Subtype
Malignant Large Intestinal Neoplasm
CI-CAN-00003173Explore in graph →
1,622 active trials21 approved drugs383 evidence items
- NCIt
- C215202
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Subtype
CI-CAN-00003173Explore in graph →
Clinical trials
7,502 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
Computedformula ci-trial-intel-v1 · interventional studies · entity + NCIt descendants · hover a figure for its formulaCompare cancersTerminated studies (742)
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT04303429 | Adjuvant Chemotherapy in High Risk Stage II Colon Cancer | unknown | Phase 3 | 962 | Shanghai General Hospital, Shanghai Jiao Tong University School of MedicineOTHER | 0 | Apr 8, 2020 | clinicaltrials |
| NCT00002570 | Immediate Compared With Delayed Chemotherapy in Advanced Colorectal Cancer Without Signs or Symptoms of Disease | completed | Phase 3 | 67 | NCIC Clinical Trials GroupNETWORK | 1 | Apr 6, 2020 |
| NCT00952029 | Combination Chemotherapy and Bevacizumab With or Without Bevacizumab Maintenance Therapy in Treating Patients With Metastatic Colorectal Cancer | completed | Phase 2 / Phase 3 | 492 | Federation Francophone de Cancerologie DigestiveOTHER | 1 | Mar 30, 2020 | clinicaltrials |
| NCT00207831 | Trial Testing Ftorafur (UFT) Associated With Neoadjuvant Radiotherapy Versus Radiotherapy Alone in Rectal Adenocarcinoma(UFT RT Phase 3) | terminated | Phase 3 | 219 | Institut Cancerologie de l'OuestOTHER | 1 | Mar 25, 2020 | clinicaltrials |
| NCT00272324 | Aspirin/Folate Prevention of Large Bowel Polyps | completed | Phase 2 / Phase 3 | 1,121 | Dartmouth-Hitchcock Medical CenterOTHER | 2 | Mar 13, 2020 | clinicaltrials |
| NCT00069121 | A Study of Xeloda (Capecitabine) Plus Oxaliplatin in Patients With Colon Cancer | completed | Phase 3 | 1,886 | Hoffmann-La RocheINDUSTRY | 29 | Mar 6, 2020 | clinicaltrials |
| NCT03448549 | SOX Versus XELOX as Adjuvant Chemotherapy for Stage III Colorectal Cancer Patients | unknown | Phase 3 | 1,191 | Peking University Cancer Hospital & InstituteOTHER | 1 | Mar 6, 2020 | clinicaltrials |
| NCT00544700 | Bevacizumab in Treating Patients Who Have Undergone First-Line Therapy for Metastatic Colorectal Cancer | terminated | Phase 3 | 265 | Swiss Cancer InstituteOTHER | 1 | Feb 20, 2020 | clinicaltrials |
| NCT02314819 | A Phase III Trial Evaluating Fruquintinib Efficacy and Safety in 3+ Line Colorectal Cancer Patients （FRESCO)(FRESCO) | completed | Phase 3 | 416 | Hutchison Medipharma LimitedINDUSTRY | 1 | Feb 17, 2020 | clinicaltrials |
| NCT02339116 | Folfoxiri Plus Bev Followed by Reintroduction of Folfoxiri Plus Bev at Progression Versus Folfox Plus Bev Followed by Folfiri Plus Bev in mCRC(TRIBE2) | unknown | Phase 3 | 654 | Gruppo Oncologico del Nord-OvestOTHER | 1 | Feb 5, 2020 | clinicaltrials |
| NCT01228734 | A Trial to Compare Oxaliplatin, Folinic Acid (FA) and 5-Fluorouracil (5FU) Combination Chemotherapy (FOLFOX-4) With or Without Cetuximab in the 1st Line Treatment of Metastatic Colorectal Cancer (mCRC) in Chinese Rat Sarcoma Viral Oncogene Homolog (RAS) Wild-type Patients(TAILOR) | completed | Phase 3 | 553 | Merck KGaA, Darmstadt, GermanyINDUSTRY | 1 | Jan 28, 2020 | clinicaltrials |
| NCT02928692 | Minocycline Attenuate Postoperative Cognitive Dysfunction and Delirium(MAPOCD) | unknown | Phase 3 | 750 | RenJi HospitalOTHER | 1 | Jan 28, 2020 | clinicaltrials |
| NCT01741038 | AlloStim® In-Situ Vaccine in Pre-Treated Metastatic Colorectal Cancer | withdrawn | Phase 2 / Phase 3 | 0 | Mirror Biologics, Inc.INDUSTRY | 1 | Jan 22, 2020 | clinicaltrials |
| NCT00706121 | S0000D: Effect of Vitamin E and/or Selenium on Colorectal Polyps in Men Enrolled on SELECT Trial SWOG-S0000(ACP) | completed | Phase 3 | 8,094 | SWOG Cancer Research NetworkNETWORK | 1 | Dec 16, 2019 | clinicaltrials |
| NCT01902823 | Effect of Cancer Nurse Navigators on Patient Outcomes | terminated | Phase 2 / Phase 3 | 16 | University of Wisconsin, MadisonOTHER | 1 | Dec 13, 2019 | clinicaltrials |
| NCT02788279 | A Study to Investigate Efficacy and Safety of Cobimetinib Plus Atezolizumab and Atezolizumab Monotherapy Versus Regorafenib in Participants With Metastatic Colorectal Adenocarcinoma (COTEZO IMblaze370) | completed | Phase 3 | 363 | Hoffmann-La RocheINDUSTRY | 11 | Dec 11, 2019 | clinicaltrials |
| NCT02251977 | Effect of GM1 in Prevention of Oxaliplatin Induced Neurotoxicity in Stage II/III Colorectal Cancer | completed | Phase 3 | 196 | Yuhong LiOTHER | 1 | Oct 7, 2019 | clinicaltrials |
| NCT01183780 | A Study in Second Line Metastatic Colorectal Cancer | completed | Phase 3 | 1,072 | Eli Lilly and CompanyINDUSTRY | 26 | Sep 25, 2019 | clinicaltrials |
| NCT00078897 | Selenium for Prevention of Adenomatous Colorectal Polyps | terminated | Phase 3 | 1,621 | University of ArizonaOTHER | 1 | Sep 24, 2019 | clinicaltrials |
| NCT02077868 | Evaluation of MGN1703 Maintenance Treatment in Patients With mCRC With Tumor Reduction During Induction Treatment(IMPALA) | unknown | Phase 3 | 540 | Mologen AGINDUSTRY | 8 | Sep 10, 2019 | clinicaltrials |
| NCT00096278 | Fluorouracil, Leucovorin, and Oxaliplatin With or Without Bevacizumab in Treating Patients Who Have Undergone Surgery for Stage II or Stage III Colon Cancer | completed | Phase 3 | 2,710 | National Cancer Institute (NCI)NIH | 1 | Jul 30, 2019 | clinicaltrials |
| NCT03522649 | A Phase III Clinical Study of Napabucasin (GB201) Plus FOLFIRI in Adult Patients With Metastatic Colorectal Cancer | unknown | Phase 3 | 668 | 1Globe Health Institute LLCINDUSTRY | 1 | Jun 18, 2019 | clinicaltrials |
| NCT02736942 | COLOR III Trial: Transanal vs Laparoscopic TME(COLORIII) | unknown | Phase 3 | 1,104 | Amsterdam UMC, location VUmcOTHER | 1 | Jun 6, 2019 | clinicaltrials |
| NCT03975049 | Triplet Combination or Doublet Regimen Versus Chemoradiation as Neoadjuvant Therapy for Locally Advanced Rectal Cancer | not yet recruiting | Phase 3 | 933 | Sixth Affiliated Hospital, Sun Yat-sen UniversityOTHER | 0 | Jun 5, 2019 | clinicaltrials |
| NCT01092481 | Study Investigating the Role of Oxaliplatin Duration in Modified FOLFOX-6 or CAPOX Regimen as Adjuvant Colon Cancer Therapy | unknown | Phase 3 | 1,580 | Samsung Medical CenterOTHER | 1 | May 21, 2019 | clinicaltrials |
| NCT02332499 | Study of Anlotinib in Patients With Metastatic Colorectal Cancer（mCRC）(ALTER0703)(ALTER0703) | completed | Phase 2 / Phase 3 | 419 | Chia Tai Tianqing Pharmaceutical Group Co., Ltd.INDUSTRY | 1 | May 21, 2019 | clinicaltrials |
| NCT00647530 | Fluorouracil and Oxaliplatin With or Without Panitumumab In Treating Patients With High-Risk Colon Cancer That Can Be Removed by Surgery(FOxTROT) | unknown | Phase 2 / Phase 3 | 1,053 | University of BirminghamOTHER | 1 | May 17, 2019 | clinicaltrials |
| NCT00238381 | Rectal Reconstruction in Treating Patients Who Are Undergoing Surgery for Rectal Cancer | completed | Phase 3 | 336 | Swiss Cancer InstituteOTHER | 2 | May 15, 2019 | clinicaltrials |
| NCT03925662 | Mebendazole as Adjuvant Treatment for Colon Cancer | recruiting | Phase 3 | 40 | Sherief Abd-ElsalamOTHER | 1 | Apr 24, 2019 | clinicaltrials |
| NCT01640405 | Study of 5-Fluorouracil/Leucovorin/Oxaliplatin (FOLFOX) + Bevacizumab Versus 5-Fluorouracil/Leucovorin/Oxaliplatin/Irinotecan (FOLFOXIRI) + Bevacizumab as First Line Treatment of Patients With Metastatic Colorectal Cancer Not Previously Treated and With Three or More Circulating Tumoral Cells(VISNU-1) | completed | Phase 3 | 350 | Spanish Cooperative Group for the Treatment of Digestive Tumours (TTD)OTHER | 1 | Apr 11, 2019 | clinicaltrials |
| NCT01550055 | Study of CMAB009 to Treat KRAS Wild Type Metastatic Colorectal Cancer(CRC009) | completed | Phase 2 / Phase 3 | 512 | Shanghai Zhangjiang Biotechnology Limited CompanyINDUSTRY | 0 | Apr 10, 2019 | clinicaltrials |
| NCT00252564 | Cetuximab, Bevacizumab & 5FU/Leucovorin vs. Oxaliplatin, Bevacizumab & 5FU/Leucovorin in Metastatic Colorectal Cancer | completed | Phase 3 | 247 | US Oncology ResearchINDUSTRY | 1 | Feb 15, 2019 | clinicaltrials |
| NCT02605044 | Masitinib in Combination With FOLFIRI for Second-line Treatment of Patients With Metastatic Colorectal Cancer | terminated | Phase 3 | 123 | AB ScienceINDUSTRY | 3 | Feb 11, 2019 | clinicaltrials |
| NCT03717038 | Sym004 Versus TAS-102 in Patients With mCRC | withdrawn | Phase 3 | 0 | Symphogen A/SINDUSTRY | 0 | Feb 4, 2019 | clinicaltrials |
| NCT03671252 | Prospectively Randomized Control Clinical Trial of FOLFOXIRI Preoperative Chemotherapy Alone on Rectal Cancer in Local Advance Comparing to Oral Capecitabine Combined With Long-term Radiation | recruiting | Phase 3 | 776 | Sun Yat-sen UniversityOTHER | 1 | Jan 23, 2019 | clinicaltrials |
| NCT00068692 | Comparison of Adjuvant Chemotherapy Regimens in Treating Stage II/III Rectal Cancer | completed | Phase 3 | 225 | National Cancer Institute (NCI)NIH | 1 | Dec 4, 2018 | clinicaltrials |
| NCT01651949 | Multivalent HPV (Human Papillomavirus) Vaccine Study in 16- to 26-Year Old Men and Women (V503-003) | completed | Phase 3 | 2,520 | Merck Sharp & Dohme LLCINDUSTRY | 0 | Nov 27, 2018 | clinicaltrials |
| NCT00254436 | A Double-Blind, Randomized, Placebo-Controlled Study of the Efficacy and Safety of Weekly Procrit Given to Gastric or Rectal Patients | terminated | Phase 3 | 50 | M.D. Anderson Cancer CenterOTHER | 1 | Oct 25, 2018 | clinicaltrials |
| NCT03716063 | Strengthening the Spleen and Reducing Phlegm Method in Improving Radical Resection Rate of Colorectal Cancer | unknown | Phase 3 | 350 | Xiyuan Hospital of China Academy of Chinese Medical SciencesOTHER | 1 | Oct 23, 2018 | clinicaltrials |
| NCT00115765 | PACCE: Panitumumab Advanced Colorectal Cancer Evaluation Study | completed | Phase 3 | 1,053 | AmgenINDUSTRY | 0 | Oct 17, 2018 | clinicaltrials |
| NCT00032344 | Long-term Follow-up Study Designed to Evaluate the Relative Risk of Two Colonoscopy Schedules for Patients With Small Polyps | completed | Phase 3 | 3,200 | US Department of Veterans AffairsFED | 1 | Aug 31, 2018 | clinicaltrials |
| NCT02526836 | Complete Mesocolic Excision With Central Vessel Ligation Compared With Conventional Surgery for Colon Cancer | unknown | Phase 2 / Phase 3 | 40 | Mansoura UniversityOTHER | 2 | Aug 16, 2018 | clinicaltrials |
| NCT01842971 | ALPPS (Liver Partition and Portal Vein Ligation) for Two-stage Hepatectomy for Colorectal Liver Metastasis | terminated | Phase 3 | 3 | Centre Hospitalier Universitaire, AmiensOTHER | 1 | Aug 2, 2018 | clinicaltrials |
| NCT03606863 | Peripheral Parenteral Nutrition vs Conventional Fluid in Colorectal Resection in ERAS | unknown | Phase 3 | 200 | Antonio Arroyo SebastianOTHER | 1 | Jul 31, 2018 | clinicaltrials |
| NCT00749450 | Combination Chemotherapy After Surgery in Treating Patients With High-Risk Stage II or Stage III Colorectal Cancer | completed | Phase 3 | 6,088 | Cancer Research UK, GlasgowOTHER | 1 | Jul 27, 2018 | clinicaltrials |
| NCT02127645 | Neoadjuvant Radiotherapy Followed by Transanal Endoscopic Microsurgery for T1-T2 Extraperitoneal Rectal Cancer(NERATEM) | completed | Phase 3 | 25 | European Association for Endoscopic SurgeryOTHER | 1 | Jul 26, 2018 | clinicaltrials |
| NCT02965248 | Adjuvant Hyperthermic Intraperitoneal Chemotherapy (HIPEC) Versus no HIPEC in Locally Advanced Colorectal Cancer (APEC Study) | unknown | Phase 3 | 147 | Fudan UniversityOTHER | 1 | Jun 19, 2018 | clinicaltrials |
| NCT00077233 | FOLFIRI or FOLFOX With or Without Cetuximab in Patients With Metastatic Adenocarcinoma of the Colon or Rectum | terminated | Phase 3 | 238 | Alliance for Clinical Trials in OncologyOTHER | 1 | May 16, 2018 | clinicaltrials |
Data updated 23 days agoSource updated Apr 8, 2020source: clinicaltrials