Subtype
Malignant Large Intestinal Neoplasm
CI-CAN-00003173Explore in graph →
1,622 active trials21 approved drugs383 evidence items
- NCIt
- C215202
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Subtype
CI-CAN-00003173Explore in graph →
Clinical trials
7,502 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
Computedformula ci-trial-intel-v1 · interventional studies · entity + NCIt descendants · hover a figure for its formulaCompare cancersTerminated studies (742)
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT05194878 | Neoadjuvant FOLFOXIRI Versus Immediate Surgery for Stage II and III Colon Cancers | recruiting | Phase 3 | 840 | Sun Yat-sen UniversityOTHER | 1 | Jan 18, 2022 | clinicaltrials |
| NCT03654729 | Preventive Treatment of Oxaliplatin Induced Peripheral Neuropathy in Metastatic Colorectal Cancer (POLAR-M)(POLAR-M) | terminated | Phase 3 | 291 | Egetis TherapeuticsINDUSTRY | 13 | Dec 17, 2021 | clinicaltrials |
| NCT00995202 | Follow-Up Care With or Without CEA Assessments in Patients Who Have Undergone Surgery for Stage II or Stage III Colorectal Cancer(SURVEILLANCE) | completed | Phase 3 | 1,997 | Federation Francophone de Cancerologie DigestiveOTHER | 3 | Dec 7, 2021 | clinicaltrials |
| NCT01308190 | Preoperative Chemoradiotherapy and Transanal Endoscopic Microsurgery Versus Total Mesorectal Excision in T2-T3s N0, M0 Rectal Cancer | completed | Phase 3 | 173 | Corporacion Parc TauliOTHER | 1 | Nov 23, 2021 | clinicaltrials |
| NCT05086614 | Thymosin-alpha 1 for Adjuvant Treatment After Radical Resection of High-risk Stage II and III Colorectal Cancer | recruiting | Phase 3 | 2,500 | Fudan UniversityOTHER | 1 | Oct 21, 2021 | clinicaltrials |
| NCT05079438 | Dendrobium Huoshanense Suppository in Rectal Cancer | unknown | Phase 3 | 168 | Zhejiang Cancer HospitalOTHER | 1 | Oct 15, 2021 | clinicaltrials |
| NCT00070213 | Leucovorin and Fluorouracil With or Without Oxaliplatin Compared to Capecitabine With or Without Oxaliplatin in Treating Patients With Metastatic Colorectal Cancer | completed | Phase 3 | 460 | Medical Research CouncilOTHER_GOV | 1 | Sep 27, 2021 | clinicaltrials |
| NCT04781270 | mFOLFOXIRI+Bev vs. mFOLFOX6+Bev for RAS Mutant Unresectable Colorectal Liver-limited Metastases | unknown | Phase 3 | 308 | Fudan UniversityOTHER | 1 | Sep 27, 2021 | clinicaltrials |
| NCT01927497 | Biological Mesh Closure of the Pelvic Floor After Extralevator Abdomino Perineal Resection for Rectal Cancer(BIOPEX) | completed | Phase 3 | 104 | Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)OTHER | 1 | Aug 17, 2021 | clinicaltrials |
| NCT02909478 | Aprepitant Without Steroid in Preventing Chemotherapy-induced Nausea and Vomiting in Patients With Colorectal Cancer | completed | Phase 3 | 315 | Sun Yat-sen UniversityOTHER | 1 | Jul 29, 2021 | clinicaltrials |
| NCT02533271 | Optimization of Preoperative Treatment in Locally Advanced Rectal Cancer(STELLAR) | unknown | Phase 3 | 600 | Chinese Academy of Medical SciencesOTHER | 1 | Jul 16, 2021 | clinicaltrials |
| NCT01767857 | A Phase III Study of Xilonix in Patients With Advanced Colorectal Cancer(XCITE) | terminated | Phase 3 | 643 | Janssen Research & Development, LLCINDUSTRY | 13 | Jun 29, 2021 | clinicaltrials |
| NCT04917289 | CTC vs Radiography as the Evidence of Recurrence in Colorectal Cancer Patients | unknown | Phase 3 | 100 | Fudan UniversityOTHER | 0 | Jun 8, 2021 | clinicaltrials |
| NCT04912258 | Preoperative Irinotecan Drug-eluting Beads for Patients With Unresectable Colorectal Liver Metastasis | unknown | Phase 3 | 80 | Fudan UniversityOTHER | 1 | Jun 3, 2021 | clinicaltrials |
| NCT01455831 | Extended Peri-operative Tinzaparin to Improve Disease-free Survival in Patients With Resectable Colorectal Cancer(PERIOP-01) | completed | Phase 3 | 616 | Ottawa Hospital Research InstituteOTHER | 3 | May 17, 2021 | clinicaltrials |
| NCT03158610 | Biological-guided Metronomic Chemotherapy as Maintenance Strategy in Metastatic Colorectal Cancer | terminated | Phase 2 / Phase 3 | 20 | Ruijin HospitalOTHER | 1 | May 3, 2021 | clinicaltrials |
| NCT02942706 | Cetuximab Maintenance Treatment Versus Continuation After Induction Therapy in mCRC | unknown | Phase 2 / Phase 3 | 200 | Ruijin HospitalOTHER | 0 | Apr 30, 2021 | clinicaltrials |
| NCT02138422 | A Phase 3 Study to Evaluate Xilonix as an Anticancer Therapy in Patients With Symptomatic Colorectal Cancer | completed | Phase 3 | 276 | Janssen Research & Development, LLCINDUSTRY | 1 | Mar 1, 2021 | clinicaltrials |
| NCT00003652 | Combination Chemotherapy Plus Radiation Therapy in Treating Patients With Stage II or Stage III Anal Cancer | completed | Phase 3 | 350 | UNICANCEROTHER | 1 | Feb 17, 2021 | clinicaltrials |
| NCT00005979 | Combination Chemotherapy With or Without Irinotecan in Treating Patients With Stage III Colon Cancer | completed | Phase 3 | — | UNICANCEROTHER | 1 | Feb 17, 2021 | clinicaltrials |
| NCT00227747 | Radiation Therapy and Capecitabine With or Without Oxaliplatin in Treating Patients Who Are Undergoing Surgery for Stage II or Stage III Rectal Cancer | completed | Phase 3 | 598 | UNICANCEROTHER | 1 | Feb 17, 2021 | clinicaltrials |
| NCT01318161 | Epidural Versus Patient-controlled Analgesia for Reduction in Long-term Mortality Following Colorectal Cancer Surgery(EPICOL) | terminated | Phase 3 | 221 | Örebro University, SwedenOTHER | 1 | Feb 16, 2021 | clinicaltrials |
| NCT04103697 | Neoadjuvant Chemotherapy in Patients With Intermediate Risk Upper and Mid Rectal Cancer(RuCorT-01) | unknown | Phase 3 | 560 | Blokhin's Russian Cancer Research CenterOTHER | 1 | Feb 9, 2021 | clinicaltrials |
| NCT04134897 | Neoadjuvant Chemotherapy in Patients With Moderate Risk Mid Rectal Cancer(RuCorT-02) | unknown | Phase 3 | 316 | Blokhin's Russian Cancer Research CenterOTHER | 1 | Feb 9, 2021 | clinicaltrials |
| NCT04135313 | Induction and Consolidation Chemotherapy in Patients With Locally Advanced CRM-positive Rectal Cancer(RuCorT-03) | unknown | Phase 3 | 540 | Blokhin's Russian Cancer Research CenterOTHER | 1 | Feb 9, 2021 | clinicaltrials |
| NCT03031444 | Perioperative Chemotherapy Plus Cetuximab Versus Chemotherapy Alone for High Risk Resectable Colorectal Liver Metastasis(PARECEC) | completed | Phase 2 / Phase 3 | 135 | Peking University Cancer Hospital & InstituteOTHER | 1 | Feb 1, 2021 | clinicaltrials |
| NCT03288987 | Comparing Efficacy and Safety of Stivant (AryoGen Bevacizumab) Versus Avastin in Metastatic Colorectal Cancer | completed | Phase 3 | 126 | AryoGen Pharmed Co.INDUSTRY | 1 | Jan 22, 2021 | clinicaltrials |
| NCT04712032 | Anastomotic Leakage and Value Of Indocyanine Green in Decreasing Leakage Rates(AVOID) | unknown | Phase 3 | 978 | Leiden University Medical CenterOTHER | 1 | Jan 15, 2021 | clinicaltrials |
| NCT03716518 | Herbal Treatment to Improve Chemotherapy Delivery(HATCHED) | unknown | Phase 3 | 400 | Xiyuan Hospital of China Academy of Chinese Medical SciencesOTHER | 1 | Jan 12, 2021 | clinicaltrials |
| NCT01224392 | Simultaneous Integrated Boost Preoperative Radiotherapy for Rectum Cancer(RectumSIB) | completed | Phase 3 | 156 | Universitair Ziekenhuis BrusselOTHER | 1 | Dec 30, 2020 | clinicaltrials |
| NCT04690283 | Yiqi Wenjing Prescriptions Preventive Efficacy of Oxaliplatin-induced Peripheral Neuropathy Clinical Trial(YWPPEOPNCT) | unknown | Phase 3 | 360 | Nanjing NingQi Medicine Science and Technology Co., Ltd.INDUSTRY | 0 | Dec 30, 2020 | clinicaltrials |
| NCT00023868 | Combination Chemotherapy With or Without Chemoembolization in Treating Patients With Colorectal Cancer Metastatic to the Liver (6655) | terminated | Phase 3 | — | American College of Radiology Imaging NetworkNETWORK | 1 | Dec 2, 2020 | clinicaltrials |
| NCT01500993 | Capecitabine in the Perioperative Treatment of Rectal Cancer(Rektum-III) | completed | Phase 3 | 401 | Universitätsmedizin MannheimOTHER | 1 | Nov 27, 2020 | clinicaltrials |
| NCT04642924 | SGM-101 in Locally Advanced and Recurrent Rectal Cancer(SGM-LARRC) | unknown | Phase 2 / Phase 3 | 203 | Leiden University Medical CenterOTHER | 1 | Nov 24, 2020 | clinicaltrials |
| NCT01955837 | Study of Trifluridine/Tipiracil (TAS-102) in Patients With Metastatic Colorectal Cancer in Asia(TERRA) | completed | Phase 3 | 406 | Taiho Pharmaceutical Co., Ltd.INDUSTRY | 3 | Nov 17, 2020 | clinicaltrials |
| NCT03909724 | Pulsatile High-dose Sunitinib Versus TAS-102 in Patients With Metastatic Colorectal Carcinoma (mCRC)(SUNRISE-CRC) | unknown | Phase 2 / Phase 3 | 60 | Amsterdam UMC, location VUmcOTHER | 1 | Nov 13, 2020 | clinicaltrials |
| NCT00265811 | Combination Chemotherapy With or Without Cetuximab in Treating Patients With Stage III Colon Cancer That Was Completely Removed By Surgery | completed | Phase 3 | 2,559 | Federation Francophone de Cancerologie DigestiveOTHER | 1 | Nov 9, 2020 | clinicaltrials |
| NCT04525326 | Conversion Therapy of RAS/BRAF Wild-Type Right-sided Colon Cancer Patients With Initially Unresectable Liver Metastases | unknown | Phase 3 | 584 | Fudan UniversityOTHER | 0 | Aug 25, 2020 | clinicaltrials |
| NCT04509635 | Cetuximab Re-challenge for Colorectal Cancer Liver Metastasis | unknown | Phase 3 | 50 | Fudan UniversityOTHER | 0 | Aug 12, 2020 | clinicaltrials |
| NCT04089631 | Circulating Tumour DNA Based Decision for Adjuvant Treatment in Colon Cancer Stage II Evaluation(CIRCULATE) | unknown | Phase 3 | 4,812 | Technische Universität DresdenOTHER | 1 | Aug 6, 2020 | clinicaltrials |
| NCT01164722 | Infrared Coagulator Ablation or Observation in Preventing Anal Cancer in HIV-Positive Patients With Anal Neoplasia | completed | Phase 3 | 120 | AIDS Malignancy ConsortiumNETWORK | 1 | Aug 4, 2020 | clinicaltrials |
| NCT03565354 | Efficacy of Preoperative Intravenous Iron in Anaemic Colorectal Cancer Surgical Patients | completed | Phase 3 | 40 | Prince of Wales Hospital, Shatin, Hong KongOTHER | 1 | Jul 20, 2020 | clinicaltrials |
| NCT02453490 | Compare Efficacy and Safety of Raltitrexed-based and 5fu-based Neoadjuvant Chemotherapy for Colorectal Liver Metastasis | terminated | Phase 3 | 360 | Zhejiang UniversityOTHER | 1 | Jul 14, 2020 | clinicaltrials |
| NCT04370925 | Efficacy of HIPEC in Patients With Colorectal Cancer at High Risk of Peritoneal Carcinomatosis | unknown | Phase 3 | 688 | Affiliated Cancer Hospital & Institute of Guangzhou Medical UniversityOTHER | 1 | Jun 16, 2020 | clinicaltrials |
| NCT03300609 | 5-FU Based Maintenance Therapy in RAS Wild Type Metastatic Colorectal Cancer After Induction With FOLFOX Plus Panitumumab | terminated | Phase 3 | 4 | University of Southern CaliforniaOTHER | 1 | Jun 11, 2020 | clinicaltrials |
| NCT04416854 | The Value of Palliative Primary Tumor Resection in Metastatic Colon Cancer | unknown | Phase 3 | 627 | Fudan UniversityOTHER | 1 | Jun 4, 2020 | clinicaltrials |
| NCT02371304 | Rectal Preserving Treatment for Early Rectal Cancer. A Multi-centred Randomised Trial of Radical Surgery Versus Adjuvant Chemoradiotherapy After Local Excision for Early Rectal Cancers(TESAR) | unknown | Phase 3 | 302 | Amsterdam UMC, location VUmcOTHER | 1 | May 21, 2020 | clinicaltrials |
| NCT00726622 | Laparoscopic-Assisted Resection or Open Resection in Treating Patients With Rectal Cancer | completed | Phase 3 | 486 | Alliance for Clinical Trials in OncologyOTHER | 2 | May 7, 2020 | clinicaltrials |
| NCT00003594 | Combination Chemotherapy in Treating Patients With Advanced Colorectal Cancer | completed | Phase 3 | 1,691 | Alliance for Clinical Trials in OncologyOTHER | 4 | Apr 29, 2020 | clinicaltrials |
| NCT04342676 | Lymph Node Ratio and Kras Mutation in R Colon Cancer | completed | Phase 3 | 433 | Mansoura UniversityOTHER | 1 | Apr 13, 2020 | clinicaltrials |
Data updated 23 days agoSource updated Jan 18, 2022source: clinicaltrials