Cancer Family
Malignant Mesothelioma
CI-CAN-00000240Explore in graph →
Top-level96 active trials4 approved drugs11 evidence items
- NCIt
- C4456
- ICD-10
- C45
- DOID
- 1790
- MeSH
- D000086002
- MeSH
- D008654
- Other
- 1 more code
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Cancer Family
CI-CAN-00000240Explore in graph →
Clinical trials
478 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
Computedformula ci-trial-intel-v1 · interventional studies · entity + NCIt descendants · hover a figure for its formulaCompare cancersTerminated studies (81)
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT01592383 | Erlotinib Hydrochloride in Treating Patients With Malignant Peritoneal Mesothelioma | completed | Phase 2 | 2 | University of ChicagoOTHER | 1 | Oct 16, 2018 | clinicaltrials |
| NCT02397928 | Safety and Efficacy of TTFields (150 kHz) Concomitant With Pemetrexed and Cisplatin or Carboplatin in Malignant Pleural Mesothelioma (STELLAR) | completed | Phase 2 | 82 | NovoCure Ltd.INDUSTRY | 7 | Sep 25, 2018 | clinicaltrials |
| NCT00458913 | Bortezomib and Cisplatin as First-Line Therapy in Treating Patients With Malignant Mesothelioma | completed | Phase 2 | 82 | European Organisation for Research and Treatment of Cancer - EORTCNETWORK | 1 | Jul 12, 2018 | clinicaltrials |
| NCT00365053 | PXD101 as Second-Line Therapy in Treating Patients With Malignant Mesothelioma of the Chest That Cannot Be Removed By Surgery | completed | Phase 2 | 13 | National Cancer Institute (NCI)NIH | 1 | Jun 7, 2018 | clinicaltrials |
| NCT01627795 | Safety and Efficacy of Oshadi D and Oshadi R for Malignant Mesothelioma Treatment | suspended | Phase 1 / Phase 2 | 17 | Oshadi Drug AdministrationINDUSTRY | 1 | Apr 18, 2018 | clinicaltrials |
| NCT02758587 | Study of FAK (Defactinib) and PD-1 (Pembrolizumab) Inhibition in Advanced Solid Malignancies (FAK-PD1) | unknown | Phase 1 / Phase 2 | 59 | NHS Greater Glasgow and ClydeOTHER | 1 | Mar 19, 2018 | clinicaltrials |
| NCT00243074 | S0509 - AZD2171 in Treating Patients With Malignant Pleural Mesothelioma That Cannot Be Removed By Surgery | completed | Phase 2 | 54 | National Cancer Institute (NCI)NIH | 1 | Jan 23, 2018 | clinicaltrials |
| NCT02497508 | Nivolumab in Patients With Recurrent Malignant Mesothelioma(NivoMes) | completed | Phase 2 | 33 | The Netherlands Cancer InstituteOTHER | 0 | Sep 14, 2017 | clinicaltrials |
| NCT01721018 | Intrapleural Administration of HSV1716 to Treat Patients With Malignant Pleural Mesothelioma.(1716-12) | completed | Phase 1 / Phase 2 | 12 | Virttu Biologics LimitedINDUSTRY | 1 | Jun 9, 2017 | clinicaltrials |
| NCT01204203 | Pilot Study of Bisphosphonate Therapy (Zoledronic Acid) in Patients With Malignant Mesothelioma (UAB 0901)(UAB0901) | completed | Phase 2 | 8 | University of Alabama at BirminghamOTHER | 1 | May 24, 2017 | clinicaltrials |
| NCT00895648 | Pemetrexed (ALIMTA) Plus Cisplatin Followed by Surgery and Radiation Therapy for Mesothelioma | terminated | Phase 2 | 6 | University Health Network, TorontoOTHER | 1 | May 4, 2017 | clinicaltrials |
| NCT00604461 | Carboplatin, Bevacizumab and Pemetrexed in the First-Line Treatment of Patients With Malignant Pleural Mesothelioma (MPM) | terminated | Phase 1 / Phase 2 | 13 | H. Lee Moffitt Cancer Center and Research InstituteOTHER | 1 | Mar 23, 2017 | clinicaltrials |
| NCT01869023 | Phase II Study of Six Hours Low Dose Gemcitabine Plus Cisplatin in the Treatment for Advanced Pleural Mesothelioma | unknown | Phase 2 | 26 | Instituto Nacional de Cancerologia de MexicoOTHER | 1 | Mar 3, 2017 | clinicaltrials |
| NCT01211275 | Standard Chemotherapy With of Without Axitinib in Malignant Mesothelioma(N08CPA) | completed | Phase 1 / Phase 2 | 32 | The Netherlands Cancer InstituteOTHER | 1 | Feb 28, 2017 | clinicaltrials |
| NCT01870609 | Placebo Controlled Study of VS-6063 in Subjects With Malignant Pleural Mesothelioma(COMMAND) | terminated | Phase 2 | 344 | Verastem, Inc.INDUSTRY | 15 | Jan 30, 2017 | clinicaltrials |
| NCT00017186 | Gemcitabine and Epirubicin in Treating Patients With Malignant Mesothelioma | completed | Phase 2 | 69 | Alliance for Clinical Trials in OncologyOTHER | 1 | Dec 7, 2016 | clinicaltrials |
| NCT02661100 | A Trial of CDX-1401 in Combination With Poly-ICLC and Pembrolizumab, in Previously Treated Advanced Solid Tumor Patients | withdrawn | Phase 1 / Phase 2 | 0 | Case Comprehensive Cancer CenterOTHER | 0 | Dec 7, 2016 | clinicaltrials |
| NCT02755675 | uPAR-PET for Prognostication in Patients With Non-small Cell Lung Cancer, Malignant Pleural Mesothelioma and Large Cell Neuroendocrine Carcinoma of the Lung | unknown | Phase 2 | 120 | Rigshospitalet, DenmarkOTHER | 1 | Nov 21, 2016 | clinicaltrials |
| NCT01861301 | Tivantinib in Treating Patients With Previously Treated Malignant Mesothelioma | terminated | Phase 2 | 18 | National Cancer Institute (NCI)NIH | 1 | Oct 24, 2016 | clinicaltrials |
| NCT00597116 | An Efficacy and Safety Study With Vandetanib to Treat Inoperable or Relapsed Malignant Mesothelioma | terminated | Phase 2 | 25 | Genzyme, a Sanofi CompanyINDUSTRY | 2 | Oct 10, 2016 | clinicaltrials |
| NCT00165503 | Pleurectomy/Decortication With Intraoperative Intrathoracic/Intraperitoneal Heated Cisplatin With Sodium Thiosulfate | terminated | Phase 2 | 16 | Dana-Farber Cancer InstituteOTHER | 1 | Sep 9, 2016 | clinicaltrials |
| NCT00509041 | Dasatinib in Treating Patients With Previously Treated Malignant Mesothelioma | completed | Phase 2 | 46 | Alliance for Clinical Trials in OncologyOTHER | 1 | Aug 11, 2016 | clinicaltrials |
| NCT00004183 | Capecitabine in Treating Patients With Malignant Mesothelioma | completed | Phase 2 | 27 | Alliance for Clinical Trials in OncologyOTHER | 1 | Jul 14, 2016 | clinicaltrials |
| NCT00053885 | PTK787/ZK 222584 in Treating Patients With Unresectable Malignant Mesothelioma | completed | Phase 2 | 47 | Alliance for Clinical Trials in OncologyOTHER | 1 | Jul 1, 2016 | clinicaltrials |
| NCT00469196 | Tomotherapy Treatment for Mesothelioma | completed | Phase 2 | 18 | AHS Cancer Control AlbertaOTHER | 1 | Apr 6, 2016 | clinicaltrials |
| NCT00004547 | Treatment of Peritoneal Cancer With Surgery, Perfused Heated Cisplatin and Chemotherapy | completed | Phase 2 | 188 | National Cancer Institute (NCI)NIH | 1 | Nov 18, 2015 | clinicaltrials |
| NCT01769547 | A Phase II Study of Single-agent DOVitinib in Advanced Malignant PlEural Mesothelioma Which Has Progressed Following Prior Platinum-Antifolate Chemotherapy(DOVE-M) | terminated | Phase 2 | 12 | Ontario Clinical Oncology Group (OCOG)OTHER | 1 | Sep 17, 2015 | clinicaltrials |
| NCT02497053 | Four Versus Six Cycles of Pemetrexed/Platinum for MPM | unknown | Phase 2 | 70 | Ain Shams UniversityOTHER | 1 | Jul 14, 2015 | clinicaltrials |
| NCT01024946 | Everolimus (RAD001) for the Treatment of Malignant Pleural Mesothelioma With Merlin/NF2 Loss as a Biomarker to Predict Sensitivity | completed | Phase 2 | 11 | Memorial Sloan Kettering Cancer CenterOTHER | 1 | May 12, 2015 | clinicaltrials |
| NCT00027508 | Ecteinascidin 743 in Treating Patients With Malignant Mesothelioma | terminated | Phase 2 | — | PharmaMarINDUSTRY | 1 | Feb 24, 2015 | clinicaltrials |
| NCT00459862 | Pazopanib in Treating Patients With Malignant Pleural Mesothelioma | completed | Phase 2 | 34 | National Cancer Institute (NCI)NIH | 1 | Feb 24, 2015 | clinicaltrials |
| NCT00634205 | Phase II Study of Valproate and Doxorubicin in Malignant Mesothelioma | completed | Phase 2 | 45 | European Lung Cancer Working PartyOTHER | 2 | Feb 12, 2015 | clinicaltrials |
| NCT00513877 | Bortezomib in Treating Patients With Malignant Pleural Mesothelioma | completed | Phase 2 | 33 | Cancer Trials IrelandNETWORK | 4 | Dec 31, 2014 | clinicaltrials |
| NCT01279967 | A Clinical Trial of ADI-PEG 20TM in Patients With Malignant Pleural Mesothelioma(ADAM) | unknown | Phase 2 | 70 | Barts & The London NHS TrustOTHER | 1 | Nov 20, 2014 | clinicaltrials |
| NCT00309946 | Cediranib Maleate in Treating Patients With Malignant Mesothelioma That Cannot Be Removed By Surgery | completed | Phase 2 | 51 | National Cancer Institute (NCI)NIH | 1 | Jul 31, 2014 | clinicaltrials |
| NCT00392444 | Sunitinib in Treating Patients With Advanced Malignant Pleural Mesothelioma | completed | Phase 2 | 39 | National Cancer Institute (NCI)NIH | 1 | May 21, 2014 | clinicaltrials |
| NCT00668499 | A Study of VEGF-Antisense Oligonucleotide in Combination With Pemetrexed and Cisplatin for the Treatment of Advanced Malignant Mesothelioma | withdrawn | Phase 1 / Phase 2 | 0 | University of Southern CaliforniaOTHER | 1 | May 21, 2014 | clinicaltrials |
| NCT00165516 | Extrapleural Pneumonectomy With Intraoperative Intrathoracic/Intraperitoneal Heated Cisplatin With Amifostine and Sodium Thiosulfate | completed | Phase 2 | 85 | Dana-Farber Cancer InstituteOTHER | 1 | Mar 27, 2014 | clinicaltrials |
| NCT00027703 | Combination Chemotherapy With or Without Bevacizumab in Treating Patients With Malignant Mesothelioma | completed | Phase 2 | 106 | National Cancer Institute (NCI)NIH | 1 | Feb 11, 2014 | clinicaltrials |
| NCT00024271 | Surgery, Chemotherapy, and Radiation Therapy in Treating Patients With Peritoneal Cancer | unknown | Phase 2 | — | Herbert Irving Comprehensive Cancer CenterOTHER | 1 | Jan 6, 2014 | clinicaltrials |
| NCT00002465 | High-Dose Megestrol in Treating Patients With Metastatic Breast Cancer, Endometrial Cancer, or Mesothelioma | unknown | Phase 1 / Phase 2 | — | St. Vincent Medical Center - Los AngelesOTHER | 1 | Nov 6, 2013 | clinicaltrials |
| NCT00030459 | Palliative Therapy With or Without Chemotherapy in Treating Patients With Malignant Mesothelioma | unknown | Phase 2 | — | British Thoracic SocietyOTHER | 1 | Aug 7, 2013 | clinicaltrials |
| NCT01105390 | AMG 102, Pemetrexed Disodium, and Cisplatin in Treating Patients With Malignant Pleural Mesothelioma | withdrawn | Phase 2 | 0 | National Cancer Institute (NCI)NIH | 0 | Aug 2, 2013 | clinicaltrials |
| NCT00002475 | Cyclophosphamide Plus Vaccine Therapy in Treating Patients With Advanced Cancer | completed | Phase 2 | 40 | St. Vincent Medical Center - Los AngelesOTHER | 1 | Jul 10, 2013 | clinicaltrials |
| NCT00002608 | Combination Chemotherapy and Tamoxifen in Treating Patients With Solid Tumors | completed | Phase 2 | 30 | Ottawa Regional Cancer CentreOTHER | 1 | Jul 10, 2013 | clinicaltrials |
| NCT00062283 | Alanosine in Treating Patients With Cancer | completed | Phase 2 | — | Memorial Sloan Kettering Cancer CenterOTHER | 1 | Jun 26, 2013 | clinicaltrials |
| NCT00107432 | Sorafenib Tosylate in Treating Patients With Malignant Mesothelioma. | completed | Phase 2 | 44 | National Cancer Institute (NCI)NIH | 1 | Jun 5, 2013 | clinicaltrials |
| NCT00006014 | SU5416 in Treating Patients With Malignant Mesothelioma | completed | Phase 2 | 45 | National Cancer Institute (NCI)NIH | 1 | Jun 3, 2013 | clinicaltrials |
| NCT01569919 | A Phase II Trial to Assess TroVax® Plus Chemotherapy in Patients With Malignant Pleural Mesothelioma(SKOPOS) | unknown | Phase 2 | 26 | Wales Cancer Trials UnitOTHER | 1 | Mar 12, 2013 | clinicaltrials |
| NCT00039182 | Erlotinib in Treating Patients With Malignant Mesothelioma of the Lung | completed | Phase 2 | 55 | National Cancer Institute (NCI)NIH | 1 | Jan 24, 2013 | clinicaltrials |
Data updated 22 days agoSource updated Oct 16, 2018source: clinicaltrials