hétérogénéité Des Tumeurs Rhabdoides : Approches en " Cellules Uniques " Pour Identifier Des Cibles thérapeutiques
NCT04987476CI-TRIAL-00097557InnovRT-2completedClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The aim is to describe at the cellular level the heterogeneity of rhabdoid tumors, and identify how this diversity influences resistance to treatment.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| ATRT | Atypical Teratoid/Rhabdoid Tumor | ALIAS | 0.90 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| analyzes in singles cells | Biological | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- label
- ATRT
- description
- Children affected by an ATRT at time of surgical resection
- interventionNames
- Biological: analyzes in singles cells
Primary outcomes (1)
- measure
- Intra-tumor heterogeneity
- timeFrame
- Inclusion
- description
- Identification of cell clusters - mean expression (RPKM unit) of gene set signtaures in each bioinformatically defined cluster
Secondary outcomes (3)
- measure
- Cell clusters recurrent from one sample to the other
- timeFrame
- Inclusion
- description
- Fraction/percentage of cell clusters defined by primary outcome that are specific to each tumor and those that are shared by several or all samples
Eligibility
Eligibility (as posted)
- Sex
- All
- Maximum age
- 17 Years
Show eligibility criteria text
Inclusion Criteria: * Aged 0-17 years old * having a rhabdoid tumor according to clinical and radiological features Or likely having a rhabdoid tumor according to clinical and radiological features * surgical resection in standard care * sufficient material for both diagnosis and experimental procedures * parents' agreement
References
Publications (0)
Data not yet available
No reference posted for this study.