Subtype
Malignant Large Intestinal Neoplasm
CI-CAN-00003173Explore in graph →
1,622 active trials21 approved drugs383 evidence items
- NCIt
- C215202
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Subtype
CI-CAN-00003173Explore in graph →
Clinical trials
7,502 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
Computedformula ci-trial-intel-v1 · interventional studies · entity + NCIt descendants · hover a figure for its formulaCompare cancersTerminated studies (742)
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT02273167 | Multicenter Randomized Parallel Group Phase III Study Comparing the Bowel Cleansing Efficacy, Safety and Tolerability of NER1006 Versus MOVIPREP® Using 2-Day Split-Dosing and 1-Day Morning Split-Dosing Regimen in Adults.(MORA) | completed | Phase 3 | 849 | NorgineINDUSTRY | 7 | May 15, 2018 | clinicaltrials |
| NCT02706184 | E. Coli Nissle in Oncology(EcNO) | completed | Phase 3 | 20 | University of HohenheimOTHER | 1 | May 15, 2018 |
| clinicaltrials |
| NCT02284139 | Pilot Trial of EGF Ointment for the Patients With EGFR-i Related Skin Side Effects | completed | Phase 2 / Phase 3 | 90 | Dong-A University HospitalOTHER | 1 | Apr 23, 2018 | clinicaltrials |
| NCT00758186 | Randomized Trial of Colonic Stents as a Bridge to Surgery | completed | Phase 3 | 40 | Singapore General HospitalOTHER | 1 | Apr 18, 2018 | clinicaltrials |
| NCT02907385 | Efficacy and Safety of LifeSeal™ Kit for Colorectal Staple Line Sealing | unknown | Phase 3 | 736 | LifeBond Ltd.INDUSTRY | 7 | Mar 30, 2018 | clinicaltrials |
| NCT01918852 | S-1 Versus Capecitabine in the First Line Treatment of MCC Patients.(SALTO) | completed | Phase 3 | 161 | Dutch Colorectal Cancer GroupOTHER | 1 | Mar 14, 2018 | clinicaltrials |
| NCT01196260 | Combination Chemotherapy Treatments in Patients With Colorectal Cancer Stage II and III | unknown | Phase 2 / Phase 3 | 8,000 | State Key Laboratory of Cancer BiologyNETWORK | 1 | Feb 20, 2018 | clinicaltrials |
| NCT03431428 | Comparison of Short-term Efficacy and Long-term Prognosis for Reduction Surgery and Radical Resection in Almost-cCR Rectal Cancer Patients | unknown | Phase 3 | 477 | Zhang RuiOTHER | 1 | Feb 13, 2018 | clinicaltrials |
| NCT02163187 | Sacral Neuromodulation (SNM) With InterStimTM for Bowel Dysfunction Following Surgery for Rectal Cancers With Sphincter Preservation | terminated | Phase 2 / Phase 3 | 4 | Memorial Sloan Kettering Cancer CenterOTHER | 1 | Feb 5, 2018 | clinicaltrials |
| NCT00911170 | PAVES: Pegfilgrastim Anti-vascular Endothelial Growth Factor (VEGF) Evaluation Study | completed | Phase 3 | 847 | AmgenINDUSTRY | 17 | Dec 29, 2017 | clinicaltrials |
| NCT01279681 | Combination Chemotherapy Plus Bevacizumab With or Without Oxaliplatin in Treating Older Patients With Metastatic Colorectal Cancer | terminated | Phase 3 | 32 | Alliance for Clinical Trials in OncologyOTHER | 0 | Dec 8, 2017 | clinicaltrials |
| NCT03362684 | PETACC-8 miR-31-3p and miR-31-5p Ancillary Study | completed | Phase 3 | 1,808 | IntegraGen SAINDUSTRY | 0 | Dec 5, 2017 | clinicaltrials |
| NCT01694966 | The Safety and Efficacy of Methylene Blue MMX® Modified Release Tablets Administered to Subjects Undergoing Screening or Surveillance Colonoscopy | completed | Phase 3 | 1,249 | Cosmo Technologies LtdINDUSTRY | 8 | Nov 6, 2017 | clinicaltrials |
| NCT02369939 | Effects of Deep Regional Hyperthermia in Patients With Anal Carcinoma Treated by Standard Radiochemotherapy(HYCAN) | unknown | Phase 3 | 118 | University of Erlangen-Nürnberg Medical SchoolOTHER | 1 | Aug 11, 2017 | clinicaltrials |
| NCT01308086 | Adjuvant Therapy(3 vs. 6 Months) With the FOLFOX 4 or XELOX for Stage II or Stage III Colon Cancer | unknown | Phase 3 | 2,000 | Hellenic Oncology Research GroupOTHER | 1 | Aug 9, 2017 | clinicaltrials |
| NCT03242187 | Trans-anal Versus Laparoscopic TME for Mid and Low Rectal Cancer(MansTaTME) | unknown | Phase 2 / Phase 3 | 30 | Mansoura UniversityOTHER | 1 | Aug 8, 2017 | clinicaltrials |
| NCT01309126 | Study of Imprime PGG® in Combination With Cetuximab in Subjects With Recurrent or Progressive KRAS Wild Type Colorectal Cancer(PRIMUS) | terminated | Phase 3 | 217 | HiberCell, Inc.INDUSTRY | 4 | Jul 13, 2017 | clinicaltrials |
| NCT01895257 | Comparing HAI-90Y (SIR-spheres)+Chemotx LV5FU2 Versus Chemotx LV5FU2 Alone to Treat Colorectal Cancer | unknown | Phase 3 | 162 | Universiteit AntwerpenOTHER | 1 | Jul 7, 2017 | clinicaltrials |
| NCT00883792 | The Northern-European Initiative on Colorectal Cancer(NordICC) | active not recruiting | Phase 3 | 95,000 | Oslo University HospitalOTHER | 6 | Jun 19, 2017 | clinicaltrials |
| NCT00687830 | Efficacy of Morning-only Bowel Preparation for Afternoon Colonoscopy.(CCF) | completed | Phase 3 | 136 | Cleveland Clinic FloridaOTHER | 1 | May 17, 2017 | clinicaltrials |
| NCT01646554 | Efficacy of FOLFOX Versus FOLFOX Plus Aflibercept in K-ras Mutant Patients With Resectable Liver Metastases(BOS3) | withdrawn | Phase 2 / Phase 3 | 0 | European Organisation for Research and Treatment of Cancer - EORTCNETWORK | 0 | May 9, 2017 | clinicaltrials |
| NCT02060669 | Xeloda Maintenance Versus BSC in Metastatic Colorectal Cancer | terminated | Phase 3 | 10 | Samsung Medical CenterOTHER | 1 | Apr 27, 2017 | clinicaltrials |
| NCT03125980 | Perioperative Versus Postoperative CapOX Chemotherapy for Locally Advanced Colon Cancer | recruiting | Phase 3 | 1,370 | Fudan UniversityOTHER | 1 | Apr 24, 2017 | clinicaltrials |
| NCT00509444 | Cancer Prevention and Treatment Among African American Older Adults: Treatment Trial(CPTD) | completed | Phase 3 | 200 | Johns Hopkins Bloomberg School of Public HealthOTHER | 1 | Apr 20, 2017 | clinicaltrials |
| NCT00384176 | First Line Metastatic Colorectal Cancer Therapy in Combination With FOLFOX(HORIZON III) | completed | Phase 2 / Phase 3 | 1,814 | AstraZenecaINDUSTRY | 28 | Apr 14, 2017 | clinicaltrials |
| NCT01523431 | Individual Dosage Selection of Irinotecan (CPT-11) Based on UGT1A1 Genotype in Metastatic Colorectal Cancer Patients | completed | Phase 2 / Phase 3 | 583 | The Affiliated Hospital of the Chinese Academy of Military Medical SciencesOTHER | 1 | Mar 30, 2017 | clinicaltrials |
| NCT00153816 | Vitamin D/Calcium Polyp Prevention Study | completed | Phase 2 / Phase 3 | 2,813 | Dartmouth-Hitchcock Medical CenterOTHER | 2 | Mar 15, 2017 | clinicaltrials |
| NCT01412957 | Comparison of Survival Benefit of Panitumumab With Supportive Care to Best Supportive Care Alone in Patients With Metastatic Colorectal Cancer | completed | Phase 3 | 377 | AmgenINDUSTRY | 16 | Mar 15, 2017 | clinicaltrials |
| NCT03038217 | Investigation of the Value of ctDNA in Diagnosis, Treatment, and Surveillance of Surgically Resectable Colorectal Cancer | unknown | Phase 3 | 300 | Peking Union Medical College HospitalOTHER | 0 | Feb 3, 2017 | clinicaltrials |
| NCT01786694 | Feasibility of Microdialysis by Laparoscopy(MTM-COLON-I) | completed | Phase 3 | 11 | Centre Hospitalier Universitaire, AmiensOTHER | 1 | Feb 1, 2017 | clinicaltrials |
| NCT00003596 | Chemotherapy Plus Radiation Therapy in Treating Patients With Stage II or Stage III Anal Cancer | completed | Phase 3 | 682 | Radiation Therapy Oncology GroupNETWORK | 2 | Jan 4, 2017 | clinicaltrials |
| NCT00399035 | Cediranib (AZD2171, RECENTIN™) in Addition to Chemotherapy in Patients With Untreated Metastatic Colorectal Cancer(HORIZON II) | completed | Phase 3 | 1,254 | AstraZenecaINDUSTRY | 15 | Dec 28, 2016 | clinicaltrials |
| NCT01169558 | A Study of Bevacizumab (Avastin) in Combination With Chemotherapy in Participants With Metastatic Cancer of the Colon or Rectum. | completed | Phase 3 | 168 | Hoffmann-La RocheINDUSTRY | 1 | Dec 8, 2016 | clinicaltrials |
| NCT02978313 | Cetuximab Monotherapy Maintenance Treatment in mCRC | unknown | Phase 2 / Phase 3 | 500 | Ruijin HospitalOTHER | 0 | Nov 30, 2016 | clinicaltrials |
| NCT01338558 | A Study of Avastin (Bevacizumab) in Combination With mFOLFOX6 in Treatment-Naïve Patients With Metastatic Colorectal Cancer With or Without K-RAS Mutations, and Comparison to Cetuximab | withdrawn | Phase 3 | 0 | Hoffmann-La RocheINDUSTRY | 0 | Nov 2, 2016 | clinicaltrials |
| NCT02935764 | FOLFIRI Versus Irinotecan as Second-line Treatment in Metastatic Colorectal Cancer Patients | unknown | Phase 3 | 164 | Fudan UniversityOTHER | 0 | Oct 17, 2016 | clinicaltrials |
| NCT00766155 | Chemotherapy and Radiation Therapy Before Surgery Followed by Capecitabine With or Without Oxaliplatin in Treating Patients With Locally Advanced Rectal Cancer(PETACC-6) | completed | Phase 3 | 1,094 | European Organisation for Research and Treatment of Cancer - EORTCNETWORK | 0 | Oct 12, 2016 | clinicaltrials |
| NCT02266849 | Loperamide vs. Placebo's Effect on Ileostomy Output: A Clinical Randomized Blinded Cross-over Study | terminated | Phase 3 | 12 | Odense University HospitalOTHER | 1 | Oct 11, 2016 | clinicaltrials |
| NCT01372007 | Influence of Somatuline Autogel 120mg on Post-operative Drainage After Total Mesorectum Excision for Rectumcarcinoma | completed | Phase 3 | 24 | University Hospital, GhentOTHER | 1 | Oct 7, 2016 | clinicaltrials |
| NCT00069095 | A Study of Capecitabine (Xeloda) and Bevacizumab as a First-line Therapy in Patients With Metastatic Colorectal Cancer | completed | Phase 3 | 2,035 | Hoffmann-La RocheINDUSTRY | 33 | Oct 6, 2016 | clinicaltrials |
| NCT00392899 | Tegafur-Uracil or Observation in Treating Patients With Stage II Colorectal Cancer That Has Been Completely Removed By Surgery | completed | Phase 3 | 2,025 | Translational Research Center for Medical Innovation, Kobe, Hyogo, JapanOTHER | 1 | Sep 28, 2016 | clinicaltrials |
| NCT02912052 | Perioperative Chemotherapy VS Postoperative Chemotherapy for the Treatment of Colon Cancer With Resectable Liver Metastasis(PEPCORLI) | unknown | Phase 3 | 240 | The First Affiliated Hospital with Nanjing Medical UniversityOTHER | 1 | Sep 23, 2016 | clinicaltrials |
| NCT00147134 | A Trial to Evaluate Laparoscopic Versus Open Surgery for Colorectal Cancer | completed | Phase 3 | 1,050 | Haruhiko FukudaOTHER | 1 | Sep 22, 2016 | clinicaltrials |
| NCT02905968 | Transanual Tube Placement in Low Anterior Resection (LAR) for Rectal Cancer | unknown | Phase 2 / Phase 3 | 520 | Fudan UniversityOTHER | 1 | Sep 19, 2016 | clinicaltrials |
| NCT02893540 | Metronomic Versus Conventional Chemotherapy in as Maintenance Treatment in mCRC | unknown | Phase 2 / Phase 3 | 250 | Ruijin HospitalOTHER | 1 | Sep 16, 2016 | clinicaltrials |
| NCT00002523 | Radiation Therapy, Surgery, and Chemotherapy in Treating Patients With Rectal Cancer That Can Be Surgically Removed | completed | Phase 3 | 1,011 | European Organisation for Research and Treatment of Cancer - EORTCNETWORK | 10 | Sep 2, 2016 | clinicaltrials |
| NCT02635503 | Safety Study of Totally Laparoscopic Resection With Natural Orifice Specimen Extraction (NOSE) for Rectosigmoid Cancer | unknown | Phase 3 | 366 | Cancer Institute and Hospital, Chinese Academy of Medical SciencesOTHER | 1 | Sep 2, 2016 | clinicaltrials |
| NCT02882269 | Neoadjuvant Chemotherapy for the Treatment of Resectable Locally Advanced Colon Cancer | unknown | Phase 2 / Phase 3 | 400 | The First Affiliated Hospital with Nanjing Medical UniversityOTHER | 0 | Aug 30, 2016 | clinicaltrials |
| NCT00316914 | Calcium Gluconate and Magnesium Sulfate in Preventing Neurotoxicity Caused By Oxaliplatin in Patients Receiving Combination Chemotherapy for Stage II, Stage III, or Stage IV Colorectal Cancer That Has Been Completely Removed By Surgery | completed | Phase 3 | 104 | Alliance for Clinical Trials in OncologyOTHER | 1 | Aug 11, 2016 | clinicaltrials |
Data updated 23 days agoSource updated May 15, 2018source: clinicaltrials