Cancer
Malignant Thyroid Gland Neoplasm
CI-CAN-00003251Explore in graph →
Top-level176 active trials10 approved drugs63 evidence items
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Cancer
CI-CAN-00003251Explore in graph →
Clinical trials
790 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
Computedformula ci-trial-intel-v1 · interventional studies · entity + NCIt descendants · hover a figure for its formulaCompare cancersTerminated studies (65)
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT06475989 | Study of Targeted Therapy vs. Chemotherapy in Patients With Thyroid Cancer | recruiting | Phase 3 | 264 | ECOG-ACRIN Cancer Research GroupNETWORK | 1 | Sep 24, 2026 | clinicaltrials |
| NCT07440290 | DETERMINE Trial Treatment Arm 07: Dabrafenib in Combination With Trametinib in Adult, Paediatric and Teenage/Young Adult Patients With BRAF V600 Mutation-Positive Cancers.(DETERMINE) | recruiting | Phase 2 / Phase 3 | 30 | Cancer Research UKOTHER | 1 | Aug 17, 2026 |
| clinicaltrials |
| NCT04290663 | Systematic Radioiodine Administration Versus Decision of Radioiodine Treatment Guided by a Post-operative Work-up(INTERMEDIATE) | recruiting | Phase 3 | 368 | Centre Francois BaclesseOTHER | 1 | Jun 25, 2026 | clinicaltrials |
| NCT06851663 | Trop2-targeted immunoPET Imaging of Solid Tumors | recruiting | Phase 2 / Phase 3 | 400 | RenJi HospitalOTHER | 1 | May 29, 2026 | clinicaltrials |
| NCT01398085 | IoN- Is Ablative Radio-iodine Necessary for Low Risk Differentiated Thyroid Cancer Patients(IoN) | active not recruiting | Phase 2 / Phase 3 | 504 | University College, LondonOTHER | 1 | May 7, 2026 | clinicaltrials |
| NCT04211337 | A Study of Selpercatinib (LY3527723) in Participants With RET-Mutant Medullary Thyroid Cancer(LIBRETTO-531) | active not recruiting | Phase 3 | 291 | Loxo Oncology, Inc.INDUSTRY | 20 | Mar 19, 2026 | clinicaltrials |
| NCT03570021 | ESTIMation of the ABiLity of Prophylactic Central Compartment Neck Dissection to Modify Outcomes in Low-risk Differentiated Thyroid Cancer(ESTIMABL3) | active not recruiting | Phase 3 | 352 | Gustave Roussy, Cancer Campus, Grand ParisOTHER | 3 | Mar 6, 2026 | clinicaltrials |
| NCT06554652 | Selective Neck Dissection Versus Modified Neck Dissection in PTC | recruiting | Phase 3 | 250 | Fudan UniversityOTHER | 1 | Feb 27, 2026 | clinicaltrials |
| NCT06558981 | Adjuvant Radiotherapy in High Risk Locally Advanced DTC | recruiting | Phase 3 | 124 | Fudan UniversityOTHER | 1 | Feb 27, 2026 | clinicaltrials |
| NCT07383246 | CTR-FAPI-guided Precision Surgery for Newly Diagnosed MTC(CAST-MTC) | recruiting | Phase 3 | 150 | Cancer Institute and Hospital, Chinese Academy of Medical SciencesOTHER | 1 | Feb 3, 2026 | clinicaltrials |
| NCT06860971 | A Study of AL2846 Capsule Versus Placebo in the Treatment of Advanced Radioiodine-Refractory Differentiated Thyroid Carcinoma | recruiting | Phase 3 | 144 | Chia Tai Tianqing Pharmaceutical Group Co., Ltd.INDUSTRY | 1 | Dec 31, 2025 | clinicaltrials |
| NCT05768178 | DETERMINE Trial Treatment Arm 05: Vemurafenib in Combination With Cobimetinib in Adult Patients With BRAF Positive Cancers.(DETERMINE) | recruiting | Phase 2 / Phase 3 | 30 | Cancer Research UKOTHER | 1 | Nov 24, 2025 | clinicaltrials |
| NCT05999630 | Artificial Tears to Prevent Nasolacrimal Duct Obstruction in Patients Treated With Radioactive Iodine for Thyroid Cancer | recruiting | Phase 3 | 100 | Vanderbilt University Medical CenterOTHER | 1 | Oct 28, 2025 | clinicaltrials |
| NCT00410761 | An Efficacy Study Comparing ZD6474 to Placebo in Medullary Thyroid Cancer | completed | Phase 3 | 331 | Genzyme, a Sanofi CompanyINDUSTRY | 24 | Sep 24, 2025 | clinicaltrials |
| NCT06791005 | A Clinical Study on the Benefits of Carbon Nanoparticles Injection Time in Patients With Thyroid Cancer. | recruiting | Phase 3 | 400 | Second Affiliated Hospital of Xi'an Jiaotong UniversityOTHER | 1 | Jan 24, 2025 | clinicaltrials |
| NCT04760288 | A Study of Pralsetinib Versus Standard of Care (SOC) for Treatment of RET-Mutated Medullary Thyroid Cancer (MTC).(AcceleRET-MTC) | withdrawn | Phase 3 | 0 | Hoffmann-La RocheINDUSTRY | 1 | Jan 5, 2024 | clinicaltrials |
| NCT06082180 | A Prospective, Open-label, Multicenter, Randomized Controlled Phase III Study of Prophylactic Central Neck Dissection in Low-risk Papillary Thyroid Cancer | recruiting | Phase 3 | 1,199 | Cancer Institute and Hospital, Chinese Academy of Medical SciencesOTHER | 1 | Oct 13, 2023 | clinicaltrials |
| NCT01321554 | A Multicenter, Randomized, Double-Blind, Placebo-Controlled, Trial of Lenvatinib (E7080) in 131I-Refractory Differentiated Thyroid Cancer (DTC)(SELECT) | completed | Phase 3 | 392 | Eisai Inc.INDUSTRY | 23 | Jun 22, 2023 | clinicaltrials |
| NCT05468554 | Evaluation of Metformin Effect on the Fertility of Women Treated With 131I for Thyroid Cancer(METHYR) | unknown | Phase 3 | 160 | Medical University of BialystokOTHER | 1 | Oct 19, 2022 | clinicaltrials |
| NCT00704730 | Efficacy of XL184 (Cabozantinib) in Advanced Medullary Thyroid Cancer(EXAM) | completed | Phase 3 | 330 | ExelixisINDUSTRY | 24 | Apr 20, 2021 | clinicaltrials |
| NCT02586350 | Study of Anlotinib in Patients With Medullary Thyroid Carcinoma(ALTER01031) | completed | Phase 2 / Phase 3 | 91 | Chia Tai Tianqing Pharmaceutical Group Co., Ltd.INDUSTRY | 1 | May 21, 2019 | clinicaltrials |
| NCT01083550 | Decision Making on Radioactive Iodine Treatment for Papillary Thyroid Cancer | completed | Phase 2 / Phase 3 | 74 | University Health Network, TorontoOTHER | 1 | Nov 29, 2016 | clinicaltrials |
| NCT00795782 | Prophylactic Central Lymph Node Dissection in Papillary Thyroid Microcarcinoma | completed | Phase 3 | 258 | Samsung Medical CenterOTHER | 1 | Apr 15, 2016 | clinicaltrials |
| NCT00507429 | Study of Combretastatin and Paclitaxel/Carboplatin in the Treatment of Anaplastic Thyroid Cancer(FACT) | terminated | Phase 2 / Phase 3 | 80 | Mateon TherapeuticsINDUSTRY | 12 | Jun 9, 2014 | clinicaltrials |
| NCT01701349 | Fosbretabulin or Placebo in Combination With Carboplatin/Paclitaxel in Anaplastic Thyroid Cancer(FACT2) | withdrawn | Phase 3 | 0 | Mateon TherapeuticsINDUSTRY | 0 | May 1, 2014 | clinicaltrials |
| NCT01616316 | Efficacy of Subfascial Approach in Thyroidectomy to Quality of Life in Thyroid Disease Patients | completed | Phase 2 / Phase 3 | 86 | Samsung Medical CenterOTHER | 1 | Jun 11, 2012 | clinicaltrials |
| NCT01126060 | Efficacy of Fibrin Sealant to Reduce the Amount of Post-thyroidectomy Drain | completed | Phase 3 | 78 | Samsung Medical CenterOTHER | 1 | Dec 19, 2011 | clinicaltrials |
| NCT01373736 | 123I-MIBG Scintigraphy in Patients Being Evaluated for Neuroendocrine Tumors | unknown | Phase 3 | — | Vancouver Coastal HealthOTHER_GOV | 1 | Jun 15, 2011 | clinicaltrials |
| NCT00794053 | The Usefulness of Staining Lymph Nodes During Operations for Cancer Thyroid in Detecting the Nodes That Have Cancer | completed | Phase 3 | 45 | University of AlexandriaOTHER | 1 | Jul 15, 2009 | clinicaltrials |
| NCT00435851 | Medico-Economic Comparison of Four Strategies of Radioiodine Ablation in Thyroid Carcinoma Patients(Estimabl) | unknown | Phase 3 | 950 | Gustave Roussy, Cancer Campus, Grand ParisOTHER | 1 | Feb 19, 2007 | clinicaltrials |
Data updated 4 days agoSource updated Sep 24, 2026source: clinicaltrials