Cancer Family
Malignant Digestive System Neoplasm
CI-CAN-00000229Explore in graph →
4,262 active trials43 approved drugs556 evidence items
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Cancer Family
CI-CAN-00000229Explore in graph →
Clinical trials
19,108 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
Computedformula ci-trial-intel-v1 · interventional studies · entity + NCIt descendants · hover a figure for its formulaCompare cancersTerminated studies (2,001)
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT05776381 | The Impact of a Patient Decision Aid on Treatment Choices for Patients With an Unexpected Malignant Colorectal Polyp | not yet recruiting | Phase 2 | 110 | Vejle HospitalOTHER | 0 | Apr 30, 2026 | clinicaltrials |
| NCT07365124 | MRinRT: Swansea University and SWWCC Collaboration Study.(MRinRT) | not yet recruiting | — | 165 | Swansea Bay University Health BoardOTHER | 1 | Apr 30, 2026 |
| clinicaltrials |
| NCT07499921 | Clinical and BIOgical Analyses of RECtal Tumors(BIOREC) | not yet recruiting | N/A | 300 | Centre Leon BerardOTHER | 1 | Apr 30, 2026 | clinicaltrials |
| NCT07558200 | Phase Ia/Ib Study of FXB0871 Monotherapy in Locally Advanced/Metastatic Solid Tumors | not yet recruiting | Phase 1 | 138 | Shanghai Fosun Pharmaceutical Industrial Development Co. Ltd.INDUSTRY | 1 | Apr 30, 2026 | clinicaltrials |
| NCT07555587 | Safety and Efficacy of NRT6008 Administered in Combination With Chemotherapy in Patients With Unresectable Locally Advanced Pancreatic Carcinoma (LAPC) | not yet recruiting | Phase 1 | 10 | NRT MedTech Australia Pty LtdINDUSTRY | 1 | Apr 29, 2026 | clinicaltrials |
| NCT07555600 | Enumeration and Functional Analysis of Circulating Tumor Cells for Homologous Recombination: a Prospective Single-center Study on Advanced/Metastatic Solid Tumors(E-FACTOR) | not yet recruiting | N/A | 300 | Centre Leon BerardOTHER | 0 | Apr 29, 2026 | clinicaltrials |
| NCT07556835 | Outcomes After Liver and Biliary Resection at a High-Volume Center(BILIVER) | not yet recruiting | — | 1,000 | Azienda USL Toscana CentroOTHER | 1 | Apr 29, 2026 | clinicaltrials |
| NCT07557394 | A Prospective Non-randomized Controlled Interventional Study on the Effect of Shouhui Tongbian Capsules Combined With Pancreatin Enteric-coated Capsules on Pancreatic Exocrine Function in Patients After Curative Resection for Pancreatic Cancer | not yet recruiting | Phase 4 | 80 | Shanghai General Hospital, Shanghai Jiao Tong University School of MedicineOTHER | 0 | Apr 29, 2026 | clinicaltrials |
| NCT07381309 | Oncolytic Virus (H101) + SBRT + Chemotherapy + Targeted Therapy + Immunotherapy for Unresectable CRLM(VVSHIP) | not yet recruiting | Phase 2 | 114 | Jun HuangOTHER | 1 | Apr 28, 2026 | clinicaltrials |
| NCT07543783 | Efficacy and Safety of Low-dose Bevacizumab Plus Adebrelimab Combined With Transarterial Chemoembolization Followed by Hepatic Arterial Infusion Chemotherapy (TACE-HAIC) as First-line Treatment for Unresectable Hepatocellular Carcinoma: A Single-arm Phase 2 Trial | not yet recruiting | Phase 2 | 38 | Third Affiliated Hospital, Sun Yat-Sen UniversityOTHER | 0 | Apr 28, 2026 | clinicaltrials |
| NCT07553767 | Efficacy and Safety of Pegylated Interferon Alpha-2β in Patients With Hepatitis B-related Hepatocellular Carcinoma After Radical Resection | not yet recruiting | Early Phase 1 | 156 | Ningbo No.2 HospitalOTHER | 1 | Apr 28, 2026 | clinicaltrials |
| NCT07553793 | Chimeric Antigen Receptor Macrophages Targeting c-MET for Advanced Stage of Pancreatic Cancer Patients | not yet recruiting | Phase 1 | 18 | Peking Union Medical College HospitalOTHER | 1 | Apr 28, 2026 | clinicaltrials |
| NCT07554742 | Non-Invasive Detection of claudin18.2 in Pancreatic and Gastric/Gastroesophageal Junction Cancer by [68Ga]Ga-NODAGA-SNA014 PET Imaging | not yet recruiting | — | 64 | Ruijin HospitalOTHER | 1 | Apr 28, 2026 | clinicaltrials |
| NCT07554807 | A Randomized, Double-blind, Placebo-controlled, Prospective, Multi-center Trial Evaluating the Improvement of Nutritional Status and Sarcopenia With Silkworm Pupa Tablets in Patients With Malignancies | not yet recruiting | Phase 3 | 480 | First Affiliated Hospital of Zhejiang UniversityOTHER | 1 | Apr 28, 2026 | clinicaltrials |
| NCT07244978 | Neoadjuvant Ivonescimab（AK112） Combined With Chemotherapy in Patients With Resectable Esophageal Squamous Cell Carcinoma | not yet recruiting | Phase 2 | 49 | Second Affiliated Hospital, Zhejiang University, School of MedicineOTHER | 1 | Apr 24, 2026 | clinicaltrials |
| NCT07549906 | Neoadjuvant Iparomlimab/Tuvonralimab Plus CAPEOX Versus Iparomlimab/Tuvonralimab Plus CAPEOX and Propranolol for Locally Advanced pMMR Colon Cancer: A Prospective, Single-Center, Multi-Cohort Study | not yet recruiting | Phase 2 | 45 | Sun Yat-sen UniversityOTHER | 0 | Apr 24, 2026 | clinicaltrials |
| NCT07551479 | SCRT Based iTNT vs. LCRT Based TNT for MSS Locally Advanced Rectal Cancer(TORCH-STAR) | not yet recruiting | Phase 3 | 612 | Fudan UniversityOTHER | 1 | Apr 24, 2026 | clinicaltrials |
| NCT07547033 | Superior Mesenteric Artery First Versus Standard Approach in Pancreaticoduodenectomy(EQUINOXE) | not yet recruiting | N/A | 150 | Assistance Publique - Hôpitaux de ParisOTHER | 1 | Apr 23, 2026 | clinicaltrials |
| NCT07543510 | Low-Dose Bevacizumab and Atezolizumab Combined With TACE-HAIC in Unresectable Hepatocellular Carcinoma | not yet recruiting | N/A | 38 | Third Affiliated Hospital, Sun Yat-Sen UniversityOTHER | 0 | Apr 22, 2026 | clinicaltrials |
| NCT07543848 | A Prospective, Multicenter, Single-Arm Phase II Exploratory Study of Serplulimab Combined With Oncolytic Virus H101, Short-Course Radiotherapy, and XELOX Chemotherapy as Total Neoadjuvant Treatment for Locally Advanced (cT1-3N0M0) Rectal Cancer | not yet recruiting | Phase 2 | 20 | Chongqing University Cancer HospitalOTHER | 1 | Apr 22, 2026 | clinicaltrials |
| NCT07544121 | Effect of Babao Dan Capsule Combined With Antiviral Therapy on the Incidence of Hepatocellular Carcinoma in Patients With Hepatitis B-related Cirrhosis | not yet recruiting | N/A | 1,034 | Nanfang Hospital, Southern Medical UniversityOTHER | 0 | Apr 22, 2026 | clinicaltrials |
| NCT07487402 | Safety and Efficacy of Metabolically Armed GPC3 CAR-T Cells Injection (Meta10-GPC3) in Patients With Unresectable Recurrent/Metastatic Hepatocellular Carcinoma | not yet recruiting | Early Phase 1 | 27 | Zhejiang UniversityOTHER | 1 | Apr 21, 2026 | clinicaltrials |
| NCT07528937 | Application of 3D Reconstruction for Preoperative Strategy of Locally Advanced Colon Cancer | not yet recruiting | N/A | 168 | Fundació d'investigació Sanitària de les Illes BalearsOTHER_GOV | 0 | Apr 21, 2026 | clinicaltrials |
| NCT07542704 | A Study to Investigate the Safety and Efficacy of KQB368 as Monotherapy in Participants With Advanced Solid Malignancies | not yet recruiting | Phase 1 | 48 | Kumquat Biosciences Inc.INDUSTRY | 0 | Apr 21, 2026 | clinicaltrials |
| NCT03301805 | A Phase II, EvaluateBLEX 404 Combined With Gemcitabine Monotherapy With Pancreatic Cancer | not yet recruiting | Phase 2 | 40 | Rgene CorporationINDUSTRY | 0 | Apr 20, 2026 | clinicaltrials |
| NCT06655142 | OSCAR II STUDY - The ONCObind CTC Removal Study | not yet recruiting | N/A | 120 | ExThera Medical CorporationINDUSTRY | 0 | Apr 17, 2026 | clinicaltrials |
| NCT07536321 | Diagnostic Accuracy and Prognostic Value of 18F FDG PET-CT in the Follow up of Patients With Colorectal Carcinoma. | not yet recruiting | — | 46 | Assiut UniversityOTHER | 0 | Apr 17, 2026 | clinicaltrials |
| NCT07537777 | Benmelstobart Plus Anlotinib Combined With SBRT for Patients With Hepatocellular Carcinoma Failing First-Line Targeted Therapy | not yet recruiting | Phase 2 | 29 | Nanfang Hospital, Southern Medical UniversityOTHER | 1 | Apr 17, 2026 | clinicaltrials |
| NCT07537946 | Local Consolidation After Sintilimab Plus Lenvatinib for Metastatic Liver Cancer | not yet recruiting | Phase 3 | 400 | Tongji HospitalOTHER | 1 | Apr 17, 2026 | clinicaltrials |
| NCT07537959 | Surgery Plus Systemic Therapy for Liver Cancer With Extrahepatic Metastases | not yet recruiting | N/A | 280 | Tongji HospitalOTHER | 1 | Apr 17, 2026 | clinicaltrials |
| NCT07537972 | Denosumab Strategy for Liver Cancer With Bone Metastases | not yet recruiting | Phase 2 | 50 | Tongji HospitalOTHER | 1 | Apr 17, 2026 | clinicaltrials |
| NCT07533357 | Tpex Subsets in Negative Tumor Draining Lymph Nodes for Predicting the Efficacy of PD 1 Inhibitors in Advanced or Recurrent Esophageal Squamous Cell Carcinoma | not yet recruiting | — | 158 | Fudan UniversityOTHER | 0 | Apr 16, 2026 | clinicaltrials |
| NCT07036978 | Metabolomic and Immune-Microbiome Profiling for Unresectable Pancreatic Cancer | not yet recruiting | — | 140 | Chang Gung Memorial HospitalOTHER | 1 | Apr 15, 2026 | clinicaltrials |
| NCT07513116 | Evaluating Intermittent Fasting In Individuals At High Risk ForPancreatic Cancer Undergoing Screening | not yet recruiting | N/A | 20 | M.D. Anderson Cancer CenterOTHER | 1 | Apr 14, 2026 | clinicaltrials |
| NCT07527520 | Neoadjuvant Moderately Hypofractionated Radiotherapy Combined With Chemotherapy and Immunotherapy for High-risk pMMR/MSS Locally Advanced Rectal Cancer: A Prospective, Multi-center Randomized Control Phase II Trial | not yet recruiting | Phase 2 | 165 | Fudan UniversityOTHER | 1 | Apr 14, 2026 | clinicaltrials |
| NCT07522411 | Sequential FOLFOX-HAIC-TACE Plus Sintilimab-Bevacizumab Neoadjuvant Therapy Versus Direct Resection in Resectable High-Risk Recurrence Hepatocellular Carcinoma | not yet recruiting | Phase 1 / Phase 2 | 100 | BinYong LiangOTHER | 0 | Apr 13, 2026 | clinicaltrials |
| NCT07523152 | Assessment of Sexual Quality of Life Following Local Treatment (Radiotherapy With or Without Surgery) in Patients With HPV-positive Pelvic Cancer: a Descriptive Longitudinal Study(SAPPHIRE) | not yet recruiting | N/A | 42 | Institut du Cancer de Montpellier - Val d'AurelleOTHER | 0 | Apr 13, 2026 | clinicaltrials |
| NCT07211230 | Collagenase Biobank Study | not yet recruiting | — | 107 | University of ChicagoOTHER | 1 | Apr 9, 2026 | clinicaltrials |
| NCT07518706 | Neoadjuvant Tislelizumab-Lenvatinib vs Surgery Alone in Stage Ia HCC With Narrow Margin | not yet recruiting | Phase 2 | 60 | Tianjin Medical University Cancer Institute and HospitalOTHER | 0 | Apr 9, 2026 | clinicaltrials |
| NCT07516392 | Study of a Polygenic Risk Score to Predict the Risk of Pancreatic Ductal Adenocarcinoma(PRE-PDAC) | not yet recruiting | N/A | 1,140 | Catholic University of the Sacred HeartOTHER | 0 | Apr 8, 2026 | clinicaltrials |
| NCT07514429 | Regorafenib After Failure of Lenvatinib in Patients With Unresectable HCC: The RELEVANT-HCC Trial(RELEVANT-HCC) | not yet recruiting | Phase 2 | 24 | Ju Hyun ShimOTHER | 1 | Apr 7, 2026 | clinicaltrials |
| NCT07514455 | Regorafenib After Treatment Failure of First Line Immune Checkpoint Inhibitor Treatment in Advanced Hepatocellular Carcinoma Patients(RECOMEND) | not yet recruiting | Phase 2 | 20 | Ju Hyun ShimOTHER | 1 | Apr 7, 2026 | clinicaltrials |
| NCT07514533 | The Efficacy and Safety of Pucotenlimab (PD-1) Combined With Becotatugvedotin (EGFR-ADC) in Advanced Cholangiocarcinoma | not yet recruiting | Phase 2 | 60 | Sir Run Run Shaw HospitalOTHER | 0 | Apr 7, 2026 | clinicaltrials |
| NCT07515469 | A Prospective, Single-Arm, Exploratory Study of the Safety and Efficacy of Neoadjuvant Treatment With QL1706, an Anti-PD-1/Anti-CTLA-4 Bispecific Antibody, in Resectable Stage IB and IIA Hepatocellular Carcinoma With High Recurrence Risk | not yet recruiting | Phase 2 | 30 | Tianjin Medical University Cancer Institute and HospitalOTHER | 0 | Apr 7, 2026 | clinicaltrials |
| NCT07515625 | Efficacy of Sintilimab Combined With Bevacizumab and XELOX/SOX in Initially Unresectable AFP-positive Gastric/Gastroesophageal Junction Adenocarcinoma | not yet recruiting | Phase 2 | 46 | Fudan UniversityOTHER | 0 | Apr 7, 2026 | clinicaltrials |
| NCT07515820 | SHR-3821 in Advanced Colorectal Cancer: an Exploratory Study | not yet recruiting | Phase 2 | 12 | Meng QiuOTHER | 0 | Apr 7, 2026 | clinicaltrials |
| NCT07515950 | A COMPREHENSIVE BIOMARKER EVALUATION IN BILIARY TRACT CANCER(REVEAL-BTC) | not yet recruiting | — | 244 | MedSIROTHER | 0 | Apr 7, 2026 | clinicaltrials |
| NCT07516210 | Adaptive Radiotherapy for Safe Hypofractionation(ART-Hypo) | not yet recruiting | Phase 2 | 264 | Centre hospitalier de l'Université de Montréal (CHUM)OTHER | 1 | Apr 7, 2026 | clinicaltrials |
| NCT07497789 | SMYD3-Driven Metabolic Rewiring in Colorectal Liver Metastases(AIRC_ IG 34634) | not yet recruiting | — | 156 | Azienda Ospedaliera Specializzata in Gastroenterologia Saverio de BellisOTHER | 0 | Apr 6, 2026 | clinicaltrials |
| NCT07510867 | 18F-FAPI PET/CT and MRI in Gastric Cancer | not yet recruiting | — | 230 | First Affiliated Hospital of Zhejiang UniversityOTHER | 1 | Apr 6, 2026 | clinicaltrials |
Data updated 23 days agoSource updated Apr 30, 2026source: clinicaltrials