Subtype
Malignant Large Intestinal Neoplasm
CI-CAN-00003173Explore in graph →
1,622 active trials21 approved drugs383 evidence items
- NCIt
- C215202
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Subtype
CI-CAN-00003173Explore in graph →
Clinical trials
7,502 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
Computedformula ci-trial-intel-v1 · interventional studies · entity + NCIt descendants · hover a figure for its formulaCompare cancersTerminated studies (742)
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT00673322 | Trial of Second Generation Designer T Cells in Colorectal Carcinoma | terminated | Phase 1 | 1 | Roger Williams Medical CenterOTHER | 1 | Jun 17, 2016 | clinicaltrials |
| NCT02575508 | Pan FGFR Kinase Inhibitor BGJ398 and Combination Chemotherapy in Treating Patients With Untreated Metastatic Pancreatic Cancer | withdrawn | Phase 1 / Phase 2 | 0 | Roswell Park Cancer InstituteOTHER | 1 | May 20, 2016 | clinicaltrials |
| NCT01115790 | A Phase 1 Study in Participants With Advanced Cancer | completed | Phase 1 | 150 | Eli Lilly and CompanyINDUSTRY | 1 | May 10, 2016 | clinicaltrials |
| NCT01675128 | ISIS 183750 With Irinotecan for Advanced Solid Tumors or Colorectal Cancer | completed | Phase 1 / Phase 2 | 24 | National Cancer Institute (NCI)NIH | 1 | Apr 25, 2016 | clinicaltrials |
| NCT02453464 | A Phase Ib Study of Humanized Anti-VEGF Monoclonal Antibody (Sevacizumab) Injection Plus FOLFIRI in Chinese Patients With Metastatic Colorectal Cancer | unknown | Phase 1 | 36 | Jiangsu Simcere Pharmaceutical Co., Ltd.INDUSTRY | 1 | Apr 20, 2016 | clinicaltrials |
| NCT00563316 | Effect of Panitumumab on the Pharmacokinetics of Irinotecan | completed | Phase 1 | 28 | AmgenINDUSTRY | 2 | Apr 12, 2016 | clinicaltrials |
| NCT00558051 | Alpha-type-1 Dendritic Cell-based Vaccines in Patients With Metastatic Colorectal Cancer | completed | Phase 1 | 15 | Pawel KalinskiOTHER | 1 | Apr 1, 2016 | clinicaltrials |
| NCT01008475 | EMD 525797 in Combination With Cetuximab and Irinotecan in K-ras Wild Type Metastatic Colorectal Cancer(POSEIDON) | completed | Phase 1 / Phase 2 | 232 | Merck KGaA, Darmstadt, GermanyINDUSTRY | 12 | Mar 30, 2016 | clinicaltrials |
| NCT02720926 | Study of TKI 258 in Combination With Xeloda and Oxaliplatin in Advanced Colorectal and Gastric Cancer | terminated | Phase 1 | 3 | National Cancer Centre, SingaporeOTHER | 1 | Mar 28, 2016 | clinicaltrials |
| NCT01626963 | Single-port Versus Conventional Laparoscopic Colorectal Surgery | unknown | Phase 1 / Phase 2 | 50 | North Tees and Hartlepool NHS Foundation TrustOTHER | 1 | Mar 24, 2016 | clinicaltrials |
| NCT00353262 | A Study of Xeloda (Capecitabine) in Combination With Oxaliplatin in Patients With Metastatic Colorectal Cancer. | completed | Phase 1 | 36 | Hoffmann-La RocheINDUSTRY | 1 | Mar 4, 2016 | clinicaltrials |
| NCT01554969 | Phase I Trial of Ganetespib, Capecitabine, and Radiation in Rectal Cancer | completed | Phase 1 | 16 | Emory UniversityOTHER | 1 | Feb 22, 2016 | clinicaltrials |
| NCT00920868 | XAD - Xelox (Capecitabine + Oxaliplatin) + Bevacizumab + Dasatinib(XAD) | completed | Phase 1 | 22 | Herbert Hurwitz, MDOTHER | 1 | Feb 3, 2016 | clinicaltrials |
| NCT01203969 | Safety and Efficacy of Single Port Laparoscopic Surgery in Colon Cancer | completed | Phase 1 | 62 | Kyunghee University Medical CenterOTHER | 1 | Feb 3, 2016 | clinicaltrials |
| NCT02020291 | Phase I Study to Evaluate Safety, Tolerability, Anti-Tumour Activity and PK Profiles of Foxy-5 in Metastatic Breast, Colon or Prostate Cancer | completed | Phase 1 | 31 | WntResearch ABINDUSTRY | 1 | Feb 2, 2016 | clinicaltrials |
| NCT00876954 | Preoperative Hyperthermia in Major Abdominal Surgery Patients | completed | Phase 1 / Phase 2 | 20 | Medical University of ViennaOTHER | 1 | Jan 21, 2016 | clinicaltrials |
| NCT01791309 | Vemurafenib and Panitumumab Combination Therapy in Patients With BRAF V600E Mutated Metastatic Colorectal Cancer | completed | Phase 1 | 16 | Memorial Sloan Kettering Cancer CenterOTHER | 1 | Jan 5, 2016 | clinicaltrials |
| NCT02489916 | Donafenib Monotherapy for Previously Treated Metastatic Colorectal Cancer | completed | Phase 1 / Phase 2 | 47 | Suzhou Zelgen Biopharmaceuticals Co.,LtdINDUSTRY | 1 | Jan 5, 2016 | clinicaltrials |
| NCT00574977 | Safety Study of Modified Vaccinia Virus to Cancer | completed | Phase 1 | 26 | David BartlettOTHER | 1 | Dec 28, 2015 | clinicaltrials |
| NCT00581815 | Spectroscopy With Surface Coils and Decoupling | completed | Phase 1 | 582 | Memorial Sloan Kettering Cancer CenterOTHER | 1 | Dec 28, 2015 | clinicaltrials |
| NCT01816659 | An Open-Labeled Pilot Study of Biomarker Response Following Short-Term Exposure to Metformin | terminated | Phase 1 | 3 | M.D. Anderson Cancer CenterOTHER | 1 | Nov 18, 2015 | clinicaltrials |
| NCT00594984 | Phase I/II Combination With Irinotecan- Erbitux | completed | Phase 1 / Phase 2 | 38 | Bristol-Myers SquibbINDUSTRY | 7 | Nov 4, 2015 | clinicaltrials |
| NCT00207155 | An Exploratory Pharmacogenomic Study of Monotherapy Erbitux in Subjects With Metastic Colorectal Cancer | completed | Phase 1 | 110 | Eli Lilly and CompanyINDUSTRY | 3 | Oct 28, 2015 | clinicaltrials |
| NCT01516489 | Improving Fecal Occult Blood Test Completion Rates Among Veterans | completed | Phase 1 / Phase 2 | 1,549 | Corporal Michael J. Crescenz VA Medical CenterFED | 1 | Oct 26, 2015 | clinicaltrials |
| NCT01164215 | Biomarker-Guided Fluorouracil in Treating Patients With Colorectal Cancer Receiving Combination Chemotherapy | completed | Phase 1 | 76 | UNC Lineberger Comprehensive Cancer CenterOTHER | 1 | Oct 9, 2015 | clinicaltrials |
| NCT01882946 | Safety and Efficacy Study of DCVax-Direct in Solid Tumors | unknown | Phase 1 / Phase 2 | 60 | Northwest BiotherapeuticsINDUSTRY | 1 | Oct 7, 2015 | clinicaltrials |
| NCT00397384 | Erlotinib Hydrochloride and Cetuximab in Treating Patients With Advanced Gastrointestinal Cancer, Head and Neck Cancer, Non-Small Cell Lung Cancer, or Colorectal Cancer | completed | Phase 1 | 43 | National Cancer Institute (NCI)NIH | 1 | Sep 30, 2015 | clinicaltrials |
| NCT00244348 | Hepatic Artery Infusion With Oxaliplatin | withdrawn | Phase 1 / Phase 2 | 0 | Medical College of WisconsinOTHER | 1 | Aug 27, 2015 | clinicaltrials |
| NCT01300858 | A Study of the Safety and Biological Activity of Intraperitoneal (IP) EGEN-001 Administered Alone and in Combination With Standard Chemotherapy in Colorectal Peritoneal Carcinomatosis Patients | terminated | Phase 1 / Phase 2 | 4 | EGEN, Inc.INDUSTRY | 1 | Jul 13, 2015 | clinicaltrials |
| NCT01461148 | Vaccination Against MSI Colorectal Cancer | completed | Phase 1 / Phase 2 | 22 | Oryx GmbH & Co. KGINDUSTRY | 1 | Jun 23, 2015 | clinicaltrials |
| NCT00099346 | MK0457 (an Aurora Kinase Inhibitor) Study in Patients With Advanced Colorectal Cancer and Other Advanced Solid Tumors (0457-001) | terminated | Phase 1 | — | Merck Sharp & Dohme LLCINDUSTRY | 0 | Jun 17, 2015 | clinicaltrials |
| NCT01205022 | Radiolabeled Monoclonal Antibody Therapy, Combination Chemotherapy, and Bevacizumab in Treating Patients With Metastatic Colorectal Cancer | completed | Phase 1 | 3 | City of Hope Medical CenterOTHER | 1 | Jun 8, 2015 | clinicaltrials |
| NCT01294826 | Study of AUY922 and Cetuximab in Patients With KRAS Wild-Type Metastatic Colorectal Cancer | completed | Phase 1 | 20 | Swedish Medical CenterOTHER | 1 | Jun 8, 2015 | clinicaltrials |
| NCT01238965 | Panobinostat and Fluorouracil Followed By Leucovorin Calcium in Treating Patients With Stage IV Colorectal Cancer Who Did Not Respond to Previous Fluorouracil-Based Chemotherapy | terminated | Phase 1 | 7 | University of Southern CaliforniaOTHER | 1 | May 27, 2015 | clinicaltrials |
| NCT01110941 | Feasibility Study of SOL (S-1,Oral Leucovorin,and Oxaliplatin) for Colorectal Cancer in China(SCI-101) | completed | Phase 1 / Phase 2 | 20 | Shen LinOTHER | 1 | May 19, 2015 | clinicaltrials |
| NCT01198535 | Phase I Study of Cetuximab With RO4929097 in Metastatic Colorectal Cancer | terminated | Phase 1 | 60 | National Cancer Institute (NCI)NIH | 1 | May 18, 2015 | clinicaltrials |
| NCT00522665 | Phase I/Randomized Phase II Study of Second Line Therapy With Irinotecan + Cetuximab +/- RAD001 for Colorectal Cancer | completed | Phase 1 / Phase 2 | 41 | Hoosier Cancer Research NetworkOTHER | 1 | May 15, 2015 | clinicaltrials |
| NCT00778830 | Study Evaluating the Safety and Efficacy of FOLFIRI Plus Cetuximab or FOLFOX Plus Cetuximab as First-line Therapy in Subjects With KRAS Wild-type Metastatic Colorectal Cancer (APEC-Study)(APEC) | completed | Phase 1 / Phase 2 | 289 | Merck KGaA, Darmstadt, GermanyINDUSTRY | 1 | May 14, 2015 | clinicaltrials |
| NCT00641615 | Peptide Vaccine and S-1/CPT-11 Therapy for Patients With Unresectable Advanced Colorectal Cancer | completed | Phase 1 | 18 | Kazuhiko YoshimatsuOTHER | 1 | May 12, 2015 | clinicaltrials |
| NCT00019110 | Vaccine Therapy in Treating Patients With Advanced or Recurrent Cancer | completed | Phase 1 | — | National Cancer Institute (NCI)NIH | 1 | Apr 29, 2015 | clinicaltrials |
| NCT00019435 | LMB-9 Immunotoxin in Treating Patients With Advanced Solid Tumors | completed | Phase 1 | — | National Cancer Institute (NCI)NIH | 1 | Apr 29, 2015 | clinicaltrials |
| NCT00019773 | Oxaliplatin Plus Capecitabine in Treating Patients With Colorectal, Appendix, or Small Bowel Cancer | completed | Phase 1 | — | National Cancer Institute (NCI)NIH | 1 | Apr 29, 2015 | clinicaltrials |
| NCT01916239 | Pomegranate Extract Supplementation in Colorectal Cancer Patients(POMEcolon) | completed | Phase 1 / Phase 2 | 60 | National Research Council, SpainOTHER_GOV | 1 | Apr 14, 2015 | clinicaltrials |
| NCT02211443 | Safety, Tolerability and Pharmacokinetics of Recombinant Anti-epidermal Growth Factor Receptor(EGFR) Monoclonal Antibody in Patients With Metastatic Colorectal Cancer | unknown | Phase 1 | 21 | Sinocelltech Ltd.INDUSTRY | 0 | Apr 9, 2015 | clinicaltrials |
| NCT01277406 | 4SC-201 (Resminostat) in Advanced Colorectal Carcinoma(SHORE) | completed | Phase 1 / Phase 2 | 17 | 4SC AGINDUSTRY | 1 | Apr 1, 2015 | clinicaltrials |
| NCT00551421 | Pertuzumab and Cetuximab in Treating Patients With Previously Treated Locally Advanced or Metastatic Colorectal Cancer | completed | Phase 1 / Phase 2 | 17 | National Cancer Institute (NCI)NIH | 1 | Mar 31, 2015 | clinicaltrials |
| NCT01440127 | Impact of Pretreatment With Metformin on Colorectal Cancer Stem Cells (CCSC) and Related Pharmacodynamic Markers | terminated | Phase 1 | 9 | Tufts Medical CenterOTHER | 1 | Mar 26, 2015 | clinicaltrials |
| NCT00753415 | A Study of V934/V935 Vaccine in Cancer Participants With Selected Solid Tumors (V934-002) | completed | Phase 1 | 37 | Merck Sharp & Dohme LLCINDUSTRY | 0 | Mar 17, 2015 | clinicaltrials |
| NCT00575640 | Hydralazine as a Demethylating Agent in Rectal Cancer | withdrawn | Phase 1 / Phase 2 | 0 | University of ArkansasOTHER | 0 | Mar 4, 2015 | clinicaltrials |
| NCT00543842 | Bevacizumab, Erlotinib, and Capecitabine for Locally Advanced Rectal Cancer | completed | Phase 1 | 19 | M.D. Anderson Cancer CenterOTHER | 1 | Feb 26, 2015 | clinicaltrials |
Data updated 23 days agoSource updated Jun 17, 2016source: clinicaltrials