Cancer Family
Malignant Digestive System Neoplasm
CI-CAN-00000229Explore in graph →
4,262 active trials43 approved drugs556 evidence items
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Cancer Family
CI-CAN-00000229Explore in graph →
Clinical trials
19,101 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
Computedformula ci-trial-intel-v1 · interventional studies · entity + NCIt descendants · hover a figure for its formulaCompare cancersTerminated studies (2,000)
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT06347198 | Oral Inulin in Combination With Fruquintinib Plus Sintilimab as Third- or Further-line Treatment in Metastatic Colorectal Cancer | unknown | Early Phase 1 | 30 | Union Hospital, Tongji Medical College, Huazhong University of Science and TechnologyOTHER | 1 | Apr 4, 2024 | clinicaltrials |
| NCT06224738 | Human HER2-targeted Macrophages Therapy for HER2-positive Advanced Gastric Cancer With Peritoneal Metastases | unknown | Early Phase 1 | 9 | First People's Hospital of HangzhouOTHER |
| 1 |
| Jan 25, 2024 |
| clinicaltrials |
| NCT05070156 | B010-A Injection for Treating Patients With GPC3 Positive Advanced Hepatocellular Carcinoma | unknown | Early Phase 1 | 3 | Tongji UniversityOTHER | 1 | Dec 15, 2023 | clinicaltrials |
| NCT06098898 | Safety and Efficacy of NK510 to Treat Gastric Cancer | unknown | Early Phase 1 | 9 | Base Therapeutics (Shanghai) Co., Ltd.INDUSTRY | 1 | Oct 25, 2023 | clinicaltrials |
| NCT06054984 | TCR-T Cells in the Treatment of Advanced Pancreatic Cancer(GB3010-02) | unknown | Early Phase 1 | 18 | Ruijin HospitalOTHER | 1 | Oct 13, 2023 | clinicaltrials |
| NCT05648955 | Effect of an Oral Nutritional Supplement on Muscle Mass During Anticancer Treatment(ALLIES) | unknown | Early Phase 1 | 118 | Nutricia ResearchINDUSTRY | 1 | Jul 28, 2023 | clinicaltrials |
| NCT05937919 | 68Ga-PMD22 PET/CT Examination Targeting CLDN18.2 | unknown | Early Phase 1 | 10 | Peking Union Medical College HospitalOTHER | 1 | Jul 10, 2023 | clinicaltrials |
| NCT05891028 | 64Cu/68Ga Labelled EB-ss-CPT PET/CT Scan in Colorectal Cancer | unknown | Early Phase 1 | 10 | Peking Union Medical College HospitalOTHER | 1 | Jun 8, 2023 | clinicaltrials |
| NCT05886075 | A Clinical Study on Oncolytic Virus Injection (R130) for the Treatment of Relapsed/Refractory Advanced Solid Tumors | unknown | Early Phase 1 | 24 | Shanghai Yunying Medical TechnologyINDUSTRY | 1 | Jun 2, 2023 | clinicaltrials |
| NCT05875753 | 68Ga-FAPI-FS PET/CT and PET/MR in Pancreatic Cancer | unknown | Early Phase 1 | 50 | Peking Union Medical College HospitalOTHER | 1 | May 25, 2023 | clinicaltrials |
| NCT05860374 | A Clinical Study on Oncolytic Virus Injection (R130) for the Treatment of Advanced Solid Tumors | unknown | Early Phase 1 | 20 | Shanghai Yunying Medical TechnologyINDUSTRY | 1 | May 16, 2023 | clinicaltrials |
| NCT05830240 | A Clinical Study on Oncolytic Virus Injection (R130 OV) for the Treatment of Relapsed/Refractory Head and Neck Cancer | unknown | Early Phase 1 | 9 | Shanghai Yunying Medical TechnologyINDUSTRY | 1 | Apr 26, 2023 | clinicaltrials |
| NCT05093920 | Role of DEB-TACE Versus c-TACE in Treatment of HCC | unknown | Early Phase 1 | 30 | Sohag UniversityOTHER | 1 | Apr 12, 2023 | clinicaltrials |
| NCT05759741 | Alterations of Gut Microbiome, Function, and Its Intervention After Defunctioning Ileostomy | unknown | Early Phase 1 | 64 | Huashan HospitalOTHER | 1 | Mar 14, 2023 | clinicaltrials |
| NCT05583201 | NKG2D/CLDN18.2 CAR-T(KD-496) in the Treatment of Advanced NKG2DL+/CLDN18.2+ Solid Tumors | unknown | Early Phase 1 | 18 | jianming xuOTHER | 1 | Feb 8, 2023 | clinicaltrials |
| NCT03099564 | Pembrolizumab Plus Y90 Radioembolization in HCC Subjects | unknown | Early Phase 1 | 30 | Ashwin SomasundaramOTHER | 1 | Feb 6, 2023 | clinicaltrials |
| NCT05131698 | Clinical Study of the Efficacy and Safety of Transhepatic Arterial Chemoembolization Combined With Tislelizumab and Lenvatinib in Patients With Advanced Unresectable Hepatocellular Carcinoma | unknown | Early Phase 1 | 31 | Cancer Hospital of Guangxi Medical UniversityOTHER | 1 | Jan 26, 2023 | clinicaltrials |
| NCT04974281 | PD-1 Antibody and Lenvatinib Plus TACE on Downstaging BCLC B/C HCC | unknown | Early Phase 1 | 50 | Fudan UniversityOTHER | 1 | Aug 18, 2022 | clinicaltrials |
| NCT05438797 | The Safety and Efficacy of Specific TIL-TCM Cells for Advanced Relapse-refractory or Metastatic Pancreatic Cancer | unknown | Early Phase 1 | 3 | Sizhen WangOTHER | 1 | Jun 30, 2022 | clinicaltrials |
| NCT05382377 | NKG2D CAR-T(KD-025) in the Treatment of Advanced NKG2DL+ Solid Tumors | unknown | Early Phase 1 | 18 | jianming xuOTHER | 1 | May 19, 2022 | clinicaltrials |
| NCT05287165 | Clinical Trial to Evaluate the Safety and Efficacy of IM96 CAR-T Cells Therapy in Patients With Advanced Digestive System Neoplasms | unknown | Early Phase 1 | 19 | Beijing Immunochina Medical Science & Technology Co., Ltd.INDUSTRY | 1 | Mar 18, 2022 | clinicaltrials |
| NCT05275062 | Clinical Trial to Evaluate the Safety and Efficacy of IM92 CAR-T Cells Therapy in Patients With Advanced Gastric or Pancreatic Adenocarcinoma | unknown | Early Phase 1 | 6 | Beijing Immunochina Medical Science & Technology Co., Ltd.INDUSTRY | 1 | Mar 11, 2022 | clinicaltrials |
| NCT05248048 | NKG2D CAR-T Cells to Treat Patients With Previously Treated Liver Metastatic Colorectal Cancer | unknown | Early Phase 1 | 9 | The Third Affiliated Hospital of Guangzhou Medical UniversityOTHER | 1 | Feb 21, 2022 | clinicaltrials |
| NCT02786329 | Anesthesia and Postoperative Outcome in Colorectal Cancer Patients | unknown | Early Phase 1 | 450 | Institutul Regional de Gastroenterologie & Hepatologie Prof. dr. Octavian FodorOTHER | 1 | Jan 20, 2022 | clinicaltrials |
| NCT05154812 | Yang Yin Fu Zheng Jie Du Therapy in HBV Associated Hepatocellular Carcinoma Based on the Platelet Count/Splenic Length-Diameter Ratio | unknown | Early Phase 1 | 108 | Beijing Ditan HospitalOTHER | 1 | Dec 13, 2021 | clinicaltrials |
| NCT05152498 | Fu Zheng Jie Du Hua Yu Principle For Treatment Of Severe HBV Related Hepatocellular Carcinoma (FZJDHYPFTOSHBVHCC) | unknown | Early Phase 1 | 142 | Beijing Ditan HospitalOTHER | 1 | Dec 9, 2021 | clinicaltrials |
| NCT05088733 | Yang Yin Fu Zheng Jie Du Therapy in HBV Related Hepatocellular Carcinoma Induced Anemia (YYFZJDTIHBVRHCIA) | unknown | Early Phase 1 | 120 | Beijing Ditan HospitalOTHER | 1 | Nov 19, 2021 | clinicaltrials |
| NCT02749513 | Itraconazole as a Targeted Therapy for Inhibiting Hedgehog Pathway Signaling in Esophageal Cancer Patients | unknown | Early Phase 1 | 18 | Dallas VA Medical CenterFED | 1 | Nov 4, 2021 | clinicaltrials |
| NCT05105815 | Safety and Efficacy of Autoimmune Cell Therapy for Patients With Hepatocellular Carcinoma | unknown | Early Phase 1 | 23 | Huashan HospitalOTHER | 1 | Nov 3, 2021 | clinicaltrials |
| NCT05100446 | Comparison Between High-dose Amoxicillin Dual Therapy and Pylera Quadruple Therapy in the Treatment of Helicobacter Pylori Infection | unknown | Early Phase 1 | 100 | Unidade Local de Saúde do Alto Ave, EPEOTHER | 1 | Oct 29, 2021 | clinicaltrials |
| NCT05007587 | Lenvatinib Plus HAIC of Modified FOLFOX Regime vs Lenvatinib Plus HAIC of ROX Regime in Patients With Advanced HCC | unknown | Early Phase 1 | 60 | Zhejiang Cancer HospitalOTHER | 1 | Aug 16, 2021 | clinicaltrials |
| NCT04966143 | Clinical Study of LY011 in the Treatment of Advanced Pancreatic Cancer | unknown | Early Phase 1 | 30 | Shanghai Longyao Biotechnology Inc., Ltd.OTHER | 1 | Jul 19, 2021 | clinicaltrials |
| NCT04951141 | Clinical Study of Intratumoral Injection of CAR-T Cells in the Treatment of Advanced Liver Tumors | unknown | Early Phase 1 | 10 | Beijing Immunochina Medical Science & Technology Co., Ltd.INDUSTRY | 1 | Jul 6, 2021 | clinicaltrials |
| NCT04864821 | Clinical Study of CD276 Targeted Autologous Chimeric Antigen Receptor T Cell Infusion in Patients With CD276 Positive Advanced Solid Tumor | unknown | Early Phase 1 | 24 | PersonGen BioTherapeutics (Suzhou) Co., Ltd.INDUSTRY | 0 | May 6, 2021 | clinicaltrials |
| NCT04518774 | Allogeneic "Gammadelta T Cells (γδ T Cells)" Cell Immunotherapy in Phase 1 Hepatocellular Carcinoma Clinical Trial | unknown | Early Phase 1 | 8 | Beijing 302 HospitalOTHER | 1 | Aug 19, 2020 | clinicaltrials |
| NCT04513431 | A Clinical Research of CAR T Cells Targeting CEA Positive Colorectal Cancer (CRC)(CRC) | unknown | Early Phase 1 | 18 | Ruijin HospitalOTHER | 0 | Aug 14, 2020 | clinicaltrials |
| NCT04503980 | αPD1-MSLN-CAR T Cells for the Treatment of MSLN-positive Advanced Solid Tumors | unknown | Early Phase 1 | 10 | Shanghai Cell Therapy Group Co.,LtdINDUSTRY | 1 | Aug 7, 2020 | clinicaltrials |
| NCT04251403 | Novel Approach to Surveillance of Gastric Lesions | unknown | Early Phase 1 | 10 | New York Presbyterian HospitalOTHER | 0 | Jan 31, 2020 | clinicaltrials |
| NCT04113096 | Dibenzyl Trisulphide (GUINEAHEN WEED) for Stage IV Cancer | unknown | Early Phase 1 | 104 | The University of The West IndiesOTHER | 1 | Oct 8, 2019 | clinicaltrials |
| NCT03940001 | A Study of Sintilimab Plus Chemoradiation Before Surgery for Esophageal Cancer | unknown | Early Phase 1 | 20 | Zhejiang Cancer HospitalOTHER | 1 | Sep 9, 2019 | clinicaltrials |
| NCT03965546 | ET 140202 -T Cell Combined With TAE or Sorafenib in the Treatment of Liver Cancer | unknown | Early Phase 1 | 27 | First Affiliated Hospital Xi'an Jiaotong UniversityOTHER | 1 | Aug 8, 2019 | clinicaltrials |
| NCT04048317 | Effectiveness of Drug Eluting TACE in Primary HCC | unknown | Early Phase 1 | 75 | Assiut UniversityOTHER | 0 | Aug 7, 2019 | clinicaltrials |
| NCT03822130 | Intra-arterial Infusion Chemotherapy Combined With Sodium Bicarbonate for Unresectable Gastric Cancer | unknown | Early Phase 1 | 150 | Second Affiliated Hospital, Zhejiang University, School of MedicineOTHER | 1 | Feb 20, 2019 | clinicaltrials |
| NCT03672305 | Clinical Study on the Efficacy and Safety of c-Met/PD-L1 CAR-T Cell Injection in the Treatment of HCC | unknown | Early Phase 1 | 50 | The Second Hospital of Nanjing Medical UniversityOTHER | 0 | Sep 18, 2018 | clinicaltrials |
| NCT03497819 | Autologous CARTmeso/19 Against Pancreatic Cancer | unknown | Early Phase 1 | 10 | First Affiliated Hospital of Wenzhou Medical UniversityOTHER | 1 | Apr 13, 2018 | clinicaltrials |
| NCT03245554 | Clinical Research on Teratment of Gastrointestinal Cancer in the Preoperative by Propranolol | unknown | Early Phase 1 | 80 | Central South UniversityOTHER | 1 | Apr 9, 2018 | clinicaltrials |
| NCT03385148 | The Clinical Application of 68Ga Labeled ssDNA Aptamer Sgc8 in Healthy Volunteers and Colorectal Patients | unknown | Early Phase 1 | 70 | Xijing HospitalOTHER | 1 | Dec 28, 2017 | clinicaltrials |
| NCT03267173 | Evaluate the Safety and Efficacy of CAR-T in the Treatment of Pancreatic Cancer. | unknown | Early Phase 1 | 10 | First Affiliated Hospital of Harbin Medical UniversityOTHER | 1 | Aug 30, 2017 | clinicaltrials |
| NCT03070613 | Investigating the Use of Fluorescent Lectins to Identify Dysplasia and Cancer During Endoscopy and Surgery | unknown | Early Phase 1 | 50 | University of OxfordOTHER | 1 | Jul 18, 2017 | clinicaltrials |
| NCT03214939 | Autologous Antigen-activated Dendritic Cells in the Treatment of Patients With Colorectal Cancer | unknown | Early Phase 1 | 30 | Research Institute of Fundamental and Clinical ImmunologyOTHER_GOV | 1 | Jul 12, 2017 | clinicaltrials |
Data updated 22 days agoSource updated Apr 4, 2024source: clinicaltrials