Subtype
Malignant Large Intestinal Neoplasm
CI-CAN-00003173Explore in graph →
1,622 active trials21 approved drugs383 evidence items
- NCIt
- C215202
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Subtype
CI-CAN-00003173Explore in graph →
Clinical trials
7,502 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
Computedformula ci-trial-intel-v1 · interventional studies · entity + NCIt descendants · hover a figure for its formulaCompare cancersTerminated studies (742)
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT06950996 | A Clinical Evaluation of AI Solutions Developed in the CHAIMELEON Project for Cancer: Prostate, Lung, Breast, Colon and Rectum | completed | — | 300 | Instituto de Investigacion Sanitaria La FeOTHER | 1 | Apr 30, 2025 | clinicaltrials |
| NCT04468607 | A Study of BLYG8824A in Participants With Locally Advanced or Metastatic Colorectal Cancer | completed | Phase 1 | 46 | Genentech, Inc.INDUSTRY | 3 | Apr 25, 2025 |
| NCT04491955 | Phase II Trial of Combination Immunotherapy in Subjects With Advanced Small Bowel and Colorectal Cancers | completed | Phase 2 | 32 | National Cancer Institute (NCI)NIH | 1 | Apr 24, 2025 | clinicaltrials |
| NCT03428958 | A Safety, Pharmacokinetic and Efficacy Study of NUC-3373 in Combination With Standard Agents Used in Colorectal Cancer Treatment | completed | Phase 1 / Phase 2 | 111 | NuCana plcOTHER | 3 | Apr 23, 2025 | clinicaltrials |
| NCT04705363 | A Sociolinguistic-enabled Web Application to Develop Precision Health Intervention for African Americans | completed | N/A | 751 | University of FloridaOTHER | 1 | Apr 18, 2025 | clinicaltrials |
| NCT02934529 | Metastatic Colorectal Cancer (RAS-wildtype) After Response to First-line Treatment With FOLFIR Plus Cetuximab(AIO-KRK-0114) | completed | Phase 3 | 673 | Ludwig-Maximilians - University of MunichOTHER | 1 | Apr 16, 2025 | clinicaltrials |
| NCT02990481 | A Phase 1 Study Evaluating the Safety of TRK-950 in Patients With Advanced Solid Tumors | completed | Phase 1 | 38 | Toray Industries, IncINDUSTRY | 2 | Apr 16, 2025 | clinicaltrials |
| NCT04441580 | Assessing the Additional Neoplasia Yield of Computer-aided Colonoscopy in a Screening Setting(GENIAL-CO) | completed | N/A | 900 | Fondazione Poliambulanza Istituto OspedalieroOTHER | 1 | Apr 10, 2025 | clinicaltrials |
| NCT04322539 | A Study of Efficacy and Safety of Fruquintinib (HMPL-013) in Participants With Metastatic Colorectal Cancer(FRESCO-2) | completed | Phase 3 | 691 | Hutchison Medipharma LimitedINDUSTRY | 14 | Apr 4, 2025 | clinicaltrials |
| NCT04582500 | Virtual Colonoscopy Using Omnipaque as a Contrast Agent | completed | — | 50 | Montefiore Medical CenterOTHER | 1 | Apr 4, 2025 | clinicaltrials |
| NCT03597581 | A Study of RGX-202-01 (Ompenaclid) as Combination Therapy in RAS Mutant Advanced Colorectal Cancer | completed | Phase 1 | 89 | Inspirna, Inc.INDUSTRY | 1 | Apr 3, 2025 | clinicaltrials |
| NCT05255588 | A Stool DNA-based SDC2 Methylation Test for the Early Detection of Colorectal Cancer | completed | — | 2,358 | Genomictree, Inc.INDUSTRY | 1 | Apr 3, 2025 | clinicaltrials |
| NCT03894618 | SL-279252 (PD1-Fc-OX40L) in Subjects With Advanced Solid Tumors or Lymphomas | completed | Phase 1 | 49 | Shattuck Labs, Inc.INDUSTRY | 4 | Apr 2, 2025 | clinicaltrials |
| NCT05742438 | Effects of Dexmedetomidine/Lidocaine/Intrathecal Morphine on Cancer Metastasis Biomarker After Colorectal Surgery | completed | N/A | 114 | Samsung Medical CenterOTHER | 1 | Apr 2, 2025 | clinicaltrials |
| NCT04761614 | Riluzole in Combination With mFOLFOX6 and Bevacizumab in Treating Patients With Metastatic Colorectal Cancer | completed | Phase 1 | 13 | Ning JinOTHER | 1 | Mar 28, 2025 | clinicaltrials |
| NCT05390398 | Study on Fatigue in Colorectal Cancer Survivors, a Lifestyle Intervention(SoFiT) | completed | N/A | 161 | Wageningen UniversityOTHER | 1 | Mar 28, 2025 | clinicaltrials |
| NCT06900686 | Clinical Application of PD-1 Inhibitor in Colorectal Cancer for Improving Survival | completed | — | 458 | Yanhong DengOTHER | 0 | Mar 28, 2025 | clinicaltrials |
| NCT03506321 | Comparison of the Benefit of Chromoendoscopy in Addition to High Definition White Light and Narrow Band Imaging for the Prediction of Submucosal Invasive Cancer in Colonic Lesions(LANS) | completed | N/A | 400 | Western Sydney Local Health DistrictOTHER | 1 | Mar 27, 2025 | clinicaltrials |
| NCT04138030 | Conventional Endoscopic Mucosal Resection Versus Cold Snare Endoscopic Mucosal Resection of Colonic Lateral Spreading Lesions - A Randomised Controlled Trial | completed | N/A | 182 | Western Sydney Local Health DistrictOTHER | 1 | Mar 27, 2025 | clinicaltrials |
| NCT06898359 | Role of Gut Microbiota in Neoadjuvant Radioimmunotherapy for MSS, Locally Advanced Rectal Cancer | completed | — | 29 | Yanhong DengOTHER | 1 | Mar 27, 2025 | clinicaltrials |
| NCT00059930 | Adjuvant Hepatic Arterial Infusion and Combination Chemotherapy in Treating Patients With Resectable Hepatic Metastases From Colorectal Cancer | completed | Phase 1 | 38 | Memorial Sloan Kettering Cancer CenterOTHER | 1 | Mar 26, 2025 | clinicaltrials |
| NCT02895464 | Feasibility of Home-based Preoperative Exercise in Older People | completed | N/A | 23 | Karolinska InstitutetOTHER | 1 | Mar 25, 2025 | clinicaltrials |
| NCT03724851 | Vactosertib in Combination with Pembrolizumab in Metastatic Colorectal or Gastric Cancer | completed | Phase 1 / Phase 2 | 120 | MedPacto, Inc.INDUSTRY | 1 | Mar 25, 2025 | clinicaltrials |
| NCT03195699 | Oral STAT3 Inhibitor, TTI-101, in Patients With Advanced Cancers | completed | Phase 1 | 64 | Tvardi Therapeutics, IncorporatedINDUSTRY | 1 | Mar 21, 2025 | clinicaltrials |
| NCT00200200 | Hepatic Arterial Infusion With Floxuridine and Dexamethasone Combination With Chemotherapy With/Without Bevacizumab for Hepatic Metastases From Colorectal Cancer | completed | Phase 2 | 73 | Memorial Sloan Kettering Cancer CenterOTHER | 1 | Mar 19, 2025 | clinicaltrials |
| NCT00545545 | Safety/Efficacy Study of Imprime PGG With Cetuximab in Patients With Recurrent/Progressive Colorectal Carcinoma | completed | Phase 1 / Phase 2 | 32 | HiberCell, Inc.INDUSTRY | 1 | Mar 19, 2025 | clinicaltrials |
| NCT02649790 | Study of the Safety, Tolerability and Efficacy of KPT-8602 in Participants With Relapsed/Refractory Cancer Indications | completed | Phase 1 / Phase 2 | 277 | Karyopharm Therapeutics IncINDUSTRY | 5 | Mar 19, 2025 | clinicaltrials |
| NCT04256707 | Relative Bioavailability/Bioequivalence of Different Formulations of Selinexor, the Impact of Hepatic Impairment on Selinexor Pharmacokinetics, Tolerability and Antitumor Activity of Selinexor Combination Treatment(SPRINT) | completed | Phase 1 / Phase 2 | 126 | Karyopharm Therapeutics IncINDUSTRY | 1 | Mar 19, 2025 | clinicaltrials |
| NCT00906997 | Colorectal Cancer Screening in Average-risk Population: Immunochemical Fecal Occult Blood Testing Versus Colonoscopy | completed | N/A | 55,498 | Hospital Clinic of BarcelonaOTHER | 1 | Mar 18, 2025 | clinicaltrials |
| NCT05943288 | Safety and Efficacy of the Olympus CADe System in Real-time Colonoscopy(EuroCADe) | completed | — | 850 | Olympus Europe SE & Co. KGINDUSTRY | 4 | Mar 18, 2025 | clinicaltrials |
| NCT04072198 | Nivolumab Plus FOLFOXIRI/Bevacizumab in First Line Chemotherapy of Advanced Colorectal Cancer RASm/BRAFm Patients(NIVACOR) | completed | Phase 2 | 73 | Gruppo Oncologico Italiano di Ricerca ClinicaOTHER | 1 | Mar 13, 2025 | clinicaltrials |
| NCT04636619 | Clinical Trial Evaluating External Evaluation and Training on the Incomplete Resection (POLIPEVA Study)(POLIPEVA) | completed | N/A | 1,920 | Hospital del Rio HortegaOTHER | 1 | Mar 13, 2025 | clinicaltrials |
| NCT05402592 | The Effect of Oral Carbohydrate Administration on Postoperative Well-being | completed | N/A | 50 | Muğla Sıtkı Koçman UniversityOTHER | 1 | Mar 13, 2025 | clinicaltrials |
| NCT06865586 | A Comparative Study of Tumor Specific Mesocolic Excision and Complete Mesocolic Excision for Right Sided Colon Cancer : Asian Multicenter Retrospective Study | completed | — | 3,326 | Asan Medical CenterOTHER | 1 | Mar 10, 2025 | clinicaltrials |
| NCT03761017 | MGD019 DART® Protein in Unresectable/Metastatic Cancer | completed | Phase 1 | 162 | MacroGenicsINDUSTRY | 5 | Mar 6, 2025 | clinicaltrials |
| NCT05697198 | PRospective REgistry of Advanced Stage CancER (PREFER) Patients to Assess Prevalence of Actionable Biomarkers and Driver Mutations to Address Disparities in Precision Medicine(PREFER) | completed | — | 1,429 | Labcorp Corporation of America Holdings, IncINDUSTRY | 1 | Mar 6, 2025 | clinicaltrials |
| NCT05740137 | Adenoma Detection Rate in Artificial Intelligence-assisted Colonoscopy | completed | N/A | 795 | Ismail GögenurOTHER | 1 | Mar 6, 2025 | clinicaltrials |
| NCT03829410 | Onvansertib in Combination With FOLFIRI and Bevacizumab for Second Line Treatment of Metastatic Colorectal Cancer Patients With a KRAS Mutation | completed | Phase 1 / Phase 2 | 68 | Cardiff OncologyINDUSTRY | 1 | Mar 4, 2025 | clinicaltrials |
| NCT01226979 | Study of High-Dose-Rate Endorectal Brachytherapy (HDRBT) in the Treatment of Locally Advanced Low Rectal Cancer(HDRBT) | completed | N/A | 16 | Sidney Kimmel Comprehensive Cancer Center at Johns HopkinsOTHER | 1 | Feb 28, 2025 | clinicaltrials |
| NCT03396926 | Pembrolizumab, Capecitabine, and Bevacizumab for Treating Colorectal Cancer | completed | Phase 2 | 44 | University of California, San FranciscoOTHER | 1 | Feb 28, 2025 | clinicaltrials |
| NCT03058289 | A Phase 1/2 Safety Study of Intratumorally Dosed INT230-6(IT-01) | completed | Phase 1 / Phase 2 | 111 | Intensity Therapeutics, Inc.INDUSTRY | 2 | Feb 27, 2025 | clinicaltrials |
| NCT06168825 | Mind Over Matter for Black and African American Women: A Single Arm Trial Examining Feasibility and Acceptability of a Supportive Intervention(MOM) | completed | — | 40 | Inova Health Care ServicesOTHER | 1 | Feb 27, 2025 | clinicaltrials |
| NCT05131815 | The BurnAlong Pilot Study for Adolescent and Young Adult Cancer Survivors | completed | N/A | 8 | Cedars-Sinai Medical CenterOTHER | 1 | Feb 26, 2025 | clinicaltrials |
| NCT06029010 | An Observational Study to Learn More About the Long-Term Responses to Treatment With Regorafenib in Patients With Metastatic Colorectal Cancer in the United States(COLONGER) | completed | — | 2,326 | BayerINDUSTRY | 1 | Feb 26, 2025 | clinicaltrials |
| NCT01643070 | Preoperative CRT With or Without Induction Chemotherapy for Rectal Cancer With Liver Metastases | completed | Phase 2 | 38 | Asan Medical CenterOTHER | 1 | Feb 25, 2025 | clinicaltrials |
| NCT04380337 | Organ Preservation Program Using Short-Course Radiation & FOLFOXIRI in Rectal Cancer | completed | Phase 2 | 38 | Stanford UniversityOTHER | 1 | Feb 25, 2025 | clinicaltrials |
| NCT04947020 | DataBase for Analysis of Rectal Cancer Oncological Results(BARO) | completed | — | 2,443 | Jagiellonian UniversityOTHER | 1 | Feb 25, 2025 | clinicaltrials |
| NCT05512793 | Clinical Validation of PolyDeep: an Artificial Intelligence-based Computer-aided Polyp Detection (CADe) and Characterization (CADx) System. Polydeep Advance 2. | completed | N/A | 260 | Fundacin Biomedica Galicia SurOTHER | 1 | Feb 24, 2025 | clinicaltrials |
| NCT05513261 | Clinical Validation of PolyDeep: an Artificial Intelligence-based Computer-aided Polyp Detection (CADe) and Characterization (CADx) System. Polydeep Advance 3 | completed | N/A | 857 | Fundacin Biomedica Galicia SurOTHER | 1 | Feb 24, 2025 | clinicaltrials |
Data updated 23 days agoSource updated Apr 30, 2025source: clinicaltrials