Cancer Family
Malignant Mesothelioma
CI-CAN-00000240Explore in graph →
Top-level96 active trials4 approved drugs11 evidence items
- NCIt
- C4456
- ICD-10
- C45
- DOID
- 1790
- MeSH
- D000086002
- MeSH
- D008654
- Other
- 1 more code
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Cancer Family
CI-CAN-00000240Explore in graph →
Clinical trials
478 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
Computedformula ci-trial-intel-v1 · interventional studies · entity + NCIt descendants · hover a figure for its formulaCompare cancersTerminated studies (81)
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT03048474 | Ipilimumab and Nivolumab in the Treatment of Malignant Pleural Mesothelioma(INITIATE) | completed | Phase 2 | 36 | The Netherlands Cancer InstituteOTHER | 1 | Jan 20, 2021 | clinicaltrials |
| NCT02610140 | Phase II Anetumab Ravtansine as 2nd Line Treatment for Malignant Pleural Mesothelioma (MPM) | completed | Phase 2 | 248 | BayerINDUSTRY | 14 | Nov 4, 2020 | clinicaltrials |
| NCT00295503 | Cisplatin, Pemetrexed and Bevacizumab for Untreated Malignant Mesothelioma | completed | Phase 2 | 53 | University of Texas Southwestern Medical CenterOTHER | 1 | Oct 20, 2020 | clinicaltrials |
| NCT03177668 | Clinical Study of YS110 in Patients With Malignant Pleural Mesothelioma | completed | Phase 1 / Phase 2 | 40 | Kissei Pharmaceutical Co., Ltd.INDUSTRY | 1 | Sep 25, 2020 | clinicaltrials |
| NCT00024076 | Radiofrequency Ablation in Treating Patients With Refractory or Advanced Lung Cancer | completed | Phase 2 | 30 | Jonsson Comprehensive Cancer CenterOTHER | 1 | Aug 3, 2020 | clinicaltrials |
| NCT02151448 | αDC1 Vaccine + Chemokine Modulatory Regimen (CKM) as Adjuvant Treatment of Peritoneal Surface Malignancies | completed | Phase 1 / Phase 2 | 64 | David BartlettOTHER | 1 | Jul 20, 2020 | clinicaltrials |
| NCT01112293 | Anti-TGF Monoclonal Antibody (GC1008) in Relapsed Malignant Pleural Mesothelioma | completed | Phase 2 | 14 | Abramson Cancer Center at Penn MedicineOTHER | 1 | Apr 10, 2020 | clinicaltrials |
| NCT00770120 | S0722: Everolimus in Treating Patients With Pleural Malignant Mesothelioma That Cannot Be Removed By Surgery | completed | Phase 2 | 61 | SWOG Cancer Research NetworkNETWORK | 1 | Mar 6, 2020 | clinicaltrials |
| NCT02194231 | ATREUS - Phase II Study on the Activity of Trabectedin in Patients With Malignant Pleural Mesothelioma (MPM)(ATREUS) | completed | Phase 2 | 145 | Mario Negri Institute for Pharmacological ResearchOTHER | 1 | Jan 23, 2020 | clinicaltrials |
| NCT00859469 | Eloxatin® Plus Gemcitabine Chemotherapy for Mesothelioma | completed | Phase 2 | 29 | Columbia UniversityOTHER | 1 | Oct 30, 2019 | clinicaltrials |
| NCT01362790 | SS1P and Pentostatin Plus Cyclophosphamide for Mesothelioma | completed | Phase 1 / Phase 2 | 55 | National Cancer Institute (NCI)NIH | 1 | Jun 6, 2019 | clinicaltrials |
| NCT00334594 | Pemetrexed Disodium and Cisplatin Followed by Surgery With or Without Radiation Therapy in Treating Patients With Malignant Pleural Mesothelioma | completed | Phase 2 | 153 | Swiss Cancer InstituteOTHER | 2 | May 15, 2019 | clinicaltrials |
| NCT00484276 | Study of NGR-hTNF as Single Agent in Patients Affected by Advanced or Metastatic Malignant Pleural Mesothelioma(NGR010) | completed | Phase 2 | 57 | AGC Biologics S.p.A.INDUSTRY | 1 | Jan 16, 2019 | clinicaltrials |
| NCT01358084 | Phase II Study of NGR-hTNF Versus Placebo as Maintenance Treatment in Patients With Advanced MPM(NGR019) | completed | Phase 2 | 137 | AGC Biologics S.p.A.INDUSTRY | 3 | Jan 15, 2019 | clinicaltrials |
| NCT02599194 | 18F-FSPG PET/CT for Cancer Patients on Therapy | completed | Phase 2 | 7 | Andrei IagaruOTHER | 1 | Jan 3, 2019 | clinicaltrials |
| NCT01592383 | Erlotinib Hydrochloride in Treating Patients With Malignant Peritoneal Mesothelioma | completed | Phase 2 | 2 | University of ChicagoOTHER | 1 | Oct 16, 2018 | clinicaltrials |
| NCT02397928 | Safety and Efficacy of TTFields (150 kHz) Concomitant With Pemetrexed and Cisplatin or Carboplatin in Malignant Pleural Mesothelioma (STELLAR) | completed | Phase 2 | 82 | NovoCure Ltd.INDUSTRY | 7 | Sep 25, 2018 | clinicaltrials |
| NCT00458913 | Bortezomib and Cisplatin as First-Line Therapy in Treating Patients With Malignant Mesothelioma | completed | Phase 2 | 82 | European Organisation for Research and Treatment of Cancer - EORTCNETWORK | 1 | Jul 12, 2018 | clinicaltrials |
| NCT00365053 | PXD101 as Second-Line Therapy in Treating Patients With Malignant Mesothelioma of the Chest That Cannot Be Removed By Surgery | completed | Phase 2 | 13 | National Cancer Institute (NCI)NIH | 1 | Jun 7, 2018 | clinicaltrials |
| NCT00243074 | S0509 - AZD2171 in Treating Patients With Malignant Pleural Mesothelioma That Cannot Be Removed By Surgery | completed | Phase 2 | 54 | National Cancer Institute (NCI)NIH | 1 | Jan 23, 2018 | clinicaltrials |
| NCT02497508 | Nivolumab in Patients With Recurrent Malignant Mesothelioma(NivoMes) | completed | Phase 2 | 33 | The Netherlands Cancer InstituteOTHER | 0 | Sep 14, 2017 | clinicaltrials |
| NCT01721018 | Intrapleural Administration of HSV1716 to Treat Patients With Malignant Pleural Mesothelioma.(1716-12) | completed | Phase 1 / Phase 2 | 12 | Virttu Biologics LimitedINDUSTRY | 1 | Jun 9, 2017 | clinicaltrials |
| NCT01204203 | Pilot Study of Bisphosphonate Therapy (Zoledronic Acid) in Patients With Malignant Mesothelioma (UAB 0901)(UAB0901) | completed | Phase 2 | 8 | University of Alabama at BirminghamOTHER | 1 | May 24, 2017 | clinicaltrials |
| NCT01211275 | Standard Chemotherapy With of Without Axitinib in Malignant Mesothelioma(N08CPA) | completed | Phase 1 / Phase 2 | 32 | The Netherlands Cancer InstituteOTHER | 1 | Feb 28, 2017 | clinicaltrials |
| NCT00017186 | Gemcitabine and Epirubicin in Treating Patients With Malignant Mesothelioma | completed | Phase 2 | 69 | Alliance for Clinical Trials in OncologyOTHER | 1 | Dec 7, 2016 | clinicaltrials |
| NCT00509041 | Dasatinib in Treating Patients With Previously Treated Malignant Mesothelioma | completed | Phase 2 | 46 | Alliance for Clinical Trials in OncologyOTHER | 1 | Aug 11, 2016 | clinicaltrials |
| NCT00004183 | Capecitabine in Treating Patients With Malignant Mesothelioma | completed | Phase 2 | 27 | Alliance for Clinical Trials in OncologyOTHER | 1 | Jul 14, 2016 | clinicaltrials |
| NCT00053885 | PTK787/ZK 222584 in Treating Patients With Unresectable Malignant Mesothelioma | completed | Phase 2 | 47 | Alliance for Clinical Trials in OncologyOTHER | 1 | Jul 1, 2016 | clinicaltrials |
| NCT00469196 | Tomotherapy Treatment for Mesothelioma | completed | Phase 2 | 18 | AHS Cancer Control AlbertaOTHER | 1 | Apr 6, 2016 | clinicaltrials |
| NCT00004547 | Treatment of Peritoneal Cancer With Surgery, Perfused Heated Cisplatin and Chemotherapy | completed | Phase 2 | 188 | National Cancer Institute (NCI)NIH | 1 | Nov 18, 2015 | clinicaltrials |
| NCT01024946 | Everolimus (RAD001) for the Treatment of Malignant Pleural Mesothelioma With Merlin/NF2 Loss as a Biomarker to Predict Sensitivity | completed | Phase 2 | 11 | Memorial Sloan Kettering Cancer CenterOTHER | 1 | May 12, 2015 | clinicaltrials |
| NCT00459862 | Pazopanib in Treating Patients With Malignant Pleural Mesothelioma | completed | Phase 2 | 34 | National Cancer Institute (NCI)NIH | 1 | Feb 24, 2015 | clinicaltrials |
| NCT00634205 | Phase II Study of Valproate and Doxorubicin in Malignant Mesothelioma | completed | Phase 2 | 45 | European Lung Cancer Working PartyOTHER | 2 | Feb 12, 2015 | clinicaltrials |
| NCT00513877 | Bortezomib in Treating Patients With Malignant Pleural Mesothelioma | completed | Phase 2 | 33 | Cancer Trials IrelandNETWORK | 4 | Dec 31, 2014 | clinicaltrials |
| NCT00309946 | Cediranib Maleate in Treating Patients With Malignant Mesothelioma That Cannot Be Removed By Surgery | completed | Phase 2 | 51 | National Cancer Institute (NCI)NIH | 1 | Jul 31, 2014 | clinicaltrials |
| NCT00392444 | Sunitinib in Treating Patients With Advanced Malignant Pleural Mesothelioma | completed | Phase 2 | 39 | National Cancer Institute (NCI)NIH | 1 | May 21, 2014 | clinicaltrials |
| NCT00165516 | Extrapleural Pneumonectomy With Intraoperative Intrathoracic/Intraperitoneal Heated Cisplatin With Amifostine and Sodium Thiosulfate | completed | Phase 2 | 85 | Dana-Farber Cancer InstituteOTHER | 1 | Mar 27, 2014 | clinicaltrials |
| NCT00027703 | Combination Chemotherapy With or Without Bevacizumab in Treating Patients With Malignant Mesothelioma | completed | Phase 2 | 106 | National Cancer Institute (NCI)NIH | 1 | Feb 11, 2014 | clinicaltrials |
| NCT00002475 | Cyclophosphamide Plus Vaccine Therapy in Treating Patients With Advanced Cancer | completed | Phase 2 | 40 | St. Vincent Medical Center - Los AngelesOTHER | 1 | Jul 10, 2013 | clinicaltrials |
| NCT00002608 | Combination Chemotherapy and Tamoxifen in Treating Patients With Solid Tumors | completed | Phase 2 | 30 | Ottawa Regional Cancer CentreOTHER | 1 | Jul 10, 2013 | clinicaltrials |
| NCT00062283 | Alanosine in Treating Patients With Cancer | completed | Phase 2 | — | Memorial Sloan Kettering Cancer CenterOTHER | 1 | Jun 26, 2013 | clinicaltrials |
| NCT00107432 | Sorafenib Tosylate in Treating Patients With Malignant Mesothelioma. | completed | Phase 2 | 44 | National Cancer Institute (NCI)NIH | 1 | Jun 5, 2013 | clinicaltrials |
| NCT00006014 | SU5416 in Treating Patients With Malignant Mesothelioma | completed | Phase 2 | 45 | National Cancer Institute (NCI)NIH | 1 | Jun 3, 2013 | clinicaltrials |
| NCT00039182 | Erlotinib in Treating Patients With Malignant Mesothelioma of the Lung | completed | Phase 2 | 55 | National Cancer Institute (NCI)NIH | 1 | Jan 24, 2013 | clinicaltrials |
| NCT00025207 | Gefitinib in Treating Patients With Malignant Mesothelioma | completed | Phase 2 | 40 | National Cancer Institute (NCI)NIH | 1 | Jan 17, 2013 | clinicaltrials |
| NCT00003723 | S9810: Gemcitabine Plus Cisplatin in Treating Patients With Malignant Mesothelioma of the Pleura That Cannot Be Removed by Surgery | completed | Phase 2 | 57 | SWOG Cancer Research NetworkNETWORK | 1 | Oct 8, 2012 | clinicaltrials |
| NCT00004254 | Raltitrexed in Treating Patients With Malignant Mesothelioma That Cannot Be Surgically Removed | completed | Phase 2 | 25 | European Organisation for Research and Treatment of Cancer - EORTCNETWORK | 2 | Jul 18, 2012 | clinicaltrials |
| NCT00227630 | Pemetrexed Disodium and Cisplatin Followed By Surgery and Radiation Therapy in Treating Patients With Malignant Pleural Mesothelioma | completed | Phase 2 | 59 | European Organisation for Research and Treatment of Cancer - EORTCNETWORK | 4 | Jul 18, 2012 | clinicaltrials |
| NCT00787410 | An Open-label, Phase II Trial of ZD1839 (IRESSA) in Patients With Malignant Mesothelioma | completed | Phase 2 | 23 | AstraZenecaINDUSTRY | 0 | Jun 6, 2012 | clinicaltrials |
| NCT00030745 | Combination Chemotherapy Before Surgery in Treating Patients With Mesothelioma of the Lung | completed | Phase 2 | 61 | Swiss Cancer InstituteOTHER | 1 | May 15, 2012 | clinicaltrials |
Data updated 22 days agoSource updated Jan 20, 2021source: clinicaltrials