Subtype
Malignant Colorectal Neoplasm
CI-CAN-00005874Explore in graph →
1,565 active trials21 approved drugs382 evidence items
- NCIt
- C4978
- DOID
- 9256
- Other
- 1 more code
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Subtype
CI-CAN-00005874Explore in graph →
Clinical trials
7,294 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
Computedformula ci-trial-intel-v1 · interventional studies · entity + NCIt descendants · hover a figure for its formulaCompare cancersTerminated studies (722)
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT05462236 | MNK Inhibitor AUM001 in Combination With Either Pembrolizumab or Irinotecan to Treat Metastatic Colorectal Cancer | recruiting | Phase 2 | 120 | AUM Biosciences Pte LtdOTHER | 1 | Jul 9, 2024 | clinicaltrials |
| NCT06314646 | Transanal Transection and Single-stapled Anastomosis (TTSS) in Rectal Cancer Patients(TTSS-REC) | recruiting | — | 472 | Istituto Clinico HumanitasOTHER | 1 | Jun 27, 2024 |
| clinicaltrials |
| NCT06385418 | Fluorouracil Treatment Via Colon for Colorectal Cancer | recruiting | Phase 2 | 40 | The Second Hospital of Nanjing Medical UniversityOTHER | 1 | Jun 26, 2024 | clinicaltrials |
| NCT05187338 | Triplex Checkpoint Inhibitors Therapy for Advanced Solid Tumors | recruiting | Phase 1 / Phase 2 | 100 | Second Affiliated Hospital of Guangzhou Medical UniversityOTHER | 1 | Jun 25, 2024 | clinicaltrials |
| NCT02864485 | Living Donor Liver Transplantation for Unresectable Colorectal Cancer Liver Metastases | recruiting | N/A | 20 | University Health Network, TorontoOTHER | 1 | Jun 18, 2024 | clinicaltrials |
| NCT04050345 | Tracking Mutations in Cell Free Tumour DNA to Predict Relapse in Early Colorectal Cancer(TRACC) | recruiting | — | 1,000 | Royal Marsden NHS Foundation TrustOTHER | 1 | Jun 14, 2024 | clinicaltrials |
| NCT06455124 | Short-course Radiotherapy Combined With CapeOx and PD-1 Inhibitor After Local Excision for High-risk Early Rectal Cancer (TORCH-LE) | recruiting | Phase 2 | 60 | Fudan UniversityOTHER | 1 | Jun 13, 2024 | clinicaltrials |
| NCT06449937 | Local Liver Treatment for Multi-organ Colorectal Cancer Metastases | recruiting | N/A | 130 | Anhui Provincial HospitalOTHER_GOV | 1 | Jun 10, 2024 | clinicaltrials |
| NCT06446050 | Chemokine and Co-stimulatory Molecule-modified Mesenchymal Stem Cells for the Treatment of Advanced Colorectal Cancer | recruiting | Early Phase 1 | 30 | Shanghai East HospitalOTHER | 1 | Jun 6, 2024 | clinicaltrials |
| NCT03349762 | Huaier Granules for Prevention of Recurrence and Metastasis of Colorectal Cancer Patients Following Radical Surgery | recruiting | — | 3,060 | Xi Shan WangOTHER | 1 | Jun 3, 2024 | clinicaltrials |
| NCT05954078 | Circulating Tumor DNA Methylation Guided Postoperative Adjuvant Chemotherapy for High-risk Stage II/III Colorectal Cancer | recruiting | Phase 3 | 340 | Fudan UniversityOTHER | 1 | May 20, 2024 | clinicaltrials |
| NCT06167967 | Circulating Tumor DNA Methylation Guiding Postoperative Adjuvant Chemotherapy in Stage III Colorectal Cancer(cmPAT) | recruiting | N/A | 990 | Sir Run Run Shaw HospitalOTHER | 1 | May 17, 2024 | clinicaltrials |
| NCT05927584 | Local Excision for Organ Preservation in Early REctal Cancer With No Adjuvant Treatment(LORENA) | recruiting | — | 145 | Fundación de Investigación Biomédica - Hospital Universitario de La PrincesaOTHER | 1 | May 14, 2024 | clinicaltrials |
| NCT06403735 | A Phase I Clinical Study of QLC1101 in Patients With Advanced Solid Tumors | recruiting | Phase 1 | 250 | Qilu Pharmaceutical Co., Ltd.INDUSTRY | 1 | May 8, 2024 | clinicaltrials |
| NCT06405776 | Effect of Lidocaine on Postoperative Pain and Long-term Survival in Elderly Patients Undergoing Colorectal Surgery | recruiting | N/A | 276 | West China HospitalOTHER | 1 | May 8, 2024 | clinicaltrials |
| NCT05539677 | Biobank and Register of Patients With Agresive Tumors for Translational and Analytical Research(REGATA) | recruiting | — | 1,000 | N.N. Petrov National Medical Research Center of OncologyOTHER | 1 | May 6, 2024 | clinicaltrials |
| NCT05228431 | Modified Sandwich Therapeutic Regimen for Locally Advanced Rectal Cancer | recruiting | Phase 2 | 121 | Zhen-Hai LuOTHER | 1 | Apr 22, 2024 | clinicaltrials |
| NCT05485077 | A Prospective Cohort Study on Colorectal Cancer Screening in Community Population | recruiting | — | 18,000 | Singlera Genomics Inc.INDUSTRY | 1 | Apr 17, 2024 | clinicaltrials |
| NCT03465982 | Timing to Minimally Invasive Surgery After Neoadjuvant Chemoradiotherapy for Rectal Cancer(TiMiSNAR) | recruiting | N/A | 340 | Azienda Ospedaliera SS. Antonio e Biagio e Cesare Arrigo di AlessandriaOTHER | 1 | Apr 16, 2024 | clinicaltrials |
| NCT05714124 | Liver Embolization Approaches for Tumor Management(LEATUM) | recruiting | — | 580 | IRCCS San RaffaeleOTHER | 1 | Apr 12, 2024 | clinicaltrials |
| NCT06350370 | Short-term and Long-term Outcomes of Colorectal Cancer Treated With Natural Orifice Specimen Extraction Surgery : a National Registry-based Study | recruiting | N/A | 8,000 | Cancer Institute and Hospital, Chinese Academy of Medical SciencesOTHER | 1 | Apr 5, 2024 | clinicaltrials |
| NCT06202001 | Irinotecan, TAS-102 Plus Bevacizumab as a Second-Line Therapy in mCRC Patients | recruiting | Phase 1 / Phase 2 | 70 | Cancer Institute and Hospital, Chinese Academy of Medical SciencesOTHER | 1 | Apr 2, 2024 | clinicaltrials |
| NCT06331988 | Microbiome, Immune-system and Tumor Interaction in Colorectal Cancer(MITICO) | recruiting | — | 320 | European Institute of OncologyOTHER | 1 | Mar 27, 2024 | clinicaltrials |
| NCT06326879 | A Comparative Study Between Early Onset Colorectal Cancer and Late Onset Colorectal Cancer Patients(EOrOS) | recruiting | — | 340 | Istituto Clinico HumanitasOTHER | 1 | Mar 25, 2024 | clinicaltrials |
| NCT06265025 | GM103 Intratumoral Injection in Patients With Locally Advanced, Unresectable, Refractory and/or Metastatic Solid Tumors | recruiting | Phase 1 / Phase 2 | 125 | GeneMedicine Co., Ltd.INDUSTRY | 1 | Mar 21, 2024 | clinicaltrials |
| NCT05224518 | Exercise Intervention to Improve Quality of Life in Patients With Colorectal Cancer | recruiting | N/A | 106 | National Taiwan University Hospital Hsin-Chu BranchOTHER | 1 | Mar 19, 2024 | clinicaltrials |
| NCT05883800 | Total Neoadjuvant Treatment Combined With Adaptive Radiotherapy for Rectal Cancer(TNT-RECORD) | recruiting | N/A | 61 | Haukeland University HospitalOTHER | 1 | Mar 19, 2024 | clinicaltrials |
| NCT06234007 | Short-course Radiotherapy Followed by Fruquintinib Plus Adebrelimab and CAPOX in the Full Course Neoadjuvant Treatment of Locally Advanced Rectal Cancer: a Multicenter, Single-arm, Open-label Study | recruiting | Phase 2 | 45 | Union Hospital, Tongji Medical College, Huazhong University of Science and TechnologyOTHER | 1 | Mar 18, 2024 | clinicaltrials |
| NCT06307249 | Precision Therapy for Solid Tumors: Synergistic CDK4/6 Inhibition and Anti-VEGF Targeting LncRNA(PTST_PALBEVA) | recruiting | Phase 1 | 50 | Lebanese UniversityOTHER | 1 | Mar 12, 2024 | clinicaltrials |
| NCT06293014 | TAS-102 Combined With Bevacizumab for Second-line Maintenance Treatment of Advanced Colorectal Cancer | recruiting | Phase 2 | 224 | Henan Cancer HospitalOTHER_GOV | 1 | Mar 5, 2024 | clinicaltrials |
| NCT06281145 | Stress-Reducing Intervention in Patients With Colorectal and Breast Cancer(SRI-BrCa_CRC) | recruiting | N/A | 100 | Comenius UniversityOTHER | 1 | Feb 28, 2024 | clinicaltrials |
| NCT05495048 | Transvaginal NOSES Versus Conventional Laparoscopic Surgery for Right Hemicolectomy | recruiting | N/A | 356 | Shanghai Minimally Invasive Surgery CenterOTHER | 1 | Feb 26, 2024 | clinicaltrials |
| NCT06270017 | Evaluation of Metastatic Disease and Oncological Treatment in Patients With Colon Cancer Using Zebra Fish Avatars(ZEBRA-COLON) | recruiting | Phase 1 / Phase 2 | 300 | University Hospital, LinkoepingOTHER | 1 | Feb 21, 2024 | clinicaltrials |
| NCT06266832 | The Efficacy and Safety of Short-course Radiation Combined With Adebrelimab and CAPEOX Neo-adjuvant Therapy for Organ-retention in Patients With MSS/pMMR Ultra Low Rectal Adenocarcinoma | recruiting | Phase 2 | 30 | Sir Run Run Shaw HospitalOTHER | 1 | Feb 20, 2024 | clinicaltrials |
| NCT06057350 | Surgery Versus Endoscopic Resection for Incompletely Removed Early Colon CAnceR(SCAR) | recruiting | N/A | 304 | Norwegian Department of Health and Social AffairsOTHER_GOV | 2 | Feb 16, 2024 | clinicaltrials |
| NCT05007132 | Trifluridine/ Tipiracil Plus Panitumumab Versus Trifluridine/ Tipiracil Plus Bevacizumab as First-line Treatment of Metastatic Colorectal Cancer | recruiting | Phase 2 | 153 | Dominik Paul ModestOTHER | 1 | Feb 15, 2024 | clinicaltrials |
| NCT06254521 | The Effects of Neoadjuvant Tislelizumab Combined With Chemotherapy in Locally Advanced MSS Rectal Cancer | recruiting | Phase 2 | 60 | First Affiliated Hospital of Guangxi Medical UniversityOTHER | 1 | Feb 12, 2024 | clinicaltrials |
| NCT04282044 | Study of CRX100 as Monotherapy and in Combination With Pembrolizumab in Patients With Advanced Solid Malignancies | recruiting | Phase 1 | 60 | BioEclipse TherapeuticsINDUSTRY | 1 | Feb 8, 2024 | clinicaltrials |
| NCT01479608 | Liver Transplantation and Colorectal Cancer | recruiting | N/A | 25 | Oslo University HospitalOTHER | 1 | Feb 7, 2024 | clinicaltrials |
| NCT02215889 | Partial Liver Segment 2/3 Transplantation Study | recruiting | Phase 1 / Phase 2 | 20 | Oslo University HospitalOTHER | 1 | Feb 6, 2024 | clinicaltrials |
| NCT03494946 | Liver Transplantation Compared to Chemotherapy in Patients With ColoRectal Cancer(SECAIII) | recruiting | N/A | 30 | Oslo University HospitalOTHER | 1 | Feb 6, 2024 | clinicaltrials |
| NCT06242067 | Second-line Treatment of Metastatic Colorectal Cancer(BEV-TASIRI) | recruiting | Phase 2 | 50 | Qilu Hospital of Shandong UniversityOTHER | 1 | Feb 5, 2024 | clinicaltrials |
| NCT06220617 | Multi-omics Study for Early Detection of Colorectal Cancer (MOED-CRC) | recruiting | — | 3,600 | Zhejiang UniversityOTHER | 1 | Jan 30, 2024 | clinicaltrials |
| NCT06229041 | Total Neoadjuvant Treatment ±Immunotherapy for High Risk Locally Advanced Rectal Cancer (TNTi) | recruiting | Phase 3 | 472 | Peking University Cancer Hospital & InstituteOTHER | 1 | Jan 29, 2024 | clinicaltrials |
| NCT05746897 | A First-in-human, Phase I, Open-label, Multicenter Study of NM1F(Anti-PVRIG) in Patients With Advanced Solid Tumors | recruiting | Phase 1 | 38 | Hefei TG ImmunoPharma Co., Ltd.OTHER | 1 | Jan 26, 2024 | clinicaltrials |
| NCT06222255 | The Safety and Efficacy of Transanal Irrigation in Patients With Sleep Disturbance From Low Anterior Resection Syndrome After Rectal Cancer Surgery (TraLARS)(TraLARS) | recruiting | N/A | 52 | Seoul National University HospitalOTHER | 1 | Jan 24, 2024 | clinicaltrials |
| NCT04936581 | Patient Reported Outcomes Following Cancer of the Rectum(PROCaRe) | recruiting | — | 200 | University Hospital Gregorio MarañónOTHER | 1 | Jan 23, 2024 | clinicaltrials |
| NCT06218810 | Cadonilimab in Combination With Bevacizumab and FOLFOX Regimen for the First-Line Treatment of Advanced Unresectable MSS-Type, RAS-Mutated Metastatic Colorectal Cancer | recruiting | Phase 2 | 53 | Fudan UniversityOTHER | 1 | Jan 23, 2024 | clinicaltrials |
| NCT06204484 | MRD-guided Deferred Adjuvant Therapy in Resectable Early-stage Colon Cancer(MIRROR) | recruiting | N/A | 349 | Sun Yat-sen UniversityOTHER | 1 | Jan 12, 2024 | clinicaltrials |
| NCT05245474 | Neoadjuvant Long-course Chemoradiation Plus PD-1 Blockade for Mid-low Locally Advanced Rectal Cancer | recruiting | Phase 2 | 186 | Beijing Friendship HospitalOTHER | 1 | Jan 10, 2024 | clinicaltrials |
Data updated 22 days agoSource updated Jul 9, 2024source: clinicaltrials