Subtype
Malignant Large Intestinal Neoplasm
CI-CAN-00003173Explore in graph →
1,622 active trials21 approved drugs383 evidence items
- NCIt
- C215202
Loading cancer entity…
Loading cancer entity…
Subtype
CI-CAN-00003173Explore in graph →
Clinical trials
7,502 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
Computedformula ci-trial-intel-v1 · interventional studies · entity + NCIt descendants · hover a figure for its formulaCompare cancersTerminated studies (742)
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT00080951 | Irinotecan, Fluorouracil, Leucovorin, and Oxaliplatin as First-Line Therapy in Treating Patients With Metastatic Colorectal Cancer | completed | Phase 2 | 14 | Alliance for Clinical Trials in OncologyOTHER | 0 | Dec 7, 2016 | clinicaltrials |
| NCT02077777 | Chemopreventive Action of Mesalazine on Colorectal Cancer: a Pilot Study for an "in Vivo" Evaluation of the Molecular Effects on β-catenin Signaling Pathway. | completed | Phase 2 | 21 | SOFAR S.p.A.INDUSTRY | 1 | Dec 2, 2016 |
| clinicaltrials |
| NCT01549535 | Polyp Detection With The Peerscope System™ | completed | Phase 2 | 197 | PeerMedical Ltd.INDUSTRY | 3 | Nov 25, 2016 | clinicaltrials |
| NCT00362102 | A Phase II Study of Cetuximab Plus Irinotecan in Patients With EGFR-detectable Metastatic Colorectal Carcinoma | completed | Phase 2 | 38 | Eli Lilly and CompanyINDUSTRY | 0 | Nov 22, 2016 | clinicaltrials |
| NCT00912743 | Efficacy and Safety of Olaparib in Pretreated Patients With Measurable Colorectal Cancer, Stratified by Microsatellite Instability (MSI) Status | completed | Phase 2 | 33 | AstraZenecaINDUSTRY | 1 | Nov 9, 2016 | clinicaltrials |
| NCT00527111 | Pre-op Rectal ChemoRad +/- Cetuximab | completed | Phase 2 | 139 | US Oncology ResearchINDUSTRY | 1 | Nov 3, 2016 | clinicaltrials |
| NCT00048126 | A Study of Xeloda (Capecitabine) in Patients With Advanced and/or Metastatic Colorectal Cancer | completed | Phase 2 | 57 | Hoffmann-La RocheINDUSTRY | 1 | Nov 2, 2016 | clinicaltrials |
| NCT00048139 | A Study of Xeloda (Capecitabine) in Patients With Advanced and/or Metastatic Colorectal Cancer | completed | Phase 2 | 52 | Hoffmann-La RocheINDUSTRY | 1 | Nov 2, 2016 | clinicaltrials |
| NCT00700570 | A Study of Avastin (Bevacizumab) in Combination With XELOX in Patients With Metastatic Colorectal Cancer | completed | Phase 2 | 45 | Hoffmann-La RocheINDUSTRY | 1 | Nov 2, 2016 | clinicaltrials |
| NCT00778102 | A Study of Avastin (Bevacizumab) in Combination With mFOLFOX-6 or FOLFOXIRI in Patients With Metastatic Colorectal Cancer. | completed | Phase 2 | 80 | Hoffmann-La RocheINDUSTRY | 4 | Nov 2, 2016 | clinicaltrials |
| NCT00940303 | OPAL Study: A Study of Avastin (Bevacizumab) in Combination With FOLFOXIRI in Patients With Previously Untreated Metastatic Colorectal Cancer | completed | Phase 2 | 97 | Hoffmann-La RocheINDUSTRY | 1 | Nov 2, 2016 | clinicaltrials |
| NCT01652482 | Safety and Efficacy Study of MEHD7945A + FOLFIRI Versus Cetuximab + FOLFIRI as Second Line Therapy in Participants With KRAS Wild-Type Metastatic Colorectal Cancer (mCRC) | completed | Phase 2 | 135 | Genentech, Inc.INDUSTRY | 10 | Nov 2, 2016 | clinicaltrials |
| NCT00813605 | QUILT-2.018: Safety & Efficacy of FOLFIRI With AMG 479 or AMG 655 vs FOLFIRI Alone in KRAS-mutant Metastatic Colorectal Carcinoma | completed | Phase 2 | 155 | NantCell, Inc.INDUSTRY | 10 | Oct 27, 2016 | clinicaltrials |
| NCT01043484 | Safety and Efficacy Study to Compare Capecitabine + Bevacizumab Versus Capecitabine, Concomitantly With Radiotherapy as Neoadjuvant Treatment for Patients With Localized and Resectable Rectal Cancer(AVAXEL) | completed | Phase 2 | 90 | Spanish Cooperative Group for the Treatment of Digestive Tumours (TTD)OTHER | 1 | Oct 19, 2016 | clinicaltrials |
| NCT01569984 | Radiosensitization of AVASTIN® (Bevacizumab) With Stereotactic Body Radiotherapy for Colorectal Liver Metastasis(SBRT-Avastin) | completed | Phase 2 | 11 | Dr. Yoo-Joung KoOTHER | 1 | Oct 13, 2016 | clinicaltrials |
| NCT00454116 | A Phase II, Double Blind Study of 2 Doses of ZACTIMA™(ZD6474) in Combination With FOLFIRI vs FOLFIRI Alone for the Treatment of Colorectal Cancer in Patients | completed | Phase 2 | 106 | Genzyme, a Sanofi CompanyINDUSTRY | 6 | Oct 7, 2016 | clinicaltrials |
| NCT00278694 | Oxaliplatin and 5-FU Based Preoperative Chemoradiation(LARC-RRP) | completed | Phase 2 | 109 | Oslo University HospitalOTHER | 1 | Sep 29, 2016 | clinicaltrials |
| NCT01263171 | Oxaliplatin, Leucovorin, and Fluorouracil Before and After Radiation Therapy and Surgery in Treating Patients With Rectal Cancer That Can Be Removed by Surgery(COPERNICUS) | completed | Phase 2 | 60 | Cardiff UniversityOTHER | 1 | Sep 21, 2016 | clinicaltrials |
| NCT01269229 | A Trial of Neoadjuvant FOLFOX6 With Short Course Radiotherapy in Patients With Unresectable Rectal Cancer and Liver Metastasis | completed | Phase 2 | 32 | Yonsei UniversityOTHER | 1 | Sep 7, 2016 | clinicaltrials |
| NCT01399684 | A Study Evaluating the Efficacy and Safety of MEGF0444A Dosed to Progression in Combination With Bevacizumab and mFOLFOX-6 in Participants With Previously Untreated Metastatic Colorectal Cancer | completed | Phase 2 | 127 | Genentech, Inc.INDUSTRY | 5 | Aug 26, 2016 | clinicaltrials |
| NCT00796718 | A Study of Xeloda (Capecitabine) Plus Radiotherapy in Participants With Locally Advanced Rectal Cancer | completed | Phase 2 | 62 | Hoffmann-La RocheINDUSTRY | 1 | Aug 25, 2016 | clinicaltrials |
| NCT01344538 | Ginger for Colorectal Cancer Prevention | completed | Phase 2 | 30 | University of MichiganOTHER | 1 | Aug 11, 2016 | clinicaltrials |
| NCT01374425 | Study of Bevacizumab + mFOLFOX6 Versus Bevacizumab + FOLFIRI With Biomarker Stratification in Participants With Previously Untreated Metastatic Colorectal Cancer (mCRC)(MAVERICC) | completed | Phase 2 | 376 | Genentech, Inc.INDUSTRY | 7 | Aug 11, 2016 | clinicaltrials |
| NCT00588640 | Study of D-Methadone in Patients With Chronic Pain | completed | Phase 1 / Phase 2 | 10 | Memorial Sloan Kettering Cancer CenterOTHER | 1 | Aug 10, 2016 | clinicaltrials |
| NCT01696630 | Xenon Combined With Intraoperative Thoracic Epidural Analgesia | completed | Phase 2 | 31 | Centre Leon BerardOTHER | 1 | Aug 4, 2016 | clinicaltrials |
| NCT00033748 | Vaccine Therapy in Treating Patients With Colorectal Cancer Metastatic to the Liver | completed | Phase 2 | 56 | Alliance for Clinical Trials in OncologyOTHER | 1 | Jul 19, 2016 | clinicaltrials |
| NCT00336856 | Irinotecan and Cetuximab for Colorectal Cancer as Second Line Therapy | completed | Phase 2 | 35 | University of PittsburghOTHER | 1 | Jul 12, 2016 | clinicaltrials |
| NCT00003834 | Combination Chemotherapy in Treating Patients With Liver Metastases From Colorectal Cancer | completed | Phase 2 | 44 | Alliance for Clinical Trials in OncologyOTHER | 2 | Jul 6, 2016 | clinicaltrials |
| NCT00023751 | Surgery With or Without Chemotherapy and Radiation Therapy in TreatingPatients With Stage I Rectal Cancer | completed | Phase 2 | 320 | Alliance for Clinical Trials in OncologyOTHER | 3 | Jul 6, 2016 | clinicaltrials |
| NCT00063960 | Hepatic Arterial Infusion With Floxuridine and Systemic Irinotecan After Surgery in Treating Patients With Hepatic (Liver) Metastases From Colorectal Cancer | completed | Phase 2 | 94 | Alliance for Clinical Trials in OncologyOTHER | 1 | Jul 6, 2016 | clinicaltrials |
| NCT00311610 | Liposomal SN-38 in Treating Patients With Metastatic Colorectal Cancer | completed | Phase 2 | 30 | Alliance for Clinical Trials in OncologyOTHER | 1 | Jun 29, 2016 | clinicaltrials |
| NCT01086267 | Safety and Efficacy Study of BMS-908662 Alone or in Combination With Cetuximab in Subjects With K-RAS or B-RAF Mutation Positive Advanced or Metastatic Colorectal Cancer | completed | Phase 1 / Phase 2 | 17 | Bristol-Myers SquibbINDUSTRY | 2 | Jun 27, 2016 | clinicaltrials |
| NCT00931203 | Trial of Celecoxib With Preoperative Chemo- Radiation for Locally Advanced Rectal Cancer | completed | Phase 2 | 55 | National Health Research Institutes, TaiwanOTHER | 1 | May 4, 2016 | clinicaltrials |
| NCT01675128 | ISIS 183750 With Irinotecan for Advanced Solid Tumors or Colorectal Cancer | completed | Phase 1 / Phase 2 | 24 | National Cancer Institute (NCI)NIH | 1 | Apr 25, 2016 | clinicaltrials |
| NCT00022698 | Capecitabine and Irinotecan in Treating Patients With Locally Advanced, Recurrent, or Metastatic Colorectal Cancer | completed | Phase 2 | 67 | Hoffmann-La RocheINDUSTRY | 1 | Apr 15, 2016 | clinicaltrials |
| NCT01008475 | EMD 525797 in Combination With Cetuximab and Irinotecan in K-ras Wild Type Metastatic Colorectal Cancer(POSEIDON) | completed | Phase 1 / Phase 2 | 232 | Merck KGaA, Darmstadt, GermanyINDUSTRY | 12 | Mar 30, 2016 | clinicaltrials |
| NCT01821105 | 2 Phase Comparison of Pre-operative CT and PET Images for Metastatic Colorectal Cancer | completed | Phase 2 | 21 | Ohio State University Comprehensive Cancer CenterOTHER | 1 | Mar 2, 2016 | clinicaltrials |
| NCT00255229 | Study of Glutamine as Prophylaxis for Irinotecan Induced Diarrhea | completed | Phase 2 | 130 | AHS Cancer Control AlbertaOTHER | 1 | Feb 25, 2016 | clinicaltrials |
| NCT01290926 | Sorafenib Plus Capecitabine Efficacy Assessment in Patients With Advanced Pre-treated Colorectal Cancer(SoMore) | completed | Phase 2 | 97 | Jules Bordet InstituteOTHER | 1 | Feb 24, 2016 | clinicaltrials |
| NCT00332163 | Skin Toxicity Treatment in Metastatic Colorectal Cancer (mCRC) Patients Receiving Panitumumab + Irinotecan-based Therapy(STEPP) | completed | Phase 2 | 95 | AmgenINDUSTRY | 0 | Feb 23, 2016 | clinicaltrials |
| NCT00587964 | Phase II Trial of Stereotactic Radiosurgery Boost Following Surgical Resection for Brain Metastases | completed | Phase 2 | 51 | Memorial Sloan Kettering Cancer CenterOTHER | 1 | Feb 22, 2016 | clinicaltrials |
| NCT00479752 | Safety and Efficacy of Folfox4 + Weekly Cetuximab vs Folfox 4+Biweekly Cetuximab by Metastatic Colorectal Cancer(CORE 2) | completed | Phase 2 | 151 | Central European Cooperative Oncology GroupOTHER | 13 | Feb 18, 2016 | clinicaltrials |
| NCT00411450 | Panitumumab Regimen Evaluation in Colorectal Cancer to Estimate Primary Response to Treatment(PRECEPT) | completed | Phase 2 | 116 | AmgenINDUSTRY | 0 | Feb 15, 2016 | clinicaltrials |
| NCT01074216 | Vitamin D Levels in Stage IV Colorectal Cancer Patients | completed | Phase 2 | 45 | Memorial Sloan Kettering Cancer CenterOTHER | 1 | Feb 3, 2016 | clinicaltrials |
| NCT00835185 | Study of IMC-11F8 in Participants With Colorectal Cancer | completed | Phase 2 | 44 | Eli Lilly and CompanyINDUSTRY | 2 | Jan 29, 2016 | clinicaltrials |
| NCT00876954 | Preoperative Hyperthermia in Major Abdominal Surgery Patients | completed | Phase 1 / Phase 2 | 20 | Medical University of ViennaOTHER | 1 | Jan 21, 2016 | clinicaltrials |
| NCT01386242 | Recombinant Anti-tumor and Anti-virus Protein for Injection in Treatment of Metastatic Colorectal Cancer | completed | Phase 2 | 108 | The Affiliated Hospital of the Chinese Academy of Military Medical SciencesOTHER | 1 | Jan 5, 2016 | clinicaltrials |
| NCT02489916 | Donafenib Monotherapy for Previously Treated Metastatic Colorectal Cancer | completed | Phase 1 / Phase 2 | 47 | Suzhou Zelgen Biopharmaceuticals Co.,LtdINDUSTRY | 1 | Jan 5, 2016 | clinicaltrials |
| NCT00550589 | Cidofovir in Treating HIV-Infected Patients With High-Grade Squamous Intraepithelial Lesions of the Skin Near the Anus | completed | Phase 2 | 33 | AIDS Malignancy ConsortiumNETWORK | 1 | Dec 21, 2015 | clinicaltrials |
| NCT01022541 | Capecitabine and Oxaliplatin Plus Bevacizumab as Neoadjuvant Treatment for Untreated Unresectable Liver-only Metastases From Colorectal Cancer | completed | Phase 2 | 47 | Royal Marsden NHS Foundation TrustOTHER | 1 | Nov 25, 2015 | clinicaltrials |
Data updated 23 days agoSource updated Dec 7, 2016source: clinicaltrials