Cancer
Malignant Thyroid Gland Neoplasm
CI-CAN-00003251Explore in graph →
Top-level176 active trials10 approved drugs63 evidence items
Loading cancer entity…
Loading cancer entity…
Cancer
CI-CAN-00003251Explore in graph →
Clinical trials
790 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
Computedformula ci-trial-intel-v1 · interventional studies · entity + NCIt descendants · hover a figure for its formulaCompare cancersTerminated studies (65)
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT04459273 | Prospective Exploratory Study of FAPi PET/CT With Histopathology Validation in Patients With Various Cancers(FAPI PET RDRC) | active not recruiting | Phase 1 | 26 | Jonsson Comprehensive Cancer CenterOTHER | 1 | Feb 5, 2026 | clinicaltrials |
| NCT04916990 | Improving Care for Rural Patients With Solid Tumors | recruiting | N/A | 320 | University of Colorado, DenverOTHER | 1 | Feb 5, 2026 | clinicaltrials |
| NCT06235814 | Molecular Analysis for Precision Surgery in Thyroid Cancer Trial(MAPS) | completed | N/A | 2 | University of California, Los AngelesOTHER | 1 | Feb 5, 2026 | clinicaltrials |
| NCT07389512 | Pharmaceutical Management in Targeted Radioligand Therapy(PharmTRT) | recruiting | — | 600 | Hospices Civils de LyonOTHER | 1 | Feb 5, 2026 | clinicaltrials |
| NCT06984991 | Factors Influencing Inadequacy in Rapid Onsite Evaluation of Ultrasound Guided Fine Needle Aspiration (FNA) Samples of Thyroid Nodules(FNA inadequacy) | recruiting | N/A | 160 | Assiut UniversityOTHER | 1 | Feb 3, 2026 | clinicaltrials |
| NCT07383246 | CTR-FAPI-guided Precision Surgery for Newly Diagnosed MTC(CAST-MTC) | recruiting | Phase 3 | 150 | Cancer Institute and Hospital, Chinese Academy of Medical SciencesOTHER | 1 | Feb 3, 2026 | clinicaltrials |
| NCT06440850 | Vemurafenib and Cobimetinib for the Treatment of Patients With High Risk Differentiated Thyroid Carcinoma With BRAFV600E Mutation | recruiting | Phase 2 | 21 | City of Hope Medical CenterOTHER | 1 | Feb 2, 2026 | clinicaltrials |
| NCT06639191 | [177Lu]Lu-AKIR001 First-in-human Study(AKIR001) | recruiting | Early Phase 1 | 15 | Karolinska University HospitalOTHER | 1 | Jan 30, 2026 | clinicaltrials |
| NCT04495985 | CASE 1320: RAI Uptake and Serum Prolactin in Thyroid Cancer | active not recruiting | — | 39 | The Cleveland ClinicOTHER | 1 | Jan 28, 2026 | clinicaltrials |
| NCT05014698 | IDEntification of New Predisposition Genes in Differentiated THYroid Cancer(IDENTHY-K) | terminated | N/A | 34 | Nantes University HospitalOTHER | 1 | Jan 28, 2026 | clinicaltrials |
| NCT07370675 | Active Surveillance for Bethesda IV Thyroid Nodules | recruiting | N/A | 165 | Christian Grønhøj LarsenOTHER | 1 | Jan 27, 2026 | clinicaltrials |
| NCT04593277 | Interactive Survivorship Program for the Improvement of Healthcare Resources in Adolescent and Young Adult Cancer Survivors, INSPIRE-AYA Study | completed | N/A | 549 | Fred Hutchinson Cancer CenterOTHER | 1 | Jan 23, 2026 | clinicaltrials |
| NCT07357571 | Preoperative Prediction of Lymph Node Metastasis in T1N0M0 Papillary Thyroid Carcinoma by Using Contrast-enhanced Ultrasound | recruiting | — | 600 | Sun Yat-Sen Memorial Hospital of Sun Yat-Sen UniversityOTHER | 1 | Jan 22, 2026 | clinicaltrials |
| NCT07359586 | Laryngopharyngeal Injury After Endotracheal Intubation Under General Anesthesia | recruiting | — | 1,200 | Zhejiang UniversityOTHER | 1 | Jan 22, 2026 | clinicaltrials |
| NCT07354698 | Application of Mitoxantrone Hydrochloride Injection in Transoral Robotic Thyroid Cancer Surgery(MHI) | not yet recruiting | Phase 4 | 114 | Daping Hospital and the Research Institute of Surgery of the Third Military Medical UniversityOTHER | 1 | Jan 21, 2026 | clinicaltrials |
| NCT05366881 | cfDNA Assay Prospective Observational Validation for Early Cancer Detection and Minimal Residual Disease(CAMPERR) | recruiting | — | 7,000 | Adela, IncINDUSTRY | 1 | Jan 20, 2026 | clinicaltrials |
| NCT06133374 | Concordance of Molecular Classification Based on Fine Needle Biopsy (FNB) and Surgical Samples | recruiting | — | 130 | University of CalgaryOTHER | 1 | Jan 15, 2026 | clinicaltrials |
| NCT06980103 | Use of a Decision Aid to Resolve Uncertainty About Radioactive Iodine Treatment in Patients With Intermediate Risk Thyroid Cancer | recruiting | N/A | 408 | Georgetown UniversityOTHER | 1 | Jan 8, 2026 | clinicaltrials |
| NCT03899792 | A Study of Oral LOXO-292 (Selpercatinib) in Pediatric Participants With Advanced Solid or Primary Central Nervous System (CNS) Tumors(LIBRETTO-121) | active not recruiting | Phase 1 / Phase 2 | 36 | Eli Lilly and CompanyINDUSTRY | 11 | Jan 6, 2026 | clinicaltrials |
| NCT07314255 | The Role of Trop2 in Radioactive Iodine-131 Therapy Sensitivity in Papillary Thyroid Carcinoma(ZL2025) | active not recruiting | — | 60 | Jiangxi Provincial Cancer HospitalOTHER | 1 | Jan 2, 2026 | clinicaltrials |
| NCT06860971 | A Study of AL2846 Capsule Versus Placebo in the Treatment of Advanced Radioiodine-Refractory Differentiated Thyroid Carcinoma | recruiting | Phase 3 | 144 | Chia Tai Tianqing Pharmaceutical Group Co., Ltd.INDUSTRY | 1 | Dec 31, 2025 | clinicaltrials |
| NCT07298187 | The Effect of Head Position on the Optik Nerve Sheath Diameter in Patients During Thyroid Surgery | completed | — | 49 | Istanbul University - CerrahpasaOTHER | 1 | Dec 23, 2025 | clinicaltrials |
| NCT07299318 | Multimodal Deep Learning for Lymph Node Metastasis in Thyroid Cancer | not yet recruiting | — | 3,200 | West China HospitalOTHER | 1 | Dec 23, 2025 | clinicaltrials |
| NCT07296575 | Ultrasound Large-scale Model in Thyroid Field: A Multi-center Study on Medical-Engineering Integration | active not recruiting | — | 2,000 | Second Affiliated Hospital of Nanchang UniversityOTHER | 1 | Dec 22, 2025 | clinicaltrials |
| NCT07274605 | Comparing the Therapeutic Efficacy of Extended Isthmusectomy Versus Total Thyroidectomy for Isthmus Tumors of the Thyroid | not yet recruiting | N/A | 520 | Second Affiliated Hospital, Zhejiang University, School of MedicineOTHER | 1 | Dec 10, 2025 | clinicaltrials |
| NCT07274670 | Superficial Cervical Plexus Block With Dexmedetomidine Versus Without Adjuvant in Thyroid Surgery(BPSS-DEX) | completed | N/A | 58 | Udayana UniversityOTHER | 1 | Dec 10, 2025 | clinicaltrials |
| NCT05280379 | Trained Immunity in Thyroid Carcinoma and Colon Carcinoma | completed | — | 33 | Radboud University Medical CenterOTHER | 1 | Dec 9, 2025 | clinicaltrials |
| NCT06623578 | Comparative Study of Transaxillary Robotic Thyroidectomy With MRND Versus Conventional Open Surgery in N1b PTC | recruiting | N/A | 876 | Sun Yat-Sen Memorial Hospital of Sun Yat-Sen UniversityOTHER | 1 | Dec 3, 2025 | clinicaltrials |
| NCT04624477 | Active Surveillance and Surgery Outcomes in Low Risk Papillary Thyroid Cancer | active not recruiting | — | 450 | University Health Network, TorontoOTHER | 1 | Nov 28, 2025 | clinicaltrials |
| NCT07252661 | Study of ACC-1898 in Adult Participants With Advanced Solid Tumors | not yet recruiting | Phase 1 | 40 | AccSalus Biosciences, Inc.INDUSTRY | 0 | Nov 28, 2025 | clinicaltrials |
| NCT03271892 | Deciding on Active Surveillance or Surgery for Primary Management of Low Risk Papillary Thyroid Cancer(AS-PTC) | active not recruiting | — | 200 | University Health Network, TorontoOTHER | 1 | Nov 26, 2025 | clinicaltrials |
| NCT05768178 | DETERMINE Trial Treatment Arm 05: Vemurafenib in Combination With Cobimetinib in Adult Patients With BRAF Positive Cancers.(DETERMINE) | recruiting | Phase 2 / Phase 3 | 30 | Cancer Research UKOTHER | 1 | Nov 24, 2025 | clinicaltrials |
| NCT05668585 | A Study to Characterize the Safety, Tolerability, and Preliminary Efficacy of CFT1946 as Monotherapy and Combination Therapy in Subjects With BRAF V600 Mutant Solid Tumors | completed | Phase 1 | 89 | C4 Therapeutics, Inc.INDUSTRY | 5 | Nov 21, 2025 | clinicaltrials |
| NCT07235553 | Non-inferiority Investigation to Evaluate the Efficacy and Safety of the Ultrasonic Surgical System | completed | N/A | 136 | Ezisurg Medical Co. Ltd.OTHER | 1 | Nov 19, 2025 | clinicaltrials |
| NCT07235566 | MRG003 and Pucotenlimab to Treat Locally Advanced or Metastatic ATC/PDTC | recruiting | Phase 2 | 60 | Fudan UniversityOTHER | 1 | Nov 19, 2025 | clinicaltrials |
| NCT05024929 | Targeted Therapy to Increase RAI Uptake in Metastatic DTC | recruiting | — | 32 | Children's Hospital of PhiladelphiaOTHER | 2 | Nov 14, 2025 | clinicaltrials |
| NCT05783323 | Larotrectinib to Enhance RAI Avidity in Differentiated Thyroid Cancer | recruiting | Phase 2 | 13 | Children's Hospital of PhiladelphiaOTHER | 1 | Nov 14, 2025 | clinicaltrials |
| NCT04463719 | AIM2: Adequate Selection of Patients for Thyroid Biopsy: Evaluation of a Shared Decision Making Conversation Aid | completed | N/A | 107 | University of FloridaOTHER | 1 | Nov 10, 2025 | clinicaltrials |
| NCT05999630 | Artificial Tears to Prevent Nasolacrimal Duct Obstruction in Patients Treated With Radioactive Iodine for Thyroid Cancer | recruiting | Phase 3 | 100 | Vanderbilt University Medical CenterOTHER | 1 | Oct 28, 2025 | clinicaltrials |
| NCT03517579 | Personalized Treatment in Thyroid Disorders | recruiting | N/A | 10 | Johns Hopkins UniversityOTHER | 1 | Oct 15, 2025 | clinicaltrials |
| NCT00673010 | Lesion Dosimetry With 124-Iodine in Metastatic Thyroid Carcinoma | completed | Phase 1 | 20 | Memorial Sloan Kettering Cancer CenterOTHER | 1 | Oct 9, 2025 | clinicaltrials |
| NCT04136912 | 3-D Super Resolution Ultrasound Microvascular Imaging | terminated | Phase 2 | 27 | UNC Lineberger Comprehensive Cancer CenterOTHER | 1 | Oct 6, 2025 | clinicaltrials |
| NCT06222606 | Surgery for Thyroid Cancer With or Without Autofluorescence to Prevent Hypoparathyroidism | recruiting | N/A | 160 | Aarhus University HospitalOTHER | 1 | Oct 6, 2025 | clinicaltrials |
| NCT01496313 | To Compare The Effects Of Two Doses Of Vandetanib In Patients With Advanced Medullary Thyroid Cancer | completed | Phase 4 | 81 | SanofiINDUSTRY | 9 | Oct 3, 2025 | clinicaltrials |
| NCT04985604 | Tovorafenib (DAY101) Monotherapy for Patients With Melanoma and Other Solid Tumors | terminated | Phase 2 | 23 | Day One Biopharmaceuticals, Inc.INDUSTRY | 7 | Oct 2, 2025 | clinicaltrials |
| NCT05774535 | Prospective, Observational Study on the Carotid Intima-media Thickness in Patients Undergoing Thyroid Surgery(TIROVASC) | withdrawn | — | 0 | Istituto Auxologico ItalianoOTHER | 1 | Oct 2, 2025 | clinicaltrials |
| NCT00410761 | An Efficacy Study Comparing ZD6474 to Placebo in Medullary Thyroid Cancer | completed | Phase 3 | 331 | Genzyme, a Sanofi CompanyINDUSTRY | 24 | Sep 24, 2025 | clinicaltrials |
| NCT02628067 | Study of Pembrolizumab (MK-3475) in Participants With Advanced Solid Tumors (MK-3475-158/KEYNOTE-158) | active not recruiting | Phase 2 | 1,609 | Merck Sharp & Dohme LLCINDUSTRY | 0 | Sep 22, 2025 | clinicaltrials |
| NCT05851560 | Prospective Comparison of the Effect on Antiadhesive Barriers During Thyroid Surgery | completed | Phase 1 | 45 | National Taiwan University HospitalOTHER | 1 | Sep 19, 2025 | clinicaltrials |
| NCT06270082 | Study of IK-595 in RAS- or RAF-altered Advanced Tumors | terminated | Phase 1 | 75 | Ikena OncologyINDUSTRY | 1 | Sep 19, 2025 | clinicaltrials |
Data updated 23 days agoSource updated Feb 5, 2026source: clinicaltrials