Clinical trial · Interventional
Feasibility and Benefits of Reflexology in the Prevention of Neuropathy Induced by Oxaliplatin in Colorectal Cancer
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The management of colorectal cancer often requires oxaliplatin-based chemotherapy, either as part of curative treatment plans or exclusively in palliative situations. Oxaliplatin therefore plays a key role in the management of colorectal cancer. In addition to its digestive and hematological toxicity, oxaliplatin frequently induces chronic, often limiting, sensitive peripheral neuropathy. Only early discontinuation of oxaliplatin can limit the risk of clinically limiting neurotoxicity (grade ≥ 3). In oncology, managing the side-effects of treatment is an essential objective of supportive care, and is open to a variety of complementary medicines, including reflexology. This technique, derived from traditional Chinese medicine, involves stimulating reflex points on the arch of the foot.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Colorectal Cancer | Malignant Colorectal Neoplasm | CURATED_BROADER | 0.80 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Foot reflexology | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- type
- EXPERIMENTAL
- label
- Reflexology session
- description
- Patients included in the study and treated with oxaliplatin based regiment will receive 30-min of a standard reflexology session during each infusion for a maximum of 12 sessions over 6 months).
- interventionNames
- Other: Foot reflexology
Primary outcomes (1)
- measure
- number of sessions performed
- timeFrame
- 6 months
- description
- at least 50% of patients included and realized at least 70% of reflexology sessions over the 6-month treatment.
Secondary outcomes (1)
- measure
- concordance of peripheral neuropathy evaluation
- timeFrame
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Age\>18 years treated for colorectal cancer in Digestive Oncology service Rangueil hospital * Initiation of intravenous oxaliplatin chemotherapy at 85 mg/m² on a bimonthly schedule. * Ability to understand and answer a self-questionnaire. * Life expectancy egal or over 12 weeks * Signed informed consent form Exclusion Criteria: * Pre-existing motor and/or sensitive neuropathy. * Reflexology treatment within the last 6 months. * Contraindication to reflexology: venous thrombosis, trauma, wound or metastasis of the foot. * Patient covered by a legal protection scheme.
References
Publications (0)
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