Cancer Family
Melanocytic Neoplasm
CI-CAN-00000026Explore in graph →
Non-malignant609 active trials13 approved drugs233 evidence items
- NCIt
- C7058
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Cancer Family
CI-CAN-00000026Explore in graph →
Genomics
26 cohorts mapped to this entity or its descendants. Each frequency is affected / profiled within one cohort; cohorts are shown separately because case selection, sequencing depth and definitions differ. By default the cohort with the most cases profiled is shown.
144 cases with simple somatic mutation data · 144 cases total · 2026-02-10 · mapped to Melanoma EXACT_IDENTIFIER
| # | Gene | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Source |
|---|---|---|---|---|---|---|
| 1 | TTN |
Cohorts mapped to a descendant (e.g. a subtype) are included because their cases belong to this entity by definition; the mapping and its match type are shown per cohort.
| 92 |
| 144 |
| 63.9% |
| cbioportal |
| 2 | MUC16 | Ssm | 86 | 144 | 59.7% | cbioportal |
| 3 | DNAH5 | Ssm | 69 | 144 | 47.9% | cbioportal |
| 4 | PCLO | Ssm | 65 | 144 | 45.1% | cbioportal |
| 5 | LRP1B | Ssm | 57 | 144 | 39.6% | cbioportal |
| 6 | BRAF | Ssm | 56 | 144 | 38.9% | cbioportal |
| 7 | DNAH6 | Ssm | 49 | 144 | 34% | cbioportal |
| 8 | MXRA5 | Ssm | 48 | 144 | 33.3% | cbioportal |
| 10 | RP1 | Ssm | 48 | 144 | 33.3% | cbioportal |
| 9 | PKHD1L1 | Ssm | 48 | 144 | 33.3% | cbioportal |
| 11 | ANK3 | Ssm | 47 | 144 | 32.6% | cbioportal |
| 12 | CSMD1 | Ssm | 47 | 144 | 32.6% | cbioportal |
| 13 | APOB | Ssm | 45 | 144 | 31.3% | cbioportal |
| 14 | DNAH7 | Ssm | 45 | 144 | 31.3% | cbioportal |
| 16 | OBSCN | Ssm | 45 | 144 | 31.3% | cbioportal |
| 15 | MGAM | Ssm | 45 | 144 | 31.3% | cbioportal |
| 19 | FSIP2 | Ssm | 43 | 144 | 29.9% | cbioportal |
| 18 | FAT4 | Ssm | 43 | 144 | 29.9% | cbioportal |
| 20 | NRAS | Ssm | 43 | 144 | 29.9% | cbioportal |
| 17 | ADGRV1 | Ssm | 43 | 144 | 29.9% | cbioportal |
| 21 | NEB | Ssm | 42 | 144 | 29.2% | cbioportal |
| 23 | CSMD2 | Ssm | 41 | 144 | 28.5% | cbioportal |
| 22 | CFAP54 | Ssm | 41 | 144 | 28.5% | cbioportal |
| 24 | MUC17 | Ssm | 41 | 144 | 28.5% | cbioportal |
| 25 | FLG | Ssm | 40 | 144 | 27.8% | cbioportal |
| 26 | HYDIN | Ssm | 40 | 144 | 27.8% | cbioportal |
| 28 | FAT3 | Ssm | 39 | 144 | 27.1% | cbioportal |
| 29 | ZFHX4 | Ssm | 39 | 144 | 27.1% | cbioportal |
| 27 | CSMD3 | Ssm | 39 | 144 | 27.1% | cbioportal |
| 30 | DNAH9 | Ssm | 38 | 144 | 26.4% | cbioportal |
Data updated 22 days agoSource updated 2026-02-10