Cancer Family
Melanocytic Neoplasm
CI-CAN-00000026Explore in graph →
Non-malignant609 active trials13 approved drugs233 evidence items
- NCIt
- C7058
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Cancer Family
CI-CAN-00000026Explore in graph →
Genomics
26 cohorts mapped to this entity or its descendants. Each frequency is affected / profiled within one cohort; cohorts are shown separately because case selection, sequencing depth and definitions differ. By default the cohort with the most cases profiled is shown.
27 cases with simple somatic mutation data · 27 cases total · 2026-02-11 · mapped to Melanoma EXACT_IDENTIFIER
| # | Gene | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Source |
|---|---|---|---|---|---|---|
| 1 | TTN | Ssm |
Cohorts mapped to a descendant (e.g. a subtype) are included because their cases belong to this entity by definition; the mapping and its match type are shown per cohort.
| 25 |
| 27 |
| 92.6% |
| cbioportal |
| 2 | MUC16 | Ssm | 23 | 27 | 85.2% | cbioportal |
| 3 | DNAH5 | Ssm | 18 | 27 | 66.7% | cbioportal |
| 5 | LRP1B | Ssm | 17 | 27 | 63% | cbioportal |
| 4 | CSMD1 | Ssm | 17 | 27 | 63% | cbioportal |
| 8 | THSD7B | Ssm | 16 | 27 | 59.3% | cbioportal |
| 7 | PCLO | Ssm | 16 | 27 | 59.3% | cbioportal |
| 6 | BRAF | Ssm | 16 | 27 | 59.3% | cbioportal |
| 9 | APOB | Ssm | 15 | 27 | 55.6% | cbioportal |
| 10 | DNAH7 | Ssm | 15 | 27 | 55.6% | cbioportal |
| 11 | HYDIN | Ssm | 15 | 27 | 55.6% | cbioportal |
| 12 | RP1 | Ssm | 15 | 27 | 55.6% | cbioportal |
| 20 | NEB | Ssm | 14 | 27 | 51.9% | cbioportal |
| 21 | OBSCN | Ssm | 14 | 27 | 51.9% | cbioportal |
| 16 | CRB1 | Ssm | 14 | 27 | 51.9% | cbioportal |
| 19 | FLG | Ssm | 14 | 27 | 51.9% | cbioportal |
| 15 | CFAP54 | Ssm | 14 | 27 | 51.9% | cbioportal |
| 18 | FAT4 | Ssm | 14 | 27 | 51.9% | cbioportal |
| 22 | WDFY4 | Ssm | 14 | 27 | 51.9% | cbioportal |
| 13 | ADGRV1 | Ssm | 14 | 27 | 51.9% | cbioportal |
| 14 | ANK3 | Ssm | 14 | 27 | 51.9% | cbioportal |
| 17 | DNAH3 | Ssm | 14 | 27 | 51.9% | cbioportal |
| 27 | TRANK1 | Ssm | 13 | 27 | 48.1% | cbioportal |
| 28 | WDR87 | Ssm | 13 | 27 | 48.1% | cbioportal |
| 25 | MUC17 | Ssm | 13 | 27 | 48.1% | cbioportal |
| 26 | SPHKAP | Ssm | 13 | 27 | 48.1% | cbioportal |
| 23 | CSMD2 | Ssm | 13 | 27 | 48.1% | cbioportal |
| 24 | DNAH9 | Ssm | 13 | 27 | 48.1% | cbioportal |
| 35 | SI | Ssm | 12 | 27 | 44.4% | cbioportal |
| 34 | PAPPA2 | Ssm | 12 | 27 | 44.4% | cbioportal |
Data updated 22 days agoSource updated 2026-02-11