Subtype
Malignant Glioma
CI-CAN-00003164Explore in graph →
589 active trials3 approved drugs67 evidence items
- NCIt
- C4822
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Subtype
CI-CAN-00003164Explore in graph →
Clinical trials
2,053 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
Computedformula ci-trial-intel-v1 · interventional studies · entity + NCIt descendants · hover a figure for its formulaCompare cancersTerminated studies (325)
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT02395692 | Methoxyamine and Temozolomide in Treating Patients With Recurrent Glioblastoma | terminated | Phase 2 | 20 | National Cancer Institute (NCI)NIH | 1 | Apr 4, 2019 | clinicaltrials |
| NCT03403803 | Prognosis and Therapeutic Biomarkers for Glioblastoma Patients | terminated | — | 10 | Baylor Research InstituteOTHER | 1 | Mar 27, 2019 | clinicaltrials |
| NCT01186406 |
| Gliadel, XRT, Temodar, Avastin Followed by Avastin, Temodar for Newly Diagnosed Glioblastoma Multiforme (GBM) |
| terminated |
| Phase 2 |
| 41 |
| Duke UniversityOTHER |
| 1 |
| Feb 15, 2019 |
| clinicaltrials |
| NCT01044966 | A Study of Intraventricular Liposomal Encapsulated Ara-C (DepoCyt) in Patients With Recurrent Glioblastoma | terminated | Phase 1 / Phase 2 | 12 | Medical University of South CarolinaOTHER | 1 | Feb 12, 2019 | clinicaltrials |
| NCT03293888 | Spectral Analysis Probe to Identify Glioblastoma Cells | terminated | — | 12 | University of OklahomaOTHER | 1 | Jan 25, 2019 | clinicaltrials |
| NCT01432171 | Lacosamide in Preventing Seizures in Participants With Malignant Glioma | terminated | N/A | 37 | M.D. Anderson Cancer CenterOTHER | 1 | Dec 19, 2018 | clinicaltrials |
| NCT00734526 | Phase I Portion of Phase I/II Sorafenib With Radiation and Temozolomide in Newly Diagnosed Glioblastoma or Gliosarcoma | terminated | Phase 1 | 18 | M.D. Anderson Cancer CenterOTHER | 1 | Nov 9, 2018 | clinicaltrials |
| NCT00895960 | Dasatinib Plus Radiation Therapy/Temozolomide in Newly-Diagnosed Glioblastoma | terminated | Phase 1 | 16 | M.D. Anderson Cancer CenterOTHER | 1 | Nov 8, 2018 | clinicaltrials |
| NCT02850744 | Study to Evaluate the Efficacy, Safety, Pharmacokinetics and Pharmacodynamic Effects of PQR309 in Glioblastoma Patients | terminated | Phase 2 | 10 | PIQUR Therapeutics AGINDUSTRY | 1 | Oct 19, 2018 | clinicaltrials |
| NCT01868906 | FMISO-PET in Brain Tumors and SCS Effect(FMISOPETSCS) | terminated | Phase 2 | 6 | Bernardino Clavo, MD, PhDOTHER | 1 | Aug 24, 2018 | clinicaltrials |
| NCT02062372 | Spatial Analysis and Validation of Glioblastoma on 7 T MRI | terminated | N/A | 5 | Maastricht Radiation OncologyOTHER | 1 | Aug 17, 2018 | clinicaltrials |
| NCT02176720 | Response Monitoring Trial in Patients With Suspected Recurrence of Glioblastoma | terminated | Phase 1 | 31 | The Methodist Hospital Research InstituteOTHER | 1 | Aug 17, 2018 | clinicaltrials |
| NCT01103375 | Erlotinib Hydrochloride and Isotretinoin in Treating Patients With Recurrent Malignant Glioma | terminated | Phase 1 | 5 | Wake Forest University Health SciencesOTHER | 1 | Aug 1, 2018 | clinicaltrials |
| NCT01575275 | Aminolevulinic Acid in Visualizing a Tumor During Surgery in Patients With Glioblastoma Multiforme | terminated | Phase 2 | 8 | Michael Vogelbaum, MD, PhDOTHER | 1 | Jul 31, 2018 | clinicaltrials |
| NCT01836549 | Imetelstat Sodium in Treating Younger Patients With Recurrent or Refractory Brain Tumors | terminated | Phase 2 | 43 | Pediatric Brain Tumor ConsortiumNETWORK | 1 | Jul 20, 2018 | clinicaltrials |
| NCT01281982 | (11C)dLop as a Marker of P-Glycoprotein Function in Patients With Gliomas | terminated | — | 2 | National Cancer Institute (NCI)NIH | 1 | Jul 5, 2018 | clinicaltrials |
| NCT01086345 | Radiosurgery Plus Bevacizumab in Glioblastoma | terminated | Early Phase 1 | 9 | Case Comprehensive Cancer CenterOTHER | 1 | Jul 3, 2018 | clinicaltrials |
| NCT01234805 | Yoga Therapy in Treating Patients With Malignant Brain Tumors | terminated | N/A | 9 | Wake Forest University Health SciencesOTHER | 1 | Jul 3, 2018 | clinicaltrials |
| NCT02375334 | Adherence Monitoring System in Managing Myelosuppression in Patients With Newly Diagnosed Malignant Gliomas Receiving Temozolomide and Radiation Therapy | terminated | — | 18 | Wake Forest University Health SciencesOTHER | 1 | Jul 3, 2018 | clinicaltrials |
| NCT00990496 | A Study Using Allogenic-Cytomegalovirus (CMV) Specific Cells for Glioblastoma Multiforme (GBM) | terminated | Phase 1 | 25 | Milton S. Hershey Medical CenterOTHER | 0 | May 2, 2018 | clinicaltrials |
| NCT02227576 | Prevention of Thrombocytopenia in Glioblastoma Patients(PLATUM) | terminated | Phase 2 | 20 | University Hospital, LilleOTHER | 1 | Apr 25, 2018 | clinicaltrials |
| NCT01702792 | Derivation of Tumor Specific Hybridomas | terminated | Phase 1 | 1 | Dartmouth-Hitchcock Medical CenterOTHER | 0 | Apr 4, 2018 | clinicaltrials |
| NCT02654041 | Study of Induction of Hypothyroxinemia Adjunct to Conventional Therapies in GBM Patients | terminated | Phase 2 | 3 | Musli Thyropeutics Ltd.INDUSTRY | 1 | Mar 22, 2018 | clinicaltrials |
| NCT02254954 | Clinical Study on Macitentan, RT and TMZ Concurrent Therapy Followed by Maintenance Macitentan and TMZ in Newly Diagnosed Glioblastoma | terminated | Phase 1 | 30 | ActelionINDUSTRY | 1 | Feb 27, 2018 | clinicaltrials |
| NCT02047214 | Safety & Efficacy Study of TPI 287 + Avastin in Adults With Glioblastoma That Progressed Following Prior Avastin Therapy | terminated | Phase 2 | 17 | Cortice Biosciences, Inc.INDUSTRY | 1 | Jan 31, 2018 | clinicaltrials |
| NCT01339039 | Plerixafor (AMD3100) and Bevacizumab for Recurrent High-Grade Glioma | terminated | Phase 1 | 26 | Patrick Y. Wen, MDOTHER | 1 | Nov 17, 2017 | clinicaltrials |
| NCT02510950 | Neoepitope-based Personalized Vaccine Approach in Patients With Newly Diagnosed Glioblastoma | terminated | Phase 1 | 1 | Washington University School of MedicineOTHER | 1 | Nov 17, 2017 | clinicaltrials |
| NCT01666600 | NOA-12: BIBF1120 and R-RT in Glioblastoma | terminated | Phase 1 / Phase 2 | 63 | Prof. Dr. Wolfgang WickOTHER | 1 | Nov 1, 2017 | clinicaltrials |
| NCT02329795 | Image-derived Prediction of Response to Chemo-radiation in Glioblastoma(IDEPREG) | terminated | — | 16 | Rigshospitalet, DenmarkOTHER | 1 | Oct 12, 2017 | clinicaltrials |
| NCT01508117 | Phase II Axitinib (AG-013736) in Elderly Glioblastoma Multiforme (GBM) Patients | terminated | Phase 2 | 1 | University of CincinnatiOTHER | 1 | Sep 19, 2017 | clinicaltrials |
| NCT01526837 | Bevacizumab (Avastin) Into the Tumor Resection Cavity in Subjects With Glioblastoma Multiforme at First Recurrence | terminated | Phase 1 | 1 | Brain & Spine Surgeons of New YorkOTHER | 1 | Jul 12, 2017 | clinicaltrials |
| NCT00112866 | Cilengitide in Treating Patients Who Are Undergoing Surgery for Recurrent or Progressive Glioblastoma Multiforme | terminated | Phase 2 | 30 | National Cancer Institute (NCI)NIH | 1 | Jun 14, 2017 | clinicaltrials |
| NCT02039778 | Stem Cell Radiotherapy and Temozolomide for Newly Diagnosed High-grade Glioma(STRONG) | terminated | N/A | 4 | Beth Israel Medical CenterOTHER | 1 | Jun 5, 2017 | clinicaltrials |
| NCT01310855 | Cediranib Maleate With or Without Gefitinib in Treating Patients With Recurrent or Progressive Glioblastoma | terminated | Phase 2 | 38 | University College, LondonOTHER | 1 | May 31, 2017 | clinicaltrials |
| NCT02648633 | Stereotactic Radiosurgery With Nivolumab and Valproate in Patients With Recurrent Glioblastoma | terminated | Phase 1 | 4 | University of VirginiaOTHER | 1 | May 31, 2017 | clinicaltrials |
| NCT02129335 | Stress, Exercise Behavior and Survival in Patients With Newly Diagnosed Glioblastoma and in a Close Partner(TOGETHER) | terminated | — | 12 | University Hospital, Basel, SwitzerlandOTHER | 1 | May 17, 2017 | clinicaltrials |
| NCT01122901 | Gamma-Secretase/Notch Signalling Pathway Inhibitor RO4929097 in Treating Patients With Recurrent or Progressive Glioblastoma | terminated | Phase 2 | 47 | National Cancer Institute (NCI)NIH | 1 | May 3, 2017 | clinicaltrials |
| NCT01996527 | 3T MRI Biomarkers of Glioma Treatment Response | terminated | Early Phase 1 | 7 | Vanderbilt-Ingram Cancer CenterOTHER | 1 | Apr 17, 2017 | clinicaltrials |
| NCT02967380 | Gadobutrol Versus Gadopentetate Dimeglumine or Gadobenate Dimeglumine Before DCE-MRI in Diagnosing Patients With Multiple Sclerosis, Grade II-IV Glioma, or Brain Metastases | terminated | N/A | 14 | University of Southern CaliforniaOTHER | 1 | Mar 27, 2017 | clinicaltrials |
| NCT02175745 | 18F-FDOPA PET/CT or PET/MRI in Measuring Tumors in Patients With Newly-Diagnosed or Recurrent Gliomas | terminated | N/A | 2 | Erik MittraOTHER | 1 | Mar 20, 2017 | clinicaltrials |
| NCT01902771 | Dendritic Cell Vaccine Therapy With In Situ Maturation in Pediatric Brain Tumors | terminated | Phase 1 | 1 | Edward ZigaOTHER | 1 | Mar 10, 2017 | clinicaltrials |
| NCT00456612 | Radiosurgery for Glioblastoma Multiforme | terminated | Phase 1 / Phase 2 | 4 | Beth Israel Deaconess Medical CenterOTHER | 1 | Mar 6, 2017 | clinicaltrials |
| NCT00171938 | Open-label Trial of Imatinib Mesylate in Patients With Unresectable Recurrent Glioblastoma Multiforme Expressing PDGFR (Platelet Derived Growth Factor Receptors) | terminated | Phase 2 | 30 | NovartisINDUSTRY | 1 | Feb 24, 2017 | clinicaltrials |
| NCT01148966 | Aminolevulinic Acid During Surgery in Treating Patients With Malignant Brain Tumors | terminated | Phase 1 | 6 | University of WashingtonOTHER | 1 | Feb 15, 2017 | clinicaltrials |
| NCT02025231 | Image Guided Reirradiation of High-grade Glioma | terminated | Phase 1 / Phase 2 | 31 | Rigshospitalet, DenmarkOTHER | 2 | Feb 8, 2017 | clinicaltrials |
| NCT02394665 | Dose Escalated MRSI Guided Radiation Therapy in Glioblastoma | terminated | Phase 2 | 1 | University of MiamiOTHER | 1 | Jan 5, 2017 | clinicaltrials |
| NCT02841332 | Multimodal Imaging Analysis During Treatment With Bevacizumab in Patients With Recurrent Glioblastoma(IMAGLIO) | terminated | N/A | 6 | University Hospital, ToulouseOTHER | 1 | Dec 20, 2016 | clinicaltrials |
| NCT00473408 | The Effect of Radiotherapy and Temozolomide on the Tumor Vasculature and Stem Cells in Human High-grade Astrocytomas(Gliomstudien) | terminated | — | 1 | Haukeland University HospitalOTHER | 1 | Dec 6, 2016 | clinicaltrials |
| NCT02371031 | FDOPA-PET/MRI for the Pre-operative Evaluation of Gliomas | terminated | Phase 1 | 11 | Washington University School of MedicineOTHER | 1 | Nov 30, 2016 | clinicaltrials |
Data updated 22 days agoSource updated Apr 4, 2019source: clinicaltrials