Subtype
Malignant Large Intestinal Neoplasm
CI-CAN-00003173Explore in graph →
1,622 active trials21 approved drugs383 evidence items
- NCIt
- C215202
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Subtype
CI-CAN-00003173Explore in graph →
Clinical trials
7,502 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
Computedformula ci-trial-intel-v1 · interventional studies · entity + NCIt descendants · hover a figure for its formulaCompare cancersTerminated studies (742)
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT04201717 | Intracorporeal Anastomosis Versus Extracorporeal Anastomosis for Left Colon Cancer | active not recruiting | N/A | 350 | Jilin UniversityOTHER | 1 | May 7, 2025 | clinicaltrials |
| NCT06090994 | Prevention of Recurrence and Metastasis of Colorectal Cancer by Comparing Huaier With Capecitabine Monotherapy | recruiting | Phase 4 | 756 | Fudan UniversityOTHER | 1 | May 7, 2025 | clinicaltrials |
| NCT02983578 |
| Danvatirsen and Durvalumab in Treating Patients With Advanced and Refractory Pancreatic, Non-Small Cell Lung Cancer, and Mismatch Repair Deficient Colorectal Cancer |
| active not recruiting |
| Phase 2 |
| 39 |
| M.D. Anderson Cancer CenterOTHER |
| 1 |
| May 6, 2025 |
| clinicaltrials |
| NCT05179824 | Tempus Priority Study: A Pan-tumor Observational Study | active not recruiting | — | 1,000 | Tempus AIINDUSTRY | 1 | May 6, 2025 | clinicaltrials |
| NCT05234177 | Tempus CRC Surveillance Study: A ctDNA Biomarker Profiling Study of Patients With CRC Using NGS Assays | recruiting | — | 300 | Tempus AIINDUSTRY | 1 | May 6, 2025 | clinicaltrials |
| NCT06959693 | A Clinical Study to Evaluate the Efficacy and Safety of Envafolimab Combined With Cetuxima-βand mFOLFOX6 in Patients With MSS, RAS/BRAF Wild-Type Metastatic Colorectal Cancer (mCRC) | not yet recruiting | Phase 2 / Phase 3 | 590 | Sun Yat-sen UniversityOTHER | 1 | May 6, 2025 | clinicaltrials |
| NCT06949982 | Efficacy And Safety Of Hydroxychloroquine Combined With Methotrexate, Capecitabine And Bevacizumab Vs. Regorafenib In Participants With Refractory Metastatic Colorectal Cancer With Mutations In RAS Genes(x-МАР) | recruiting | Phase 2 | 60 | Sergey Orlov, MDOTHER | 1 | May 4, 2025 | clinicaltrials |
| NCT06956976 | Preservation Vs. Dissection of No. 253 Lymph Nodes of Robotic Resection for Mid/Low Rectal Cancer(REAL2) | not yet recruiting | N/A | 1,596 | Fudan UniversityOTHER | 1 | May 4, 2025 | clinicaltrials |
| NCT06307938 | Circulating Tumor DNA in Patients Summoned for Colonoscopy; - a Liquid Biopsy for Detection, Characterization, Individualized Treatment and Follow-up of Colorectal Cancer(CoLiQ) | recruiting | — | 3,000 | Helse Nord-Trøndelag HFOTHER | 1 | Apr 30, 2025 | clinicaltrials |
| NCT06944548 | Evaluation of the Effect of Adapted Physical Activity on the Modification of Lipid Metabolism During Chemotherapy for Metastatic COLorectal Cancer(APACOL) | not yet recruiting | Phase 2 | 54 | Centre Georges Francois LeclercOTHER | 1 | Apr 30, 2025 | clinicaltrials |
| NCT05965531 | Treating Locally Advanced Rectal Cancer With TAS-102 Chemotherapy Plus Neoadjuvant Radiotherapy(TASLARC) | recruiting | Phase 2 | 65 | Sun Yat-sen UniversityOTHER | 1 | Apr 29, 2025 | clinicaltrials |
| NCT06783244 | Low Versus Standard Intraabdominal Pressure in Robot-assisted Colorectal Cancer Surgery(LIPS) | recruiting | N/A | 200 | Victoria RosbergOTHER | 1 | Apr 29, 2025 | clinicaltrials |
| NCT06948539 | To Evaluate the Tolerability and Pharmacokinetics of TQB2101 for Injection in Patients With Advanced Malignant Tumors | not yet recruiting | Phase 1 | 66 | Chia Tai Tianqing Pharmaceutical Group Nanjing Shunxin Pharmaceutical Co., Ltd.INDUSTRY | 1 | Apr 29, 2025 | clinicaltrials |
| NCT04713007 | Improving Quality of Life for Colon Cancer Patients and Their Caregivers | active not recruiting | N/A | 60 | University of HawaiiOTHER | 1 | Apr 27, 2025 | clinicaltrials |
| NCT05167071 | HBM4003 Combine With Toripalimab in Patients With Advanced NEN and Other Solid Tumors Study | active not recruiting | Phase 1 | 53 | Harbour BioMed (Guangzhou) Co. Ltd.INDUSTRY | 1 | Apr 27, 2025 | clinicaltrials |
| NCT06940778 | LIQUID BIOPSY FOCUSING ON CIRCULATING TUMOR CELLS AND CIRCULATING TUMOR DNA AS PRECISION MEDICINE IN GASTROINTESTINAL TUMORS(BLENTI) | active not recruiting | — | 273 | Hospital do CoracaoOTHER | 1 | Apr 27, 2025 | clinicaltrials |
| NCT06940921 | SBRT-LDRT-Cadonilimab for Advanced Gastric, Colorectal and Ovarian Cancers With Peritoneal Metastases | active not recruiting | Phase 1 / Phase 2 | 26 | Zhang TaoOTHER | 1 | Apr 27, 2025 | clinicaltrials |
| NCT06946004 | Normobaric Oxygen Therapy in Colorectal Cancer Patients(NBO-ONCO) | not yet recruiting | N/A | 254 | 4th Military Clinical Hospital with Polyclinic, PolandOTHER | 1 | Apr 27, 2025 | clinicaltrials |
| NCT05736731 | A Study to Evaluate the Safety and Efficacy of A2B530, a Logic-gated CAR T, in Participants With Solid Tumors That Express CEA and Have Lost HLA-A*02 Expression(EVEREST-1) | active not recruiting | Phase 1 / Phase 2 | 160 | A2 Biotherapeutics Inc.INDUSTRY | 1 | Apr 25, 2025 | clinicaltrials |
| NCT06621173 | A Clinical Trial Evaluating the Safety and Efficacy of Intravenous HNF4α SrRNA in Treating Metastatic CRC Patients | recruiting | Early Phase 1 | 9 | Shanghai Changzheng HospitalOTHER | 1 | Apr 24, 2025 | clinicaltrials |
| NCT06822413 | Raman Spectroscopy-Based Deep Learning Model for Early Pan-Cancer Early Diagnosis | recruiting | — | 600 | Second Affiliated Hospital, Zhejiang University, School of MedicineOTHER | 1 | Apr 24, 2025 | clinicaltrials |
| NCT06943690 | Safety and Efficacy Study of Single-port Robotic Versus Multi-port Robotic Radical Rectal Cancer Surgery | not yet recruiting | N/A | 212 | Ruijin HospitalOTHER | 1 | Apr 24, 2025 | clinicaltrials |
| NCT06940102 | Real-World Study on Nano-Crystalline Megestrol Acetate for Cachexia in TKI-Treated Advanced Digestive Tumors | recruiting | — | 120 | Changchun GeneScience Pharmaceutical Co., Ltd.INDUSTRY | 1 | Apr 23, 2025 | clinicaltrials |
| NCT06938490 | Study of Colorectal Anastomosis Failures With First Sigmoid or Left Colonic Artery Preservation With D3 Lymphadenectomy(COLAP-D3) | not yet recruiting | N/A | 778 | the BELOOSTROV Clinic of High TechnologiesNETWORK | 1 | Apr 22, 2025 | clinicaltrials |
| NCT06935708 | Intrathecal Morphine Versus Epidural Analgesia for Open Colon Surgery | recruiting | Phase 4 | 98 | Meri MircetaOTHER | 1 | Apr 20, 2025 | clinicaltrials |
| NCT03428477 | EPA for Metastasis Trial 2(EMT2) | active not recruiting | Phase 3 | 418 | Mark A Hull, PhD FRCPOTHER | 1 | Apr 18, 2025 | clinicaltrials |
| NCT05239338 | Preserving Fertility After Colorectal Cancer Study(PREFACE) | recruiting | — | 1,000 | Andreana Holowatyj, PhD, MSCIOTHER | 1 | Apr 18, 2025 | clinicaltrials |
| NCT06923345 | Modified Long-Course Radiotherapy Followed by Chemotherapy and PD-1 Inhibitor for MSS/pMMR High-risk Mid/Low LARC (MODIFI-RC-I) | recruiting | Phase 2 | 80 | Sixth Affiliated Hospital, Sun Yat-sen UniversityOTHER | 1 | Apr 18, 2025 | clinicaltrials |
| NCT06931808 | Intestinal Microbiota Transplantation, Radiochemotherapy and Sintilimab in Localized Advanced Colon Cancer | enrolling by invitation | Phase 4 | 20 | First Affiliated Hospital of Ningbo UniversityNETWORK | 1 | Apr 17, 2025 | clinicaltrials |
| NCT06931873 | Neoadjuvant Radiochemotherapy Combined With QL1706 for Low Rectal Cancer | not yet recruiting | Early Phase 1 | 60 | Changhai HospitalOTHER | 0 | Apr 17, 2025 | clinicaltrials |
| NCT03908788 | Detection of the Emergence of RAS (Rat Sarcoma Viral Oncogene Homolog) Mutations in Circulating DNA (Deoxyribonucleic Acid) in Patients With mCRC (Metastatic Colorectal Cancer) During Treatment With Anti-EGFR (Epidermal Growth Factor Receptor) Therapy(EmutRAS) | active not recruiting | N/A | 130 | Institut du Cancer de Montpellier - Val d'AurelleOTHER | 1 | Apr 16, 2025 | clinicaltrials |
| NCT06926374 | Prospective Evaluation of Cornerstone Robotics Sentire Surgical System in Major Gastrointestinal and Urologic Surgery | recruiting | N/A | 90 | Chinese University of Hong KongOTHER | 1 | Apr 16, 2025 | clinicaltrials |
| NCT04980287 | Mesogastrium Metastasis in Colon Cancer | recruiting | — | 50 | Jichao QinOTHER | 1 | Apr 10, 2025 | clinicaltrials |
| NCT05275374 | XP-102 and XP-102 in Combination With Trametinib in Advanced Solid Tumor Patients With a BRAF V600 Mutation(ENHANCE) | not yet recruiting | Phase 1 / Phase 2 | 221 | Xynomic Pharmaceuticals, Inc.INDUSTRY | 0 | Apr 10, 2025 | clinicaltrials |
| NCT06251297 | Feasibility and Benefits of Reflexology in the Prevention of Neuropathy Induced by Oxaliplatin in Colorectal Cancer(FIRENOX) | recruiting | N/A | 40 | University Hospital, ToulouseOTHER | 1 | Apr 10, 2025 | clinicaltrials |
| NCT06678919 | AGMT Metastatic Colorectal Cancer Registry (mCRC) Third Line and Beyond | recruiting | — | 500 | Arbeitsgemeinschaft medikamentoese TumortherapieOTHER | 1 | Apr 10, 2025 | clinicaltrials |
| NCT06718543 | Neoadjuvant Short-Course Radiotherapy With or Without Chemotherapy and AK112 in Locally Advanced Rectal Cancer(TRIUNITE-03) | recruiting | Phase 2 | 100 | fan liOTHER | 1 | Apr 10, 2025 | clinicaltrials |
| NCT06621563 | Phase Ib Trial of HS-20117 in Combination With Other Drugs in Advanced Solid Tumors(HS-20117) | recruiting | Phase 1 | 780 | Hansoh BioMedical R&D CompanyINDUSTRY | 1 | Apr 9, 2025 | clinicaltrials |
| NCT06740357 | Implementation of a Tumor Response Assessment Program Integrating the Shared Medical Decision Into the Organ Preservation Strategy for Rectal Cancer Patients(EVAREC) | recruiting | N/A | 270 | Centre Hospitalier Universitaire DijonOTHER | 1 | Apr 9, 2025 | clinicaltrials |
| NCT06919510 | A Phase ll Study of Neoadjuvant Short-course Radiotherapy Followed by Ivonescimab and Chemotherapy in pMMR/MSS Locally Advanced Rectal Cancer | not yet recruiting | Phase 2 | 90 | Sun Yat-sen UniversityOTHER | 0 | Apr 9, 2025 | clinicaltrials |
| NCT06920082 | Progressive Muscle Relaxation Exercises on Sleep, Fatigue and Pain in Pancreatic and Colon Cancer Patients | active not recruiting | N/A | 60 | Istanbul Sabahattin Zaim UniversityOTHER | 1 | Apr 9, 2025 | clinicaltrials |
| NCT06630793 | IMRT Versus IMPT With Concurrent Chemotherapy for Locally Advanced Anal Canal Cancer(IMPAC) | recruiting | N/A | 108 | Tata Memorial CentreOTHER | 1 | Apr 8, 2025 | clinicaltrials |
| NCT05710809 | The SaVe Project-Sarcopenia and Vertigo in Aging Patients With Colorectal Cancer(SaVe) | recruiting | N/A | 150 | Rigshospitalet, DenmarkOTHER | 1 | Apr 6, 2025 | clinicaltrials |
| NCT06649123 | Triple Assay of Rectal Mucus in the Diagnosis of Colorectal Cancer(TRIOMIC) | recruiting | — | 6,600 | Origin SciencesINDUSTRY | 1 | Apr 4, 2025 | clinicaltrials |
| NCT05646511 | TNT of SCRT+CAPOX vs SCRT+CAPOXIRI for Locally Advanced Rectal Cancer(ENSEMBLE) | recruiting | Phase 3 | 608 | National Cancer Center Hospital EastOTHER | 1 | Apr 3, 2025 | clinicaltrials |
| NCT04025541 | Analysis of Circulating Tumor Markers in Blood(ALCINA2) | recruiting | N/A | 992 | Institut du Cancer de Montpellier - Val d'AurelleOTHER | 1 | Apr 2, 2025 | clinicaltrials |
| NCT06056804 | Neoadjuvant Chemoradiotherapy Combined With PD-1 Inhibitor and Thymalfasin for pMMR/MSS Locally Advanced Mid-low Rectal Cancer | active not recruiting | Phase 2 | 20 | Beijing Friendship HospitalOTHER | 1 | Apr 2, 2025 | clinicaltrials |
| NCT06223022 | Nurse-led Proactive Telephone Follow-up With Patients After Completion of Primary Cancer Treatment | enrolling by invitation | N/A | 512 | Umeå UniversityOTHER | 1 | Apr 2, 2025 | clinicaltrials |
| NCT05784688 | Study of TU2218 in Combination With KEYTRUDA®(Pembrolizumab) in Patients With Advanced Solid Tumors | recruiting | Phase 1 / Phase 2 | 140 | TiumBio Co., Ltd.INDUSTRY | 2 | Mar 30, 2025 | clinicaltrials |
Data updated 24 days agoSource updated May 7, 2025source: clinicaltrials