Cancer Family
Malignant Digestive System Neoplasm
CI-CAN-00000229Explore in graph →
4,262 active trials43 approved drugs556 evidence items
Loading cancer entity…
Loading cancer entity…
Cancer Family
CI-CAN-00000229Explore in graph →
Clinical trials
19,108 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
Computedformula ci-trial-intel-v1 · interventional studies · entity + NCIt descendants · hover a figure for its formulaCompare cancersTerminated studies (2,001)
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT04196075 | The Effect of Andrographis Paniculata (AP) on Palliative Management of Advanced Esophageal Cancer(AP) | completed | Phase 3 | 30 | Chinese University of Hong KongOTHER | 1 | Nov 8, 2021 | clinicaltrials |
| NCT02395640 | The Comparison of XELOX and EOX in the First-line Treatment of Advanced Gastric Cancer | completed | Phase 3 | 438 | Fudan UniversityOTHER | 1 | Oct 26, 2021 | clinicaltrials |
| NCT00070213 | Leucovorin and Fluorouracil With or Without Oxaliplatin Compared to Capecitabine With or Without Oxaliplatin in Treating Patients With Metastatic Colorectal Cancer | completed | Phase 3 | 460 | Medical Research CouncilOTHER_GOV | 1 | Sep 27, 2021 | clinicaltrials |
| NCT02314117 | A Study of Ramucirumab (LY3009806) in Combination With Capecitabine and Cisplatin in Participants With Stomach Cancer(RAINFALL) | completed | Phase 3 | 645 | Eli Lilly and CompanyINDUSTRY | 20 | Aug 26, 2021 | clinicaltrials |
| NCT01927497 | Biological Mesh Closure of the Pelvic Floor After Extralevator Abdomino Perineal Resection for Rectal Cancer(BIOPEX) | completed | Phase 3 | 104 | Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)OTHER | 1 | Aug 17, 2021 | clinicaltrials |
| NCT03093870 | Varlitinib in Combination With Capecitabine for Advanced or Metastatic Biliary Tract Cancer(TreeTopp) | completed | Phase 2 / Phase 3 | 151 | ASLAN PharmaceuticalsOTHER | 11 | Aug 3, 2021 | clinicaltrials |
| NCT02158988 | Cytoreductive Surgery (CRS) With/Without HIPEC in Gastric Cancer With Peritoneal Carcinomatosis(GASTRIPEC) | completed | Phase 3 | 105 | Charite University, Berlin, GermanyOTHER | 1 | Jul 29, 2021 | clinicaltrials |
| NCT02909478 | Aprepitant Without Steroid in Preventing Chemotherapy-induced Nausea and Vomiting in Patients With Colorectal Cancer | completed | Phase 3 | 315 | Sun Yat-sen UniversityOTHER | 1 | Jul 29, 2021 | clinicaltrials |
| NCT03196791 | Compare the Oncological Benefit of Deep Neuromuscular Block in Gastric Cancer Obesity Patient | completed | Phase 3 | 196 | Korea University Anam HospitalOTHER | 1 | Jul 12, 2021 | clinicaltrials |
| NCT00487695 | Confocal Endomicroscopy for Barrett's Esophagus(CEBE) | completed | Phase 3 | 46 | Johns Hopkins UniversityOTHER | 1 | Jun 22, 2021 | clinicaltrials |
| NCT01655693 | Efficacy and Safety Doxorubicin Transdrug Study in Patients Suffering From Advanced Hepatocellular Carcinoma(ReLive) | completed | Phase 3 | 397 | Valerio TherapeuticsINDUSTRY | 11 | Jun 2, 2021 | clinicaltrials |
| NCT01455831 | Extended Peri-operative Tinzaparin to Improve Disease-free Survival in Patients With Resectable Colorectal Cancer(PERIOP-01) | completed | Phase 3 | 616 | Ottawa Hospital Research InstituteOTHER | 3 | May 17, 2021 | clinicaltrials |
| NCT01908426 | Study of Cabozantinib (XL184) vs Placebo in Subjects With Hepatocellular Carcinoma Who Have Received Prior Sorafenib(CELESTIAL) | completed | Phase 3 | 707 | ExelixisINDUSTRY | 19 | May 6, 2021 | clinicaltrials |
| NCT01755767 | Study of Tivantinib in Subjects With Inoperable Hepatocellular Carcinoma (HCC) Who Have Been Treated With One Prior Therapy(METIV-HCC) | completed | Phase 3 | 383 | Daiichi SankyoINDUSTRY | 16 | Apr 6, 2021 | clinicaltrials |
| NCT00112658 | Combination Chemotherapy as First-Line Therapy in Treating Patients With Metastatic Pancreatic Cancer | completed | Phase 2 / Phase 3 | 342 | UNICANCEROTHER | 1 | Mar 8, 2021 | clinicaltrials |
| NCT02138422 | A Phase 3 Study to Evaluate Xilonix as an Anticancer Therapy in Patients With Symptomatic Colorectal Cancer | completed | Phase 3 | 276 | Janssen Research & Development, LLCINDUSTRY | 1 | Mar 1, 2021 | clinicaltrials |
| NCT00002883 | Surgery With or Without Combination Chemotherapy in Treating Patients With Cancer of the Esophagus | completed | Phase 3 | 250 | UNICANCEROTHER | 1 | Feb 23, 2021 | clinicaltrials |
| NCT00003652 | Combination Chemotherapy Plus Radiation Therapy in Treating Patients With Stage II or Stage III Anal Cancer | completed | Phase 3 | 350 | UNICANCEROTHER | 1 | Feb 17, 2021 | clinicaltrials |
| NCT00005979 | Combination Chemotherapy With or Without Irinotecan in Treating Patients With Stage III Colon Cancer | completed | Phase 3 | — | UNICANCEROTHER | 1 | Feb 17, 2021 | clinicaltrials |
| NCT00227747 | Radiation Therapy and Capecitabine With or Without Oxaliplatin in Treating Patients Who Are Undergoing Surgery for Stage II or Stage III Rectal Cancer | completed | Phase 3 | 598 | UNICANCEROTHER | 1 | Feb 17, 2021 | clinicaltrials |
| NCT02644408 | Megestrol Acetate for the Improvement of Quality of Life in Esophageal Cancer With Chemoradiotherapy | completed | Phase 3 | 184 | The First Affiliated Hospital of Henan University of Science and TechnologyOTHER | 1 | Feb 17, 2021 | clinicaltrials |
| NCT03031444 | Perioperative Chemotherapy Plus Cetuximab Versus Chemotherapy Alone for High Risk Resectable Colorectal Liver Metastasis(PARECEC) | completed | Phase 2 / Phase 3 | 135 | Peking University Cancer Hospital & InstituteOTHER | 1 | Feb 1, 2021 | clinicaltrials |
| NCT03288987 | Comparing Efficacy and Safety of Stivant (AryoGen Bevacizumab) Versus Avastin in Metastatic Colorectal Cancer | completed | Phase 3 | 126 | AryoGen Pharmed Co.INDUSTRY | 1 | Jan 22, 2021 | clinicaltrials |
| NCT01224392 | Simultaneous Integrated Boost Preoperative Radiotherapy for Rectum Cancer(RectumSIB) | completed | Phase 3 | 156 | Universitair Ziekenhuis BrusselOTHER | 1 | Dec 30, 2020 | clinicaltrials |
| NCT01774786 | A Study of Pertuzumab in Combination With Trastuzumab and Chemotherapy in Participants With Human Epidermal Growth Factor Receptor 2 (HER2)-Positive Metastatic Gastroesophageal Junction or Gastric Cancer(JACOB) | completed | Phase 3 | 780 | Hoffmann-La RocheINDUSTRY | 32 | Dec 30, 2020 | clinicaltrials |
| NCT03164382 | Hepatic Arterial Infusion of Oxaliplatin, Fluorouracil/Leucovorin Versus Sorafenib in Advanced Hepatocellular Carcinoma | completed | Phase 3 | 262 | Sun Yat-sen UniversityOTHER | 1 | Dec 16, 2020 | clinicaltrials |
| NCT01500993 | Capecitabine in the Perioperative Treatment of Rectal Cancer(Rektum-III) | completed | Phase 3 | 401 | Universitätsmedizin MannheimOTHER | 1 | Nov 27, 2020 | clinicaltrials |
| NCT01955837 | Study of Trifluridine/Tipiracil (TAS-102) in Patients With Metastatic Colorectal Cancer in Asia(TERRA) | completed | Phase 3 | 406 | Taiho Pharmaceutical Co., Ltd.INDUSTRY | 3 | Nov 17, 2020 | clinicaltrials |
| NCT00265811 | Combination Chemotherapy With or Without Cetuximab in Treating Patients With Stage III Colon Cancer That Was Completely Removed By Surgery | completed | Phase 3 | 2,559 | Federation Francophone de Cancerologie DigestiveOTHER | 1 | Nov 9, 2020 | clinicaltrials |
| NCT02114359 | Chemotherapy Options for the First Line Chemotherapy in Elderly Patient With Advanced Gastric Cancer | completed | Phase 3 | 111 | Seoul National University HospitalOTHER | 1 | Oct 23, 2020 | clinicaltrials |
| NCT02340728 | Endoscopic Biliary Co-axial Stent Placement Plus/Minus Use of Radiofrequency Ablation (RFA) for Clearance of Occluded Self Expandable Metal Stents (SEMS) in Patients With Distal Biliary Obstruction From Unresectable Biliary-pancreatic Malignancies | completed | Phase 3 | 24 | Memorial Sloan Kettering Cancer CenterOTHER | 1 | Oct 22, 2020 | clinicaltrials |
| NCT01107639 | Radiation Therapy and Chemotherapy, With or Without Cetuximab, Followed by Surgery in Treating Patients With Locally Advanced Esophageal Cancer That Can Be Removed by Surgery | completed | Phase 3 | 297 | Swiss Cancer InstituteOTHER | 5 | Oct 20, 2020 | clinicaltrials |
| NCT02923921 | Study of Pegilodecakin (LY3500518) With FOLFOX Compared to FOLFOX Alone Second-line Tx in Participants With Metastatic Pancreatic Cancer(Sequoia) | completed | Phase 3 | 567 | Eli Lilly and CompanyINDUSTRY | 13 | Oct 19, 2020 | clinicaltrials |
| NCT02813967 | S-1 Concurrent With Radiotherapy Versus Radiotherapy for Elderly Patients With Esophageal Cancer | completed | Phase 3 | 298 | Zhejiang Cancer HospitalOTHER | 1 | Sep 16, 2020 | clinicaltrials |
| NCT01774344 | Study of Regorafenib After Sorafenib in Patients With Hepatocellular Carcinoma(RESORCE) | completed | Phase 3 | 573 | BayerINDUSTRY | 21 | Aug 20, 2020 | clinicaltrials |
| NCT02581462 | FLOT vs. FLOT/Herceptin/Pertuzumab for Perioperative Therapy of HER-2 Expressing Gastric or GEJ Cancer(PETRARCA) | completed | Phase 2 / Phase 3 | 81 | Institut für Klinische Krebsforschung IKF GmbH at Krankenhaus NordwestOTHER | 1 | Aug 11, 2020 | clinicaltrials |
| NCT01164722 | Infrared Coagulator Ablation or Observation in Preventing Anal Cancer in HIV-Positive Patients With Anal Neoplasia | completed | Phase 3 | 120 | AIDS Malignancy ConsortiumNETWORK | 1 | Aug 4, 2020 | clinicaltrials |
| NCT00020787 | Vaccine Therapy Plus Chemotherapy in Treating Patients With Metastatic or Locally Recurrent Stomach Cancer or Esophageal Cancer | completed | Phase 3 | 8 | Jonsson Comprehensive Cancer CenterOTHER | 1 | Aug 3, 2020 | clinicaltrials |
| NCT03565354 | Efficacy of Preoperative Intravenous Iron in Anaemic Colorectal Cancer Surgical Patients | completed | Phase 3 | 40 | Prince of Wales Hospital, Shatin, Hong KongOTHER | 1 | Jul 20, 2020 | clinicaltrials |
| NCT01072981 | Immunotherapy Study for Surgically Resected Pancreatic Cancer | completed | Phase 3 | 722 | NewLink Genetics CorporationINDUSTRY | 1 | May 28, 2020 | clinicaltrials |
| NCT02545504 | Andecaliximab With mFOLFOX6 as First Line Treatment for Advanced Gastric or Gastroesophageal Junction Adenocarcinoma(GAMMA-1) | completed | Phase 3 | 432 | Gilead SciencesINDUSTRY | 16 | May 26, 2020 | clinicaltrials |
| NCT00052910 | Chemotherapy and Radiation Therapy After Surgery in Treating Patients With Stomach or Esophageal Cancer | completed | Phase 3 | 546 | Alliance for Clinical Trials in OncologyOTHER | 2 | May 7, 2020 | clinicaltrials |
| NCT00726622 | Laparoscopic-Assisted Resection or Open Resection in Treating Patients With Rectal Cancer | completed | Phase 3 | 486 | Alliance for Clinical Trials in OncologyOTHER | 2 | May 7, 2020 | clinicaltrials |
| NCT00003594 | Combination Chemotherapy in Treating Patients With Advanced Colorectal Cancer | completed | Phase 3 | 1,691 | Alliance for Clinical Trials in OncologyOTHER | 4 | Apr 29, 2020 | clinicaltrials |
| NCT04342676 | Lymph Node Ratio and Kras Mutation in R Colon Cancer | completed | Phase 3 | 433 | Mansoura UniversityOTHER | 1 | Apr 13, 2020 | clinicaltrials |
| NCT00002570 | Immediate Compared With Delayed Chemotherapy in Advanced Colorectal Cancer Without Signs or Symptoms of Disease | completed | Phase 3 | 67 | NCIC Clinical Trials GroupNETWORK | 1 | Apr 6, 2020 | clinicaltrials |
| NCT00003687 | Treatment for Chronic Pain in Patients With Advanced Cancer | completed | Phase 3 | 87 | NCIC Clinical Trials GroupNETWORK | 1 | Apr 3, 2020 | clinicaltrials |
| NCT00026338 | Gemcitabine With/Out Erlotinib in Unresectable Locally Advanced/Metastatic Pancreatic Cancer | completed | Phase 3 | 569 | NCIC Clinical Trials GroupNETWORK | 19 | Apr 2, 2020 | clinicaltrials |
| NCT00047112 | Surgery With or Without Radiation Therapy and Chemotherapy in Treating Patients With Esophageal Cancer | completed | Phase 3 | 195 | Federation Francophone de Cancerologie DigestiveOTHER | 4 | Mar 30, 2020 | clinicaltrials |
| NCT00952029 | Combination Chemotherapy and Bevacizumab With or Without Bevacizumab Maintenance Therapy in Treating Patients With Metastatic Colorectal Cancer | completed | Phase 2 / Phase 3 | 492 | Federation Francophone de Cancerologie DigestiveOTHER | 1 | Mar 30, 2020 | clinicaltrials |
Data updated 23 days agoSource updated Nov 8, 2021source: clinicaltrials