Cancer
Malignant Esophageal Neoplasm
CI-CAN-00001127Explore in graph →
Top-level518 active trials6 approved drugs12 evidence items
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Cancer
CI-CAN-00001127Explore in graph →
Clinical trials
1,926 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
Computedformula ci-trial-intel-v1 · interventional studies · entity + NCIt descendants · hover a figure for its formulaCompare cancersTerminated studies (169)
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT07104838 | Non-intubated Versus Intubated Anesthesia in Thoracoscopic Esophagectomy for Esophageal Cancer | not yet recruiting | N/A | 500 | The First Affiliated Hospital of Guangzhou Medical UniversityOTHER | 0 | Sep 25, 2025 | clinicaltrials |
| NCT07180134 | Health Informatics and Resistance Exercise for Symptom Management and Quality of Life in Post-Esophagectomy Patients | not yet recruiting | N/A | 90 | Chang Gung Memorial HospitalOTHER | 0 | Sep 18, 2025 |
| clinicaltrials |
| NCT06796764 | COMBO Endoscopy Oropharyngeal Airway Reduces Hypoxia During Sedated Gastrointestinal Endoscopy in Obese Patients: A Multicenter, Randomized, Controlled Clinical Trial | recruiting | N/A | 580 | Zhejiang UniversityOTHER | 1 | Sep 10, 2025 | clinicaltrials |
| NCT03161535 | Effectiveness of a Rehabilitation Program in Improving Quality of Life in Patients With Esophageal Cancer | active not recruiting | N/A | 85 | Taipei Veterans General Hospital, TaiwanOTHER_GOV | 1 | Jul 28, 2025 | clinicaltrials |
| NCT07067359 | The Intensive Nutritional Support in Esophageal Cancer Undergoing Neoadjuvant Therapy(INSECNT) | not yet recruiting | N/A | 200 | Sichuan UniversityOTHER | 0 | Jul 16, 2025 | clinicaltrials |
| NCT07067450 | Adjuvant Immunotherapy for Esophageal Squamous Cell Carcinoma | not yet recruiting | N/A | 98 | Sichuan UniversityOTHER | 0 | Jul 16, 2025 | clinicaltrials |
| NCT06081647 | The Efficacy and Safety of the COMBO Endoscopy Oropharyngeal Airway in Gastrointestinal Endoscopy Procedure | recruiting | N/A | 1,200 | RenJi HospitalOTHER | 1 | Jun 25, 2025 | clinicaltrials |
| NCT07024849 | Developing an Ecological and Tailored Nutritional Intervention to Improve Quality of Life in Esophageal Cancer Survivors | recruiting | N/A | 30 | Samsung Medical CenterOTHER | 1 | Jun 17, 2025 | clinicaltrials |
| NCT07004634 | Comparison of Drainage Methods in Minimally Invasive Esophagectomy (DEMURE) | recruiting | N/A | 75 | Ruijin HospitalOTHER | 1 | Jun 10, 2025 | clinicaltrials |
| NCT06997302 | A Study on the Impact of Intelligent Nutrition Management on Clinical Outcomes in Chemotherapy Patients With Gastrointestinal Malignancies | active not recruiting | N/A | 150 | Tianjin Medical University Cancer Institute and HospitalOTHER | 1 | May 30, 2025 | clinicaltrials |
| NCT06986291 | Radiation-induced Toxicity of the Heart(CorTox) | not yet recruiting | N/A | 325 | Technische Universität DresdenOTHER | 1 | May 29, 2025 | clinicaltrials |
| NCT06876454 | Optimal Nutritional Palliation of Obstructed GEJ Cancer | not yet recruiting | N/A | 33 | London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph'sOTHER | 1 | May 25, 2025 | clinicaltrials |
| NCT06990178 | Adaptive Neoadjuvant Therapy for Esophageal Cancer | enrolling by invitation | N/A | 43 | Cancer Hospital Chinese Academy of Medical Science, Shenzhen CenterOTHER | 1 | May 25, 2025 | clinicaltrials |
| NCT06979986 | SLND Versus Non-Dissection Following ESD for T1a Stage Esophageal Squamous Cell Carcinoma | not yet recruiting | N/A | 102 | Fujian Cancer HospitalOTHER_GOV | 0 | May 20, 2025 | clinicaltrials |
| NCT06668454 | Chemoimmunotherapy Followed by Surgery for Oligometastatic Esophagogastric Cancer: (TORO Protocol)(TORO) | recruiting | N/A | 72 | University Health Network, TorontoOTHER | 1 | May 16, 2025 | clinicaltrials |
| NCT04734821 | Fluorescence Image Guided Foregut Surgery(FOREGUT) | recruiting | N/A | 60 | IHU StrasbourgOTHER | 1 | May 1, 2025 | clinicaltrials |
| NCT06926374 | Prospective Evaluation of Cornerstone Robotics Sentire Surgical System in Major Gastrointestinal and Urologic Surgery | recruiting | N/A | 90 | Chinese University of Hong KongOTHER | 1 | Apr 16, 2025 | clinicaltrials |
| NCT05706025 | Study to Evaluate EnteroTracker® as a Sampling Method to Screen for Barrett's Esophagus/Esophageal Cancer | enrolling by invitation | N/A | 60 | University of Colorado, DenverOTHER | 1 | Apr 6, 2025 | clinicaltrials |
| NCT06715501 | Efficacy and Safety of Cadonilimab and Chemoradiotherapy in Unresectable Locally Advanced Esophageal Squamous Cell Carcinoma | enrolling by invitation | N/A | 20 | First Affiliated Hospital of Ningbo UniversityNETWORK | 1 | Mar 25, 2025 | clinicaltrials |
| NCT06879483 | Thoraco-laparoscopic Partial Esophagogastrectomy for Management of Esophageal Cancer | not yet recruiting | N/A | 30 | Sohag UniversityOTHER | 1 | Mar 17, 2025 | clinicaltrials |
| NCT06863831 | A Multicenter Trial of YSQTG vs. Simulated Agents With Neoadjuvant Chemoradiotherapy or Chemoimmunotherapy for EC | enrolling by invitation | N/A | 536 | Cancer Institute and Hospital, Chinese Academy of Medical SciencesOTHER | 1 | Mar 7, 2025 | clinicaltrials |
| NCT06713421 | Effect of Premedication With Pronase on Mucosal Cleanliness During EGD | recruiting | N/A | 3,000 | Changhai HospitalOTHER | 1 | Feb 25, 2025 | clinicaltrials |
| NCT06306755 | Effectiveness of Risk-based Sequential Screening for Esophageal and Gastric Cancer(ERSS-EGC) | recruiting | N/A | 21,000 | Peking University Cancer Hospital & InstituteOTHER | 1 | Jan 24, 2025 | clinicaltrials |
| NCT06787807 | Proteomic Analysis of Patients Undergoing Bariatric Surgery | not yet recruiting | N/A | 103 | Universidade Federal de PernambucoOTHER | 1 | Jan 22, 2025 | clinicaltrials |
| NCT06762158 | NCRT Combined With Sequential Perioperative PD-1 Inhibitor for LAESCC | active not recruiting | N/A | 50 | RenJi HospitalOTHER | 1 | Jan 7, 2025 | clinicaltrials |
| NCT06756841 | Safety and Efficacy Study of Pulsed Electric Field (PEF) Therapy in Patients With Advanced or Unresectable Esophageal Squamous Cell Carcinoma | not yet recruiting | N/A | 10 | Energenx Medical LTD.INDUSTRY | 1 | Jan 3, 2025 | clinicaltrials |
| NCT06755866 | DCE-MRI Based on 4D Free Breathing for Predicting Preoperative Neoadjuvant Chemoradiotherapy for Esophageal Cancer | recruiting | N/A | 135 | Yunnan Cancer HospitalOTHER | 1 | Jan 1, 2025 | clinicaltrials |
| NCT06722300 | Clinical Study on the Impact of Eradication of Oral Porphyromonas Gingivalis on the Prognosis of Early Esophageal Cancer After ESD Surgery | active not recruiting | N/A | 856 | The First Affiliated Hospital of Henan University of Science and TechnologyOTHER | 1 | Dec 9, 2024 | clinicaltrials |
| NCT05370144 | A Study Involving Neoadjuvant Chemoradiotherapy with Hypofractionated Radiotherapy in Patients with Esophageal and Gastroesophageal Junction Adenocarcinoma | recruiting | N/A | 42 | AHS Cancer Control AlbertaOTHER | 1 | Nov 18, 2024 | clinicaltrials |
| NCT06649474 | Evaluation, in Humans, of the Correlation Between Hepatotoxicity, Neurotoxicity Induced by Oxaliplatin, and Blood Levels of HMGB1(HEPATOXALI) | recruiting | N/A | 100 | University Hospital, Clermont-FerrandOTHER | 1 | Oct 18, 2024 | clinicaltrials |
| NCT04584008 | Targeted Agent Evaluation in Digestive Cancers in China Based on Molecular Characteristics(VISIONARY) | active not recruiting | N/A | 600 | Peking UniversityOTHER | 1 | Oct 15, 2024 | clinicaltrials |
| NCT06632886 | AI-Assisted Non-Contrast CT for Multi-Cancer Screening | recruiting | N/A | 1,000,000 | Guo ShiWeiOTHER | 1 | Oct 9, 2024 | clinicaltrials |
| NCT06618742 | Focal Cryoballoon Ablation for Malignant Dysphagia(DYS-CBAS) | recruiting | N/A | 20 | Laura BoerOTHER | 1 | Oct 1, 2024 | clinicaltrials |
| NCT05953181 | Statistical Analysis Plan for the SANO-trial: Neoadjuvant Chemoradiotherapy Followed by Surgery Versus Active Surveillance for Oesophageal Cancer(SANO) | active not recruiting | N/A | 776 | Erasmus Medical CenterOTHER | 1 | Sep 19, 2024 | clinicaltrials |
| NCT06602843 | Neoadjuvant Chemoimmunotherapy Followed by Surgery and Postoperative Radioimmunotherapy | recruiting | N/A | 70 | Anhui Provincial HospitalOTHER_GOV | 1 | Sep 19, 2024 | clinicaltrials |
| NCT04498767 | Stereotactic Body Radiotherapy in Patients With Rare Oligometastatic Cancers (OligoRARE)(OligoRARE) | recruiting | N/A | 200 | European Organisation for Research and Treatment of Cancer - EORTCNETWORK | 7 | Aug 26, 2024 | clinicaltrials |
| NCT03306901 | Chemoradiotherapy Versus Esophagectomy After Endoscopic Resection for Superficial Esophageal Squamous Cell Carcinoma(ASSURE) | active not recruiting | N/A | 240 | Samsung Medical CenterOTHER | 1 | May 23, 2024 | clinicaltrials |
| NCT06418516 | Early Detection of Esophageal Squamous Cancer With the Capsule Sponge Device(ANGELA) | not yet recruiting | N/A | 340 | Centre of Postgraduate Medical EducationOTHER | 0 | May 17, 2024 | clinicaltrials |
| NCT06048926 | Carrelizumab Combined With Concurrent Radiotherapy and Chemotherapy for Unresectable Esophageal Squamous Cell Carcinoma | enrolling by invitation | N/A | 30 | The First Affiliated Hospital with Nanjing Medical UniversityOTHER | 1 | Sep 21, 2023 | clinicaltrials |
| NCT06037902 | CPAP for Esophageal Cancer With Radiotherapy(TROS-7) | recruiting | N/A | 44 | Sheba Medical CenterOTHER_GOV | 1 | Sep 14, 2023 | clinicaltrials |
| NCT05954117 | Chemotherapy in the Context of Esophageal and Gastroesophageal Junction Cancer Cachexia(CHIFMEOE) | not yet recruiting | N/A | 60 | University Hospital, Clermont-FerrandOTHER | 1 | Jul 20, 2023 | clinicaltrials |
| NCT05951127 | Additional Consolidative Esophagectomy for the Patients With Oligometastatic Resectable ESCC(LEO) | active not recruiting | N/A | 141 | Cancer Institute and Hospital, Chinese Academy of Medical SciencesOTHER | 1 | Jul 18, 2023 | clinicaltrials |
| NCT05775419 | Comparison of Chemoradiotherapy and Chemoradiotherapy Combined With Consolidation Chemotherapy for ESCC | recruiting | N/A | 1,216 | The First Affiliated Hospital with Nanjing Medical UniversityOTHER | 1 | Mar 20, 2023 | clinicaltrials |
| NCT04652180 | Robot-assisted Thoracic Approach Versus Open Transthoracic Esophagectomy .(CIR·ROB) | recruiting | N/A | 108 | Hospital Universitari de BellvitgeOTHER | 1 | Mar 1, 2023 | clinicaltrials |
| NCT04688801 | Ajuvant Chemotherapy and Immunotherapy in Patients With Esophageal, Esophageal- Gastric Junction Cancer | recruiting | N/A | 200 | The Second Hospital of Shandong UniversityOTHER | 1 | Nov 16, 2022 | clinicaltrials |
| NCT05420480 | Two-field Versus Three-field Lymph Node Dissection in ESCC After Neoadjuvant Therapy | not yet recruiting | N/A | 323 | Shanghai Zhongshan HospitalOTHER | 1 | Jun 21, 2022 | clinicaltrials |
| NCT04306458 | RAMIE Versus MIE for Resectable Esophageal Cancer, a Randomized Controlled Trial (ROBOT-2 Trial).(ROBOT-2) | recruiting | N/A | 218 | University Medical Center MainzOTHER | 1 | May 17, 2022 | clinicaltrials |
| NCT05105945 | Clinical Study on the Efficacy of Single-port Inflatable Mediastinoscopy Combined With Laparoscopic-assisted Small Incision Surgery and Thoracoscopy Combined With Laparoscopic Surgery for Radical Esophagectomy | not yet recruiting | N/A | 1,164 | Fifth Affiliated Hospital, Sun Yat-Sen UniversityOTHER | 1 | Nov 3, 2021 | clinicaltrials |
| NCT04519905 | Phase III Study of Concurrent Radiotherapy in Elderly Patients With Esophageal Squamous Cell Carcinoma (ESO-Shanghai 15) | recruiting | N/A | 320 | Fudan UniversityOTHER | 1 | Nov 2, 2021 | clinicaltrials |
| NCT03787056 | Predictive Value of Progastrin Titer at Diagnosis and of Progastrin Kinetics During Treatment in Cancer Patients(ONCOPRO) | recruiting | N/A | 410 | Hospices Civils de LyonOTHER | 1 | Jul 16, 2021 | clinicaltrials |
Data updated 22 days agoSource updated Sep 25, 2025source: clinicaltrials