Non-Invasive Detection of claudin18.2 in Pancreatic and Gastric/Gastroesophageal Junction Cancer by [68Ga]Ga-NODAGA-SNA014 PET Imaging

Inclusion Criteria:

1. Participants with histopathologically confirmed pancreatic cancer and gastric/gastroesophageal junction cancer with claudin 18.2 expression of any level, including treatment-naive patients with upfront resectable disease, patients with post-operative recurrent disease who are or become resectable following treatment, and patients rendered resectable after neoadjuvant or conversion therapy.
2. Signed and dated informed consent form.
3. Commitment to comply with research procedures and co-operation in the implementation of the full research process.
4. Male or female participants.
5. Aged 18-75 years old.
6. Good general performance status with an expected overall survival of more than 6 months.

Exclusion Criteria:

1. Participants with prior Claudin 18.2 targeted therapy.
2. Participants with concurrent other active malignancies.
3. Participants with severe medical conditions that render them unsuitable for participation in this clinical study. Such as severe heart and lung failure, severe bone marrow suppression, severe liver and kidney dysfunction, etc.
4. Pregnant women and women who may be pregnant, women who are breastfeeding.
5. Participants with poor compliance.