Cancer
Malignant Esophageal Neoplasm
CI-CAN-00001127Explore in graph →
Top-level518 active trials6 approved drugs12 evidence items
Loading cancer entity…
Loading cancer entity…
Cancer
CI-CAN-00001127Explore in graph →
Clinical trials
1,926 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
Computedformula ci-trial-intel-v1 · interventional studies · entity + NCIt descendants · hover a figure for its formulaCompare cancersTerminated studies (169)
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT05542680 | Study on the Design and Application of Special Semi Recumbent Cushion for Postoperative Patients With Esophageal Cancer | completed | N/A | 134 | Cancer Institute and Hospital, Chinese Academy of Medical SciencesOTHER | 1 | Jun 27, 2024 | clinicaltrials |
| NCT05688761 | Nordic Gastric and Esophageal Tumor Study(NordGETS) | completed | — | 900,000 | Karolinska InstitutetOTHER | 1 | Jun 24, 2024 |
| clinicaltrials |
| NCT06314516 | Influence of Nutrition and Sarcopenia on Esophageal Cancer Outcomes(INSPECT) | completed | — | 1,717 | Benaroya Research InstituteOTHER | 1 | May 24, 2024 | clinicaltrials |
| NCT06424210 | The Role of Surgery for Esophageal Cancer With Metastatic Disease (M1) | completed | — | 163 | National Taiwan University HospitalOTHER | 1 | May 22, 2024 | clinicaltrials |
| NCT04207918 | A Phase II Study of Chemoradiotherapy With Nimotuzumab in Unresectable Esophageal Cancer | completed | Phase 2 | 55 | Cancer Institute and Hospital, Chinese Academy of Medical SciencesOTHER | 1 | May 16, 2024 | clinicaltrials |
| NCT06381583 | A Liquid Biopsy for High-risk Pre-cancer Screening of Esophageal Adenocarcinoma(EMERALD) | completed | — | 658 | City of Hope Medical CenterOTHER | 1 | May 10, 2024 | clinicaltrials |
| NCT03243734 | trūFreeze® Palliative Esophageal Cancer | completed | N/A | 49 | US Endoscopy Group Inc.INDUSTRY | 1 | May 8, 2024 | clinicaltrials |
| NCT04192695 | Esophageal Squamous Cell Cancer Surveillance With Cytosponge | completed | N/A | 178 | Centre of Postgraduate Medical EducationOTHER | 1 | May 8, 2024 | clinicaltrials |
| NCT05523960 | Mechanical Bowel Preparation Versus no Bowel Preparation for Esophageal Cancer Surgery | completed | N/A | 652 | Cancer Institute and Hospital, Chinese Academy of Medical SciencesOTHER | 1 | May 7, 2024 | clinicaltrials |
| NCT03165994 | APX005M With Concurrent Chemoradiation for Resectable Esophageal and Gastroesophageal Junction Cancers | completed | Phase 2 | 34 | Apexigen America, Inc.INDUSTRY | 1 | May 2, 2024 | clinicaltrials |
| NCT03468634 | Raman Probe for In-vivo Diagnostics (During Oesophageal) Endoscopy(RaPIDE) | completed | N/A | 25 | University of ExeterOTHER | 1 | Apr 25, 2024 | clinicaltrials |
| NCT05082948 | Migration Rates of Sutured vs Non-sutured Esophageal Stent Placement | completed | N/A | 46 | West Virginia UniversityOTHER | 1 | Apr 23, 2024 | clinicaltrials |
| NCT02129933 | VEGF-targeted Fluorescence Near-Infrared (NIR) Endoscopy in (Pre)Malignant Esophageal Lesions(VICE) | completed | Phase 1 | 14 | University Medical Center GroningenOTHER | 1 | Apr 16, 2024 | clinicaltrials |
| NCT03205501 | Molecular Fluorescence Endoscopy of (Pre)Malignant Esophageal Lesions(EAGLE) | completed | Phase 1 | 15 | University Medical Center GroningenOTHER | 1 | Apr 16, 2024 | clinicaltrials |
| NCT04656392 | Early Detection of Barrett's Esophagus in Participants With Reflux Symptoms in Primary Care(ELECTRONIC) | completed | N/A | 449 | Radboud University Medical CenterOTHER | 1 | Apr 16, 2024 | clinicaltrials |
| NCT03060642 | The Microenvironment in Barrett's Esophagus(BETRNet2) | completed | — | 155 | Columbia UniversityOTHER | 1 | Apr 5, 2024 | clinicaltrials |
| NCT04896242 | Multimodal Assesment of Acute Cardiac Toxicity Induced by Thoracic Radiotherapy in Cancer Patients | completed | — | 47 | Pontificia Universidad Catolica de ChileOTHER | 1 | Apr 4, 2024 | clinicaltrials |
| NCT03329950 | A Study of CDX-1140 (CD40) as Monotherapy or in Combination in Patients With Advanced Malignancies | completed | Phase 1 | 132 | Celldex TherapeuticsINDUSTRY | 1 | Mar 28, 2024 | clinicaltrials |
| NCT02735239 | Study of Anti-PD-L1 in Combination With Chemo(Radio)Therapy for Oesophageal Cancer | completed | Phase 1 / Phase 2 | 73 | Ludwig Institute for Cancer ResearchOTHER | 1 | Mar 22, 2024 | clinicaltrials |
| NCT04314349 | Radiogenomics in Aerodigestive Tract Cancers | completed | — | 139 | Buddhist Tzu Chi General HospitalOTHER | 1 | Mar 22, 2024 | clinicaltrials |
| NCT05030870 | Capnographic Monitoring in Gastrointestinal Endoscopy for Elderly Patients(CapnoGI) | completed | N/A | 1,800 | RenJi HospitalOTHER | 1 | Mar 19, 2024 | clinicaltrials |
| NCT03339843 | Multiorgan Metabolic Imaging Response Assessment of Abemaciclib(MiMe-A) | completed | Phase 2 | 85 | Jules Bordet InstituteOTHER | 2 | Mar 15, 2024 | clinicaltrials |
| NCT02812680 | The Utility of Circulating Tumour Cells and Plasma microRNA in Esophageal Adenocarcinoma | completed | — | 84 | University Health Network, TorontoOTHER | 1 | Mar 8, 2024 | clinicaltrials |
| NCT02497664 | Optimizing (Breathing) Techniques for Radiotherapy of Esophageal and Lung Carcinomas(ABC) | completed | N/A | 22 | University Medical Center GroningenOTHER | 1 | Feb 28, 2024 | clinicaltrials |
| NCT05069766 | Preoperative Marking of the Oral Resection Margin in Esophageal Cancer With a Surgical Fiducial Marker - First Experiences | completed | N/A | 10 | Rigshospitalet, DenmarkOTHER | 1 | Feb 23, 2024 | clinicaltrials |
| NCT02830594 | Pembrolizumab and Palliative Radiation Therapy in Treating Patients With Metastatic Esophagus, Stomach, or Gastroesophageal Junction Cancer | completed | Phase 2 | 14 | City of Hope Medical CenterOTHER | 1 | Feb 20, 2024 | clinicaltrials |
| NCT01691625 | Concurrent Chemoradiation With or Without DC-CIK Immunotherapy in Treating Locally Advanced Esophageal Cancer | completed | N/A | 50 | Capital Medical UniversityOTHER | 1 | Feb 7, 2024 | clinicaltrials |
| NCT06190652 | Real-world Experience of ICIs Plus Chemotherapy With or Without Radiotherapy for Advanced ESCC.(REICRAE) | completed | — | 728 | Tianjin Medical University Cancer Institute and HospitalOTHER | 1 | Feb 5, 2024 | clinicaltrials |
| NCT06241066 | The Prognostic Value of Tertiary Lymphatic Structure in Esophageal Squamous Cell Carcinoma | completed | — | 359 | Tianjin Medical University Cancer Institute and HospitalOTHER | 1 | Feb 5, 2024 | clinicaltrials |
| NCT06241079 | Multi-institutional Analysis of Survival and Recurrence Patterns of Different Pathological Regression Types After Neoadjuvant Chemoradiotherapy or Radiotherapy for Esophageal Squamous Cell Carcinoma | completed | — | 582 | Tianjin Medical University Cancer Institute and HospitalOTHER | 0 | Feb 5, 2024 | clinicaltrials |
| NCT06219031 | A Study of the Tumor Microenvironment Affecting the Efficacy of Immunotherapy for Esophageal Cancer | completed | — | 22 | Renmin Hospital of Wuhan UniversityOTHER | 1 | Jan 26, 2024 | clinicaltrials |
| NCT03196232 | Epacadostat and Pembrolizumab in Treating Patients With Metastatic or Unresectable Gastroesophageal Junction or Gastric Cancer | completed | Phase 2 | 3 | George Albert FisherOTHER | 1 | Jan 23, 2024 | clinicaltrials |
| NCT03543813 | PROCLAIM-CX-2029: A Trial to Find Safe and Active Doses of an Investigational Drug CX-2029 for Patients With Solid Tumors or DLBCL | completed | Phase 1 / Phase 2 | 133 | CytomX TherapeuticsINDUSTRY | 4 | Jan 23, 2024 | clinicaltrials |
| NCT03099382 | Study of SHR-1210 Versus Investigator's Choice of Chemotherapy for Participants With Advanced Esophageal Cancer | completed | Phase 3 | 457 | Jiangsu HengRui Medicine Co., Ltd.INDUSTRY | 1 | Jan 22, 2024 | clinicaltrials |
| NCT04568200 | Study of Anti-PD-L1 in Combination With Chemo(Radio)Therapy for Resectable Esophageal Squamous Cell Carcinoma | completed | Phase 2 | 60 | Peking Union Medical College HospitalOTHER | 1 | Jan 22, 2024 | clinicaltrials |
| NCT03600831 | Postoperative Concurrent Chemoradiotherapy Versus Radiotherapy Alone for Patients With Locoregionally Advanced Esophageal Squamous Cell Carcinoma | completed | Phase 2 / Phase 3 | 434 | Huai'an First People's HospitalOTHER | 1 | Jan 9, 2024 | clinicaltrials |
| NCT06184841 | HAIC Combined Sintilimab for Liver Metastasis From Esophageal Squamous Cell Carcinoma | completed | Phase 1 | 25 | Peking University Cancer Hospital & InstituteOTHER | 1 | Dec 28, 2023 | clinicaltrials |
| NCT02379039 | Multimodal Monitoring of Radiotherapy Response in Squamous Cell Cancer(MORRIS) | completed | — | 118 | Umeå UniversityOTHER | 1 | Dec 22, 2023 | clinicaltrials |
| NCT02916511 | Study of Extensive Clinical Target Volumes in Postoperative Radiotherapy Concurrent With Chemotherapy for Esophageal Squamous Cell Carcinoma(ESO-Shanghai9) | completed | Phase 2 | 70 | Fudan UniversityOTHER | 1 | Dec 22, 2023 | clinicaltrials |
| NCT03783936 | Trial of mFOLFOX6 + Trastuzumab + Avelumab in Gastric and Esophageal Adenocarcinomas | completed | Phase 2 | 18 | Ashwin SomasundaramOTHER | 1 | Dec 19, 2023 | clinicaltrials |
| NCT06165094 | Effect of Cervical Paraesophageal Lymph Node Metastasis Versus Supraclavicular Lymph Node Metastasis on the Overall Survival of Patients With Thoracic Esophageal Squamous Cell Carcinoma: An Observational Study(ECPLNMvsSLNM) | completed | — | 122 | Sichuan Cancer Hospital and Research InstituteOTHER | 1 | Dec 11, 2023 | clinicaltrials |
| NCT01416077 | Decreasing Postoperative Complications by Goal-Directed Fluid Therapy During Esophageal Resection | completed | Phase 4 | 64 | University Hospital, LinkoepingOTHER | 1 | Dec 4, 2023 | clinicaltrials |
| NCT02609425 | Intrathoracic Esophagogastric Anastomosis After Robot Assisted Minimally Invasive Esophagectomy Using STRATAFIX | completed | — | 30 | Henry Ford Health SystemOTHER | 1 | Nov 24, 2023 | clinicaltrials |
| NCT04187352 | A Study of CS1001 in Subjects With Esophageal Squamous Cell Carcinoma | completed | Phase 3 | 540 | CStone PharmaceuticalsINDUSTRY | 1 | Nov 24, 2023 | clinicaltrials |
| NCT03792347 | Preoperative Anti-PD-1 Antibody Combined With Chemoradiotherapy for Locally Advanced Squamous Cell Carcinoma of Esophagus(PALACE-1) | completed | Phase 1 | 20 | Hecheng Li M.D., Ph.DOTHER | 1 | Nov 22, 2023 | clinicaltrials |
| NCT05557955 | Identification of Breath Biomarkers in Esophageal Cancer(EC-CRT-005) | completed | — | 210 | Mian XIOTHER | 1 | Nov 18, 2023 | clinicaltrials |
| NCT01522768 | Afatinib and Paclitaxel in Patients With Advanced HER2-Positive Trastuzumab-Refractory Advanced Esophagogastric Cancer | completed | Phase 2 | 42 | Memorial Sloan Kettering Cancer CenterOTHER | 1 | Nov 1, 2023 | clinicaltrials |
| NCT03748134 | Sintilimab or Placebo With Chemotherapy in Esophageal Squamous Cell Carcinoma ( ORIENT-15 ) | completed | Phase 3 | 746 | Innovent Biologics (Suzhou) Co. Ltd.INDUSTRY | 7 | Oct 24, 2023 | clinicaltrials |
| NCT01401907 | Early Palliative Care in Advanced Lung and Gastrointestinal Malignancies | completed | N/A | 351 | Massachusetts General HospitalOTHER | 1 | Oct 19, 2023 | clinicaltrials |
| NCT05302011 | Neoadjuvant Pembrolizumab Plus Chemotherapy for Resectable Locally Advanced Esophageal Squamous Cell Carcinoma | completed | Phase 2 | 28 | Peking Union Medical College HospitalOTHER | 1 | Oct 10, 2023 | clinicaltrials |
Data updated 22 days agoSource updated Jun 27, 2024source: clinicaltrials