Clinical trial · Interventional
Capnographic Monitoring in Gastrointestinal Endoscopy for Elderly Patients
Capnographic Monitoring Decrease the Incidence of Hypoxia of the Elderly Patients Undergoing Gastrointestinal Endoscopy Procedure: a Randomized Multicenter Clinical Trial
NCT05030870CI-TRIAL-00075198CapnoGIcompletedN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Hypoxia is the most common adverse event in gastrointestinal endoscopes sedated with propofol and sufentanil, especially in elderly people. The aim of this randomized study was to determine whether intervention based on additional capnographic monitoring reduces the incidence of hypoxia in gastrointestinal endoscopes procedures for elderly patients.
Conditions
Conditions (6)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Colon Cancer | Malignant Colon Neoplasm | CURATED_EXACT | 0.92 |
| Colon Polyp | — | UNRESOLVED | — |
| Esophageal Cancer | Malignant Esophageal Neoplasm | CURATED_EXACT | 0.92 |
| Gastric Cancer | Malignant Gastric Neoplasm | CURATED_BROADER | 0.80 |
| Gastric Polyp | — | UNRESOLVED | — |
| Hypoxia | — | UNRESOLVED | — |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Capnography monitoring | Device | — | UNRESOLVED |
| Standard monitoring | Device | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- Capnographic monitoring group
- description
- In this group, in addition to the standard monitoring including observation, pulse oxygen saturation, non-invasive blood pressure, electrocardiogram in selected patients, the capnographic is also monitored. The capnographic data of the patients are available for additional noninvasive assessment of ventilation.
- interventionNames
- Device: Capnography monitoring
- Device: Standard monitoring
- type
- ACTIVE_COMPARATOR
- label
- Standard monitoring group
- description
- In this group, standard monitoring including observation, pulse oxygen saturation, non-invasive blood pressure, electrocardiogram in selected patients. Capnographic data are not visible by closing the CO2 sampling line till the endoscopy end.
- interventionNames
- Device: Standard monitoring
Primary outcomes (1)
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 65 Years
- Maximum age
- 79 Years
Show eligibility criteria text
Inclusion Criteria: * 65 ≤ Age \<80 * patients undergoing gastrointestinal endoscopes * patients signed informed consent form * ASA classification I-II Exclusion Criteria: * Coagulation disorders or a tendency of nose bleeding * An episode/exacerbation of congestive heart failure (CHF) that requires a change in medication, diet or hospitalization from any cause in the last 6 months * Severe aortic stenosis or mitral stenosis * Cardiac surgery involving thoracotomy (e.g., coronary artery bypass graft (CABG), valve replacement surgery) in the last 6 months * Acute myocardial infarction in the last 6 months * Acute arrhythmia (including any tachycardia - or bradycardia) with the fluid of hemodynamics instability * Diagnosed chronic obstructive pulmonary disease or current other acute or chronic lung disease requiring supplemental chronic or intermittent oxygen therapy) * Pre-existing bradycardia (heart rate \< 50 / min), or hypoxia (SaO2\< 90 % ) * Need supplemental oxygen because of pre-existing diseases * Emergency procedure or surgery * Multiple trauma * Upper respiratory tract infection * Allergy to propofol or tape and adhesives
References
Publications (1)
- DERIVEDLian Q, Chen S, Cheng X, Zhang J, Yu W, Zhou R, Su D. Capnographic monitoring reduces hypoxia incidence in older patients undergoing gastrointestinal endoscopy under propofol sedation: study protocol for a multicenter randomized controlled trial. Trials. 2023 Mar 15;24(1):192. doi: 10.1186/s13063-023-07208-0. PMID 36918924