Cancer
Malignant Central Nervous System Neoplasm
CI-CAN-00001115Explore in graph →
Top-level822 active trials5 approved drugs103 evidence items
Loading cancer entity…
Loading cancer entity…
Cancer
CI-CAN-00001115Explore in graph →
Clinical trials
2,864 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
Computedformula ci-trial-intel-v1 · interventional studies · entity + NCIt descendants · hover a figure for its formulaCompare cancersTerminated studies (419)
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT00970788 | A Pilot Study of Using Video Images in Advance Care Planning in Malignant Glioma Patients | completed | N/A | 50 | Massachusetts General HospitalOTHER | 1 | May 1, 2012 | clinicaltrials |
| NCT01167322 | Study of NPC-07 for Fluorescence-guided Resection of Malignant Gliomas | completed | Phase 3 | 45 | NobelpharmaINDUSTRY | 1 | Apr 27, 2012 | clinicaltrials |
| NCT00241670 |
| Fluorescence-guided Resection of Malignant Gliomas With 5-Aminolevulinic Acid |
| completed |
| Phase 3 |
| 415 |
| medac GmbHINDUSTRY |
| 0 |
| Apr 26, 2012 |
| clinicaltrials |
| NCT00404495 | Combination of Irinotecan and Temozolomide in Children With Brain Tumors. | completed | Phase 2 | 83 | PfizerINDUSTRY | 8 | Apr 18, 2012 | clinicaltrials |
| NCT00132158 | ZD1839 and Oral Irinotecan in Treating Young Patients With Refractory Solid Tumors | completed | Phase 1 | 19 | St. Jude Children's Research HospitalOTHER | 1 | Apr 17, 2012 | clinicaltrials |
| NCT01285414 | Verubulin, Radiation Therapy, and Temozolomide to Treat Patients With Newly Diagnosed Glioblastoma Multiforme | completed | Phase 2 | 5 | Myrexis Inc.INDUSTRY | 1 | Apr 11, 2012 | clinicaltrials |
| NCT00777686 | Measuring Non-Enhancing Glioblastoma Progression | completed | — | 7 | M.D. Anderson Cancer CenterOTHER | 1 | Mar 30, 2012 | clinicaltrials |
| NCT00581737 | Cognitive Functioning and Quality of Life in CNS Lymphoma | completed | — | 50 | Memorial Sloan Kettering Cancer CenterOTHER | 1 | Mar 5, 2012 | clinicaltrials |
| NCT00412542 | Thalidomide and Temozolomide or Camptothecin-11 (CPT-11) in Patients With Gliomas | completed | Phase 2 | 78 | M.D. Anderson Cancer CenterOTHER | 1 | Feb 28, 2012 | clinicaltrials |
| NCT00460395 | Surgery Versus Stereotactic Radiosurgery in the Treatment of Single Brain Metastasis: A Randomized Trial | completed | Phase 3 | 64 | M.D. Anderson Cancer CenterOTHER | 1 | Feb 24, 2012 | clinicaltrials |
| NCT01189513 | SCH-900105 in Recurrent Glioblastoma | withdrawn | Phase 1 | 0 | M.D. Anderson Cancer CenterOTHER | 0 | Feb 20, 2012 | clinicaltrials |
| NCT00036569 | A Phase II Study of Pegylated Interferon Alfa 2b (PEG-Intron(Trademark)) in Children With Diffuse Pontine Gliomas | completed | Phase 2 | 32 | National Cancer Institute (NCI)NIH | 1 | Feb 13, 2012 | clinicaltrials |
| NCT00973557 | The Effect of Monoclonal Vascular Endothelial Growth Factor (VEGF) Antibody (Bevacizumab) on Pituitary Function | completed | — | 6 | Cedars-Sinai Medical CenterOTHER | 1 | Feb 7, 2012 | clinicaltrials |
| NCT00071539 | Safety and Efficacy Study to Treat Recurrent Grade 4 Malignant Brain Tumors | completed | Phase 2 | 56 | Teva Branded Pharmaceutical Products R&D, Inc.INDUSTRY | 0 | Jan 20, 2012 | clinicaltrials |
| NCT00508456 | Dietary Methionine Restriction Plus Temozolomide for Recurrent GBM | terminated | Phase 1 | 18 | M.D. Anderson Cancer CenterOTHER | 1 | Jan 16, 2012 | clinicaltrials |
| NCT00504660 | 6-TG, Capecitabine and Celecoxib Plus TMZ or CCNU for Anaplastic Glioma Patients | completed | Phase 2 | 75 | M.D. Anderson Cancer CenterOTHER | 1 | Jan 11, 2012 | clinicaltrials |
| NCT01105988 | Evaluating Tumor Pseudoprogression With FLT-PET and MRI | terminated | Early Phase 1 | 2 | Massachusetts General HospitalOTHER | 1 | Jan 6, 2012 | clinicaltrials |
| NCT01502241 | Phase III Trial of Primary Radio- or Chemotherapy in Malignant Astrocytoma of the Elderly(Methusalem) | completed | Phase 3 | 412 | Heidelberg UniversityOTHER | 2 | Dec 30, 2011 | clinicaltrials |
| NCT01441388 | A Study Of Crizotinib Plus VEGF Inhibitor Combinations In Patients With Advanced Solid Tumors. | withdrawn | Phase 1 | 0 | PfizerINDUSTRY | 0 | Dec 20, 2011 | clinicaltrials |
| NCT00790452 | Aspirin Prophylaxis for Venous Thromboembolism in Glioblastoma | terminated | Phase 2 | 1 | M.D. Anderson Cancer CenterOTHER | 1 | Dec 8, 2011 | clinicaltrials |
| NCT00817284 | Bevacizumab and Irinotecan or Bevacizumab and Temozolomide With Concomitant Radiotherapy for Primary Glioblastoma Multiforme (GBM) | completed | Phase 2 | 60 | Ulrik LassenOTHER | 1 | Nov 30, 2011 | clinicaltrials |
| NCT00892931 | Phase 2 Study MPC-6827 for Recurrent Glioblastoma Multiforme | completed | Phase 2 | 56 | Myrexis Inc.INDUSTRY | 1 | Oct 14, 2011 | clinicaltrials |
| NCT00002794 | Carboplatin Plus Vincristine in Treating Children With Retinoblastoma | completed | Phase 2 | 25 | St. Jude Children's Research HospitalOTHER | 1 | Oct 4, 2011 | clinicaltrials |
| NCT00004006 | Combination Chemotherapy, Radiation Therapy, and Bone Marrow Transplantation in Treating Patients With Retinoblastoma | completed | Phase 2 | 4 | St. Jude Children's Research HospitalOTHER | 1 | Oct 4, 2011 | clinicaltrials |
| NCT00515086 | Study of Everolimus (RAD001) in Patients With Recurrent Glioblastoma Multiforme (GBM) | terminated | Phase 2 | 41 | Novartis PharmaceuticalsINDUSTRY | 1 | Sep 22, 2011 | clinicaltrials |
| NCT00712062 | Study of Pemetrexed to Treat Recurrent or Progressive Primary Central Nervous System Lymphoma | withdrawn | Phase 2 | 0 | University of FloridaOTHER | 0 | Sep 20, 2011 | clinicaltrials |
| NCT00715013 | Patupilone (EPO 906) in Patients With Recurrent or Progressive Glioblastoma | completed | Phase 1 / Phase 2 | 9 | University of ZurichOTHER | 0 | Sep 15, 2011 | clinicaltrials |
| NCT00509301 | Safety & Radiation Distribution Study of Cotara® in Patients With Recurrent Glioblastoma Multiforme | completed | Phase 1 | 12 | Peregrine PharmaceuticalsINDUSTRY | 1 | Aug 5, 2011 | clinicaltrials |
| NCT01144988 | Avastin / Irinotecan in Patients With Recurrent or Progressive Malignant Glioma(AVIRMA01-09) | unknown | Phase 2 | 35 | Medical University InnsbruckOTHER | 1 | Aug 2, 2011 | clinicaltrials |
| NCT01124240 | Temozolomide and Procarbazine With Cilengitide for Patients With Glioblastoma Multiforme Without Methylation of the MGMT Promoter Gene(ExCentric) | unknown | Phase 2 | 48 | Northern Sydney and Central Coast Area Health ServiceOTHER | 1 | Jul 26, 2011 | clinicaltrials |
| NCT00010114 | Genetic Study of Newly Diagnosed Central Nervous System Tumors in Young Children | completed | — | 83 | Pediatric Brain Tumor ConsortiumNETWORK | 1 | Jul 20, 2011 | clinicaltrials |
| NCT00600054 | Phase 2 Study of Nimotuzumab in Pediatric Recurrent Diffuse Intrinsic Pontine Glioma | completed | Phase 2 | 44 | YM BioSciencesINDUSTRY | 3 | Jul 6, 2011 | clinicaltrials |
| NCT00089427 | IL13-PE38QQR Infusion After Tumor Resection, Followed by Radiation Therapy With or Without Temozolomide in Patients With Newly Diagnosed Malignant Glioma | completed | Phase 1 | 24 | INSYS Therapeutics IncINDUSTRY | 1 | Jul 4, 2011 | clinicaltrials |
| NCT00024557 | Histologic Effect/Safety of Pre/Post-Operative IL13-PE38QQR in Recurrent Resectable Supratentorial Malignant Glioma Patients | completed | Phase 1 | 40 | INSYS Therapeutics IncINDUSTRY | 1 | Jun 6, 2011 | clinicaltrials |
| NCT00041587 | Pre-operative IL13-PE38QQR in Patients With Recurrent or Progressive Malignant Glioma | completed | Phase 1 / Phase 2 | 80 | INSYS Therapeutics IncINDUSTRY | 3 | Jun 6, 2011 | clinicaltrials |
| NCT00064779 | Imaging Study of the Distribution of IL13-PE38QQR Infused Before and After Surgery in Adult Patients With Recurrent Malignant Glioma | completed | Phase 1 | 18 | INSYS Therapeutics IncINDUSTRY | 1 | Jun 6, 2011 | clinicaltrials |
| NCT00076986 | The PRECISE Trial: Study of IL13-PE38QQR Compared to GLIADEL Wafer in Patients With Recurrent Glioblastoma Multiforme | completed | Phase 3 | 300 | INSYS Therapeutics IncINDUSTRY | 6 | Jun 6, 2011 | clinicaltrials |
| NCT00062504 | Phase 2 Trial Using Talampanel in Patients With Recurrent High Grade Gliomas | terminated | Phase 2 | 30 | Teva Branded Pharmaceutical Products R&D, Inc.INDUSTRY | 0 | May 23, 2011 | clinicaltrials |
| NCT00104091 | Safety and Efficacy Study to Treat Recurrent Grade 4 Malignant Brain Tumors | completed | Phase 2 | 56 | Teva Branded Pharmaceutical Products R&D, Inc.INDUSTRY | 0 | May 23, 2011 | clinicaltrials |
| NCT00290771 | Efficacy and Safety of Imatinib Mesylate Plus Hydroxyurea (HU) in Patients With Recurrent Glioblastoma Multiforme (GBM) | terminated | Phase 2 | 231 | NovartisINDUSTRY | 1 | May 16, 2011 | clinicaltrials |
| NCT00154375 | Study of Imatinib Mesylate in Combination With Hydroxyurea Versus Hydroxyurea Alone as an Oral Therapy in Patients With Temozolomide Resistant Progressive Glioblastoma | completed | Phase 3 | 240 | Novartis PharmaceuticalsINDUSTRY | 1 | Apr 26, 2011 | clinicaltrials |
| NCT00686387 | Establishment of a Brain and Spinal Tumor Tissue Bank | unknown | — | 70 | Taipei Medical University WanFang HospitalOTHER | 1 | Apr 12, 2011 | clinicaltrials |
| NCT01181193 | Vitamin D for Treatment of Glioblastoma Multiforme | unknown | Phase 1 / Phase 2 | 20 | Soroka University Medical CenterOTHER | 1 | Mar 29, 2011 | clinicaltrials |
| NCT00635557 | Phase 1 Study of MPC-6827 and Carboplatin in Recurrent/Relapsed Glioblastoma Multiforme | unknown | Phase 1 / Phase 2 | 30 | Myrexis Inc.INDUSTRY | 1 | Mar 25, 2011 | clinicaltrials |
| NCT01317888 | Access Protocol for MAB-425 Radiolabeled With I-125 for High Grade Gliomas | unknown | N/A | 11 | Drexel UniversityOTHER | 0 | Mar 17, 2011 | clinicaltrials |
| NCT01308632 | Metronomic Temozolamide in Patients With Recurrent Glioblastoma | unknown | Phase 2 / Phase 3 | 30 | Grupo Español de Investigación en NeurooncologíaOTHER | 0 | Mar 4, 2011 | clinicaltrials |
| NCT00053118 | Chemotherapy and Stem Cell Transplantation in Treating Children With Central Nervous System Cancer | completed | Phase 1 | 1 | Roswell Park Cancer InstituteOTHER | 1 | Mar 1, 2011 | clinicaltrials |
| NCT00520936 | A Study of Pemetrexed in Children With Recurrent Cancer | completed | Phase 2 | 72 | Eli Lilly and CompanyINDUSTRY | 1 | Feb 25, 2011 | clinicaltrials |
| NCT00615186 | Glioblastoma Multiforme (GBM) Locoregional Agent Survival Study - Anti-tenascin Radiolabeled Antibody Therapy(Glass-Art) | terminated | Phase 3 | 9 | Bradmer Pharmaceuticals Inc.INDUSTRY | 0 | Feb 10, 2011 | clinicaltrials |
Data updated 23 days agoSource updated May 1, 2012source: clinicaltrials