Cancer Family
Malignant Digestive System Neoplasm
CI-CAN-00000229Explore in graph →
4,262 active trials43 approved drugs556 evidence items
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Cancer Family
CI-CAN-00000229Explore in graph →
Clinical trials
19,108 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
Computedformula ci-trial-intel-v1 · interventional studies · entity + NCIt descendants · hover a figure for its formulaCompare cancersTerminated studies (2,001)
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT07818070 | A Trial of ONO-4578 Versus Placebo in Combination With Nivolumab and Chemotherapy in Participants With Gastric Cancer, Esophagogastric Junction Cancer, or Esophageal Adenocarcinoma | not yet recruiting | Phase 3 | 600 | Ono Pharmaceutical Co., Ltd.INDUSTRY | 0 | Sep 14, 2026 | clinicaltrials |
| NCT07819019 | A Phase II Study of Irinotecan Liposome Plus Fruquintinib and Sintilimab in Second-Line PD-L1-Positive Advanced Gastric Cancer | not yet recruiting | Phase 2 | 20 | Cancer Hospital Chinese Academy of Medical Science, Shenzhen CenterOTHER |
| 0 |
| Sep 14, 2026 |
| clinicaltrials |
| NCT01585805 | Gemcitabine Hydrochloride and Cisplatin With or Without Veliparib or Veliparib Alone in Treating Patients With Locally Advanced or Metastatic Pancreatic Cancer | active not recruiting | Phase 2 | 83 | National Cancer Institute (NCI)NIH | 3 | Sep 11, 2026 | clinicaltrials |
| NCT02134925 | Vaccine Therapy in Treating Patients With Newly Diagnosed Advanced Colon Polyps | active not recruiting | Phase 2 | 110 | National Cancer Institute (NCI)NIH | 2 | Sep 11, 2026 | clinicaltrials |
| NCT02521285 | Aspirin in Preventing Disease Recurrence in Patients With Barrett Esophagus After Successful Elimination by Radiofrequency Ablation | active not recruiting | Phase 2 | 21 | National Cancer Institute (NCI)NIH | 2 | Sep 11, 2026 | clinicaltrials |
| NCT02772003 | DNA Vaccine Therapy in Treating Patients With Chronic Hepatitis C Virus Infection | active not recruiting | Phase 1 | 33 | National Cancer Institute (NCI)NIH | 2 | Sep 11, 2026 | clinicaltrials |
| NCT03878550 | Case-Control Study of the Glycotest™ HCC Panel vs AFP for the Detection of Early-stage Hepatocellular Carcinoma | active not recruiting | — | 766 | Glycotest, Inc.INDUSTRY | 2 | Sep 11, 2026 | clinicaltrials |
| NCT04140500 | Dose Escalation Study of a PD1-LAG3 Bispecific Antibody in Patients With Advanced and/or Metastatic Solid Tumors | active not recruiting | Phase 1 / Phase 2 | 170 | Hoffmann-La RocheINDUSTRY | 9 | Sep 11, 2026 | clinicaltrials |
| NCT04381130 | A Phase I/IIa Study of EF-009 in Patients With Pancreatic Cancer | not yet recruiting | Phase 1 / Phase 2 | 30 | Everfront Biotech Co., Ltd.INDUSTRY | 0 | Sep 11, 2026 | clinicaltrials |
| NCT04444921 | EA2176: Phase 3 Clinical Trial of Carboplatin and Paclitaxel +/- Nivolumab in Metastatic Anal Cancer Patients | active not recruiting | Phase 3 | 205 | National Cancer Institute (NCI)NIH | 1 | Sep 11, 2026 | clinicaltrials |
| NCT04665947 | First-in-human Study of the Theranostic Pair [68Ga]Ga DOTA-5G and [177Lu]Lu DOTA-ABM-5G in Pancreatic Cancer | active not recruiting | Early Phase 1 | 30 | University of California, DavisOTHER | 1 | Sep 11, 2026 | clinicaltrials |
| NCT04739696 | Developing a Virtual Stress Management Intervention for Spousal/Partnered Caregivers of Solid Tumor Cancer Patients.(eCare) | active not recruiting | N/A | 538 | University of Colorado, DenverOTHER | 1 | Sep 11, 2026 | clinicaltrials |
| NCT04817826 | TremelImumab aNd Durvalumab For the Non-operatIve Management (NOM) of MSI-high Resectable GC/GEJC.(INFINITY) | active not recruiting | Phase 2 | 31 | Gruppo Oncologico del Nord-OvestOTHER | 1 | Sep 11, 2026 | clinicaltrials |
| NCT04820179 | Atezolizumab + Cabozantinib in Patients w/ Metastatic, Refractory Pancreatic Cancer | active not recruiting | Phase 2 | 32 | University of ArizonaOTHER | 1 | Sep 11, 2026 | clinicaltrials |
| NCT04905082 | HOPE-Genomics Intervention for the Improvement of Cancer Patient Knowledge of Genomics | active not recruiting | N/A | 465 | City of Hope Medical CenterOTHER | 1 | Sep 11, 2026 | clinicaltrials |
| NCT04929223 | A Study Evaluating the Safety and Efficacy of Targeted Therapies in Subpopulations of Patients With Metastatic Colorectal Cancer (INTRINSIC) | recruiting | Phase 1 | 542 | Hoffmann-La RocheINDUSTRY | 11 | Sep 11, 2026 | clinicaltrials |
| NCT05077800 | FOLFIRINOX + Elraglusib + Losartan In Pancreatic Cancer | active not recruiting | Phase 2 | 70 | Colin D. Weekes, M.D., PhDOTHER | 1 | Sep 11, 2026 | clinicaltrials |
| NCT05123482 | A Phase I/IIa Study of AZD8205 Given Alone or Combined, in Participants With Advanced/Metastatic Solid Malignancies | recruiting | Phase 1 / Phase 2 | 460 | AstraZenecaINDUSTRY | 15 | Sep 11, 2026 | clinicaltrials |
| NCT05365581 | A Study of ASP2138 Given by Itself or Given With Other Cancer Treatments in Adults With Stomach Cancer, Gastroesophageal Junction Cancer, or Pancreatic Cancer | recruiting | Phase 1 | 398 | Astellas Pharma Global Development, Inc.INDUSTRY | 8 | Sep 11, 2026 | clinicaltrials |
| NCT05630794 | Testing for Safety and Colorectal Cancer Preventive Effects of ONC201 | recruiting | Phase 1 | 36 | National Cancer Institute (NCI)NIH | 1 | Sep 11, 2026 | clinicaltrials |
| NCT05753748 | Surveillance vs. Endoscopic Therapy for Barrett's Esophagus With Low-grade Dysplasia(SURVENT) | recruiting | N/A | 680 | University of Colorado, DenverOTHER | 1 | Sep 11, 2026 | clinicaltrials |
| NCT05845450 | Pre-operative Targeted Treatments in Molecularly Selected Resectable Colorectal Cancer (UNICORN) | recruiting | Phase 2 | 197 | Gruppo Oncologico del Nord-OvestOTHER | 1 | Sep 11, 2026 | clinicaltrials |
| NCT05850130 | Acupuncture for Oxaliplatin-induced Peripheral Neuropathy in Gastro-intestinal Cancer Patients(ACUPOX) | recruiting | N/A | 182 | GERCOR - Multidisciplinary Oncology Cooperative GroupOTHER | 1 | Sep 11, 2026 | clinicaltrials |
| NCT05935384 | SIBYL: obServation of Therapy Response With lIquid BiopsY evaLuation | recruiting | — | 470 | Guardant Health, Inc.INDUSTRY | 1 | Sep 11, 2026 | clinicaltrials |
| NCT06141031 | Radiotherapy in Combination With TTI-101 in Borderline Resectable and Locally Advanced Pancreatic Ductal Adenocarcinoma | recruiting | Phase 1 | 24 | Washington University School of MedicineOTHER | 1 | Sep 11, 2026 | clinicaltrials |
| NCT06202183 | Exercise for Gut Microbiome in Patients With Young-Onset Colorectal Cancer Undergoing Chemotherapy: The COURAGE Trial | recruiting | N/A | 84 | Dana-Farber Cancer InstituteOTHER | 1 | Sep 11, 2026 | clinicaltrials |
| NCT06309485 | Phase 2 Study of WGI-0301 for Advanced HCC | recruiting | Phase 2 | 60 | Zhejiang Haichang Biotech Co., Ltd.INDUSTRY | 2 | Sep 11, 2026 | clinicaltrials |
| NCT06651580 | Biospecimen Collection to Identify Gene Mutations for High Risk Pancreatic Cancer in Pediatric Patients, INSPPIRE 2 Study | recruiting | — | 1,600 | M.D. Anderson Cancer CenterOTHER | 4 | Sep 11, 2026 | clinicaltrials |
| NCT06657222 | First in Human Study of TUB-030 in Patients With Advanced Solid Tumors | recruiting | Phase 1 / Phase 2 | 250 | Tubulis GmbHINDUSTRY | 5 | Sep 11, 2026 | clinicaltrials |
| NCT06764875 | A Phase Ⅲ Study of Rilvegostomig in Combination With Fluoropyrimidine and Trastuzumab Deruxtecan as the First-line Treatment for HER2-positive Gastric Cancer | recruiting | Phase 3 | 840 | AstraZenecaINDUSTRY | 28 | Sep 11, 2026 | clinicaltrials |
| NCT07081360 | Neoadjuvant vs Upfront Surgery for Resectable Pancreatic Cancer and Periampullary Cancer | recruiting | Phase 3 | 262 | Minia UniversityOTHER | 1 | Sep 11, 2026 | clinicaltrials |
| NCT07132541 | Saleh's Technique for Pancreaticojejunostomy (Pancreatic Parenchymal Injection of N-butyl-2-cyanoacrylate)(NBCA) | recruiting | Phase 1 | 30 | Minia UniversityOTHER | 1 | Sep 11, 2026 | clinicaltrials |
| NCT07148830 | Mesopancreatic Excision for Pancreatic Duct Adenocarcinoma.(TMpE) | recruiting | N/A | 100 | Minia UniversityOTHER | 1 | Sep 11, 2026 | clinicaltrials |
| NCT07333053 | Clinical Efficacy of Transarterial Infusion Chemotherapy for Unresectable Colorectal Cancer | recruiting | N/A | 50 | Guang'anmen Hospital of China Academy of Chinese Medical SciencesOTHER | 1 | Sep 11, 2026 | clinicaltrials |
| NCT07381764 | ROMANCE: "Irinotecan Plus Cetuximab Rechallenge Versus Trifluridine/Tipiracil Plus Bevacizumab in Molecularly Selected Metastatic Colorectal Cancer"(ROMANCE - GOIM) | recruiting | Phase 2 | 150 | Gruppo Oncologico Italia MeridionaleOTHER | 1 | Sep 11, 2026 | clinicaltrials |
| NCT07673887 | A Study of ASP2138 Together With Chemotherapy and Pembrolizumab in Adults With Gastric Cancer | recruiting | Phase 3 | 570 | Astellas Pharma Global Development, Inc.INDUSTRY | 3 | Sep 11, 2026 | clinicaltrials |
| NCT07714538 | Breath Research Narrow Validation for Gastrointestinal Cancer Detection(BRAVE) | recruiting | — | 1,000 | Imperial College LondonOTHER | 1 | Sep 11, 2026 | clinicaltrials |
| NCT07786493 | HDR Endorectal Brachytherapy With 3D-Printed Guidance and Local Shielding for Rectal Cancer Organ Preservation(NOM-HDR-W) | recruiting | N/A | 50 | Tianjin Medical University Cancer Institute and HospitalOTHER | 1 | Sep 11, 2026 | clinicaltrials |
| NCT07799740 | Examination of Rectal Blood Supply During Rectal Cancer Surgery Using Laser Speckle Contrast Imaging(LIRA) | not yet recruiting | N/A | 100 | University of AarhusOTHER | 1 | Sep 11, 2026 | clinicaltrials |
| NCT07814586 | Prognostic Evaluation and Systematic Re-Assessment of Cholangiocarcinoma Therapy(Re-ACT) | not yet recruiting | — | 900 | Karolinska University HospitalOTHER | 0 | Sep 11, 2026 | clinicaltrials |
| NCT07814859 | Retlirafusp Alfa Combined With Famitinib, Nab-Paclitaxel and Gemcitabine for First-Line Treatment of Patients With Unresectable Pancreatic Cancer | not yet recruiting | Phase 2 | 88 | The First Affiliated Hospital of Zhengzhou UniversityOTHER | 1 | Sep 11, 2026 | clinicaltrials |
| NCT07815054 | Efficacy Evaluation of Microwave Ablation Assisted by Diaphragm Hydrodissection for Hepatocellular Carcinoma and Comparative Analysis With Surgical | not yet recruiting | — | 200 | The First Hospital of Jilin UniversityOTHER | 0 | Sep 11, 2026 | clinicaltrials |
| NCT07815093 | Multimodal Artificial Intelligence for Non-Invasive Colorectal Cancer Screening Based on Holographic Biology | not yet recruiting | — | 11,000 | Xiuli ZuoOTHER | 0 | Sep 11, 2026 | clinicaltrials |
| NCT07816263 | Guaraná Supplementation for Cancer-Related Fatigue(GUARANA-CRF) | recruiting | — | 60 | Centro de Tratamiento e Investigación sobre Cáncer, Luis Carlos Sarmiento AnguloOTHER | 1 | Sep 11, 2026 | clinicaltrials |
| NCT01142388 | Paclitaxel With or Without Cixutumumab as Second-Line Therapy in Treating Patients With Metastatic Esophageal Cancer or Gastroesophageal Junction Cancer | active not recruiting | Phase 2 | 94 | National Cancer Institute (NCI)NIH | 1 | Sep 10, 2026 | clinicaltrials |
| NCT03233711 | Nivolumab After Combined Modality Therapy in Treating Patients With High Risk Stage II-IIIB Anal Cancer | active not recruiting | Phase 3 | 344 | National Cancer Institute (NCI)NIH | 2 | Sep 10, 2026 | clinicaltrials |
| NCT04514497 | Testing the Addition of an Anti-cancer Drug, BAY 1895344, to Usual Chemotherapy for Advanced Stage Solid Tumors, With a Specific Focus on Patients With Small Cell Lung Cancer, Poorly Differentiated Neuroendocrine Cancer, and Pancreatic Cancer | active not recruiting | Phase 1 | 29 | National Cancer Institute (NCI)NIH | 1 | Sep 10, 2026 | clinicaltrials |
| NCT04674267 | Resilience and Equity in Aging, Cancer, and Health (REACH)(REACH) | recruiting | N/A | 147 | Dana-Farber Cancer InstituteOTHER | 1 | Sep 10, 2026 | clinicaltrials |
| NCT04864054 | GPC3-Targeted T-Cell Therapy (ECT204) in Adults With Advanced HCC(ARYA-3) | recruiting | Phase 1 / Phase 2 | 60 | Eureka Therapeutics Inc.INDUSTRY | 2 | Sep 10, 2026 | clinicaltrials |
Data updated 17 days agoSource updated Sep 14, 2026source: clinicaltrials